Ultra Strength One-per-Day RxOmega-3

Ultra Strength One-per-Day RxOmega-3

Natural Factors4.9 (10,747 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 60 servings
Goals
$25.17 $0.41 per serving

Product analysis

52 out of 100

Ultra Strength One-per-Day RxOmega-3 is aimed at cardiovascular support, with DHA relevant to triglyceride levels. Its main appeal is omega-3 support, while some amount and form details remain unclear.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality21

The DHA form is not clearly disclosed, limiting direct preparation comparisons. Naming the source fish does not establish the oil’s molecular form.

Ingredient Transparency60

Most declared amounts are listed, and some composition detail is available. One amount is missing and most forms are unspecified, while another composition detail remains uncertain.

Value For Money40

A reliable comparison of value for the DHA content is unavailable. The usable amount and price information do not support a clear cost comparison.

Customer Satisfaction95

Customer feedback is very positive across many thousands of ratings. The extensive response gives a broad picture of satisfaction, without proving cardiovascular effects.

Product Focus75

The formula focuses on omega-3 support for related cardiovascular and skin uses. DHA has a connection to triglyceride lowering, but the full EPA contribution remains unresolved and specific clinical benefits cannot be assumed.

Format
Softgel
Container
60 Softgel(s)
Per serving
$0.41
Customer rating
4.9 · 10,747 ratings
Report analysis

Goals

Inflammation
Impact
Situational effect
D Ingredient FitF PathwaysF EvidenceB Formulation Logic
Fish Oil · 1425 mg
Study evidence
Fish Oil Supportive 68 studies
Cardiovascular Support
Impact
High effect
C Ingredient FitD- PathwaysB+ EvidenceA- Formulation Logic
Fish Oil · 1425 mg
Study evidence
Fish Oil Supportive 185 studies
Skin Health
Impact
High effect
A Ingredient FitD PathwaysB EvidenceA+ Formulation Logic
Omega-3 · 900 mg
Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per servingScore
Calories
15 Calorie(s)
Total Fat
1.5 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate (Anchovy, Mackerel, Sardine)
1425 mg 40
Omega-3 Fatty Acids
900 mg 54
Eicosapentaenoic Acid Ethyl Ester
600 mg
Docosahexaenoic Acid Ethyl Ester
300 mg 74
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 300 mg OverallScore74
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value
A serving provides 300 mg of DHA. The cost per gram of DHA is moderate. DHA is in ethyl ester form. A purity certification or pharmaceutical-grade claim is indicated, but the specific claim is not identified here.
How this ingredient is rated

Active Ingredient Quality & Bioavailability72

DHA is in ethyl ester form. The declared omega-3 content is about 63% of the oil.
DHA Chemical Form & Bioavailability
DHA is in ethyl ester form.
Oxidation Protection & Stability
An antioxidant is indicated, though its identity is not available here.
Oil Concentration & Purity
The declared omega-3 content is about 63% of the oil.

Dose, Safety & Label Transparency83

A serving provides 300 mg of DHA. A purity certification or pharmaceutical-grade claim is indicated, but the specific claim is not identified here.
DHA Absolute Dosage
A serving provides 300 mg of DHA.
Purity & Heavy Metal Verification
A purity certification or pharmaceutical-grade claim is indicated, but the specific claim is not identified here.
Ingredient Source Transparency
The source includes small fish or krill, though the specific source is not identified here.

Value60

The cost per gram of DHA is moderate.
Price per Gram of DHA
The cost per gram of DHA is moderate.
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB+ Value
The serving contains 1425 mg of fish oil, but its EPA and DHA amounts remain unclear. The estimated cost per gram of EPA and DHA is moderate. The oil is described as ethyl ester form.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

The oil is described as ethyl ester form. A specific purification method is claimed, but its name is not available here. The available information does not mention independent testing.
Omega-3 Molecular Form
The oil is described as ethyl ester form.
Purification & Filtration Method
A specific purification method is claimed, but its name is not available here.
Third-Party Purity & Potency Verification
The available information does not mention independent testing.
Source & Sustainability
A fish source is indicated, but the species is not clear in the available information.

Dose, Safety & Label Transparency0

The combined EPA and DHA amount and their share of the oil are unclear. A qualifying antioxidant is not established in the available information.
Total Active Omega-3 Dose (EPA + DHA)
The combined EPA and DHA amount is unknown from the available information.
Omega-3 Potency & Concentration
The proportion of the oil supplied as EPA and DHA cannot be established.
EPA & DHA Individual Disclosure
Separate EPA and DHA amounts are not established in the available information.
Oxidation Protection (Stabilizers)
A qualifying antioxidant is not established in the available information.

Value80

The estimated cost per gram of EPA and DHA is moderate.
Cost Per Gram of Active EPA + DHA
The estimated cost per gram of EPA and DHA is moderate.
Omega-3 · 900 mg OverallScore54
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
The serving provides 900 mg of total omega-3. Its estimated EPA and DHA cost is low. Separate EPA and DHA amounts are incomplete, so their concentration is unknown. It uses ethyl esters.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The omega-3s are in ethyl ester form. The source and antioxidant information indicate antioxidant inclusion.
Molecular Form & Absorption Potential
The omega-3s are in ethyl ester form.
Source Purity & Oxidative Protection
The source and antioxidant information indicate antioxidant inclusion.

Dose, Safety & Label Transparency15

The total omega-3 amount is available, but separate EPA and DHA amounts are not both available. No qualifying independent purity certification or testing claim is available.
EPA & DHA Label Specificity
The total omega-3 amount is available, but separate EPA and DHA amounts are not both available.
Active Ingredient Concentration
The EPA and DHA share of the oil is unknown because the required amounts are incomplete.
Third-Party Purity Verification
No qualifying independent purity certification or testing claim is available.

Value100

The estimated cost per gram of EPA and DHA is low.
Price per 1000mg of EPA+DHA
The estimated cost per gram of EPA and DHA is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  2. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  5. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  6. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsInflammation forFish Oil
  7. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsInflammation forFish Oil
  8. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsInflammation forFish Oil
  9. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsInflammation forFish Oil
  10. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledInflammation forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3