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Gentle Iron 25 mg

4.8
★ ★ ★ ★ ★
(55761 ratings)
Iron 25 mg
Product Image
Score86
The chelated form offers good absorption and digestive tolerance in a focused formula. The formula does not add vitamin C, folate, or vitamin B12.
How scoring works
Capsule
Quantity:180 Capsule(s) • (180 servings)
Goals:
Hair Health
Energy
Productivity Boost
Mental Focus

Score 86

The chelated form offers good absorption and digestive tolerance in a focused formula. The formula does not add vitamin C, folate, or vitamin B12.
How scoring works
$16.60($0.09 per serving)
iHerb
$ 16.60
Vitacost
$ 17.63
Pure Formulas
$ 17.62
Daily Vita
$ 19.40
Amazon
$ 16.60
Vitacost
$ 17.63
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Analysis

iron bisglycinate chelate supplies 25 mg of iron in one capsule. The chelated form offers good absorption and digestive tolerance in a focused formula.

The amount may help energy, hair, and mental focus when iron status is low. A large bottle and very low serving cost make it efficient for longer clinician-guided use.

The formula does not add vitamin C, folate, or vitamin B12. Iron status and the reason for supplementation should guide duration and dose.

Who is it for
  • Adults with verified low iron
  • People needing a longer bottle supply
  • Users who favor chelated iron
Best for
  • Long-term monitored supplementation
  • Low-cost bisglycinate
  • Single-capsule use

Pros

  • Well-absorbed bisglycinate form
  • Effective 25 mg amount
  • Large bottle with 180 servings
  • Very low serving cost

Cons

  • No vitamin C
  • No folate or vitamin B12
  • Requires a confirmed reason for ongoing iron use

Warnings

  • The 25 mg amount can cause constipation, nausea, or dark stools.
  • Use iron for a confirmed need; unnecessary intake can accumulate, particularly in people with hemochromatosis or other iron-overload conditions.
  • Iron can reduce absorption of levothyroxine and some tetracycline or quinolone antibiotics, so separate doses as directed by a pharmacist.
  • Keep iron supplements away from children because accidental ingestion can cause serious iron poisoning.

Nutrient quality

89 Highest impact

A useful bisglycinate amount provides strong targeted iron quality. The substantial dose remains appropriate only when an iron need has been identified.

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Ingredient transparency

84 Highest impact

The iron form and amount are specific, with no hidden blend. Intake directions and non-active ingredients were not included in the supplied details.

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Customer satisfaction

73 High impact

The available satisfaction metric is favorable and the sample provides useful confidence. Specific experience details are absent, so repeated complaints and purpose fit remain uncertain.

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Value for money

96 Highest impact

Strong active quality and a very low serving cost provide excellent value. The focused formula is competitive without relying on weak extras.

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Report analysis

Goals

Hair Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Iron · 25 mg

Chelated iron can help reduce shedding when iron deficiency or low iron stores are the cause. It should not be used as a general hair-growth supplement without confirming need, because excess iron offers no follicle benefit and can be harmful.

Iron bisglycinate is a well-absorbed and often gentler form at a clearly disclosed 25 mg amount. Iron can still cause constipation or nausea, is unsafe with iron-overload disorders, and must be kept away from children because overdose can be fatal.

Study evidence
Iron Disputed 25 studies
Energy
Impact
Highest effect
B+ Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Iron · 25 mg

Iron bisglycinate provides a well-absorbed amount that can improve oxygen transport when iron deficiency contributes to fatigue. The chelated form is generally gentler and more useful than basic iron salts.

Iron is not a general energy booster and should not be used routinely without a demonstrated need. Unnecessary supplementation can cause constipation or nausea and may build harmful iron stores in people prone to iron overload.

Study evidence
Iron Supportive 74 studies
Productivity Boost
Impact
High effect
B- Goal FitA Strength of SupportD CoverageA- Formula Quality
Iron · 25 mg

Iron bisglycinate can improve energy and concentration when iron deficiency is the cause of fatigue. People with adequate iron stores should not expect a direct focus boost.

The chelated form is well absorbed and generally gentler than common iron salts. Iron should be used for a demonstrated need because unnecessary intake can cause harm or iron overload.

Study evidence
Iron Supportive 69 studies
Mental Focus
Impact
High effect
C+ Goal FitB+ Strength of SupportD CoverageA+ Formula Quality

Iron can markedly improve brain fog and concentration when iron deficiency is the cause. It does not improve focus when iron status is already adequate and can be harmful if unnecessary.

The 25 mg bisglycinate amount is well absorbed and clearly disclosed. Use is best guided by iron and blood-count testing because excess iron can accumulate and cause gastrointestinal effects or organ damage.

Study evidence
Iron Adverse 33 studies

Ingredients

IngredientAmount per serving
Iron (Iron Bisglycinate Chelate)
25 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
B Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Iron bisglycinate chelate provides a gentle, highly absorbable 25 mg dose. One capsule is convenient, though no vitamin C or supportive B vitamins are included. The larger bottle keeps serving cost very low.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial.
    Waldvogel S; Pedrazzini B; Vaucher P; Bize R; Cornuz J; Tissot JD; Favrat B · BMC medicine · 2012
    Randomized trial154 participantsEnergy forIron
  2. Iron plays a certain role in patterned hair loss.
    Park SY; Na SY; Kim JH; Cho S; Lee JH · Journal of Korean medical science · 2014
    Case-control study420 participantsHair Health forIron
  3. Effects of iron supplementation in nonanemic pregnant women, infants, and young children on the mental performance and psychomotor development of children: a systematic review of randomized controlled trials.
    Szajewska H; Ruszczynski M; Chmielewska A · The American journal of clinical nutrition · 2010
    Systematic review561 participants5 studies pooledMental Focus forIron
  4. Intravenous iron versus blood transfusion for postpartum anemia: a systematic review and meta-analysis.
    Caljé E; Groom KM; Dixon L; Marriott J; Foon R; Oyston C; Bloomfield FH; Jordan V · Systematic reviews · 2024
    Meta-analysis4,196 participantsEnergy forIron
  5. Scientific Opinion on the substantiation of a health claim related to iron and maintenance of normal hair growth pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusHair Health forIron
  6. The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis.
    Falkingham M; Abdelhamid A; Curtis P; Fairweather-Tait S; Dye L; Hooper L · Nutrition journal · 2010
    Meta-analysisMental Focus forIron
  7. Iron deficiency, general health and fatigue: results from the Australian Longitudinal Study on Women's Health.
    Patterson AJ; Brown WJ; Powers JR; Roberts DC · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2001
    Cohort studyEnergy forIron
  8. Brain iron concentrations in the pathophysiology of children with attention deficit/hyperactivity disorder: a systematic review.
    Degremont A; Jain R; Philippou E; Latunde-Dada GO · Nutrition reviews · 2021
    Systematic review18 studies pooledMental Focus forIron
  9. A Hospital-based Study to Determine Causes of Diffuse Hair Loss in Women.
    Malkud S · Journal of clinical and diagnostic research : JCDR · 2015
    Observational study180 participantsHair Health forIron
  10. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  11. Iron status in diffuse telogen hair loss among women.
    Moeinvaziri M; Mansoori P; Holakooee K; Safaee Naraghi Z; Abbasi A · Acta dermatovenerologica Croatica : ADC · 2010
    Case-control study60 participantsHair Health forIron
  12. Cognitive Performance in Indian School-Going Adolescents Is Positively Affected by Consumption of Iron-Biofortified Pearl Millet: A 6-Month Randomized Controlled Efficacy Trial.
    Scott SP; Murray-Kolb LE; Wenger MJ; Udipi SA; Ghugre PS; Boy E; Haas JD · The Journal of nutrition · 2019
    Randomized trial140 participantsMental Focus forIron
  13. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  14. Effects of iron supplementation twice a week on attention score and haematologic measures in female high school students.
    Rezaeian A; Ghayour-Mobarhan M; Mazloum SR; Yavari M; Jafari SA · Singapore medical journal · 2015
    Randomized trial200 participantsMental Focus forIron
  15. Low iron stores: a risk factor for excessive hair loss in non-menopausal women.
    Deloche C; Bastien P; Chadoutaud S; Galan P; Bertrais S; Hercberg S; de Lacharrière O · European journal of dermatology : EJD · 2008
    Cross-sectional study5,110 participantsHair Health forIron
  16. Maternal Fatigue after Postpartum Anemia Treatment with Intravenous Ferric Carboxymaltose vs. Intravenous Ferric Derisomaltose vs. Oral Ferrous Sulphate: A Randomized Controlled Trial.
    Bombač Tavčar L; Hrobat H; Gornik L; Preložnik Zupan I; Vidmar Šimic M; Pečlin P; Kavšek G; Lučovnik M · Journal of clinical medicine · 2024
    Randomized trial300 participantsEnergy forIron
  17. Prenatal iron supplementation adjusted to maternal iron stores reduces behavioural problems in 4-year-old children.
    Iglesias-Vázquez L; Canals J; Hernández-Martínez C; Voltas N; Arija V · Maternal & child nutrition · 2023
    Randomized trial230 participantsMental Focus forIron
  18. Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
    Karakoyun Ö; Ayhan E; Yıldız İ · Journal of cosmetic dermatology · 2025
    Cohort study2,851 participantsHair Health forIron
