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St. John's Wort 450 mg

Solaray
4.6
★ ★ ★ ★ ★
(436 ratings)
St. John's Wort 900 mg
Product Image
Score78
Focused dosing is convenient, yet unstandardized potency and major medication interactions make careful selection essential.
How scoring works
Quantity:100 VegCap(s) • (50 servings)
Goals:
Mood Support

Score 78

Focused dosing is convenient, yet unstandardized potency and major medication interactions make careful selection essential.
How scoring works
$19.99($0.39 per serving)
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Analysis

The 900 mg serving provides organic whole herb in a focused vegetable capsule format. No unrelated active ingredients dilute the intended mood-support role.

No hypericin or hyperforin standardization is given, so different batches may not deliver identical active strength. The large herb weight does not by itself establish clinical potency.

Adults with mild mood concerns who take no interacting medicines are the clearest audience. The two capsules format is convenient, but suitability depends more on medication compatibility than ease of use.

Who is it for
  • Adults seeking focused St. John’s wort support
  • People who take no interacting medicines
  • Users who prefer a vegetable capsule
Best for
  • Focused mood-support supplementation
  • Whole-herb St. John’s wort use
  • two capsules daily use

Pros

  • Focused single-herb formula
  • Clearly states a 900 mg serving
  • two capsules format

Cons

  • Hypericin and hyperforin are not standardized
  • Extensive medication interactions restrict use
  • Whole-herb potency can vary

Warnings

  • St. John’s wort can sharply reduce the effectiveness of oral contraceptives, warfarin, transplant medicines, HIV medicines, and many other drugs by speeding their clearance.
  • Combining St. John’s wort with SSRIs, SNRIs, MAO inhibitors, triptans, tramadol, or dextromethorphan can cause dangerous serotonin excess.
  • St. John’s wort can increase sensitivity to sunlight, so strong sun or UV exposure may require extra skin and eye protection.

Nutrient quality

79 High impact

The daily herb amount is substantial and directly relevant to mood support. Missing extract and active-marker details limit consistency and precise dose comparison.

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Ingredient transparency

75 High impact

The herb amount is clearly disclosed without a hidden blend. Active-marker strength, complete intake directions, and inactive ingredients are not supplied.

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Customer satisfaction

69 High impact

The supplied average rating is strong. A very large rating base makes the average dependable, but no detailed experience evidence was supplied.

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Value for money

88 Highest impact

Serving economics are favorable. Form or disclosure limits keep practical value moderate.

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Report analysis

Goals

Mood Support
Mood Support
Impact
High effect
B+ Goal FitA- Strength of SupportD CoverageA Formula Quality

St. John's Wort 450 mg provides 900 mg per serving and uses a St. John's wort extract with incomplete active-marker detail, giving it direct but dose-dependent alignment with mood support.

Customer feedback averages 4.57 from 505 reviews, while the published label carries medication-interaction cautions and a product-specific independent certification was not confirmed.

Study evidence
St. John's Wort Supportive 97 studies

Ingredients

IngredientAmount per serving
organic St. John's Wort
900 mg
Adults 18–50 Vegan Vegetarian
Report overview
St. John's Wort · 900 mg OverallScore72
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Solaray Saint John's Wort 450 mg provides 900 mg per serving and uses organic Saint John's wort without an extract or active-marker standard, producing a strong dosage fit under the collection rubric. Customer feedback averages 4.57 from 505 reviews, while the published label includes a specific interaction warning.

View ingredientView products
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Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort Extract 300 mg

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A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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St. John's Wort

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Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort