Methyl Folate 800 mcg
KAL
Methyl Folate 800 mcg
4.9
★ ★ ★ ★ ★
(2356 ratings)
Folate 800 mcg
Score 95.0
A top-tier methylfolate supplement (Quatrefolic) at an optimal dose, offering superior bioavailability and excellent value, making it highly effective for comprehensive folate support.
Quantity: 90 Tablet(s)Servings size: 1 Tablet(s) (90 servings)
Selected goals:
Other goals:
General Health
Brain Health
Mood Support
Heart Health
leaderboard Score 95.0
A top-tier methylfolate supplement (Quatrefolic) at an optimal dose, offering superior bioavailability and excellent value, making it highly effective for comprehensive folate support.
insights Analysis
KAL Methyl Folate 800 mcg provides a potent dose of the active methylfolate, specifically (6S)-5-Methyltetrahydrofolate, Glucosamine Salt (Quatrefolic). This premium form is directly usable by the body, circumventing the need for conversion from synthetic folic acid, which is crucial for individuals with MTHFR genetic variations. The product's competitive price per serving for an active folate, coupled with a very high review count, underscores its effectiveness and broad appeal among users seeking a high-quality folate supplement.
- Uses a highly bioavailable and active methylfolate form (Quatrefolic), ensuring direct and efficient utilization by the body.
- Provides an excellent and clinically relevant dosage (800mcg) for comprehensive folate support.
- Very competitive price per serving for an active folate, offering exceptional value.
- High review count indicating widespread user satisfaction and perceived effectiveness.
- While generally well-regarded, specific brand availability might vary.
- Some individuals might prefer an even higher dose for certain therapeutic applications, though 800mcg is robust.
- Tablet/capsule form may not be preferred by those who prefer liquids or chewables.
$14.44($0.16 per serving)
 Amazon | $ 14.44 | |
 Walmart | $ 16.29 | |
 iHerb | $ 16.29 |
bolt Effectiveness for goals
Yes, adequate folate intake, especially before and during early pregnancy, is highly effective in preventing neural tube defects (NTDs) like spina bifida and anencephaly. This is why many prenatal supplements contain folic acid, the synthetic form of folate. Health organizations recommend women of childbearing age consume sufficient folate daily.
Folate is essential for cell growth and division, DNA synthesis and repair, and red blood cell formation. It plays a crucial role in various metabolic processes, including the metabolism of homocysteine. Many people take folate to support overall health and prevent deficiency.
Folate supplements are very effective in treating and resolving a folate deficiency. Deficiency can lead to megaloblastic anemia, fatigue, and other symptoms. Supplementation typically restores folate levels and alleviates associated symptoms.
Folic acid, the synthetic form found in supplements and fortified foods, is often considered more bioavailable than natural folate from foods. This is because folic acid is more stable and readily absorbed by the body. Once absorbed, both forms are converted to the active form of folate within the body to exert their effects.
Folate is crucial for the formation of red blood cells, which transport oxygen throughout the body, and it's involved in energy metabolism. A deficiency in folate can lead to megaloblastic anemia, causing symptoms like fatigue and low energy. Therefore, ensuring adequate folate intake can support healthy energy levels, especially if a deficiency is present.
schedule Dosage, timing & forms
For most adult men and women, the RDA is 400 micrograms (mcg) of dietary folate equivalents (DFEs) daily. Pregnant individuals are advised to consume 600 mcg DFE daily, and lactating individuals 500 mcg DFE. These recommendations help ensure adequate intake for essential bodily functions.
The two primary forms are folic acid, which is the synthetic form commonly used in fortified foods and supplements, and L-methylfolate (also known as 5-MTHF), which is the active, natural form of folate. Other forms like folinic acid are also available but less common. The choice of form may depend on individual needs or preferences.
Folic acid must be converted by the body into L-methylfolate to become biologically active. L-methylfolate, being the already active form, does not require this conversion. This difference can be significant for individuals with certain genetic variations that affect the conversion process.
Yes, there is an established Tolerable Upper Intake Level (UL) of 1,000 mcg (1 mg) per day for *synthetic folic acid* from supplements and fortified foods for adults. This UL is set because high intakes of folic acid can mask the symptoms of vitamin B12 deficiency. There is no UL established for folate from food sources or for L-methylfolate.
Supplemental dosages vary based on individual needs and health goals, but common doses often range from 400 mcg to 1,000 mcg (1 mg) daily. For specific needs, such as during pregnancy planning, healthcare providers may recommend higher doses of folic acid, often 800 mcg or more. Always consult a healthcare professional for personalized dosage advice.
health_and_safety Safety & interactions
Yes, high doses of Folate, especially folic acid, can mask a Vitamin B12 deficiency. Folate can correct the megaloblastic anemia associated with B12 deficiency, but it does not prevent the irreversible neurological damage that can progress if the underlying B12 deficiency remains untreated. This is a critical safety concern.
Yes, Folate can interact with certain medications. These include some anti-seizure drugs, methotrexate (used for cancer and autoimmune diseases), and drugs that reduce stomach acid, which may affect Folate absorption or effectiveness. It is advisable to consult a healthcare professional about potential interactions.
Folate is considered safe and is crucially important during pregnancy for fetal development, particularly to prevent neural tube defects. Supplementation with synthetic folic acid is widely recommended before and during early pregnancy. It is also safe and beneficial during breastfeeding.
While Folate is water-soluble, exceptionally high intakes, particularly from synthetic folic acid, may lead to certain side effects. These can include abdominal cramps, diarrhea, or sleep problems. The tolerable upper intake level is established for synthetic folic acid.
Folate supplements are generally well-tolerated at recommended doses. Mild, rare side effects might include nausea, bloating, or sleep disturbances. Consuming extremely high doses over time could potentially lead to other effects.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Folate | 800 mcg |
Categories
Folate 95.0
The product utilizes (6S)-5-Methyltetrahydrofolate, Glucosamine Salt (Quatrefolic), a premium, highly stable, and bioavailable form of active folate. This ensures efficient absorption and utilization, making it superior to synthetic folic acid for nearly all users and highly effective for various metabolic processes.
Goals
Brain Health 95.0
Methylfolate is directly involved in the synthesis of critical neurotransmitters and supports nerve tissue health. This active form is highly effective for enhancing cognitive function, memory, and overall brain health, particularly beneficial for those with impaired folate metabolism.
Mood Support 95.0
Through its direct support of the methylation cycle and neurotransmitter production, methylfolate is exceptionally effective for mood regulation, aiding in the alleviation of low mood symptoms and promoting emotional well-being by ensuring adequate biochemical pathways.
General Health 90.0
By supplying methylfolate, this product ensures optimal DNA synthesis, cell growth, and repair without metabolic hurdles, providing robust and foundational support for overall health and vitality for nearly all individuals.
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