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Omega-3 2100 with Vitamin D Vanilla Flavor

Oceanblue Professional
4.7
★ ★ ★ ★ ★
(202 ratings)
Omega-3 2100 mg
Product Image
Score71
High-total omega-3 plus vitamin D offers useful nutritional support. Higher cost and incomplete fatty-acid quality details hold it back.
How scoring works
Quantity:60 Softgel(s) • (30 servings)
Goals:
Joint Health
Skin Health

Score 71

High-total omega-3 plus vitamin D offers useful nutritional support. Higher cost and incomplete fatty-acid quality details hold it back.
How scoring works
$25.49($0.84 per serving)
Vitacost
$ 29.09
iHerb
$ 28.04
iHerb
$ 25.49
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Analysis

The serving supplies 2,100 mg total omega-3 ethyl esters and 50 mcg vitamin D3. The combination supports fatty-acid nutrition with added bone and muscle relevance.

Skin and joint inflammatory pathways receive meaningful total omega-3 depth, but EPA and DHA are not separated. The product does not directly raise metabolic rate or provide cartilage ingredients.

Thirty servings and a higher cost reduce value compared with larger variants. Ethyl ester absorption is meal dependent, while antioxidant and purity details are absent.

Who is it for
  • Adults seeking concentrated omega-3 with vitamin D
  • People wanting a 30-serving bottle
  • Users willing to take it with food
Best for
  • Omega-3 plus vitamin D supplementation
  • Secondary joint support
  • General fatty-acid intake

Pros

  • Provides 2,100 mg total omega-3
  • Includes 50 mcg vitamin D3
  • Concentrated softgel serving
  • Form is disclosed

Cons

  • EPA and DHA are not separated
  • Ethyl ester form requires food
  • No antioxidant details
  • Higher serving cost

Warnings

  • Take ethyl ester omega-3 with a fat-containing meal
  • High-dose omega-3 may increase bleeding tendency
  • Count total vitamin D intake across supplements

Nutrient quality

79 High impact

Concentrated omega-3 and useful vitamin D provide strong active depth. The ethyl-ester form and missing EPA, DHA, source, antioxidant, and purity details reduce quality confidence.

Ingredient transparency

66 High impact

Listed active ingredients carry amounts and no proprietary blend hides a supplied dose. Missing fatty-acid detail, complete directions, or an excipient list keeps disclosure incomplete.

Customer satisfaction

62 Moderate impact

The supplied average rating is strong and the review volume is limited. Specific comments are absent, so repeated complaints and purpose-specific experiences cannot be assessed.

Value for money

76 High impact

Concentrated active delivery supports useful serving value. Incomplete fatty-acid, antioxidant, and sourcing detail weakens the category comparison.

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Goals

Joint Health
Joint Health
Impact
High effect
B Goal FitC+ Strength of SupportC- CoverageA Formula Quality
Omega-3 · 2100 mg

Omega-3 fatty acids may help inflammatory joint discomfort, giving the product a direct but narrow joint-health role. The label lists 2100 mg total omega-3 with vitamin D3 for bone and muscle support.

EPA and DHA amounts are not separated, so the clinically relevant anti-inflammatory dose cannot be confirmed, and the ethyl-ester form offers only moderate absorption. The formula does not provide cartilage building blocks or joint-lubricating compounds.

Study evidence
Omega-3 Supportive 40 studies
Vitamin D Supportive 111 studies
Skin Health
Skin Health
Impact
High effect
C+ Goal FitC+ Strength of SupportC- CoverageB+ Formula Quality
Omega-3 · 2100 mg

Omega-3 fatty acids may support skin barrier lipids and inflammatory balance, while vitamin D adds limited general skin support. The total omega-3 amount is substantial.

EPA and DHA are not listed separately, and the ethyl ester form has only moderate absorption potential. No collagen, ceramide, or dedicated photo-protective active is included.

Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per serving
Calories
25 Calorie(s)
Total Fat
2.5 Gram(s)
Cholesterol
10 mg
Protein
1 Gram(s)
Vitamin D3 (Cholecalciferol)
 50 mcg
Total Omega-3 Fatty Acids Ethyl Esters
2100 mg
Adults 18–50
Report overview
Omega-3 · 2100 mg OverallScore28
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The omega-3s are explicitly ethyl esters, which offer moderate rather than high absorption potential. EPA and DHA are not separated, and neither antioxidant protection nor independent purity verification is disclosed. Value per active gram cannot be confirmed from total omega-3 alone.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Omega-3 Fatty Acids Intake on Lipid Metabolism and Plaque Volume in Patients With Coronary Heart Disease: A Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials.
    Zhang C; Xie Y; Zhou J; Zhang C; Xiang Q; Zhong Y; Xiao J; Feng J; Liao B; Chen X; Deng L · Food science & nutrition · 2025
    Meta-analysis2,061 participants23 studies pooledMetabolism Boost forOmega-3
  2. Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
    Pahor M; Anton SD; Beavers DP; Cauley JA; Fielding RA; Kritchevsky SB; Leeuwenburgh C; Lewis KH; Liu CK; Lovato LC; Lu J; Manini TM; McDermott MM; Miller ME; Newman AB; Radziszewska B; Stowe CL; Tracy RP; Walkup MP; Wu SS; Ambrosius WT · The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Randomized trial289 participantsJoint Health forOmega-3
  3. The Effects of α-Linolenic Acid Intake on Skin and Blood Vessel Health and Subjective Fatigue in Middle-Aged Japanese Females: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparative Trial.
    Ando N; Nosaka N; Arai C; Kato K · The Journal of nutrition · 2025
    Randomized trial120 participantsSkin Health forOmega-3
  4. Omega-3 polyunsaturated fatty acids and the treatment of rheumatoid arthritis: a meta-analysis.
    Lee YH; Bae SC; Song GG · Archives of medical research · 2013
    Meta-analysis10 studies pooledJoint Health forOmega-3
  5. Dietary supplementation with very long-chain n-3 fatty acids in patients with atopic dermatitis. A double-blind, multicentre study.
    Søyland E; Funk J; Rajka G; Sandberg M; Thune P; Rustad L; Helland S; Middelfart K; Odu S; Falk ES · The British journal of dermatology · 1994
    Randomized trial145 participantsSkin Health forOmega-3
  6. The association of organophosphate flame retardants (OPFRs) exposure on omega-3 fatty acids metabolism: evidence derived from the United States general population.
    Hsu TH; Pan HY; Tsai KF; Kung CT; Huang WT; You HL; Li SH; Wang CC; Lee WC; Cheng FJ · Toxicology research · 2025
    Cross-sectional study1,350 participantsMetabolism Boost forOmega-3
  7. Prenatal Omega-3 Supplementation and Eczema Risk among Offspring at Age 36 Months.
    Berman D; Clinton C; Limb R; Somers EC; Romero V; Mozurkewich E · Insights in allergy, asthma & bronchitis · 2020
    Randomized trial84 participantsSkin Health forOmega-3
  8. Dietary fats and prevention of type 2 diabetes.
    Risérus U; Willett WC; Hu FB · Progress in lipid research · 2010
    Narrative reviewMetabolism Boost forOmega-3
  9. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
    Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
    Randomized trial235 participantsJoint Health forOmega-3
  10. Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
    Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
    Meta-analysis331 participants6 studies pooledMetabolism Boost forOmega-3
  11. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
    Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
    Meta-analysis1,018 participants18 studies pooledJoint Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
    Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
    Randomized trial43 participantsJoint Health forOmega-3
  14. Fish oil supplementation and insulin sensitivity: a systematic review and meta-analysis.
    Gao H; Geng T; Huang T; Zhao Q · Lipids in health and disease · 2018
    Meta-analysis672 participants17 studies pooledMetabolism Boost forOmega-3
  15. Randomized controlled trial of oral omega-3 PUFA in solar-simulated radiation-induced suppression of human cutaneous immune responses.
    Pilkington SM; Massey KA; Bennett SP; Al-Aasswad NM; Roshdy K; Gibbs NK; Friedmann PS; Nicolaou A; Rhodes LE · The American journal of clinical nutrition · 2013
    Randomized trial79 participantsSkin Health forOmega-3
  16. Improvement in Glycolipid Metabolism Parameters After Supplementing Fish Oil-Derived Omega-3 Fatty Acids Is Associated with Gut Microbiota and Lipid Metabolites in Type 2 Diabetes Mellitus.
