$25.00 $0.41 per serving
Product analysis
5-HTP 50 mg is intended for mood and relaxation, but noticeable everyday benefits remain uncertain.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality20
The ingredient forms are unspecified, leaving their preparation quality uncertain. Ingredient names alone do not establish how well the mixture can be used.
Ingredient Transparency63
All ingredient amounts are listed, making serving comparisons possible. The forms are unspecified, so the preparations cannot be compared as precisely.
Value For Money19
The serving price offers poor value for 5-HTP and limited value for glycine. Value for vitamin B6 remains uncertain, making the combination hard to justify on cost alone.
Customer Satisfaction66
Early ratings are positive, but the small number of reviews limits confidence. A handful of opinions cannot establish a typical experience or health benefit.
Product Focus62
Mood and relaxation give the formula a recognizable purpose, but the expected effects remain uncertain. The small glycine amount adds little support for sleep quality.
- Format
Capsule - Container
- 60 Capsule(s)
- Per serving
- $0.41
- Customer rating
- 4.5 · 46 ratings
Goals
Impact
High effect
Vitamin B6 · 3 mg5-HTP · 50 mg
5-HTP is a serotonin precursor, but that role does not establish a noticeable mood benefit. The supplied older-adult study did not find a significant mood improvement over its control group. Clinical depression findings do not establish routine benefit in generally healthy adults. B6 is below the saved amount threshold.
How this product is rated for Mood Support
Ingredient fit76
The relevant ingredients contribute within the supplied amount and preparation comparisons. A matching amount does not establish routine mood benefit outside the populations described.
Goal fit
The relevant ingredients form a focused formula, although the product also addresses other goals.
Dose adequacy
The declared amounts provide partial to substantial matches to the supplied comparisons; these matches do not predict individual benefit.
Pathways19
The saved findings emphasize monoamine signalling. These routes describe ingredient relationships rather than demonstrated combined effects.
Depth
Neurotransmitter-related activity is the strongest represented route, without proving a noticeable mood effect.
Breadth
No route reaches the saved breadth threshold, so the contribution remains narrow.
Evidence94
The leading ingredient determines the strongest comparison, with population and preparation limits shaping what mood benefits can be expected.
Evidence strength
5-HTP leads the supplied comparison, although the supplied controlled mood findings do not establish routine benefit.
Studied preparation
The saved findings accept the counted preparations, but that does not extend clinical or preparation-specific results to every healthy user.
Formulation logic100
No missing required partner or listed ingredient conflict limits the counted contributions. Meeting the amount threshold does not prove a noticeable benefit.
Partner coverage
The counted ingredients can contribute without a missing required partner; this does not establish an added benefit from combining them.
Conflicts
No ingredient combination matched the supplied conflict checks.
Effective doses
The counted ingredients meet the saved minimum amount threshold, which is a comparison rule rather than a proven effective dose.
Impact
Moderate effect
Glycine · 220 mg
5-HTP may offer a narrow precursor link to sleep, but its likely role at 50 mg is limited and the product has no direct sleep-timing ingredient. Glycine and vitamin B6 are also present, but their amounts add little to sleep support.
The 220 mg of glycine is far below amounts associated with a possible sleep-quality contribution, and B6's normal role in the body doesn't establish that extra B6 improves sleep. The formula's potential therefore rests mainly on 5-HTP, whose sleep role remains uncertain.
How this product is rated for Sleep Support
Ingredient fit76
5-HTP is the main sleep-related ingredient; the small glycine amount adds little, and B6 doesn't establish a separate sleep benefit.
Goal fit
5-HTP is the only meaningful sleep-oriented active; glycine adds little at its listed amount, and B6 has no established sleep role.
Dose adequacy
The 50 mg 5-HTP amount offers a limited potential contribution; 220 mg glycine adds little, and 3 mg B6 doesn't establish sleep benefit.
Pathways40
The product's potential centers on the serotonin-melatonin precursor route, without a separate timing or calming role.
Depth
5-HTP points to precursor activity, but the product doesn't address sleep timing or direct calming.
Breadth
The formula centers on one precursor route, without another distinct sleep process receiving similar support.
Evidence58
5-HTP has a limited, population-specific connection to sleep; the other amounts don't establish additional sleep benefit.
Evidence strength
5-HTP has a narrower sleep connection than melatonin and doesn't establish a general benefit for adults.
Studied preparation
5-HTP is named, while the product doesn't identify a special preparation that broadens its sleep role.
Formulation logic100
The ingredients don't create a supported added benefit together; 5-HTP supplies the main potential sleep contribution.
Partner coverage
No ingredient partner is shown to add a separate sleep benefit to 5-HTP here.
Conflicts
No ingredient combination is identified as conflicting with sleep.
Effective doses
The 5-HTP amount carries the main potential; glycine adds little, and B6's presence doesn't establish a sleep contribution.
Impact
Moderate effect
Glycine · 220 mgVitamin B6 · 3 mg
5-HTP may help with some anxiety or stress-related symptoms, but whether it offers reliable everyday relief remains unclear. Its possible contribution is conditional, so the presence of 5-HTP alone is not a reason to expect broad or lasting relief.
How this product is rated for Stress Relief
Ingredient fit76
5-HTP is the ingredient with a direct, though conditional, stress-related role. The serving contains 50 mg of 5-HTP, matching the lower 50 mg comparison amount.
Goal fit
5-HTP is the ingredient with a direct, though conditional, stress-related role.
Dose adequacy
The serving contains 50 mg of 5-HTP, matching the lower 50 mg comparison amount.
Pathways13
5-HTP’s relevance centers on mood-related chemical signaling, with a smaller sleep-related connection.
Depth
5-HTP’s relevance centers on mood-related chemical signaling, with a smaller sleep-related connection.
Breadth
The possible contribution is concentrated in mood-related functions rather than broad stress relief.
Evidence56
5-HTP has conditional anxiety and stress-related applicability; everyday benefit remains uncertain. 5-HTP is identified, but its identity alone does not guarantee everyday relief.
Evidence strength
5-HTP has conditional anxiety and stress-related applicability; everyday benefit remains uncertain.
Studied preparation
5-HTP is identified, but its identity alone does not guarantee everyday relief.
Formulation logic100
The declared 5-HTP amount allows comparison; the smaller accompanying ingredients do not demonstrate added stress relief. No particular ingredient conflict is identified.
Partner coverage
No required ingredient partner is missing for the relevant ingredients.
Conflicts
No particular ingredient conflict is identified.
Effective doses
The declared 5-HTP amount allows comparison; the smaller accompanying ingredients do not demonstrate added stress relief.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin B6 | 3 mg | |
5-HTP | 50 mg | |
Glycine | 220 mg |
Glycine · 220 mg OverallScore48
Each serving provides 220 mg of glycine, a relatively small amount. The whole-product price works out to about $1.89 per gram of glycine, a relatively high cost on that basis.
How this ingredient is rated
Active Ingredient Quality & Bioavailability60
The saved facts record a good manufacturing practice claim; that alone does not establish glycine purity.
Glycine Sourcing and Purity Standards
The saved facts record a good manufacturing practice claim; that alone does not establish glycine purity.
Dose, Safety & Label Transparency46
The serving discloses 220 mg of glycine. Ordinary excipients are recorded.
Clinically Relevant Dosage
The serving contains 220 mg of glycine, a relatively small amount.
Label Transparency and Yield Disclosure
The glycine amount is individually disclosed as 220 mg per serving.
Clean Label and Excipient Quality
The saved facts record ordinary excipients; they do not establish that the complete ingredient list is minimal.
Value30
The whole-product price works out to about $1.89 per gram of glycine, a relatively high cost on that basis.
Cost Efficiency per 1,000mg of Glycine
The whole-product price works out to about $1.89 per gram of glycine, a relatively high cost on that basis.
5-HTP · 50 mg OverallScore48
Each capsule provides 50 mg of 5-HTP, with no botanical source identified in the saved facts. The whole-product price works out to about $0.83 per 100 mg of 5-HTP, which is relatively high in this comparison.
How this ingredient is rated
Active Ingredient Quality & Bioavailability40
The saved facts name 5-HTP but do not identify its botanical source.
Botanical Source & Standardization
The saved facts name 5-HTP but do not identify its botanical source.
Dose, Safety & Label Transparency79
A serving provides 50 mg of 5-HTP. The saved evaluation records a warning about serotonin-affecting medicines.
Dosage Potency & Range
A serving provides 50 mg of 5-HTP.
Safety Warnings & Label Clarity
The saved evaluation records a warning about serotonin-affecting medicines.
Value0
At about $0.83 per 100 mg of 5-HTP, the whole-product price is high in this comparison.
Price per 100mg 5-HTP
The whole-product price works out to about $0.83 per 100 mg of 5-HTP.
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Report alternatives
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
- Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
- Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
- High Dose Vitamin B6 Reduces Depression Symptoms.
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
- Associations of dietary B vitamins intakes with depression in adults.
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
- New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
- The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.