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Pure Heart

Swanson
4.7
★ ★ ★ ★ ★
(181 ratings)
Policosanol 20 mg
Resveratrol 150 mg
Product Image
Score79
Clear, useful amounts of grape seed, trans-resveratrol, and sugar-cane policosanol create a strong once-daily formula. Missing purity and standardization details are the main limitations.
How scoring works
Quantity:60 Veggie Cap(s) • (60 servings)
Goals:
Cardiovascular Support
Anti-Aging
Anti-Inflammatory Support
Metabolism Boost

Score 79

Clear, useful amounts of grape seed, trans-resveratrol, and sugar-cane policosanol create a strong once-daily formula. Missing purity and standardization details are the main limitations.
How scoring works
$22.89($0.38 per serving)
Amazon
$ 22.89
iHerb
$ 0.00
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Analysis

The capsule combines 300 mg of MegaNatural-BP grape-seed extract with 150 mg of trans-resveratrol and 20 mg of sugar-cane policosanol. Those amounts provide meaningful antioxidant and vascular coverage in a simple once-daily format.

The trans isomer and botanical sources are named, which improves label clarity. Resveratrol purity and enhanced delivery are not specified, while the policosanol entry does not state octacosanol content.

One vegetable capsule and favorable cost make the formula practical. Its best fit is broad cardiovascular antioxidant support rather than a high-potency resveratrol or fully standardized policosanol program.

Who is it for
  • Adults seeking combined antioxidant and vascular support
  • Users who want trans-resveratrol with grape seed
  • People who prefer a one-capsule formula
Best for
  • Broad cardiovascular antioxidant support
  • Combining resveratrol with grape-seed extract
  • Once-daily botanical use

Pros

  • Uses branded grape-seed extract
  • Identifies trans-resveratrol
  • Provides target-range sugar-cane policosanol
  • Clearly states all active amounts
  • Offers favorable serving value

Cons

  • Resveratrol purity percentage is absent
  • No enhanced resveratrol delivery is provided
  • Knotweed emodin removal is not verified
  • Policosanol octacosanol content is not stated

Warnings

  • Resveratrol and grape-seed extract may increase bleeding risk with anticoagulant or antiplatelet medicines.
  • Residual emodin from Japanese knotweed may cause loose stools or cramping in sensitive users.
  • Policosanol may add cholesterol- or blood-pressure-lowering effects to related medicines.

Nutrient quality

84 Highest impact

Branded grape-seed extract and identified trans-resveratrol support solid ingredient quality. Grape-seed extract, trans-resveratrol, and sugar-cane policosanol are supplied in useful amounts.

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Ingredient transparency

81 Highest impact

Every supplied active ingredient has a specific amount. No proprietary blend hides a meaningful active dose.

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Customer satisfaction

60 Moderate impact

The supplied aggregate rating is strong, although no specific comments are included. The moderate rating count provides a useful aggregate signal.

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Value for money

86 Highest impact

Formula quality provides reasonable support for the product positioning. Serving utility appears reasonable, while the formula avoids obvious low-value padding.

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Goals

Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
B+ Goal FitB+ Strength of SupportB+ CoverageA Formula Quality

Grape seed extract and trans-resveratrol provide antioxidant and endothelial support, while policosanol adds a lipid-focused route. The combination addresses several cardiovascular pathways without becoming overly crowded.

Branded grape seed material and clearly identified trans-resveratrol support confidence, although resveratrol purity and emodin removal are not stated. Grape seed and resveratrol may add to bleeding risk when combined with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 73 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B- Goal FitA Strength of SupportB- CoverageB+ Formula Quality

Grape seed extract and trans-resveratrol address vascular function, oxidative stress, and cellular signaling relevant to healthy aging. Policosanol fits the cardiovascular theme but has weak and poorly replicated human evidence.

The grape seed and resveratrol amounts are substantial and individually disclosed. The formula is coherent, though its longevity case relies more on vascular markers than demonstrated healthspan outcomes.

Study evidence
Resveratrol No effect 7 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C Goal FitB- Strength of SupportB CoverageA- Formula Quality

Grape-seed extract and trans-resveratrol provide complementary antioxidant and vascular signaling support. Policosanol adds a separate lipid-related component, though it is less central to inflammatory balance.

The main botanical amounts are meaningful and the trans isomer of resveratrol is identified. Resveratrol may add to bleeding tendency when used with anticoagulant or antiplatelet medicines.

Study evidence
Resveratrol Supportive 34 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
C Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Resveratrol · 150 mg

Trans-resveratrol may support insulin signaling and mitochondrial regulation, giving the formula a plausible metabolic role. Human results are less consistent than for direct thermogenic agents or foundational cofactors.

The 150 mg trans-resveratrol amount is supportive, but no purity percentage or enhanced delivery system is disclosed. Grape seed extract and policosanol create a coherent cardiovascular blend, though their overlap adds limited metabolic breadth.

Study evidence
Resveratrol Supportive 21 studies
Skin Health
Skin Health
Impact
Moderate effect
D Goal FitC- Strength of SupportD CoverageC+ Formula Quality
Resveratrol · 150 mg

Grape-seed polyphenols and trans-resveratrol offer indirect antioxidant support relevant to skin aging. The formula is primarily cardiovascular and does not supply collagen, ceramides, or established skin nutrients.

Trans-resveratrol is named clearly, but purity and enhanced delivery are not disclosed. Knotweed-derived resveratrol may retain emodin and cause laxative effects when removal is not verified.

Study evidence
Resveratrol Supportive 7 studies

Ingredients

IngredientAmount per serving
MegaNatural-BP Grape seed extract
300 mg
Policosanol (Saccharum officinarum)
 20 mg
Trans-Resveratrol (Polygonum cuspidatum root extract)
 150 mg
Adults 18–50
Report overview
Policosanol (Saccharum officinarum) · 20 mg OverallScore78
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

Sugar-cane policosanol is provided at the collection target amount with clear label disclosure. Missing octacosanol standardization leaves the active fatty-alcohol profile uncertain. Grape seed extract and resveratrol broaden the formula, though the serving cost remains above the collection midpoint.

View ingredientView products
Resveratrol (Polygonum cuspidatum root extract) · 150 mg OverallScore59
C Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyB Value

The label specifies the active trans isomer, but it does not state a purity percentage or use enhanced delivery technology. The amount is supportive rather than therapeutic, and the knotweed source lacks emodin-removal verification, which may raise the chance of mild laxative effects. Cost efficiency is favorable for the disclosed active amount.

View ingredientView products
Loading alternative details
80 Performance

TransMax TR

Biotivia
<p>MicroActive delivery and a substantial trans-resveratrol amount address absorption and provide deeper resveratrol coverage than the original. It omits policosanol and grape-seed extract, while knotweed purity and emodin-removal details remain unavailable.</p>
81 Performance

Resveratrol 250 mg with Red Wine Extract

Solgar
<p>A higher trans-resveratrol amount in a fat-containing softgel offers stronger resveratrol depth and more delivery support than the original capsule. Red-wine extract adds a small complementary component, though policosanol and grape-seed extract are absent.</p>
83 Performance

High Potency Trans-Resveratrol 600 mg

Doctor's Best
<p>A clearly identified, high trans-resveratrol amount provides much greater single-ingredient depth than the original. The plain capsule lacks a delivery aid, and purity and emodin-removal details are not supplied.</p>
82 Budget

Policosanol 10 mg

NOW
<p>Sugar-cane policosanol provides a focused version of one original active at a much lower recurring cost. It omits grape-seed extract and trans-resveratrol, so antioxidant and multi-pathway coverage are narrower.</p>
80 Budget

Resveratrol Plus

Country Life
<p>Trans-resveratrol with grape-seed, grape-skin, and pine-bark extracts preserves broad polyphenol coverage at a lower recurring cost. It omits policosanol, and incomplete standardization and emodin-removal details leave some uncertainty.</p>
80 Budget

Resveratrol 100 mg

Life Extension
<p>Trans-resveratrol from grape and knotweed plus quercetin offers focused antioxidant coverage at a lower recurring cost. Duplicate source entries make the total resveratrol amount unclear, and policosanol is absent.</p>
84 Value

Policosanol 20 mg

Source Naturals
<p>Meaningfully dosed sugar-cane policosanol matches the original policosanol amount in a simpler, highly cost-effective formula. It does not replace the original's trans-resveratrol or grape-seed extract coverage.</p>
79 Value

Double Strength Policosanol 20 mg

NOW
<p>Sugar-cane policosanol anchors an economical blend with artichoke, milk thistle, alpha-lipoic acid, and grape-seed extract. It preserves some cardiovascular and antioxidant breadth but omits trans-resveratrol, and supporting botanical standardization is incomplete.</p>
78 Value

Trans-Resveratrol 200 With ResVinol

Doctor's Best
<p>A stronger trans-resveratrol amount plus added polyphenols offers useful antioxidant depth with competitive value. Generic polyphenol naming and missing source and purity details reduce transparency, and policosanol is absent.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsAnti-Aging forResveratrol
  2. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Aging forResveratrol
  3. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsAnti-Aging forResveratrol
  4. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledAnti-Aging forResveratrol
  5. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsAnti-Aging Skin Health forResveratrol
  6. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  7. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  8. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  9. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsAnti-Inflammatory Support forResveratrol
  10. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  11. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  12. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  13. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  14. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support forResveratrol
  15. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  16. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Boost forResveratrol
  17. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Boost forResveratrol
  18. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Boost forResveratrol
  19. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Boost forResveratrol
  20. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Boost forResveratrol
  21. Efficacy and safety of Resveratrol combined with Ablative Fractional CO2 laser system in the treatment of skin photoaging.
    Du YM; Zeng J; Li M; Wang YB; Wu Y; Qi RQ; Gao XH; Chen HD · Journal of cosmetic dermatology · 2021
    Non-randomized trial32 participantsSkin Health forResveratrol
  22. Exploring resveratrol-enriched collagen dressings for diabetic foot ulcers: A retrospective study of wound healing outcomes.
    Sezikli İ; Kendirci M · Journal of tissue viability · 2025
    Cohort study41 participantsSkin Health forResveratrol
  23. Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
    Moyano-Mendez JR; Fabbrocini G; De Stefano D; Mazzella C; Mayol L; Scognamiglio I; Carnuccio R; Ayala F; La Rotonda MI; De Rosa G · Drug development and industrial pharmacy · 2016
    Clinical trialSkin Health forResveratrol
  24. Resveratrol-Loaded Lipid Nanocarriers: Correlation between In Vitro Occlusion Factor and In Vivo Skin Hydrating Effect.
    Montenegro L; Parenti C; Turnaturi R; Pasquinucci L · Pharmaceutics · 2020
    Clinical trial12 participantsSkin Health forResveratrol