Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
Randomized trial59 participantsflagBrain Health flagCognitive Support flagEnergy forscienceAshwagandha
- Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
Randomized trial40 participantsflagBrain Health flagCognitive Support forscienceAshwagandha
- Efficacy of Withania somnifera supplementation on adult's cognition and mood.
Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
Randomized trial60 participantsflagBrain Health flagCognitive Support flagProductivity Boost forscienceAshwagandha
- A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
Randomized trial85 participantsflagBrain Health forscienceAshwagandha
- Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
Randomized trial130 participantsflagBrain Health flagSleep Support flagStress Relief forscienceAshwagandha
- Antenatal magnesium sulfate and neuroprotection.
Doyle LW · Current opinion in pediatrics · 2012
Meta-analysis6,145 participants5 studies pooledflagBrain Health forscienceMagnesium
- No. 376-Magnesium Sulphate for Fetal Neuroprotection.
Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020
Guideline / consensus4,446 participantsflagBrain Health forscienceMagnesium
- Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review.
Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA · Obstetrics and gynecology · 2024
Systematic review5,917 participants6 studies pooledflagBrain Health forscienceMagnesium
- Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.
Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A · BJOG : an international journal of obstetrics and gynaecology · 2020
Meta-analysis5,917 participants6 studies pooledflagBrain Health forscienceMagnesium
- Magnesium sulfate and fetal neuroprotection: overview of clinical evidence.
Chollat C; Marret S · Neural regeneration research · 2020
Narrative reviewflagBrain Health forscienceMagnesium
- Efficacy of Zinc Supplement in Minimal hepatic Encephalopathy: A prospective, Randomized Controlled Study (Zinc-MHE Trial).
Janyajirawong R; Vilaichone RK; Sethasine S · Asian Pacific journal of cancer prevention : APJCP · 2021
Randomized trial69 participantsflagBrain Health flagCognitive Support forscienceZinc
- A preliminary report: effects of zinc and micronutrient repletion on growth and neuropsychological function of urban Chinese children.
Penland JG; Sandstead HH; Alcock NW; Dayal HH; Chen XC; Li JS; Zhao F; Yang JJ · Journal of the American College of Nutrition · 1997
Randomized trial372 participantsflagBrain Health flagCognitive Support forscienceZinc
- Association between zinc deficiency and cognitive decline in community-dwelling older adults.
Marchetti MF; Silva GMD; Freiria CN; Borim FSA; Brito TRP; Milanski M; Corona LP · Ciencia & saude coletiva · 2022
Cross-sectional study591 participantsflagBrain Health forscienceZinc
- Zinc status, psychological and nutritional assessment in old people recruited in five European countries: Zincage study.
Marcellini F; Giuli C; Papa R; Gagliardi C; Dedoussis G; Herbein G; Fulop T; Monti D; Rink L; Jajte J; Mocchegiani E · Biogerontology · 2007
Cross-sectional study853 participantsflagBrain Health forscienceZinc
- Zinc alleviates stroke development through autophagy-mediated modulation of immune microenvironment.
Qiu Z; Liu X; Li J; Yin H; Luo J; Lin Z; Rexiati M; Abulaiti A; Yasen A; Xing L; Aili D; Meng B; Li X; You Z; He J; Huang C; Qian Z; Chen J · Frontiers in immunology · 2025
OtherflagBrain Health forscienceZinc
- A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
Randomized trial54 participantsflagCognitive Support forscienceAshwagandha
- Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
Randomized trial58 participantsflagCognitive Support forscienceAshwagandha
- Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
Meta-analysis6,145 participants5 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
Zhang C; Sun L; Sun H · Medicine · 2022
Meta-analysis1,899 participants22 studies pooledflagCognitive Support forscienceMagnesium
- Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
Randomized trial40 participantsflagCognitive Support forscienceMagnesium
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
Randomized trial80 participantsflagCognitive Support flagEnergy forscienceMagnesium
- Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM · Minerva anestesiologica · 2021
Randomized trial80 participantsflagCognitive Support forscienceMagnesium
- Effects of zinc supplementation on parent and teacher behaviour rating scores in low socioeconomic level Turkish primary school children.
Uçkardeş Y; Ozmert EN; Unal F; Yurdakök K · Acta paediatrica (Oslo, Norway : 1992) · 2009
Randomized trial226 participantsflagCognitive Support forscienceZinc
- L-shaped association between dietary zinc intake and cognitive decline in Chinese older people.
Meng Q; Liu M; Zu C; Su X; Wei Y; Gan X; Zhang Y; He P; Zhou C; Ye Z; Liu C; Qin X · Age and ageing · 2024
Cohort study3,106 participantsflagCognitive Support forscienceZinc
- The efficacy of zinc augmentation in children with attention deficit hyperactivity disorder under treatment with methylphenidate: A randomized controlled trial.
Noorazar SG; Malek A; Aghaei SM; Yasamineh N; Kalejahi P · Asian journal of psychiatry · 2021
Randomized trial60 participantsflagCognitive Support forscienceZinc
- Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
Randomized trial186 participantsflagEnergy flagMood Support forscienceAshwagandha
- Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial.
Prajapati H; Satia M; Shah D; Basera I; Shah T · Phytotherapy research : PTR · 2026
Randomized trialflagEnergy forscienceAshwagandha
- Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits.
Vittal M; Vinciguerra M · Biogerontology · 2025
Narrative reviewflagEnergy forscienceAshwagandha
- Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
Randomized trial120 participantsflagEnergy flagProductivity Boost forscienceAshwagandha
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
Cohort study81,524 participantsflagEnergy flagFitness forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C · Magnesium research · 2008
Narrative reviewflagEnergy forscienceMagnesium
- Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial.
Ziegenfuss TN; Kedia AW; Sandrock JE; Raub BJ; Kerksick CM; Lopez HL · Nutrients · 2019
Randomized trial38 participantsflagFitness forscienceAshwagandha
- Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.
Choudhary B; Shetty A; Langade DG · Ayu · 2016
Randomized trial50 participantsflagFitness flagGeneral Health forscienceAshwagandha
- Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO 2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.
Verma N; Gupta SK; Patil S; Tiwari S; Mishra AK · F1000Research · 2024
Randomized trial80 participantsflagFitness flagGeneral Health flagMuscle Gain forscienceAshwagandha
- Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
Meta-analysis1,249 participants20 studies pooledflagFitness flagMuscle Gain flagTestosterone Support forscienceAshwagandha
- Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists.
Shenoy S; Chaskar U; Sandhu JS; Paadhi MM · Journal of Ayurveda and integrative medicine · 2013
Randomized trial40 participantsflagFitness forscienceAshwagandha
- Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
Welch AA; Skinner J; Hickson M · Nutrients · 2018
Cross-sectional study156,575 participantsflagFitness flagMuscle Gain forscienceMagnesium
- Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
Cross-sectional study2,570 participantsflagFitness forscienceMagnesium
- Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
Randomized trial80 participantsflagFitness forscienceMagnesium
- Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
Systematic review45 studies pooledflagFitness forscienceMagnesium flagFitness forscienceZinc
- Association between composite dietary antioxidant index and handgrip strength in American adults: Data from National Health and Nutrition Examination Survey (NHANES, 2011-2014).
Wu D; Wang H; Wang W; Qing C; Zhang W; Gao X; Shi Y; Li Y; Zheng Z · Frontiers in nutrition · 2024
Cross-sectional study6,019 participantsflagFitness flagMuscle Gain forscienceZinc
- Serum essential elements and muscle health in Chinese adults: a community-based study.
Ye H; Wang D; Liu S; Yao N; Gui Z; Huang Z; Zeng Y; Liu L; Wan H; Shen J · Nutrition & metabolism · 2025
Cross-sectional study5,389 participantsflagFitness flagMuscle Gain forscienceZinc
- [Survey of the dietary status and physical activity level and fitness of college freshmen in Chengdu].
Han H; Lv X; Wang D · Wei sheng yan jiu = Journal of hygiene research · 2010
Cross-sectional study1,200 participantsflagFitness forscienceZinc
- A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM · Journal of the International Society of Sports Nutrition · 2026
Narrative reviewflagFitness forscienceZinc
- A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
Randomized trial150 participantsflagGeneral Health flagSleep Support forscienceAshwagandha
- Withania somnifera (L.) Dunal as Add-On Therapy for COPD Patients: A Randomized, Placebo-Controlled, Double-Blind Study.
Singh P; Salman KA; Shameem M; Warsi MS · Frontiers in pharmacology · 2022
Randomized trial150 participantsflagGeneral Health forscienceAshwagandha
- Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
Meta-analysis400 participants5 studies pooledflagGeneral Health flagProductivity Boost forscienceAshwagandha
- Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
Randomized trial113 participantsflagGeneral Health forscienceBoron
- Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
Randomized trialflagGeneral Health forscienceBoron
- The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
Clinical trial336 participantsflagGeneral Health forscienceBoron
- Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
Single-arm trial30 participantsflagGeneral Health forscienceBoron
- Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
Randomized trial78 participantsflagGeneral Health forscienceBoron
- Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
Meta-analysis1,257 participants20 studies pooledflagGeneral Health forscienceMagnesium
- Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
Woods KL; Fletcher S · Lancet (London, England) · 1994
Randomized trial2,316 participantsflagGeneral Health forscienceMagnesium
- Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
Cohort study10,999 participantsflagGeneral Health forscienceMagnesium
- Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
Cohort study9,359 participantsflagGeneral Health forscienceMagnesium
- The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
Randomized trial64 participantsflagGeneral Health forscienceMagnesium
- Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
Randomized trial144 participantsflagGeneral Health forscienceZinc
- Zinc supplementation in young children with acute diarrhea in India.
Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
Randomized trial937 participantsflagGeneral Health forscienceZinc
- Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
Randomized trial4,753 participantsflagGeneral Health forscienceZinc
- Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
Randomized trial84 participantsflagGeneral Health forscienceZinc
- Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
Randomized trial142 participantsflagGeneral Health forscienceZinc
- A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
Randomized trial141 participantsflagMood Support forscienceAshwagandha
- Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
Meta-analysis254 participants5 studies pooledflagMood Support forscienceAshwagandha
- A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
Randomized trial64 participantsflagMood Support flagStress Relief forscienceAshwagandha
- Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
Meta-analysis29 participants29 studies pooledflagMood Support forscienceAshwagandha
- Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
Meta-analysis4,049 participants52 studies pooledflagMood Support forscienceMagnesium
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
Randomized trial126 participantsflagMood Support flagStress Relief forscienceMagnesium
- Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
Randomized trial40 participantsflagMood Support forscienceMagnesium
- The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
Randomized trial46 participantsflagMood Support forscienceMagnesium
- Dietary magnesium intake and risk of depression.
Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
Cross-sectional study17,730 participantsflagMood Support forscienceMagnesium
- Zinc in depression: From development to treatment: A comparative/ dose response meta-analysis of observational studies and randomized controlled trials.
Yosaee S; Clark CCT; Keshtkaran Z; Ashourpour M; Keshani P; Soltani S · General hospital psychiatry · 2022
Meta-analysisflagMood Support forscienceZinc
- Dietary zinc and iron intake and risk of depression: A meta-analysis.
Li Z; Li B; Song X; Zhang D · Psychiatry research · 2017
Meta-analysis9 studies pooledflagMood Support forscienceZinc
- Zinc sulphate: A reasonable choice for depression management in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled clinical trial.
Salari S; Khomand P; Arasteh M; Yousefzamani B; Hassanzadeh K · Pharmacological reports : PR · 2016
Randomized trial43 participantsflagMood Support forscienceZinc
- Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis.
Cheng YC; Huang WL; Chen WY; Huang YC; Kuo PH; Tu YK · Psychological medicine · 2025
Meta-analysis17,437 participants192 studies pooledflagMood Support forscienceZinc
- Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
Sarris J; Ravindran A; Yatham LN; Marx W; Rucklidge JJ; McIntyre RS; Akhondzadeh S; Benedetti F; Caneo C; Cramer H; Cribb L; de Manincor M; Dean O; Deslandes AC; Freeman MP; Gangadhar B; Harvey BH; Kasper S; Lake J; Lopresti A; Lu L; Metri NJ; Mischoulon D; Ng CH; Nishi D; Rahimi R; Seedat S; Sinclair J; Su KP; Zhang ZJ; Berk M · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2022
Guideline / consensusflagMood Support forscienceZinc
- Ashwagandha Root Extract Stabilises Physiological Stress Responses in Male and Female Team Sports Athletes During Pre-Season Training.
Coope OC; Otaegui E; Suárez M; Levington A; Abad-Sangrà M; Lloyd B; Spurr TJ; Roman-Viñas B · Nutrients · 2026
Randomized trial56 participantsflagMuscle Gain forscienceAshwagandha
- Evaluation of Withania somnifera (L.) Dunal (Ashwagandha) on Physical Performance, Biomarkers of Inflammation, and Muscle Status in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled Study.
Raut A; Tripathi R; Marathe PA; Uchil DA; Agashe S; Rege N; Vaidya AB · Cureus · 2024
Randomized trialflagMuscle Gain forscienceAshwagandha
- Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
Wankhede S; Langade D; Joshi K; Sinha SR; Bhattacharyya S · Journal of the International Society of Sports Nutrition · 2016
Randomized trial57 participantsflagMuscle Gain forscienceAshwagandha
- Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics.
Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
Randomized trial49 participantsflagMuscle Gain forscienceMagnesium
- Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by 31P Magnetic Resonance Spectroscopy, Than With Serum Magnesium.
Cameron D; Welch AA; Adelnia F; Bergeron CM; Reiter DA; Dominguez LJ; Brennan NA; Fishbein KW; Spencer RG; Ferrucci L · Frontiers in physiology · 2020
Cross-sectional study441 participantsflagMuscle Gain forscienceMagnesium
- Effect of magnesium supplementation on strength training in humans.
Brilla LR; Haley TF · Journal of the American College of Nutrition · 1992
Clinical trial26 participantsflagMuscle Gain forscienceMagnesium
- Association Between Dietary Magnesium Intake and Low Muscle Mass: The Mediating Role of Inflammatory Indicators.
Zhu Z; Wang W; Ding F; Shen Y · Healthcare (Basel, Switzerland) · 2026
Cross-sectional study5,793 participantsflagMuscle Gain forscienceMagnesium
- Bioelectrical impedance vector analysis for evaluating zinc supplementation in prepubertal and healthy children.
Dantas MM; Rocha ÉD; Brito NJ; Alves CX; França MC; das Graças Almeida M; Brandão-Neto J · Food & nutrition research · 2015
Randomized trial60 participantsflagMuscle Gain forscienceZinc
- Dietary Zinc Intakes Are Associated With Skeletal Muscle Mass and Strength in Children and Adolescents: Zinc and Muscle in Children.
Kong FS; Ma CM · Clinical pediatrics · 2024
Cross-sectional studyflagMuscle Gain forscienceZinc
- Association of Serum Concentrations of Copper, Selenium, and Zinc with Grip Strength Based on NHANES 2013-2014.
Chen K; Zhou J; Liu N; Meng X · Biological trace element research · 2024
Cross-sectional studyflagMuscle Gain forscienceZinc
- Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
Randomized trial80 participantsflagProductivity Boost flagSleep Support forscienceAshwagandha
- Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
Randomized trial20 participantsflagProductivity Boost forscienceAshwagandha
- Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
Randomized trial135 participantsflagSleep Support forscienceAshwagandha
- Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
Randomized trial60 participantsflagSleep Support forscienceAshwagandha
- Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
Randomized trial320 participantsflagSleep Support forscienceMagnesium
- Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
Cohort study3,964 participantsflagSleep Support forscienceMagnesium
- Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
Randomized trial120 participantsflagSleep Support forscienceMagnesium
- The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
Randomized trial46 participantsflagSleep Support forscienceMagnesium
- A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
Randomized trial175 participantsflagSleep Support forscienceMagnesium
- An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
Mishra DN; Kumar M · Heliyon · 2024
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
Randomized trial60 participantsflagStress Relief forscienceAshwagandha
- Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
Randomized trial137 participantsflagStress Relief forscienceMagnesium
- Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
Non-randomized trial60 participantsflagStress Relief forscienceMagnesium
- Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
Randomized trial45 participantsflagStress Relief forscienceMagnesium
- Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
Randomized trialflagStress Relief forscienceMagnesium
- Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
Randomized trial50 participantsflagTestosterone Support forscienceAshwagandha
- Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
Systematic review32 studies pooledflagTestosterone Support forscienceAshwagandha
- Do "testosterone boosters" really increase serum total testosterone? A systematic review.
Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
Systematic review3 studies pooledflagTestosterone Support forscienceAshwagandha
- Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
Randomized trial40 participantsflagTestosterone Support forscienceAshwagandha
- Biochemical and physiologic consequences of boron deprivation in humans.
Nielsen FH · Environmental health perspectives · 1995
Single-arm trial12 participantsflagTestosterone Support forscienceBoron
- Plasma boron and the effects of boron supplementation in males.
Green NR; Ferrando AA · Environmental health perspectives · 1995
Randomized trial19 participantsflagTestosterone Support forscienceBoron
- Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
Non-randomized trial8 participantsflagTestosterone Support forscienceBoron
- Magnesium and anabolic hormones in older men.
Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
Cohort study399 participantsflagTestosterone Support forscienceMagnesium
- Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
Cross-sectional study313 participantsflagTestosterone Support forscienceMagnesium
- Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
Randomized trial64 participantsflagTestosterone Support forscienceMagnesium
- The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
Meta-analysis1,600 participants25 studies pooledflagTestosterone Support forscienceMagnesium
- Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
Non-randomized trial20 participantsflagTestosterone Support forscienceMagnesium
- Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
Cross-sectional study219 participantsflagTestosterone Support forscienceZinc
- Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
Scoping reviewflagTestosterone Support forscienceZinc
- Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinological and biochemical effects of zinc deficiency.
Prasad AS · Clinics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc
- Clinical, endocrinologic, and biochemical effects of zinc deficiency.
Prasad AS · Special topics in endocrinology and metabolism · 1986
Narrative reviewflagTestosterone Support forscienceZinc