    Xia J; Yin S; Yu J; Wang J; Jin X; Wang Y; Liu H; Sun G · Nutrients · 2024
    Randomized trial110 participantsMetabolism Boost forOmega-3
  17. Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
    Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
    Meta-analysis1,420 participants30 studies pooledJoint Health forOmega-3
  18. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  19. Fish oil in knee osteoarthritis: a randomised clinical trial of low dose versus high dose.
    Hill CL; March LM; Aitken D; Lester SE; Battersby R; Hynes K; Fedorova T; Proudman SM; James M; Cleland LG; Jones G · Annals of the rheumatic diseases · 2016
    Randomized trial202 participantsJoint Health forOmega-3
  20. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  21. Oils Rich in α-Linolenic Acid or Docosahexaenoic Acid Have Distinct Effects on Plasma Oxylipin and Adiponectin Concentrations and on Monocyte Bioenergetics in Women with Obesity.
    Pauls SD; Rodway LR; Sidhu KK; Winter T; Sidhu N; Aukema HM; Zahradka P; Taylor CG · The Journal of nutrition · 2022
    Randomized trialMetabolism Boost forOmega-3
  22. Dietary Long-Chain n-3 Fatty Acid Intake and Arthritis Risk in the Women's Health Initiative.
    Krok-Schoen JL; Brasky TM; Hunt RP; Rohan TE; Baker TA; Li W; Carbone L; Mackey RH; Snetselaar L; Lustberg MB; Neuhouser ML · Journal of the Academy of Nutrition and Dietetics · 2019
    Cohort study80,551 participantsJoint Health forOmega-3
  23. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  24. The consumption of omega-3 polyunsaturated fatty acids improves clinical outcomes and prognosis in pancreatic cancer patients: a systematic evaluation.
    Ma YJ; Yu J; Xiao J; Cao BW · Nutrition and cancer · 2015
    Meta-analysis11 studies pooledMetabolism Boost forOmega-3
  25. Effect of long-term omega-3 supplementation and a lifestyle multidomain intervention on intrinsic capacity among community-dwelling older adults: Secondary analysis of a randomized, placebo-controlled trial (MAPT study).
    Giudici KV; de Souto Barreto P; Beard J; Cantet C; Araujo de Carvalho I; Rolland Y; Vellas B; MAPT DSA group · Maturitas · 2020
    Randomized trial1,445 participantsJoint Health forOmega-3
  26. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3
  27. Effect of isotretinoin and omega-3 fatty acid combination on lipid metabolism in patients with acne vulgaris: a randomized controlled trial.
    Du P; Huang Y; Hu J; Xiong X; Deng Y · Lipids in health and disease · 2026
    Randomized trial66 participantsMetabolism Boost forOmega-3
  28. Beneficial effect of n-3 polyunsaturated fatty acids on inflammation and analgesic use in psoriatic arthritis: a randomized, double blind, placebo-controlled trial.
    Kristensen S; Schmidt EB; Schlemmer A; Rasmussen C; Johansen MB; Christensen JH · Scandinavian journal of rheumatology · 2018
    Randomized trial145 participantsJoint Health forOmega-3
  29. Allergic disease in infants up to 2 years of age in relation to plasma omega-3 fatty acids and maternal fish oil supplementation in pregnancy and lactation.
    Furuhjelm C; Warstedt K; Fagerås M; Fälth-Magnusson K; Larsson J; Fredriksson M; Duchén K · Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2011
    Randomized trial145 participantsSkin Health forOmega-3
  30. Supplementation with n-3 fatty acids reduces triglycerides but increases PAI-1 in non-insulin-dependent diabetes mellitus.
    Boberg M; Pollare T; Siegbahn A; Vessby B · European journal of clinical investigation · 1993
    Randomized trial14 participantsMetabolism Boost forOmega-3
  31. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
    Goldberg RJ; Katz J · Pain · 2007
    Meta-analysis17 studies pooledJoint Health forOmega-3
  32. Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
    Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
    Randomized trial413 participantsJoint Health forVitamin D
  33. Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
    Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
    Meta-analysis146,054 participants10 studies pooledJoint Health forVitamin D
  34. Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
    Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
    Meta-analysis1,599 participants6 studies pooledJoint Health forVitamin D
  35. Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
    Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
    Randomized trial413 participantsJoint Health forVitamin D
  36. The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
    Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
    Meta-analysis11,890 participants28 studies pooledJoint Health forVitamin D