B-50

B-50

NOW4.7 (4,754 ratings)
Format:Tablet Quantity: 100 Tablet(s) · 100 servings
Goals
$11.60 $0.11 per serving

Product analysis

69 out of 100

B-50 supplies B vitamins that support normal use of food for energy, especially when intake is low. Some ingredient forms are omitted, making the exact preparations harder to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality58

Several B-vitamin forms are clearly identified, and calcium pantothenate is a favorable feature. Ordinary riboflavin is less favored, while the quality of some other ingredients remains uncertain.

Ingredient Transparency86

All ingredient amounts are listed, making quantities straightforward to check. Several forms are omitted, so the exact preparations are not fully clear.

Value For Money58

The serving cost is favorable for riboflavin and B6, but less appealing for B5 and thiamin. The remaining ingredients offer mixed or uncertain value.

Customer Satisfaction88

Customer feedback is highly positive across thousands of ratings. The large response count gives a broad picture of satisfaction.

Product Focus66

The clearest role is helping meet B-vitamin needs for normal energy use. Extra energy or a faster metabolism is not established when intake is already adequate.

Format
Tablet
Container
100 Tablet(s)
Per serving
$0.11
Customer rating
4.7 · 4,754 ratings
Report analysis

Goals

Impact
High effect
A- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin B5 · 50 mgRiboflavin · 50 mgThiamin · 50 mgVitamin B12 · 50 mcg

B vitamins help the body use food for energy, while folate and B12 support normal blood formation. Their contribution to tiredness is most relevant when intake is low or a deficiency is corrected; larger amounts do not establish extra energy when intake is adequate. B12 is present but its amount is below the saved inclusion requirement.

How this product is rated for Energy

Ingredient fit88

The relevant connection comes from Vitamin B2 (Riboflavin), Vitamin B1 (Thiamin), Vitamin B5, Folate, Vitamin B6, Niacin. The amounts offer different levels of support in the saved findings.
Goal fit
Relevant energy ingredients appear alongside ingredients aimed at other purposes, so the formulation has a broader focus.
Dose adequacy
The included amounts receive partial support against the saved amount references, without defining a proven fatigue-treatment dose.

Pathways0

The saved findings concern nutrient sufficiency rather than coverage of the configured alertness, muscle-energy, cellular-energy, stress-fatigue or blood-flow pathways.
Depth
No configured energy pathway receives coverage; nutrient-related contributions are considered separately.
Breadth
No configured pathway reaches the saved coverage requirement.

Evidence78

The strongest included evidence contribution comes from Vitamin B2 (Riboflavin). Studied-preparation matching does not remove the ingredient-specific limits on fatigue benefits.
Evidence strength
Vitamin B2 (Riboflavin) provides the strongest included evidence contribution; its population and deficiency limitations still determine the benefit that can be expected.
Studied preparation
The included amounts meet the saved studied-preparation check, without establishing that the finished product itself was tested.

Formulation logic100

The included ingredients meet the saved minimum amount requirement without a missing required partner or matched conflict.
Partner coverage
The included ingredients do not lack a required partner in the saved findings; this does not imply an added combination benefit.
Conflicts
No configured ingredient conflict was matched in the supplied facts.
Effective doses
All counted ingredients meet the saved minimum amount requirement; this is distinct from a proven effective fatigue-treatment dose.
Study evidence
Thiamin Disputed 12 studies
Impact
High effect
B+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Biotin · 50 mcgNiacin · 50 mgVitamin B12 · 50 mcgRiboflavin · 50 mgThiamin · 50 mgVitamin B5 · 50 mgVitamin B6 · 50 mg

B vitamins support the normal processes that turn food into usable energy. Their physiological roles and serving amounts do not establish a faster resting metabolic rate when intake is adequate. The supplied evidence therefore supports normal nutrient function rather than a demonstrated increase in whole-body energy expenditure.

How this product is rated for Metabolism Support

Ingredient fit81

The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.
Goal fit
The formula combines ingredients connected to metabolism with other actives, reducing its specific focus on energy expenditure.
Dose adequacy
The contributing amounts meet part of the saved comparison range, without establishing a proven thermogenic dose.

Pathways0

No contribution is established across the assessed energy-expenditure pathways.
Depth
No contribution is established across the assessed energy-expenditure pathways.
Breadth
No assessed pathway reaches the saved coverage threshold, leaving broad energy-expenditure support unestablished.

Evidence100

Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Evidence strength
Vitamin B1 (Thiamin) leads the saved evidence finding; its normal metabolic or biomarker roles do not establish a routine rise in energy expenditure.
Studied preparation
The contributing forms meet the saved preparation criteria; this does not transfer findings from other outcomes into a thermogenic benefit.

Formulation logic100

The contributing ingredients have no missing required partners or configured conflicts. Their amounts meet the saved minimum comparison threshold.
Partner coverage
No required partner is missing among contributing ingredients; this does not establish added thermogenesis from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied calculation.
Effective doses
All contributing ingredients meet the saved minimum amount threshold; this comparison threshold is not proof of a clinical thermogenic effect.
Study evidence
Biotin Supportive 5 studies
Niacin Supportive 17 studies
Thiamin Supportive 11 studies
Vitamin B6 Supportive 16 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
50 mg 76
Riboflavin
50 mg 72
Niacin (Niacinamide)
50 mg 73
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Biotin
50 mcg
Pantothenic Acid (Calcium Pantothenate)
50 mg 70
Choline (Choline Bitartrate)
50 mg 61
PABA
50 mg 87
Inositol
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
PABA · 50 mg OverallScore87
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value
A serving provides 50 mg of PABA. At the whole-product price, that works out to about $0.23 per 100 mg of PABA.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

PABA is identified by name; the saved facts do not record a pharmaceutical grade or purity designation.
PABA Source & Grade
PABA is identified by name; the saved facts do not record a pharmaceutical grade or purity designation.

Dose, Safety & Label Transparency95

A serving provides 50 mg of PABA.
PABA Dosage Alignment
The evaluation places 50 mg per serving in its B-complex amount category.
Label Disclosure Clarity
The saved facts record a separate amount of 50 mg PABA per serving.
Additive and Excipient Quality
The recorded ingredients show none of the evaluated artificial dyes, titanium dioxide or hydrogenated oils.

Value85

At the whole-product price, that works out to about $0.23 per 100 mg of PABA.
Price per 100mg PABA
At the whole-product price, that works out to about $0.23 per 100 mg of PABA.
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
The 50 mg of vitamin B6 per serving comes at a low cost per amount of B6. It uses pyridoxine hydrochloride. The amount exceeds the European adult daily upper limit, before food or other supplements are counted.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 comes from pyridoxine hydrochloride. The listed ingredients show no artificial dyes, titanium dioxide, hydrogenated oils or talc.
Vitamin B6 Form Identification
The B6 comes from pyridoxine hydrochloride.
Clean Label and Excipient Purity
The listed ingredients show no artificial dyes, titanium dioxide, hydrogenated oils or talc.

Dose, Safety & Label Transparency37

The serving provides 50 mg of B6, above the European adult daily upper limit; total intake can also include food and other supplements.
Vitamin B6 Dose & Safety Policy
The serving provides 50 mg of B6, above the European adult daily upper limit; total intake can also include food and other supplements.
Label Transparency
The B6 source is named as pyridoxine hydrochloride.

Value100

The cost per amount of B6 is low.
Vitamin B6 Price Efficiency
The cost per amount of B6 is low.
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyC Value
Each serving provides 50 mg of niacin. The cost per serving is moderate. The form is Niacinamide.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The form is Niacinamide.
Niacin Form & Goal Alignment
The form is Niacinamide.
Precursor Source Quality
The named form is Niacinamide.

Dose, Safety & Label Transparency67

Each serving provides 50 mg of niacin. A flush-free claim is not recorded.
Clarity of Chemical Form
The form is Niacinamide.
Form-Specific Dosage Efficacy
Each serving provides 50 mg of niacin.
Flush Risk & Safety Labeling
A flush-free claim is not recorded.

Value60

The cost per serving is moderate.
Price Per Effective Serving
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy Metabolism Support forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Biotin and contribution to normal energy-yielding metabolism: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusMetabolism Support forBiotin
  17. Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
    Perry CA; West AA; Gayle A; Lucas LK; Yan J; Jiang X; Malysheva O; Caudill MA · The Journal of nutrition · 2015
    Clinical trial75 participantsMetabolism Support forBiotin
  18. Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in kermanshah in iran (2008-2009)
    Hemmati M, Babaei H, Abdolsalehei M · Oman Medical Journal · 2013
    Randomized trial70 participantsMetabolism Support forBiotin
  19. Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes
    César A Albarracin, Bobby C Fuqua, James L Evans, Ira D Goldfine · Diabetes/Metabolism Research and Reviews · 2008
    Randomized trial348 participantsMetabolism Support forBiotin
  20. Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia
    Cristina Revilla-Monsalve, Iván Zendejas-Ruiz, Sergio Islas-Andrade, Armida Báez-Saldaña, Miguel Angel Palomino-Garibay, Pedro Martín Hernández-Quiróz, Cristina Fernandez-Mejia · Biomedicine & Pharmacotherapy · 2006
    Randomized trial33 participantsMetabolism Support forBiotin