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Nordic CoQ10 Ubiquinol 100 mg

Nordic Naturals
4.7
★ ★ ★ ★ ★
(693 ratings)
Coenzyme Q-10 100 mg
Product Image
Score78
A high-quality 100 mg ubiquinol softgel with clear disclosure and sensible delivery. Premium cost is the decisive drawback.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Heart Health
Energy
Cardiovascular Support
Anti-Aging
Anti-Inflammatory Support
Metabolism Boost

Score 78

A high-quality 100 mg ubiquinol softgel with clear disclosure and sensible delivery. Premium cost is the decisive drawback.
How scoring works
$54.36($0.90 per serving)
Pure Formulas
$ 54.36
iHerb
$ 54.36
Vitacost
$ 55.25
Amazon
$ 54.36
Daily Vita
$ 54.36
Report prices

Analysis

One hundred milligrams of ubiquinol supplies the reduced CoQ10 form at a useful maintenance amount. Softgel delivery complements its fat-soluble nature and supports the absorption-focused formulation.

The active form and amount are clearly disclosed, leaving little uncertainty about the core ingredient. The formula remains a simple single-active product without additional mitochondrial pathways.

It suits buyers who place brand or formulation preference above price. Value-conscious users can obtain similarly defined ubiquinol and softgel delivery in more economical products.

Who is it for
  • Adults prioritizing reduced ubiquinol
  • Softgel users with absorption concerns
  • Buyers comfortable paying a premium
Best for
  • Absorption-focused maintenance
  • Routine cardiovascular support
  • Clearly labeled ubiquinol use

Pros

  • Uses reduced ubiquinol
  • Useful 100 mg amount
  • Softgel supports absorption
  • Clear active disclosure

Cons

  • High recurring cost
  • Weak value versus comparable ubiquinol products
  • Single-active design
  • No additional mitochondrial cofactors

Warnings

  • Ubiquinol may reduce the anticoagulant effect of warfarin; prescriber monitoring may be needed
  • CoQ10 may add to blood-pressure-lowering medicines and contribute to dizziness in sensitive users
  • The 100 mg amount may cause mild digestive upset in some users

Nutrient quality

95 Highest impact

Ubiquinol in a softgel is a well-regarded form and delivery combination. The 100 mg ubiquinol serving is meaningful for routine use.

Ingredient transparency

85 Highest impact

Active amounts are disclosed and no proprietary blend hides them. Daily directions and the complete inactive-ingredient list are not supplied.

Customer satisfaction

67 High impact

The supplied average is strong and the review pool is substantial. No specific feedback is provided to judge recurring complaints or purpose fit.

Value for money

59 Moderate impact

Preferred-form ubiquinol supports high formula quality. Serving cost is high compared with similar ubiquinol products.

Report analysis

Goals

Heart Health
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports cardiac cellular energy and antioxidant defense in a readily absorbed molecular form. The softgel format is especially appropriate for this fat-soluble active.

The clearly stated amount is well aligned with common daily use and delivered in one unit. The focused formula is particularly relevant for older adults or people whose statin therapy has lowered CoQ10 status.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Energy
Impact
Highest effect
A- Goal FitA+ Strength of SupportD+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial electron transport and ATP production, making it a focused option for cellular energy. The 100 mg amount is well supported, and softgel delivery suits this fat-soluble compound.

The formula does not address alertness or stress resilience, but it provides strong depth in one relevant pathway. Its single-ingredient design is clear and free of unnecessary additions.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Cardiovascular Support
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports heart-muscle energy production and antioxidant protection. The 100 mg amount is meaningful for general cardiovascular support and is delivered in the more readily absorbed reduced form.

Softgel delivery further supports absorption of this fat-soluble compound. The streamlined formula has strong depth for cardiac energy but does not add lipid, nitric-oxide, or rhythm support.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Anti-Aging
Impact
Highest effect
A- Goal FitA+ Strength of SupportD+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy in a form that is generally easier to absorb. The softgel and clearly stated amount provide a strong delivery and disclosure combination.

The product is best understood as deep support for one aging-related pathway rather than a complete longevity formula. No secondary actives address inflammation, structural maintenance, or glycation.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Anti-Inflammatory Support
Impact
High effect
B Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial antioxidant defense and may help reduce oxidative signals linked to inflammation. The 100 mg amount falls within a commonly used supplemental range.

Ubiquinol is the better-absorbed reduced form, and softgel delivery suits this fat-soluble ingredient. The focused formula has good depth in one pathway but does not address inflammatory enzymes, immune nutrients, or pro-resolving fatty acids.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Metabolism Boost
Impact
High effect
B Goal FitA Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial electron transport, a central step in cellular energy production. The disclosed amount provides useful depth, although evidence for raising whole-body metabolic rate is less direct.

The single-active design is transparent and free from label padding. Coverage remains narrow because thermogenesis, glycemic control, thyroid support, and fatty-acid transport are not addressed.

Study evidence
Coenzyme Q-10 Disputed 11 studies

Ingredients

IngredientAmount per serving
Ubiquinol
100 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 · 100 mg OverallScore84
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Ubiquinol is the reduced form and is generally easier to absorb. Softgel delivery supports absorption of this fat-soluble ingredient. The clearly stated amount aligns well with commonly used higher-dose ranges, but the high serving cost weakens its value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  3. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  4. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  5. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  6. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  7. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  8. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  9. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  10. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  12. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  13. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  14. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  15. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  16. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  17. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  18. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  19. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  20. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  21. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  22. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  23. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  24. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  25. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  26. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  27. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  28. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10