B-50

B-50

NOW4.7 (3,985 ratings)
Format:Tablet Quantity: 250 Tablet(s) · 250 servings
Goals
$25.50 $0.10 per serving

Product analysis

69 out of 100

B-50 supplies B vitamins that help the body use energy from food and may help tiredness caused by low intake. Several ingredient forms are left unspecified, which makes it harder to compare the full formula with more clearly described alternatives.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Several vitamins have clearly identified forms, including B6 and B5. Folate, biotin, PABA and inositol remain less clear because their forms are unspecified.

Ingredient Transparency86

Amounts are stated across the formula, making serving comparisons possible. Several forms are missing, so the label does not fully describe every ingredient.

Value For Money58

The B6 and B2 portions offer good value, while B5 looks relatively costly for the amount supplied. Other ingredients have mixed or uncertain value, so the blend is less compelling if you only need one nutrient.

Customer Satisfaction88

Ratings are favorable across thousands of reviews. That gives a substantial picture of buyer satisfaction without proving an energy benefit.

Product Focus66

The formula is focused on energy use and metabolism, which are closely related roles of B vitamins. Extra vitamins do not establish an energy boost when intake is already adequate.

Format
Tablet
Container
250 Tablet(s)
Per serving
$0.10
Customer rating
4.7 · 3,985 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

Folate, Niacin, Vitamin B6, Vitamin B12, Vitamin B5 and Vitamin B2 (Riboflavin) can help reduce tiredness when inadequate intake causes deficiency-related fatigue. B12 and folate support normal red-blood-cell formation; deficiency-related anaemia can cause weakness. These functions do not establish an energy boost when intake is already adequate. The B12 amount falls below the saved comparison threshold, despite its nutritional role.

How this product is rated for Energy

Ingredient fit88

Vitamin B2 (Riboflavin) anchors the recognized ingredient fit, with declared amounts partly meeting the saved comparisons.
Goal fit
Recognized energy-related ingredients share the formula with ingredients serving other goals, reducing its focus.
Dose adequacy
The declared amounts partly meet the saved comparisons, limiting the size of the recognized contribution.

Pathways0

The saved result identifies no coverage of its specific energy pathways. Nutritional fatigue support remains distinct from alertness or exercise capacity.
Depth
No specific energy pathway receives coverage, even though the saved result recognizes nutritional contributions.
Breadth
No energy pathway reaches the saved breadth threshold.

Evidence78

Vitamin B2 (Riboflavin) leads the recognized evidence, but the supplied context limits how broadly its findings apply.
Evidence strength
Vitamin B2 (Riboflavin) supplies the strongest recognized evidence here, subject to the population and application limits described for it.
Studied preparation
The saved findings accept the qualifying preparations; this does not establish form superiority.

Formulation logic100

No required partner is missing, and no configured sedative conflict is present. The recognized amounts reach the saved minimum comparison.
Partner coverage
The recognized ingredients have no missing required partner for their assigned contributions.
Conflicts
No configured sedative conflict applies: valerian, kava, qualifying tryptophan and melatonin are absent.
Effective doses
All recognized ingredients reach the saved minimum amount comparison; that threshold is not proof of a clinical energy effect.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

B vitamins help the body use energy from food, with thiamin supporting carbohydrate metabolism and other B vitamins serving as enzyme helpers. These normal functions do not show that extra vitamins raise energy expenditure when intake is adequate.

How this product is rated for Metabolism Support

Ingredient fit81

The formula supplies nutrients involved in normal metabolism, with varied amounts and a broader focus than direct energy expenditure.
Goal fit
Recognized metabolic nutrients contribute to the saved finding, while other actives and the product’s broader uses reduce its focus on this goal.
Dose adequacy
Declared amounts provide partial coverage of the supplied comparisons, which do not establish doses that increase calorie expenditure.

