Peptiva + Sleep Support
Peptiva
Peptiva + Sleep Support
4.1
★ ★ ★ ★ ★
(4584 ratings)
Valerian 50 mg
GABA 100 mg
Melatonin 0.75 mg
Score 72.0
A probiotic-enhanced sleep and stress support supplement with PharmaGABA, but features lower doses of melatonin and valerian for a relatively high price.
Quantity: 30 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (30 servings)
Selected goals:
Other goals:
Stress Relief
Mood Support
Sleep Support
Anti-Aging
leaderboard Score 72.0
A probiotic-enhanced sleep and stress support supplement with PharmaGABA, but features lower doses of melatonin and valerian for a relatively high price.
insights Analysis
Peptiva + Sleep Support is formulated to address sleep, stress, and mood, with an additional, less substantiated claim for anti-aging. It combines a low dose of melatonin, a moderate but high-quality form of GABA (PharmaGABA), a very low dose of valerian, and a proprietary probiotic matrix. This blend aims for a comprehensive approach, particularly leveraging the gut-brain axis connection through probiotics for overall well-being, which distinguishes it from many pure sleep aids. The product is popular with over 4500 reviews, indicating a significant user base, though the specific efficacy for all claimed goals can be debated based on individual ingredient dosages and the opacity of the probiotic blend.
- Unique inclusion of a proprietary probiotic matrix for gut-brain axis support, potentially aiding mood and stress.
- Uses PharmaGABA (100mg), a high-quality, bioavailable form of GABA known for promoting relaxation and reducing stress.
- Contains multiple ingredients (Melatonin, Valerian, GABA, Probiotics) targeting sleep and stress relief for a holistic approach.
- High review count (4584) indicates popularity and perceived effectiveness by many users, suggesting it meets a demand.
- Relatively low doses of Melatonin (0.75mg) and Valerian (50mg) compared to many effective standalone or blended alternatives.
- The "Anti-Aging" goal is not strongly supported by the listed ingredients, as there are no direct anti-aging compounds present.
- High price per serving ($1.66) for the ingredient profile and doses, offering less value compared to some potent alternatives.
- The "Proprietary Probiotic Matrix" lacks transparency on specific strains and their individual quantities, making it difficult to fully assess its targeted efficacy for sleep or mood.
- Melatonin can cause drowsiness; it should be taken before bedtime and may impair ability to drive or operate machinery.
- Valerian may interact with sedatives, alcohol, or other CNS depressants, increasing their effects.
- Individuals with compromised immune systems or serious digestive conditions should consult a healthcare professional before taking probiotic supplements.
$49.99($1.66 per serving)
 iHerb | $ 49.99 | |
 Amazon | $ 49.99 |
bolt Effectiveness for goals
Yes, research indicates that lower doses of melatonin, even below 1 mg, can be effective for some individuals, particularly in helping to regulate the body's natural sleep-wake cycle. These doses may assist with sleep onset without causing excessive grogginess. The effectiveness can vary based on individual sensitivity and specific sleep challenges.
Valerian root is believed to exert its calming effects by interacting with the body's GABA system, similar to how benzodiazepines work but in a milder manner. Valerenic acids are thought to be key active compounds that may help increase the availability of GABA in the brain. This action can lead to a reduction in anxiety and promotion of sleep onset and quality.
PharmaGABA is a specific form of GABA that has been studied for its potential to support relaxation and sleep by influencing the nervous system. Some research suggests it may be more effective than other forms of oral GABA in crossing the blood-brain barrier. It aims to calm neural activity, contributing to a sense of tranquility before sleep.
Probiotics contribute to a healthy gut microbiome, which is increasingly recognized for its connection to the brain through the gut-brain axis. A balanced gut can influence mood, stress response, and indirectly, sleep quality. While not a direct sleep aid, supporting gut health with a proprietary probiotic matrix can contribute to overall physiological balance that may foster better sleep.
Combining these ingredients for sleep support is common in many formulations, including Peptiva + Sleep Support. They are generally considered safe together at recommended doses and may offer complementary pathways to improve sleep. However, this combination could potentially increase drowsiness, so it's important to adhere to dosage instructions.
schedule Dosage, timing & forms
Ingredients like melatonin, valerian, and GABA are typically recommended to be taken shortly before bedtime. Melatonin usually works best when taken about 30-60 minutes before sleep, while valerian and GABA can also be taken within this window to align with their relaxation effects.
Yes, even low doses of melatonin, like 0.75mg, can be effective for promoting sleep in some individuals. This is particularly true for those sensitive to its effects or for addressing mild sleep disturbances. The optimal dose can vary widely depending on individual response.
A 50mg dose of valerian is on the lower end compared to many studies and traditional uses, which often suggest doses ranging from 300mg to 600mg for sleep. However, its effectiveness can depend on the specific extract (e.g., Valerenic Acids) and its combination with other ingredients in a formulation.
Research suggests that doses of GABA, including specific forms like PharmaGABA, in the range of 100mg to 200mg can contribute to relaxation and improve sleep quality in some individuals. The bioavailability and effectiveness can vary based on the specific GABA form and individual response.
For optimal effectiveness, sleep-support ingredients like melatonin and valerian are typically taken before bed. Probiotics are often recommended to be taken with food or at a consistent time each day to maximize survival and colonization. Taking them together before bed should generally not pose an issue, provided the probiotic strains can survive stomach acid.
health_and_safety Safety & interactions
Yes, melatonin, valerian, and GABA can all have sedative effects individually. Combining them may result in additive drowsiness or impaired coordination, especially when first starting use. It is advisable to avoid operating heavy machinery or driving until you understand how these ingredients affect you.
Melatonin, valerian, and GABA can potentially interact with certain medications, including sedatives, antidepressants, blood thinners, and immunosuppressants. These interactions could either increase medication effects or reduce their efficacy. It is recommended to consult a healthcare professional before use if you are taking any prescription medications.
Common side effects of valerian can include dizziness, headache, gastrointestinal upset, and daytime drowsiness. These effects are usually mild and temporary. It is generally not recommended to stop valerian suddenly after long-term use, as withdrawal symptoms might occur in rare cases.
Potential side effects of melatonin include drowsiness, dizziness, headache, and nausea. It can also cause vivid dreams or mild abdominal cramps. These effects are typically mild and transient, especially with lower doses.
There is insufficient reliable evidence regarding the safety of melatonin, valerian, and GABA for use during pregnancy or breastfeeding. For this reason, it is generally advised to avoid their use. Consult with a healthcare provider before taking any supplements if you are pregnant or breastfeeding.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Proprietary Probiotic Matrix | 64 mg |
Gamma-Aminobutyric Acid | 100 mg |
Valerian | 50 mg |
Melatonin | 0.75 mg |
Categories
GABA 85.0
Peptiva includes 100mg of PharmaGABA, which is a patented and highly regarded form of Gamma-Aminobutyric Acid known for its superior bioavailability and effectiveness in promoting relaxation and reducing stress. This is a moderate yet impactful dose, contributing effectively to the product's calming and mood-supporting goals.
Melatonin 65.0
The product contains 0.75mg of Melatonin, which is a very low physiological dose. While this can be effective for some individuals, particularly for sleep onset without next-day grogginess, it is significantly lower than the 3mg or 5mg doses found in many popular melatonin supplements, potentially limiting its effectiveness for those with more pronounced sleep issues.
Valerian 60.0
The product contains 50mg of Valerian (as Valerenic Acids), which is a very low dose compared to scientific studies and many other supplements that typically use 300-600mg for effective sleep and anxiety support. While standardized, this low concentration may limit its perceived efficacy for many users seeking stronger valerian benefits.
Goals
Stress Relief 75.0
PharmaGABA (100mg) and Valerian (50mg) are known for their anxiolytic and calming properties, directly contributing to stress relief. The inclusion of the proprietary probiotic matrix offers an innovative approach, as emerging research on the gut-brain axis suggests that a healthy microbiome can positively influence stress responses, providing a unique, albeit indirect, benefit.
Mood Support 75.0
Similar to stress relief, the PharmaGABA and Valerian contribute to a calmer state, which is beneficial for mood. The probiotic matrix is a key differentiator, as a healthy gut microbiome has been linked to improved mood and reduced symptoms of anxiety and depression through its influence on neurotransmitter production and overall gut-brain communication, making it a unique element for mood support.
Sleep Support 70.0
The product includes Melatonin, Valerian, and PharmaGABA, all recognized for promoting sleep. While the doses of Melatonin (0.75mg) and Valerian (50mg) are lower than typically recommended for strong acute effects, the PharmaGABA at 100mg is a good dose and form for calming, and the probiotic matrix may indirectly support sleep quality through the gut-brain axis. Its effectiveness may vary, particularly for individuals needing higher doses of traditional sleep aids.