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Bromelain 2400 GDU/g - 500 mg

NOW
4.7
★ ★ ★ ★ ★
(8036 ratings)
Bromelain 500 mg
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Score85
Clearly stated 2,400 GDU per gram activity and a substantial amount are major strengths; delivery and goal-specific timing remain the practical gaps.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Anti-Inflammatory Support
Digestive Health
Joint Health

Score 85

Clearly stated 2,400 GDU per gram activity and a substantial amount are major strengths; delivery and goal-specific timing remain the practical gaps.
How scoring works
$13.90($0.23 per serving)
Daily Vita
$ 13.90
iHerb
$ 14.68
Vitacost
$ 15.79
Amazon
$ 24.57
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Analysis

The 500 mg amount and 2,400 GDU per gram activity provide a well-characterized enzyme dose. Bromelain directly supports protein digestion and may also support short-term tissue-comfort pathways when used away from food.

A regular capsule does not provide the protection of an enteric-coated tablet. The supplied label data also do not say whether to take it with meals for digestion or between meals for systemic use.

The smaller bottle is well suited to a trial period. The formula remains narrow, so it does not address fiber, the microbiome, cartilage structure, or broader inflammatory pathways.

Who is it for
  • Adults who want a measurable bromelain dose
  • People seeking help digesting protein-rich meals
  • Users considering focused short-term tissue support
Best for
  • Protein digestion
  • Activity-standardized enzyme use
  • A simple single-ingredient routine

Pros

  • High bromelain amount
  • Activity disclosed at 2,400 GDU per gram
  • No unrelated active ingredients

Cons

  • No enteric coating
  • Meal timing is not provided
  • Single-enzyme coverage is narrow

Warnings

  • Bromelain may increase bruising or bleeding when combined with anticoagulant or antiplatelet medicines.
  • People planning surgery should ask the surgical team when to stop bromelain because of its effect on bleeding tendency.
  • People with pineapple allergy may also react to pineapple-derived bromelain.

Nutrient quality

91 Highest impact

High-activity bromelain provides a strong standalone enzyme serving. Its potency is clear, but standard capsule delivery and missing meal timing limit systemic-use confidence.

Ingredient transparency

82 Highest impact

Listed active ingredients have specific amounts and no proprietary blend hides their doses. Bromelain activity, meal timing, full source details, or non-active ingredients remain incompletely disclosed.

Customer satisfaction

74 High impact

The aggregate rating is strong and is supported by a very large review sample. No review comments are supplied, so recurring complaints and fit with the intended use cannot be checked.

Value for money

92 Highest impact

The effective serving offers strong value relative to formula quality. A focused or coherent ingredient list supports efficient spending.

Report analysis

Goals

Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA+ Formula Quality

High-activity bromelain is well aligned with short-term swelling and tissue-comfort support. The disclosed enzyme potency and substantial amount make its contribution easy to judge.

The focused formula offers strong depth for one proteolytic pathway but limited support for broad systemic inflammation. Missing empty-stomach directions leave an important practical detail unclear for systemic use.

Study evidence
Bromelain Supportive 12 studies
Digestive Health
Impact
Highest effect
B Goal FitA+ Strength of SupportD+ CoverageA+ Formula Quality
Bromelain · 500 mg

Bromelain directly supports protein digestion and is supplied with a clearly stated activity standard. It is a focused enzyme rather than a broad gut-health formula.

The 500 mg amount at 2,400 GDU per gram provides a meaningful and assessable contribution. Bromelain may increase bruising or bleeding risk when combined with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Supportive 2 studies
Joint Health
Impact
High effect
C+ Goal FitA- Strength of SupportC- CoverageA+ Formula Quality

A full-strength bromelain serving with declared 2400 GDU per gram activity offers focused support for joint-comfort pathways. Human evidence is promising but less established than for the leading structural and botanical joint ingredients.

The capsule lacks enteric protection and the supplied directions do not explain between-meal use for systemic effects. Bromelain may increase bleeding tendency in people using anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Mixed 5 studies

Ingredients

IngredientAmount per serving
Bromelain (Pineapple)
500 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
A Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyA+ Value

The label provides a strong standalone bromelain dose with clearly stated high enzyme activity. A standard capsule offers less protection for systemic use, and no meal-timing directions are included in the provided data. Cost efficiency is excellent for the amount of bromelain supplied, though the pineapple plant part is not identified.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  2. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  3. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  4. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  5. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  6. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  7. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  8. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  9. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  10. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  11. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  12. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain