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Sleep 'n Restore

Natrol
4.2
★ ★ ★ ★ ★
(782 ratings)
Valerian 100 mg
Melatonin 3 mg
Glutamine 800 mg
Product Image
Score75
A convenient 3 mg melatonin tablet offers direct sleep-onset support at good value. Valerian is modest and the extra nutrients add little nighttime relevance.
How scoring works
Quantity:20 Tablet(s) • (20 servings)
Goals:
Sleep Support
Stress Relief

Score 75

A convenient 3 mg melatonin tablet offers direct sleep-onset support at good value. Valerian is modest and the extra nutrients add little nighttime relevance.
How scoring works
$5.99($0.29 per serving)
iHerb
$ 5.99
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Analysis

Melatonin at 3 mg provides direct support for sleep timing and onset. Valerian extract is limited to 100 mg and has no disclosed active-marker or concentration details.

Glutamine at 800 mg, vitamin E, calcium, and grape seed make the tablet look broader but do not deepen its sleep mechanism. All amounts are clearly disclosed, which makes the formula easy to assess.

The one-tablet serving and favorable value are practical strengths. It fits occasional melatonin use better than users specifically seeking a substantial valerian or stress-relief formula.

Who is it for
  • Adults seeking nighttime sleep support
  • People who want several calming pathways in one formula
  • Users comfortable with a 3 mg melatonin amount
Best for
  • Bedtime relaxation
  • Sleep-onset support
  • Occasional melatonin-based sleep support

Pros

  • Provides 3 mg melatonin
  • Uses one tablet per serving
  • Clearly lists every active amount
  • Offers favorable value

Cons

  • Valerian is lightly dosed
  • Valerian potency is not standardized
  • Glutamine is not a meaningful sleep active
  • Several nutrients dilute the formula’s focus

Warnings

  • Melatonin may cause next-day drowsiness, especially when sleep time is short.
  • Melatonin and valerian can add to alcohol, sedative, or sleep-medicine effects.
  • Do not drive or perform alertness-dependent tasks after taking the tablet.

Nutrient quality

70 High impact

Natural vitamin E is a useful form, but valerian lacks concentration and active-marker details; melatonin is meaningfully dosed, while valerian and glutamine are modest. The formula avoids a clear dose excess, though melatonin and valerian may add to drowsiness; the main sleep ingredients fit the purpose, but glutamine and antioxidant nutrients are peripheral; several additions contribute little direct sleep support.

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Ingredient transparency

76 High impact

Every listed active has a specific amount; no proprietary blend hides key doses. Most nutrients are specifically named, while the valerian extract remains technically vague; serving directions and inactive ingredients are not included in the supplied details.

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Customer satisfaction

68 High impact

The supplied aggregate average is only moderate, and no individual feedback is available; the large rating sample improves confidence in the aggregate average, but no individual feedback is supplied. Detailed feedback is absent, so repeated complaints cannot be assessed; real-world fit with the intended purpose remains uncertain.

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Value for money

86 Highest impact

Basic quality is appropriate for a low-cost sleep formula; the serving is economical for melatonin-centered support. Peripheral nutrients add some complexity without strong sleep relevance; the product is priced competitively within basic sleep supplements.

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Report analysis

Goals

Sleep Support
Sleep Support
Impact
High effect
A Goal FitB Strength of SupportC+ CoverageD+ Formula Quality
Melatonin · 3 mg

Melatonin gives direct sleep signaling, while valerian adds a modest calming component. The 3 mg melatonin amount is useful, but the 100 mg valerian extract lacks potency details and appears underpowered.

Glutamine, vitamin E, calcium, and grape seed extract add little direct sleep value. Melatonin and valerian may increase drowsiness with alcohol or sedative medicines and can impair alertness after use.

Study evidence
Melatonin Supportive 181 studies
Valerian Supportive 31 studies
Stress Relief
Stress Relief
Impact
Moderate effect
C- Goal FitD Strength of SupportD+ CoverageD+ Formula Quality

Melatonin and valerian make the formula relevant when stress disrupts sleep. The 3 mg melatonin amount is useful, but the 100 mg valerian amount is modest and lacks standardization.

Glutamine, vitamin E, calcium, and grape seed extract add little direct support for the selected goal. Nighttime drowsiness is expected, and the blend should not be used when alertness is required.

Study evidence
Melatonin Supportive 21 studies
Valerian Supportive 18 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopheryl Succinate)
 25 mg
Calcium (Calcium Carbonate)
 70 mg
L-Glutamine
800 mg
Valerian extract
100 mg
Grape Seed Extract (Polyphenols)
 25 mg
Melatonin
3 mg
Adults 18–50 Dairy Free Vegetarian
Report overview
Valerian · 100 mg OverallScore62
D Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyA+ Value

The valerian extract amount is modest, and no concentration ratio or active-marker level is given. Tablet delivery manages odor less effectively than a capsule and may dissolve more slowly. Low cost per serving and clear standalone dosing are the main strengths.

View ingredientView products
Melatonin · 3 mg OverallScore60
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

The standard format may start more slowly and offers no stated overnight-release support. The dose aligns well with physiological sleep signaling. The serving cost is above the median but remains moderate.

View ingredientView products
Glutamine · 800 mg OverallScore58
B- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyD- Value

The clearly disclosed L-glutamine amount is low for gut-focused therapeutic use, and the tablet carries no premium grade claim. Several tablets would be needed to reach a practical glutamine amount, while the formula is designed mainly for sleep support. Melatonin and valerian may cause drowsiness, so taking it before driving or combining it with alcohol or sedative medicines could impair alertness. The cost per gram of glutamine is relatively high.

View ingredientView products
Loading alternative details
79 Performance

Sleep Optimizer

Jarrow Formulas
<p>Stronger formulation focus comes from 400 mg valerian complex, 300 mg tryptophan, GABA, hops, lemon balm, and low-dose melatonin. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the coherent blend offers more sleep-specific depth while keeping melatonin modest.</p>
76 Performance

Best-Rest Formula

Pure Encapsulations
<p>Stronger formulation focus comes from 300 mg GABA, 400 mg valerian extract, 1 mg melatonin, branded L-theanine, and standardized calming herbs. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the conservative melatonin dose and lack of 5-HTP avoid part of the original serotonin-related trade-off.</p>
75 Performance

Ortho Sleep

AOR Advanced Orthomolecular Research Advanced
<p>Stronger formulation focus comes from 300 mg lemon balm, 200 mg L-theanine, 150 mg valerian, 100 mg GABA, and 3 mg melatonin. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the disclosed multi-pathway blend is well aligned with sleep, but 5-HTP still requires care with serotonin-raising medicines.</p>
71 Budget

Sleep Essentials

Swanson
<p>Lower recurring cost is paired with 3 mg melatonin with valerian, chamomile, hops, skullcap, and passionflower. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, it adds several calming herbs at a much lower recurring cost, although their doses and standardization are modest.</p>
68 Budget

Super Snooze Melatonin with Herbal Blend

Sundown Naturals
<p>Lower recurring cost is paired with 5 mg melatonin with valerian, hops, chamomile, passionflower, and taurine. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, full amount disclosure and a long supply improve practicality, though the melatonin amount is less conservative.</p>
79 Budget

Sleep Optimizer

Jarrow Formulas
<p>Lower recurring cost is paired with 400 mg valerian complex, 300 mg tryptophan, GABA, hops, lemon balm, and low-dose melatonin. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the coherent blend offers more sleep-specific depth while keeping melatonin modest.</p>
77 Value

Lights Out Sleep

ALLMAX
<p>A better quality-to-cost balance comes from 250 mg valerian extract, 150 mg GABA, 3 mg melatonin, active vitamin B6, and several calming herbs. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, it keeps broad sleep coverage while using a more moderate 5-HTP amount.</p>
72 Value

Power to Sleep PM

Irwin Naturals
<p>A better quality-to-cost balance comes from valerian, ashwagandha, hops, lemon balm, passionflower, GABA, L-theanine, and 2 mg melatonin. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the larger supply pairs broad sleep coverage with better value, although GABA and L-theanine are modest.</p>
73 Value

Driftoff

ZHOU
<p>A better quality-to-cost balance comes from 2 mg melatonin with valerian, GABA, tryptophan, chamomile, passionflower, lemon balm, and hops. Compared with the original’s melatonin-led formula with modest valerian and limited-purpose glutamine, the formula is more completely centered on sleep, but most botanical potency details are missing.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  2. Assessment of Valeriana officinalis l. (Valerian) for Conscious Sedation of Patients During the Extraction of Impacted Mandibular Third Molars: A Randomized, Split-Mouth, Double-Blind, Crossover Study.
    Farah GJ; Ferreira GZ; Danieletto-Zanna CF; Luppi CR; Jacomacci WP · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2020
    Randomized trial20 participantsStress Relief forValerian
  3. Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials.
    Fernández-San-Martín MI; Masa-Font R; Palacios-Soler L; Sancho-Gómez P; Calbó-Caldentey C; Flores-Mateo G · Sleep medicine · 2010
    Meta-analysis18 studies pooledSleep Support forValerian
  4. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  5. Complementary and alternative treatments for insomnia disorder: a systematic umbrella review.
    Ell J; Schmid SR; Benz F; Spille L · Journal of sleep research · 2024
    Systematic review15 studies pooledSleep Support forValerian
  6. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledStress Relief forValerian
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial.
    Velasquez ACA; Tsuji M; Dos Santos Cordeiro L; Petinati MFP; Rebellato NLB; Sebastiani AM; da Costa DJ; Scariot R · Oral and maxillofacial surgery · 2024
    Randomized trial54 participantsStress Relief forValerian
  9. Comparison the effect of valerian and gabapentin on RLS and sleep quality in hemodialysis patients: A randomized clinical trial.
    Hajizadeh I; Jamshidi M; Kazemi M; Kargar H; Sadeghi T · Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023
    Randomized trial40 participantsSleep Support forValerian
  10. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  11. Valerian for sleep: a systematic review and meta-analysis.
    Bent S; Padula A; Moore D; Patterson M; Mehling W · The American journal of medicine · 2006
    Meta-analysis1,093 participants16 studies pooledSleep Support forValerian
  12. Effect of kava and valerian on human physiological and psychological responses to mental stress assessed under laboratory conditions.
    Cropley M; Cave Z; Ellis J; Middleton RW · Phytotherapy research : PTR · 2002
    Non-randomized trial54 participantsStress Relief forValerian
  13. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  14. Does valerian work for insomnia? An umbrella review of the evidence.
    Valente V; Machado D; Jorge S; Drake CL; Marques DR · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2024
    Systematic review8 studies pooledSleep Support forValerian
  15. Valerian for anxiety disorders.
    Miyasaka LS; Atallah AN; Soares BG · The Cochrane database of systematic reviews · 2007
    Systematic review36 participants1 studies pooledStress Relief forValerian
  16. Melatonin Treatment for Sleep Disorders in Parkinson's Disease: A Meta-Analysis and Systematic Review.
    Ma H; Yan J; Sun W; Jiang M; Zhang Y · Frontiers in aging neuroscience · 2022
    Meta-analysis7 studies pooledSleep Support forMelatonin
  17. Clinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
    Sateia MJ; Buysse DJ; Krystal AD; Neubauer DN; Heald JL · Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2017
    Guideline / consensusSleep Support forValerian
  18. Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review.
    Araújo JO; Bergamaschi CC; Lopes LC; Guimarães CC; de Andrade NK; Ramacciato JC; Motta RHL · BMJ open · 2021
    Systematic review327 participants12 studies pooledStress Relief forValerian
  19. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  20. Efficacy and tolerability of valerian extract LI 156 compared with oxazepam in the treatment of non-organic insomnia--a randomized, double-blind, comparative clinical study.
    Ziegler G; Ploch M; Miettinen-Baumann A; Collet W · European journal of medical research · 2003
    Randomized trial202 participantsSleep Support forValerian
  21. Stress-induced insomnia treated with kava and valerian: singly and in combination.
    Wheatley D · Human psychopharmacology · 2019
    Single-arm trial24 participantsStress Relief forValerian
  22. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  23. Herbal medicine for insomnia: A systematic review and meta-analysis.
    Leach MJ; Page AT · Sleep medicine reviews · 2016
    Meta-analysis1,602 participants14 studies pooledSleep Support forValerian
  24. [Use of valerian in anxiety and sleep disorders: what is the best evidence?].
    Nunes A; Sousa M · Acta medica portuguesa · 2012
    Systematic review4 studies pooledStress Relief forValerian
  25. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  26. Valerian for insomnia: a systematic review of randomized clinical trials.
    Stevinson C; Ernst E · Sleep medicine · 2019
    Systematic review9 studies pooledSleep Support forValerian
  27. GABA-modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence.
    Savage K; Firth J; Stough C; Sarris J · Phytotherapy research : PTR · 2018
    Systematic review10 studies pooledStress Relief forValerian
  28. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  29. A systematic review of insomnia and complementary medicine.
    Sarris J; Byrne GJ · Sleep medicine reviews · 2011
    Systematic review20 studies pooledSleep Support forValerian
  30. Medicinal Plants for Insomnia Related to Anxiety: An Updated Review.
    Borrás S; Martínez-Solís I; Ríos JL · Planta medica · 2021
    Systematic reviewStress Relief forValerian
  31. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  32. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  33. Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study.
    Chandra Shekhar H; Joshua L; Thomas JV · Advances in therapy · 2024
    Randomized trial80 participantsSleep Support Stress Relief forValerian
  34. Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial.
    Schicktanz N; Gerhards C; Schlitt T; Aerni A; Müggler E; de Quervain D; Papassotiropoulos A; Boonen G; Drewe J; Butterweck V · Brain and behavior · 2025
    Randomized trial40 participantsSleep Support forValerian
  35. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  36. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  37. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  38. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  39. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin