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Breathe-X Allergy & Sinus Support

LifeSeasons
4.5
★ ★ ★ ★ ★
(1070 ratings)
Vitamin C 500 mg
Astragalus 100 mg
Bromelain 250 mg
Stinging Nettle 100 mg
Flavonoid (mixture) 200 mg
Product Image
Score70
A high-quercetin allergy-support blend with meaningful vitamin C and bromelain, limited by missing potency details, high cost, and important bleeding-risk considerations.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Anti-Inflammatory Support
General Health
Immunity

Score 70

A high-quercetin allergy-support blend with meaningful vitamin C and bromelain, limited by missing potency details, high cost, and important bleeding-risk considerations.
How scoring works
$39.99($1.33 per serving)
iHerb
$ 39.99
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Analysis

Quercetin leads the formula at a substantial amount, with vitamin C, bromelain, and citrus bioflavonoids adding related antioxidant and inflammatory-signaling support. The combination is better aligned with seasonal allergy and sinus needs than with broad daily wellness.

Amounts are disclosed, but bromelain potency cannot be judged without enzyme activity units. Nettle and astragalus also lack the plant-part, extraction, or marker information needed to understand their practical contribution.

The product fits adults seeking a concentrated quercetin-based blend and who understand the bromelain precautions. It is a poor fit for testosterone support and offers only indirect value for vision, skin, or digestive health.

Who is it for
  • Adults seeking quercetin-centered seasonal support
  • Users wanting antioxidant and sinus-focused ingredients
  • People not using medicines that conflict with bromelain
Best for
  • Seasonal allergy support
  • Quercetin supplementation
  • Antioxidant and inflammatory-balance support

Pros

  • Substantial quercetin amount
  • Meaningful vitamin C and bromelain weights
  • Clearly stated active amounts

Cons

  • Bromelain activity units are missing
  • Nettle and astragalus lack potency detail
  • High serving cost

Warnings

  • Bromelain may increase bleeding risk with anticoagulant or antiplatelet medicines
  • Stop bromelain before surgery only according to the surgical team's instructions
  • Avoid if allergic to pineapple because bromelain is pineapple-derived
  • The ascorbic acid amount may irritate an acid-sensitive stomach

Nutrient quality

81 Highest impact

Quercetin dihydrate is clear, while ascorbic acid is unbuffered and magnesium oxide absorbs poorly. Quercetin, vitamin C, and bromelain are substantial, though bromelain activity is not disclosed.

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Ingredient transparency

75 High impact

All ingredient weights are shown, but bromelain activity and botanical marker yields are missing. The supplied data does not include a complete inactive ingredient list.

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Customer satisfaction

66 High impact

The aggregate satisfaction measure is strong enough to support a favorable first impression. Missing feedback themes leave repeat complaints and purpose fit uncertain despite adequate volume.

.

Value for money

51 Moderate impact

The premium price is only partly justified by substantial quercetin and bromelain weights. Each serving is costly despite useful core doses.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A- Goal FitB Strength of SupportA- CoverageB+ Formula Quality
Vitamin C · 500 mg

Quercetin, bromelain, vitamin C, bioflavonoids, nettle, and astragalus provide broad antioxidant and inflammatory-signaling support. Quercetin and bromelain are supplied at substantial weights, making them more than label extras.

Bromelain activity units are not disclosed, and nettle lacks plant-part or extract details, so two key potencies remain uncertain. Bromelain may increase bleeding risk with anticoagulant or antiplatelet medicines, especially around surgery.

Study evidence
Bromelain Supportive 12 studies
Stinging Nettle Supportive 5 studies
Vitamin C Supportive 50 studies
General Health
General Health
Impact
High effect
C+ Goal FitB Strength of SupportC+ CoverageB Formula Quality
Magnesium · 30 mgVitamin C · 500 mg

Vitamin C and quercetin provide antioxidant support, but the allergy-focused formula is narrower than a daily wellness product. Vitamin C is well established, while evidence for the botanical combination is more situational and symptom focused.

Vitamin C at 500 mg, quercetin at 1000 mg, and bromelain at 250 mg are material rather than token additions. Amounts are clear, but magnesium oxide is poorly absorbed and bromelain enzyme activity is not disclosed.

Study evidence
Bromelain Supportive 11 studies
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Immunity
Immunity
Impact
High effect
B+ Goal FitC- Strength of SupportC+ CoverageB Formula Quality
Magnesium · 30 mgVitamin C · 500 mg

Astragalus, Vitamin C, and Bromelain provide relevant support for immunity. Vitamin C is a foundational and direct-acting nutrient for immune cell function and antioxidant protection.

The astragalus root extract offers a modest supporting amount within a broad allergy and sinus formula. The high cost makes it poor value as an astragalus source, and bromelain may increase bleeding risk with anticoagulant or antiplatelet medicines.

Study evidence
Astragalus Supportive 16 studies
Bromelain Not classified 1 study
Vitamin C Supportive 53 studies
Digestive Health
Digestive Health
Impact
Moderate effect
C- Goal FitB- Strength of SupportD+ CoverageD+ Formula Quality
Bromelain · 250 mgMagnesium · 30 mg

Bromelain may aid protein digestion when taken with meals, while quercetin and vitamin C add antioxidant support. The wider formula is designed for allergy and sinus concerns rather than a broad digestive goal.

The bromelain amount is substantial, but enzyme activity units are missing and meal-timing guidance is not provided. Bromelain may raise bleeding risk with anticoagulants and can trigger reactions in people with pineapple allergy.

Study evidence
Bromelain Supportive 2 studies
Skin Health
Skin Health
Impact
Moderate effect
C- Goal FitB- Strength of SupportC CoverageD Formula Quality
Vitamin C · 500 mg

Vitamin C directly supports collagen synthesis, while quercetin and bioflavonoids add antioxidant defense. The formula is designed for allergy support and lacks a structural peptide or hydration active.

Vitamin C and quercetin are supplied in substantial, clearly disclosed amounts. Plain ascorbic acid and the absence of skin-specific cofactor pairing keep the product from being a strong beauty formula.

Study evidence
Vitamin C Supportive 53 studies
Vision Support
Macular and Blue Light Defense
Vision Support
Impact
Moderate effect
F Goal FitB Strength of SupportD CoverageC+ Formula Quality
Vitamin C · 500 mg

Vitamin C, quercetin, and citrus bioflavonoids provide a substantial antioxidant stack with indirect ocular relevance. The allergy-focused formula lacks macular carotenoids, zinc, copper, vitamin E, and DHA.

Quercetin and vitamin C amounts are strong and clearly stated. Astragalus, nettle, and bromelain serve allergy support rather than distinct vision pathways.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 500 mg
Magnesium (Magnesium Oxide)
 30 mg
Quercetin (Quercetin Dihydrate)
 1000 mg
Bromelain (Ananas comosus)
 250 mg
Citrus Bioflavonoids (Flavones)
 200 mg
Astragalus root extract
100 mg
Nettle
100 mg
Gluten Free Adults 18–50 Dairy Free Vegetarian
Report overview
Vitamin C (Ascorbic Acid) · 500 mg OverallScore52
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

The 500 mg Vitamin C dose is well targeted, but plain unbuffered ascorbic acid offers basic delivery. Large amounts of quercetin and other botanicals position the formula for a broader purpose rather than focused Vitamin C use. The cost per gram is very high for the form provided.

View ingredientView products
Astragalus · 100 mg OverallScore49
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

The astragalus root extract offers a modest supporting amount within a broad allergy and sinus formula. Root is clearly named, but the species, extract ratio, active markers, and organic status are not provided. The high cost makes it poor value as an astragalus source, and bromelain may increase bleeding risk with anticoagulant or antiplatelet medicines.

View ingredientView products
Bromelain (Ananas comosus) · 250 mg OverallScore46
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyD+ Value

The allergy and sinus formula provides a substantial bromelain amount alongside high-dose quercetin, but enzyme activity is not disclosed. A standard capsule offers limited systemic protection, and use timing is not stated. The costly serving gains some value from the substantial quercetin component.

View ingredientView products
Loading alternative details
69 Performance

Sinus Adult Sinus Support

Redd Remedies
<p>Quercetin, NAC, bromelain, vitamin C, citrus flavonoids, and nettle preserve the closest sinus-focused profile while adding NAC. Quercetin and bromelain amounts are lower than in the original, and bromelain activity is still not disclosed.</p>
86 Performance

C

Swanson
<p>Fully buffered calcium ascorbate provides a focused, stomach-friendly vitamin C alternative without the original’s under-characterized botanicals and magnesium oxide. It is not a full allergy formula because quercetin, bromelain, and nettle are absent.</p>
86 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
<p>A substantial buffered vitamin C amount and citrus bioflavonoids improve core nutrient form quality and simplify the label. The trade-off is loss of quercetin, bromelain, astragalus, and nettle for direct allergy support.</p>
84 Budget

Ester-C 500 mg With Citrus Bioflavoinds

American Health
<p>Buffered vitamin C and citrus bioflavonoids provide a far lower-cost daily antioxidant base than the original. The switch removes quercetin, bromelain, astragalus, and nettle, so it is less targeted to allergy and sinus support.</p>
84 Budget

Ester-C 24 Hour Immune Support 1000 mg

NatureSmart
<p>A substantial buffered vitamin C amount with citrus bioflavonoids offers much better everyday value and expected stomach comfort. It does not replace the original’s high-dose quercetin or its bromelain and botanical ingredients.</p>
83 Budget