Pathways0

The counted ingredients do not contribute to the evaluated direct energy-expenditure pathways.
Depth
No direct energy-expenditure pathway receives a contribution from the counted ingredients.
Breadth
No evaluated pathway reaches the supplied coverage threshold.

Evidence100

Evidence for normal nutrient functions supports the saved finding; it does not establish an extra metabolic boost when intake is adequate.
Evidence strength
Thiamin supplies the strongest saved evidence finding; normal carbohydrate metabolism does not demonstrate a further metabolic boost with adequate intake.
Studied preparation
The counted preparations match those recognized in the supplied comparison; this does not establish thermogenic benefit for the finished product.

Formulation logic100

No unmet partner requirement or specified conflict was identified. The counted ingredients meet the supplied minimum amount comparisons.
Partner coverage
The counted ingredients have no unmet partner requirement in the supplied findings; this does not establish additional benefit from combining them.
Conflicts
No specified ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the supplied minimum amount comparison, which is not a demonstrated threshold for increased calorie expenditure.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
50 mg 76
Riboflavin
50 mg 72
Niacin (Niacinamide)
50 mg 73
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (Calcium Pantothenate)
50 mg 70
Choline (Choline Bitartrate)
50 mg 61
PABA
50 mg 87
Inositol
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
PABA · 50 mg OverallScore87
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value
A serving lists 50 mg of PABA, with the amount stated individually. Scaled from the whole-product serving price, the cost is about $0.20 per 100 mg of PABA.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The saved facts identify PABA but do not record a pharmaceutical-grade or purity claim.
PABA Source & Grade
PABA is named, while no specific grade or purity designation is recorded in the saved facts.

Dose, Safety & Label Transparency95

The serving lists 50 mg of PABA. None of the three assessed additive categories are recorded.
PABA Dosage Alignment
The recorded PABA amount is 50 mg per serving.
Label Disclosure Clarity
The PABA amount is individually recorded as 50 mg per serving.
Additive and Excipient Quality
The evaluated facts record no FD&C dyes, titanium dioxide or hydrogenated oils.

Value85

The serving price corresponds to about $0.20 per 100 mg of PABA when scaled from the whole-product price.
Price per 100mg PABA
Based on the whole-product serving price, the equivalent cost is about $0.20 per 100 mg of PABA.
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
Each serving provides 50 mg of niacin. The price per serving is moderate for the niacin form. It uses niacinamide, a non-flushing form of niacin.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

It uses niacinamide, a non-flushing form of niacin.
Niacin Form & Goal Alignment
It uses niacinamide, a non-flushing form of niacin.
Precursor Source Quality
Niacinamide is the named form.

Dose, Safety & Label Transparency67

Each serving provides 50 mg of niacin. Niacinamide is a non-flushing form; no no-flush claim is recorded.
Clarity of Chemical Form
The label names niacinamide.
Form-Specific Dosage Efficacy
Each serving provides 50 mg of niacin.
Flush Risk & Safety Labeling
Niacinamide is a non-flushing form; no no-flush claim is recorded.

Value60

The price per serving is moderate for the niacin form.
Price Per Effective Serving
The price per serving is moderate for the niacin form.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
A serving contains 50 mg of vitamin B6, a high amount. The cost per amount of vitamin B6 is low. The B6 form is Pyridoxine Hydrochloride.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 form is Pyridoxine Hydrochloride. The listed ingredients do not include artificial colors, titanium dioxide or talc.
Vitamin B6 Form Identification
The B6 form is Pyridoxine Hydrochloride.
Clean Label and Excipient Purity
The listed ingredients do not include artificial colors, titanium dioxide or talc.

Dose, Safety & Label Transparency37

A serving contains 50 mg of vitamin B6, a high amount. The source is named.
Vitamin B6 Dose & Safety Policy
A serving contains 50 mg of vitamin B6, a high amount.
Label Transparency
The amount and chemical source are stated.

Value100

The cost per amount of vitamin B6 is low.
Vitamin B6 Price Efficiency
The cost per amount of vitamin B6 is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin