RxOmega-3

RxOmega-3

Natural Factors4.7 (14,616 ratings)
Format:Softgel Quantity: 240 Softgel(s) · 240 servings
Goals
$44.77 $0.18 per serving

Product analysis

51 out of 100

RxOmega-3 provides marine omega-3 fats that may support blood-fat balance, with less certain everyday benefits for skin and inflammation. Conflicting fatty-acid declarations make it harder to judge the complete mix you are buying.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality21

The DHA is identified as an ethyl ester, but the complete fatty-acid mix remains uncertain. Named fish sources alone do not establish the quality of the finished oil.

Ingredient Transparency62

Most amounts are listed, but most ingredient forms are omitted. Conflicting DHA declarations and an unresolved EPA amount make the complete fatty-acid profile difficult to compare.

Value For Money40

Value for money cannot be established confidently for the omega-3 content. Uncertain individual fatty-acid amounts make a like-for-like comparison difficult.

Customer Satisfaction91

Customer feedback is very positive across a large number of ratings. That gives a broad picture of satisfaction, without establishing health effects.

Product Focus69

The clearest potential benefit concerns blood-fat balance, with more uncertain support for skin and inflammation. Individual fatty-acid amounts matter more than total oil weight when comparing these benefits.

Format
Softgel
Container
240 Softgel(s)
Per serving
$0.18
Customer rating
4.7 · 14,616 ratings
Report analysis

Goals

Cardiovascular Support
Impact
Highest effect
A- Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Fish Oil · 1170 mg

The declared DHA amount relates to triglyceride metabolism. Oral studies support triglyceride lowering, but the supplied study exposures were higher than these declared component amounts per serving. This is support for a blood-fat marker, with no established general prevention of cardiovascular events. EPA remains unresolved: a stored label claim conflicts with the ingredient inventory, so it was not counted.

How this product is rated for Cardiovascular Support

Ingredient fit85

Declared fatty-acid amounts drive the findings; oil carrier mass does not substitute for active EPA or DHA.
Goal fit
The relevant active ingredients are central to the formula, though it is linked to several goals.
Dose adequacy
The included declared amount meets the saved amount finding; this is not a proven benefit threshold.

Pathways60

The saved findings are strongest for triglyceride metabolism.
Depth
The strongest saved contribution concerns triglyceride metabolism. This describes a selected mechanism rather than demonstrated event prevention.
Breadth
Only triglyceride metabolism reaches the saved coverage criterion.

Evidence83

EPA and DHA evidence supports triglyceride-marker effects.
Evidence strength
The omega-3 evidence concerns triglyceride markers, with no automatic cardiovascular-event benefit.
Studied preparation
The included preparations meet the saved preparation finding; this does not imply identical effects across populations or superior forms.

Formulation logic100

Partner requirements are satisfied and no matched conflicts were recorded; minimum amount findings vary by ingredient.
Partner coverage
No unmet partner requirement was recorded for the included ingredients; this does not establish extra benefit from combining them.
Conflicts
No matched formulation conflict was recorded in the supplied assessment.
Effective doses
The included ingredients meet the saved minimum amount criterion; it is not a proven effective clinical dose.
Study evidence
Fish Oil Supportive 185 studies
Skin Health
Impact
Moderate effect
C+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Omega-3 · 630 mg

Omega-3 at 630 mg is connected with skin-barrier lipids in the saved assessment. The supplied human UV-challenge evidence used a specific purified EPA preparation, so broad omega-3 content provides uncertain support for routine skin improvement.

How this product is rated for Skin Health

Ingredient fit67

The saved assessment identifies 1 relevant ingredients, alongside 1 other actives. The product is linked to 3 goals. The counted amounts provide partial alignment with the saved benchmarks. Unknown amounts add no support.
Goal fit
The saved assessment identifies 1 relevant ingredients, alongside 1 other actives. The product is linked to 3 goals.
Dose adequacy
The counted amounts provide partial alignment with the saved benchmarks. Unknown amounts add no support.

Pathways19

The strongest saved coverage is in epidermal barrier lipids, with partial coverage. 0 of 3 target areas reaches the saved coverage threshold.
Depth
The strongest saved coverage is in epidermal barrier lipids, with partial coverage.
Breadth
0 of 3 target areas reaches the saved coverage threshold.

Evidence78

Omega-3 provides the strongest saved evidence contribution at a counted amount. The supplied evidence retains its population and preparation limits. The counted preparations match the saved research criteria.
Evidence strength
Omega-3 provides the strongest saved evidence contribution at a counted amount. The supplied evidence retains its population and preparation limits.
Studied preparation
The counted preparations match the saved research criteria.

Formulation logic100

The counted ingredients can contribute independently or have their required partner present. No configured ingredient conflict was found. 1 of 1 counted ingredients reach the saved minimum amount benchmark.
Partner coverage
The counted ingredients can contribute independently or have their required partner present.
Conflicts
No configured ingredient conflict was found.
Effective doses
1 of 1 counted ingredients reach the saved minimum amount benchmark.
Study evidence
Omega-3 Supportive 35 studies
Inflammation
Impact
Moderate effect
C Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Fish Oil · 1170 mg

EPA and DHA from fish oil may lower some inflammatory blood markers, but the response varies and doesn't guarantee a noticeable everyday benefit. The amounts of these fatty acids matter more than total oil weight. An unresolved individual amount shouldn't be treated as zero, and other omega-3 or fat amounts cannot automatically stand in for EPA and DHA.

How this product is rated for Inflammation

Ingredient fit65

EPA and DHA from fish oil may lower some inflammatory blood markers, but the response varies and doesn't guarantee a noticeable everyday benefit.
Goal fit
EPA and DHA from fish oil may lower some inflammatory blood markers, but the response varies and doesn't guarantee a noticeable everyday benefit.
Dose adequacy
Fish Oil supplies an undisclosed amount per serving.

Pathways12

The connection concerns inflammatory processes or blood markers; a noticeable symptom benefit remains uncertain.
Depth
The connection concerns inflammatory processes or blood markers; a noticeable symptom benefit remains uncertain.
Breadth
Different inflammatory processes do not automatically translate into broader everyday relief.

Evidence70

EPA and DHA from fish oil may lower some inflammatory blood markers, but the response varies and doesn't guarantee a noticeable everyday benefit.
Evidence strength
EPA and DHA from fish oil may lower some inflammatory blood markers, but the response varies and doesn't guarantee a noticeable everyday benefit.
Studied preparation
Preparation and health context matter; an ingredient name alone does not guarantee the same anti-inflammatory effect.

Formulation logic100

No particular conflict or missing required partner is identified. Ingredient amounts still need to be interpreted individually.
Partner coverage
No required additional partner is missing for the ingredients described.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Fish Oil supplies an undisclosed amount per serving.
Study evidence
Fish Oil Supportive 68 studies

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Polyunsaturated Fat
1 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate (Anchovy, Mackerel, Sardine)
1170 mg 44
Omega-3 Fatty Acids
630 mg 54
Docosahexaenoic Acid Ethyl Ester
200 mg 64
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 200 mg OverallScore64
C Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyB+ Value
The DHA is in ethyl ester form, but conflicting stored amounts leave the amount per serving unresolved. The evaluation estimates about $0.93 per gram using 200 mg, so the same quantity could cost less if the DHA amount is higher.
How this ingredient is rated

Active Ingredient Quality & Bioavailability64

The chemical form is established, and antioxidant protection is recorded. The oil is about 54% omega-3.
DHA Chemical Form & Bioavailability
The DHA is in ethyl ester form, which is generally less readily absorbed than triglycerides.
Oxidation Protection & Stability
A protective antioxidant is recorded in the saved label information.
Oil Concentration & Purity
The recorded 630 mg of omega-3s makes up about 54% of the 1170 mg of oil per serving.

Dose, Safety & Label Transparency56

The DHA amount is unresolved because stored amounts conflict. A qualifying certification claim is recorded.
DHA Absolute Dosage
Conflicting stored amounts leave the exact DHA amount per serving unresolved.
Purity & Heavy Metal Verification
The saved information records a qualifying certification claim; test results were not independently verified.
Ingredient Source Transparency
Fish oil is identified as the source.

Value80

The evaluation estimates about $0.93 per gram of DHA using 200 mg; conflicting amounts mean the same quantity could cost less.
Price per Gram of DHA
The evaluation estimates about $0.93 per gram of DHA using 200 mg; conflicting amounts mean the same quantity could cost less.
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
A serving contains 1,170 mg of fish oil. The saved information does not establish the individual EPA or DHA amounts, so the oil amount alone does not show how much of either is present.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

An ethyl-ester form is identified. A specific purification method is recorded without its name.
Omega-3 Molecular Form
The evaluation identifies the oil as an ethyl-ester form.
Purification & Filtration Method
The evaluation records a specific purification method, but its name is not included in the saved facts.
Third-Party Purity & Potency Verification
The saved information does not establish a third-party testing claim or certification.
Source & Sustainability
The evaluation recognizes a fish source; the saved facts do not name the fish species or a sustainability certification.

Dose, Safety & Label Transparency0

A serving contains 1,170 mg of fish oil, but the saved information does not establish the EPA and DHA amounts or their concentration.
Total Active Omega-3 Dose (EPA + DHA)
The EPA and DHA amounts for the selected serving are not established, so the combined amount remains unknown.
Omega-3 Potency & Concentration
EPA plus DHA concentration cannot be established without a supported combined amount for the serving.
EPA & DHA Individual Disclosure
The saved evidence does not establish unambiguous individual EPA and DHA amounts for the selected serving.
Oxidation Protection (Stabilizers)
The saved evidence does not establish a qualifying antioxidant for oxidation protection.

Value100

The evaluation estimates about $0.31 per gram of EPA plus DHA, although the individual serving amounts are not established.
Cost Per Gram of Active EPA + DHA
The evaluation estimates about $0.31 per gram of EPA plus DHA, although the individual serving amounts are not established.
Omega-3 · 630 mg OverallScore54
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
Each serving lists 630 mg of omega-3 in ethyl ester form. The evaluation estimates about $0.31 per gram of EPA plus DHA using the whole-product price, though separate EPA and DHA amounts are unavailable in the disclosure facts.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The omega-3 is in ethyl ester form. The available facts record an antioxidant alongside its source.
Molecular Form & Absorption Potential
The omega-3 is in ethyl ester form; the evaluation favors triglyceride forms for absorption.
Source Purity & Oxidative Protection
The available facts record an antioxidant and a qualifying source, but do not establish measured oil freshness.

Dose, Safety & Label Transparency15

The available facts do not permit a full EPA and DHA comparison, and the recorded testing claim does not establish qualifying verification.
EPA & DHA Label Specificity
The serving lists 630 mg of omega-3; separate EPA and DHA amounts are not established in the evaluated facts.
Active Ingredient Concentration
EPA plus DHA as a share of the oil cannot be determined from the available amounts.
Third-Party Purity Verification
A testing claim is recorded, but the facts do not establish a qualifying certification or an accessible test report.

Value100

The evaluated cost is about $0.31 per gram of EPA plus DHA, using the whole-product price.
Price per 1000mg of EPA+DHA
The evaluation estimates about $0.31 per gram of EPA plus DHA based on the whole-product price.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  2. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  5. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  6. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsInflammation forFish Oil
  7. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsInflammation forFish Oil
  8. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsInflammation forFish Oil
  9. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsInflammation forFish Oil
  10. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledInflammation forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3