Reacta C 500 mg

Solaray
<p>Buffered calcium ascorbate and citrus concentrate create an inexpensive, focused alternative for the vitamin C portion of the original. A vaguely named support base reduces transparency, and the formula gives up the allergy-focused quercetin, bromelain, and nettle.</p>
86 Value

Buffered Vitamin C + Citrus Bioflavonoids

Jarrow Formulas
<p>Buffered vitamin C and a meaningful bioflavonoid amount provide strong everyday antioxidant value with a simple label. It costs less to use but does not cover the original’s quercetin, bromelain, astragalus, or nettle.</p>
83 Value

Easy-C 500 mg

Natrol
<p>Calcium ascorbate, ascorbyl palmitate, and citrus bioflavonoids create a broad vitamin C base with a long supply. Repeated bioflavonoid entries create some ambiguity, and the formula is less allergy-specific than the original.</p>
84 Value

Buffered Vitamin C 1000 mg

Country Life
<p>A substantial vitamin C amount with partial mineral buffering and lemon bioflavonoids offers better serving value than the original. Magnesium is still supplied as oxide, and the option omits quercetin, bromelain, astragalus, and nettle.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  2. Effects of vitamin C on oxidative stress, inflammation, muscle soreness, and strength following acute exercise: meta-analyses of randomized clinical trials.
    Righi NC; Schuch FB; De Nardi AT; Pippi CM; de Almeida Righi G; Puntel GO; da Silva AMV; Signori LU · European journal of nutrition · 2021
    Meta-analysis313 participants18 studies pooledAnti-Inflammatory Support forVitamin C
  3. A High Vitamin C Micronutrient Supplement Is Unable to Attenuate Inflammation in People with Metabolic Syndrome but May Improve Metabolic Health Indices: A Randomised Controlled Trial.
    Vlasiuk E; Zawari M; Whitehead R; Williman J; Carr AC · Antioxidants (Basel, Switzerland) · 2024
    Randomized trial72 participantsAnti-Inflammatory Support forVitamin C
  4. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support General Health Immunity forBromelain
  5. Is bromelain an effective drug for the control of pain and inflammation associated with impacted third molar surgery? Systematic review and meta-analysis.
    de A C Almeida R; de Sousa Lima FCM; do E Vasconcelos BC · International journal of oral and maxillofacial surgery · 2019
    Meta-analysis252 participants5 studies pooledAnti-Inflammatory Support forBromelain
  6. Effect of Oral Administration of Bromelain on Postoperative Discomfort After Third Molar Surgery.
    Ghensi P; Cucchi A; Creminelli L; Tomasi C; Zavan B; Maiorana C · The Journal of craniofacial surgery · 2018
    Randomized trial84 participantsAnti-Inflammatory Support forBromelain
  7. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  8. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support General Health forBromelain
  9. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  10. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  11. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  12. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  13. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  14. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  15. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  16. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  17. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  18. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  19. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  20. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  21. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  22. Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trial.
    Majid OW; Al-Mashhadani BA · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2014
    Randomized trial45 participantsGeneral Health forBromelain
  23. Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.
    Shoham Y; Gasteratos K; Singer AJ; Krieger Y; Silberstein E; Goverman J · International wound journal · 2023
    Systematic review34 studies pooledGeneral Health forBromelain
  24. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.
    Walker AF; Bundy R; Hicks SM; Middleton RW · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial77 participantsGeneral Health forBromelain
  25. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  26. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  27. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  28. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  29. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  30. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  31. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  32. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  33. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  34. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  35. Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies.
    Sun T; Zhao R; Zhang Y; Li D; Shan X; Tang X; Zheng Y · Frontiers in pharmacology · 2025
    Meta-analysis776 participants9 studies pooledImmunity forAstragalus
  36. [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis].
    Su L; Mao JC; Gu JH · Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine · 2008
    Randomized trial43 participantsImmunity forAstragalus
  37. Astragalus mongholicus (Fisch.) Bge Improves Peripheral Treg Cell Immunity Imbalance in the Children With Viral Myocarditis by Reducing the Levels of miR-146b and miR-155.
    Zhang Z; Dai X; Qi J; Ao Y; Yang C; Li Y · Frontiers in pediatrics · 2020
    Randomized trial68 participantsImmunity forAstragalus
  38. [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor].
    Duan P; Wang ZM · Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine · 2003
    Randomized trial120 participantsImmunity forAstragalus
  39. [Modulatory effect of Astragalus membranaceus on Th1/Th2 cytokine in patients with herpes simplex keratitis].
    Mao SP; Cheng KL; Zhou YF · Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine · 2004
    Randomized trial168 participantsImmunity forAstragalus
  40. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  41. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  42. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  43. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  44. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  45. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  46. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  47. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  48. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  49. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  50. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  51. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  52. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  53. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  54. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C