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Serenelle

Quality Of Life
4.5
★ ★ ★ ★ ★
(316 ratings)
Theanine 200 mg
Ashwagandha 250 mg
GABA 125 mg
Product Image
Score78
A focused, well-dosed calming formula with strong ingredient choices and only modest label-detail gaps.
How scoring works
Quantity:60 Vegicap(s) • (30 servings)
Goals:
Stress Relief
Mood Support
Brain Health
Sleep Support
Cognitive Support
Productivity Boost
Mental Focus

Score 78

A focused, well-dosed calming formula with strong ingredient choices and only modest label-detail gaps.
How scoring works
$23.49($0.78 per serving)
Pure Formulas
$ 23.49
iHerb
$ 24.96
Report prices

Analysis

Sensoril ashwagandha and 200 mg of theanine provide a strong base for stress and relaxation support. Lemon balm adds a complementary calming botanical rather than an unrelated filler.

PharmaGABA is clearly named and supplies a modest additional pathway. The combination is more directly aligned with relaxation, mood, and sleep preparation than with daytime productivity.

The formula is compact and avoids a crowded blend. Complete inactive ingredients and timing directions should be checked before use, especially if daytime alertness is important.

Who is it for
  • Adults seeking daytime or evening calm
  • People who want an ashwagandha-theanine combination
  • Users avoiding melatonin
Best for
  • Stress support
  • Evening relaxation
  • Sleep preparation

Pros

  • Uses branded Sensoril ashwagandha
  • Purposeful theanine amount
  • Focused four-ingredient design

Cons

  • Intake timing is not supplied
  • Full inactive ingredients are unclear
  • May be too calming for productivity use

Warnings

  • The combined calming ingredients may cause drowsiness
  • Ashwagandha may affect thyroid function and warrants caution with thyroid disorders or medication
  • Avoid combining with alcohol or other sedatives until individual response is known

Nutrient quality

93 Highest impact

Branded forms, meaningful doses, and tight ingredient selection create a strong calming formula. No major dosing or formula-coherence weakness is evident from the supplied facts.

.

Ingredient transparency

74 High impact

Most active names and total amounts are visible. Repeated source entries and missing non-active ingredients reduce clarity.

.

Customer satisfaction

60 Moderate impact

The supplied average rating is mixed. No specific review comments were supplied, so repeated negative experiences cannot be assessed.

.

Value for money

82 Highest impact

Branded, meaningfully dosed actives provide solid value. The relatively costly serving limits category leadership.

.
Report analysis

Goals

Stress Relief
Impact
Highest effect
A+ Goal FitA+ Strength of SupportA+ CoverageA+ Formula Quality
Ashwagandha · 250 mgGABA · 125 mgTheanine · 200 mg

Sensoril ashwagandha, L-theanine, PharmaGABA, and lemon balm provide a well-targeted mix for acute calm and stress resilience. The main actives use recognized forms and sit at meaningful disclosed amounts.

The formula covers both inhibitory signaling and stress-response regulation without unnecessary extras. Additive calming effects may cause drowsiness in sensitive users or when combined with sedatives.

Study evidence
Ashwagandha Supportive 47 studies
GABA Supportive 6 studies
Theanine Supportive 16 studies
Mood Support
Impact
Highest effect
A- Goal FitA Strength of SupportA CoverageA+ Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha supports stress resilience, while L-theanine, lemon balm, and PharmaGABA support calm and relaxed attention. The labeled amounts are well aligned and cover complementary mood-related pathways.

Branded extracts and complete quantity disclosure make the formula easy to assess. The combined calming ingredients may cause drowsiness in sensitive users, so caution is appropriate before driving.

Study evidence
Ashwagandha Supportive 29 studies
GABA Supportive 12 studies
Theanine Supportive 12 studies
Brain Health
Impact
Highest effect
A- Goal FitA Strength of SupportA- CoverageA Formula Quality
Ashwagandha · 250 mg

Sensoril ashwagandha, theanine, lemon balm, and PharmaGABA create a strong mental-resilience and calming formula. The branded ashwagandha and GABA forms, plus a well-sized theanine amount, strengthen dose and quality confidence.

The formula focuses on calm and stress adaptation rather than memory, neuronal energy, or structural support. The combined calming ingredients may cause drowsiness in sensitive users.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 17 studies
Sleep Support
Impact
Highest effect
B Goal FitA Strength of SupportB+ CoverageA+ Formula Quality
Theanine · 200 mg

The focused blend combines well-dosed L-theanine, branded Sensoril ashwagandha, lemon balm, and PharmaGABA to support relaxation and stress-related sleep difficulty. The main limitation is that it does not directly address circadian timing.

Every active amount is disclosed, and the branded ashwagandha and GABA sources improve formulation confidence. Its few ingredients are supplied at purposeful amounts, giving the formula more depth than many broad herbal blends.

Study evidence
Ashwagandha Supportive 18 studies
GABA Supportive 4 studies
Theanine Supportive 8 studies
Cognitive Support
Impact
Highest effect
B Goal FitA- Strength of SupportB CoverageA- Formula Quality
Ashwagandha · 250 mgTheanine · 200 mg

Suntheanine-like calm-focus support from L-theanine combines with Sensoril ashwagandha and lemon balm for stress-related cognitive strain. The stack is better suited to calmness and resilience than acute alertness or memory recall.

Branded Sensoril and meaningful theanine amounts strengthen quality. GABA, lemon balm, theanine, and ashwagandha may have additive calming effects and can cause drowsiness in sensitive users.

Study evidence
Ashwagandha Supportive 17 studies
Theanine Supportive 25 studies
Productivity Boost
Impact
High effect
B Goal FitA- Strength of SupportB- CoverageB- Formula Quality
Theanine · 200 mg

The formula may improve productivity when stress or anxious tension is consuming attention. Branded ashwagandha, L-theanine, lemon balm, and PharmaGABA provide substantial calming support rather than direct stimulation.

The amounts and branded extracts are well disclosed, giving the formula good dosing confidence. Additive calming effects may cause drowsiness in sensitive users and could reduce output when baseline alertness is already low.

Study evidence
Ashwagandha Supportive 6 studies
Theanine Supportive 5 studies
Mental Focus
Impact
High effect
B- Goal FitB+ Strength of SupportB- CoverageB+ Formula Quality
Theanine · 200 mg

L-theanine, Sensoril ashwagandha, lemon balm, and PharmaGABA create a credible formula for concentration disrupted by stress. Theanine and branded ashwagandha are both supplied at useful amounts with supportive human evidence.

The profile favors relaxed clarity rather than alertness, rapid processing, or broad neurotransmitter support. Exact amounts and named branded extracts make the main contributions easy to judge, though GABA and lemon balm add more calming than direct focus depth.

Study evidence
Ashwagandha Supportive 12 studies
Theanine Supportive 19 studies

Ingredients

IngredientAmount per serving
Lemon Balm leaf extract (Relesse)
300 mg
Sensoril Ashwagandha extract (Oligosaccharides, Withanolide Glycoside Conjugates)
250 mg
L-Theanine
200 mg
PharmaGABA
125 mg
Gluten Free Adults 18–50 Vegetarian
Report overview
Theanine · 200 mg OverallScore88
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The clearly identified L-theanine is provided at a well-aligned amount and is fully disclosed. No branded theanine source or specific purity verification is shown. A meaningful dose of branded Sensoril ashwagandha improves the value of this multi-ingredient formula despite premium theanine pricing.

A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC- Value

A clinically studied Sensoril extract provides strong form quality at a well-aligned dose. The exact amount is clear, though the formula has no dedicated absorption enhancer. The moderate price premium reduces value but is partly supported by the branded extract.

GABA · 125 mg OverallScore81
A Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value
PharmaGABA provides a clearly disclosed premium form at a dose suited to a multi-ingredient stress formula. The vegetable capsule offers a practical delivery format, while the supporting lemon balm, ashwagandha, and L-theanine make the formula broader than a standalone GABA supplement. Its relatively high cost per serving weakens value despite the higher-quality GABA source.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.
    Fatima K; Malik J; Muskan F; Raza G; Waseem A; Shahid H; Jaffery SF; Khan U; Zaheer MK; Shaikh Y; Rashid AM · Human psychopharmacology · 2024
    Meta-analysis254 participants5 studies pooledStress Relief Mood Support forAshwagandha
  2. The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial.
    O'Connor J; Lindsay K; Baker C; Kirby J; Hutchins A; Harris M · Journal of medicinal food · 2022
    Randomized trial60 participantsStress Relief forAshwagandha
  3. Dual impact of Ashwagandha: Significant cortisol reduction but no effects on perceived stress - A systematic review and meta-analysis.
    Albalawi AA · Nutrition and health · 2025
    Meta-analysis488 participants13 studies pooledStress Relief forAshwagandha
  4. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsStress Relief Mood Support forTheanine
  5. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsStress Relief Sleep Support forTheanine
  6. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  7. Acute and Repeated Ashwagandha Supplementation Improves Markers of Cognitive Function and Mood.
    Leonard M; Dickerson B; Estes L; Gonzalez DE; Jenkins V; Johnson S; Xing D; Yoo C; Ko J; Purpura M; Jäger R; Faries M; Kephart W; Sowinski R; Rasmussen CJ; Kreider RB · Nutrients · 2024
    Randomized trial59 participantsBrain Health Cognitive Support forAshwagandha
  8. Effect of ashwagandha (Withania somnifera) extract with Sominone (Somin-On™) to improve memory in adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study.
    Rai HP; Mishra DN · Journal of psychopharmacology (Oxford, England) · 2025
    Randomized trial40 participantsBrain Health Cognitive Support Mental Focus forAshwagandha
  9. Efficacy of Withania somnifera supplementation on adult's cognition and mood.
    Remenapp A; Coyle K; Orange T; Lynch T; Hooper D; Hooper S; Conway K; Hausenblas HA · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial60 participantsBrain Health Cognitive Support Productivity Boost forAshwagandha
  10. A clinical assessment of the therapeutic effects of Ashwagandha root extract on cognitive performance, sleep, and fatigue in children aged 6-12 years.
    Saxena A; Lopresti A; Sharif M; Elon N; Suri R; Langade DK · Frontiers in nutrition · 2026
    Randomized trial85 participantsBrain Health Mental Focus forAshwagandha
  11. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study.
    Gopukumar K; Thanawala S; Somepalli V; Rao TSS; Thamatam VB; Chauhan S · Evidence-based complementary and alternative medicine : eCAM · 2022
    Randomized trial130 participantsBrain Health Sleep Support Stress Relief forAshwagandha
  12. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  13. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  14. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  15. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  16. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  17. A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.
    Majeed M; Nagabhushanam K; Mundkur L · Medicine · 2023
    Randomized trial54 participantsCognitive Support Mental Focus forAshwagandha
  18. Efficacy and safety of ashwagandha root extract in children and adolescents with mild attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled trial.
    Naik S; Muralidhar G; Rao BS; Agarwal S; Jain M · Journal of medicine and life · 2026
    Randomized trial58 participantsCognitive Support Mental Focus forAshwagandha
  19. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  20. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  21. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions.
    Choudhary D; Bhattacharyya S; Bose S · Journal of dietary supplements · 2018
    Randomized trial50 participantsMental Focus forAshwagandha
  22. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  23. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  24. A proprietary herbal extract of ashwagandha root for stress and anxiety in healthy adults: a randomized, double-blind, three-arm, placebo-controlled efficacy and safety study.
    West RE; Biswas A; Rao R; Tayade H; Ademola J · Journal of medicine and life · 2026
    Randomized trial141 participantsMood Support forAshwagandha
  25. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults.
    Chandrasekhar K; Kapoor J; Anishetty S · Indian journal of psychological medicine · 2013
    Randomized trial64 participantsMood Support Stress Relief forAshwagandha
  26. Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study.
    McKinney E; Stewart J; Kewalramani R; Singh S · Trials · 2026
    Randomized trial186 participantsMood Support forAshwagandha
  27. Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
    Zhang W; Yan Y; Wu Y; Yang H; Zhu P; Yan F; Zhao R; Tian P; Wang T; Fan Q; Su Z · Pharmacological research · 2022
    Meta-analysis29 participants29 studies pooledMood Support forAshwagandha
  28. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  29. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  30. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  31. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  32. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  33. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  34. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  35. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine Stress Relief forGABA
  36. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  37. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis.
    Cheah KL; Norhayati MN; Husniati Yaacob L; Abdul Rahman R · PloS one · 2021
    Meta-analysis400 participants5 studies pooledProductivity Boost forAshwagandha
  38. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study.
    Langade D; Thakare V; Kanchi S; Kelgane S · Journal of ethnopharmacology · 2021
    Randomized trial80 participantsProductivity Boost Sleep Support forAshwagandha
  39. Effect of standardized aqueous extract of Withania somnifera on tests of cognitive and psychomotor performance in healthy human participants.
    Pingali U; Pilli R; Fatima N · Pharmacognosy research · 2014
    Randomized trial20 participantsProductivity Boost forAshwagandha
  40. Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study.
    Kale S; Lopresti A; Suri R; Garg N; Langade D · Journal of psychoactive drugs · 2026
    Randomized trial120 participantsProductivity Boost forAshwagandha
  41. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledProductivity Boost forTheanine
  42. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  43. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  44. A randomized, double blind, placebo controlled study to evaluate the effects of ashwagandha (Withania somnifera) extract on sleep quality in healthy adults.
    Deshpande A; Irani N; Balkrishnan R; Benny IR · Sleep medicine · 2021
    Randomized trial150 participantsSleep Support forAshwagandha
  45. Efficacy and safety of Ashwagandha root extract sustained-release (AshwaSR) capsules in healthy adult, stressed subjects: A randomized, double-blind, placebo-controlled, parallel-group, 3-arm clinical trial.
    Thanawala S; Shah R; Alluri KV; Bhupathiraju K; Desomayanandanam P; Bhuvenendran A · Medicine · 2026
    Randomized trial135 participantsSleep Support forAshwagandha
  46. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study.
    Langade D; Kanchi S; Salve J; Debnath K; Ambegaokar D · Cureus · 2020
    Randomized trial60 participantsSleep Support forAshwagandha
  47. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  48. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  49. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  50. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  51. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  52. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  53. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  54. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
    Lopresti AL; Smith SJ; Malvi H; Kodgule R · Medicine · 2019
    Randomized trial60 participantsStress Relief forAshwagandha
  55. Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels.
    Mishra DN; Kumar M · Heliyon · 2024
    Randomized trial60 participantsStress Relief forAshwagandha
  56. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
    Salve J; Pate S; Debnath K; Langade D · Cureus · 2020
    Randomized trial60 participantsStress Relief forAshwagandha
  57. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  58. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  59. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine