5-HTP (5-Hydroxytryptophan) 200 mg
Goals
$32.00 $0.53 per serving
Product analysis
5-HTP (5-Hydroxytryptophan) 200 mg centers on mood and sleep support, with good value for its main ingredient. Benefits remain uncertain for routine use, so the combination should not be expected to reliably improve mood or sleep.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality32
Ingredient quality is only partly clear because several forms are unspecified. The named 5-HTP source identifies its origin without establishing an absorption advantage.
Ingredient Transparency81
Every ingredient amount is stated, making the serving easier to compare. Forms are missing for glycine, taurine and inositol, leaving some differences between products unclear.
Value For Money52
Value is strongest for the main 5-HTP contribution. Glycine is relatively costly for the amount provided, while value for the remaining ingredients is uncertain.
Customer Satisfaction74
Customer feedback is very positive across a few hundred ratings. The review base offers some reassurance about satisfaction without establishing health effects.
Product Focus64
Mood and sleep are the main themes, but dependable benefits remain uncertain. The wider stress and weight-related uses have limited support for routine use.
- Format
Capsule - Container
- 60 Capsule(s)
- Per serving
- $0.53
- Customer rating
- 4.7 · 245 ratings
Goals
Impact
Highest effect
Vitamin B6 · 2 mg5-HTP · 200 mg
Impact
Moderate effect
Glycine · 100 mgVitamin B6 · 2 mg
Impact
Moderate effect
Impact
Moderate effect
Glycine · 100 mg
Taurine Not classified
No linked studies yet.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Niacin (Vitamin B3) | 20 mg | |
Vitamin B6 (Pyridoxine Hydrochloride) | 2 mg | |
5-HTP (Griffonia simplicifolia Seed Extract) | 200 mg | |
Glycine | 100 mg | |
Taurine | 100 mg | |
Inositol | 100 mg |
5-HTP (Griffonia simplicifolia Seed Extract) · 200 mg OverallScore82
Each serving provides 200 mg of 5-HTP. The cost per 100 mg of 5-HTP is relatively low. Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown. The label includes a warning about interactions with serotonin-modulating medication.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown.
Botanical Source & Standardization
Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown.
Dose, Safety & Label Transparency93
Each serving provides 200 mg of 5-HTP. The label includes a warning about interactions with serotonin-modulating medication.
Dosage Potency & Range
Each serving provides 200 mg of 5-HTP.
Safety Warnings & Label Clarity
The label includes a warning about interactions with serotonin-modulating medication.
Value85
The cost per 100 mg of 5-HTP is relatively low.
Price per 100mg 5-HTP
The cost per 100 mg of 5-HTP is relatively low.
Glycine · 100 mg OverallScore48
A serving provides 100 mg of glycine. The cost per gram of glycine is high. The product carries a GMP manufacturing claim, but no specific glycine grade is stated.
How this ingredient is rated
Active Ingredient Quality & Bioavailability60
The product carries a GMP manufacturing claim, but no specific glycine grade is stated.
Glycine Sourcing and Purity Standards
The product carries a GMP manufacturing claim, but no specific glycine grade is stated.
Dose, Safety & Label Transparency46
The glycine amount is stated as 100 mg per serving. Ordinary excipients or capsule materials are listed.
Clinically Relevant Dosage
The serving provides 100 mg of glycine.
Label Transparency and Yield Disclosure
The glycine amount is stated as 100 mg per serving.
Clean Label and Excipient Quality
Ordinary excipients or capsule materials are listed.
Value30
The cost per gram of glycine is high.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is high.
Taurine · 100 mg OverallScore55
A serving provides 100 mg of taurine, with a high estimated cost per gram. The estimate assigns the whole formula cost to taurine and may overstate it. The taurine source is not specified. Testing or GMP production is claimed, but no specific third-party seal is identified.
How this ingredient is rated
Active Ingredient Quality & Bioavailability72
The label identifies L-taurine or free-form taurine, but no purity grade is specified. The taurine source and manufacturing origin are not specified. No artificial colors, flavors, sweeteners or harsh flow agents are indicated.
Chemical Form and Purity
The label identifies L-taurine or free-form taurine, but no purity grade is specified.
Sourcing and Branded Ingredients
The taurine source and manufacturing origin are not specified.
Formulation Cleanliness
No artificial colors, flavors, sweeteners or harsh flow agents are indicated.
Dose, Safety & Label Transparency54
Each serving provides 100 mg of taurine. Testing or GMP production is claimed, but no specific third-party seal is identified.
Taurine Dosage Potency
Each serving provides 100 mg of taurine.
Dose Disclosure
The taurine amount per serving is clearly stated.
Quality Assurance and Testing
Testing or GMP production is claimed, but no specific third-party seal is identified.
Value20
The estimated cost per gram of taurine is high. The estimate assigns the full formula cost to taurine, so it may overstate its cost.
Price per Gram of Taurine
The estimated cost per gram of taurine is high. The estimate assigns the full formula cost to taurine, so it may overstate its cost.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
- Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
- Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
- High Dose Vitamin B6 Reduces Depression Symptoms.
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
- Associations of dietary B vitamins intakes with depression in adults.
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
- New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
- The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.