  19. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  20. Iron Status, Anemia, and Iron Interventions and Their Associations with Cognitive and Academic Performance in Adolescents: A Systematic Review.
    Samson KLI; Fischer JAJ; Roche ML · Nutrients · 2022
    Systematic review50 studies pooledMental Focus forIron
  21. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forIron
  22. Hypophosphatemia attenuates improvements in vitality after intravenous iron treatment in patients with inflammatory bowel disease.
    Bjorner JB; Kennedy N; Lindgren S; Pollock RF · Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Randomized trial97 participantsEnergy forIron
  23. Effect of iron supplementation on cognition in Greek preschoolers.
    Metallinos-Katsaras E; Valassi-Adam E; Dewey KG; Lönnerdal B; Stamoulakatou A; Pollitt E · European journal of clinical nutrition · 2005
    Randomized trial49 participantsMental Focus forIron
  24. The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
    Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
    Case-control study100,203 participantsHair Health forIron
  25. Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration.
    Krayenbuehl PA; Battegay E; Breymann C; Furrer J; Schulthess G · Blood · 2011
    Randomized trial90 participantsEnergy forIron
  26. Associations between moderate alcohol consumption, brain iron, and cognition in UK Biobank participants: Observational and mendelian randomization analyses.
    Topiwala A; Wang C; Ebmeier KP; Burgess S; Bell S; Levey DF; Zhou H; McCracken C; Roca-Fernández A; Petersen SE; Raman B; Husain M; Gelernter J; Miller KL; Smith SM; Nichols TE · PLoS medicine · 2022
    Cohort study20,729 participantsMental Focus forIron
  27. Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
    Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
    Cohort study261 participantsHair Health forIron
  28. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  29. Longitudinal Development of Brain Iron Is Linked to Cognition in Youth.
    Larsen B; Bourque J; Moore TM; Adebimpe A; Calkins ME; Elliott MA; Gur RC; Gur RE; Moberg PJ; Roalf DR; Ruparel K; Turetsky BI; Vandekar SN; Wolf DH; Shinohara RT; Satterthwaite TD · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Cohort studyMental Focus forIron
  30. Alopecia Areata Different View; Heavy Metals.
    Ozaydin-Yavuz G; Yavuz IH; Demir H; Demir C; Bilgili SG · Indian journal of dermatology · 2024
    Case-control study61 participantsHair Health forIron
  31. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  32. Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
    Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
    Meta-analysis10,029 participants36 studies pooledHair Health forIron
  33. Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
    Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
    Cross-sectional study100 participantsHair Health forIron
  34. Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
    Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
    Cohort study155 participantsHair Health forIron
  35. The Effect of Iron-Fortified Lentils on Blood and Cognitive Status among Adolescent Girls in Bangladesh.
    Barnett AL; Wenger MJ; Yunus FM; Jalal C; DellaValle DM · Nutrients · 2023
    Randomized trial359 participantsMental Focus Productivity Boost forIron
  36. Randomised study of cognitive effects of iron supplementation in non-anaemic iron-deficient adolescent girls.
    Bruner AB; Joffe A; Duggan AK; Casella JF; Brandt J · Lancet (London, England) · 1996
    Randomized trial81 participantsMental Focus forIron
  37. Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials.
    Low M; Farrell A; Biggs BA; Pasricha SR · CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2014
    Meta-analysis7,089 participants32 studies pooledProductivity Boost forIron
  38. Consumption of Iron-Biofortified Beans Positively Affects Cognitive Performance in 18- to 27-Year-Old Rwandan Female College Students in an 18-Week Randomized Controlled Efficacy Trial.
    Murray-Kolb LE; Wenger MJ; Scott SP; Rhoten SE; Lung'aho MG; Haas JD · The Journal of nutrition · 2017
    Randomized trial150 participantsProductivity Boost forIron
  39. Functional consequences of iron supplementation in iron-deficient female cotton mill workers in Beijing, China.
    Li R; Chen X; Yan H; Deurenberg P; Garby L; Hautvast JG · The American journal of clinical nutrition · 1994
    Randomized trial80 participantsProductivity Boost forIron
  40. Daily iron supplementation for improving anaemia, iron status and health in menstruating women.
    Low MS; Speedy J; Styles CE; De-Regil LM; Pasricha SR · The Cochrane database of systematic reviews · 2016
    Meta-analysis8,506 participants67 studies pooledProductivity Boost forIron