3-in-1 Joint Formula

3-in-1 Joint Formula

Irwin Naturals4.4 (1,208 ratings)
Format:Softgel Quantity: 90 Softgel(s) · 15 servings
Goals
$28.90 $1.92 per serving

Product analysis

46 out of 100

3-in-1 Joint Formula may offer modest support for joint comfort, though the evidence depends on particular ingredient preparations. Unclear preparation details make the likely benefit of this combination harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Most ingredient preparations are unspecified, limiting a clear comparison of quality. Part of the ingredient identity is also unclear, so the full combination cannot be judged confidently.

Ingredient Transparency67

Most amounts are stated, but preparation forms are largely unspecified. Most applicable composition details are available, with one part still unresolved.

Value For Money40

Potassium offers favourable value at the full serving cost, while folate is costly relative to its contribution. Value remains uncertain for most other ingredients, including omega-3.

Customer Satisfaction75

Customer feedback is positive. More than a thousand ratings provide a substantial base for judging satisfaction.

Product Focus45

Some joint ingredients have modest comfort findings, but those findings depend on particular preparations. The broad mixture and unclear individual preparations limit how confidently they apply to this formula.

Format
Softgel
Container
90 Softgel(s)
Per serving
$1.92
Customer rating
4.4 · 1,208 ratings
Report analysis

Goals

Joint Health
Impact
High effect
C Ingredient FitB- PathwaysD+ EvidenceA Formulation Logic
Omega-3 · 1035 mgBoswellia · 115 mg
Study evidence
Boswellia Supportive 24 studies
Curcumin Supportive 62 studies
Ginger Supportive 23 studies
Manganese Supportive 3 studies
Omega-3 Supportive 40 studies
Sulfur Supportive 9 studies
Inflammation
Impact
Situational effect
F Ingredient FitF PathwaysF EvidenceC+ Formulation Logic
Fish Oil · 3180 mgVitamin E · 10 mgBoswellia · 115 mg
Study evidence
Boswellia Supportive 19 studies
Fish Oil Supportive 68 studies
Flax Supportive 35 studies
Ginger Supportive 30 studies
Vitamin E Supportive 20 studies
Cardiovascular Support
Impact
High effect
C- Ingredient FitB PathwaysA- EvidenceA+ Formulation Logic
Potassium · 250 mgFish Oil · 3180 mgVitamin B12 · 120 mcgVitamin E · 10 mgFolate · 225 mcgNiacin · 23 mg
Study evidence
Fish Oil Supportive 185 studies
Flax Supportive 103 studies
Folate Supportive 93 studies
Niacin Supportive 136 studies
Potassium Supportive 117 studies
Vitamin E Mixed 79 studies
Skin Health
Impact
High effect
C- Ingredient FitD PathwaysB EvidenceA+ Formulation Logic
Vitamin E · 10 mgOmega-3 · 1035 mg
Study evidence
Flax Supportive 7 studies
Niacin Supportive 61 studies
Omega-3 Supportive 35 studies
Vitamin E Supportive 38 studies

Ingredients

IngredientAmount per servingScore
Calories
60 Calorie(s)
Total Fat
3.5 Gram(s)
Saturated Fat
1 Gram(s)
Cholesterol
15 mg
Total Carbohydrates
3 Gram(s)
Dietary Fiber
1 Gram(s)
Protein
3 Gram(s)
Vitamin E (D-Alpha-Tocopherol)
10 mg
Niacin (Niacinamide)
23 mg 64
Folate
382 mcg DFE 27
Folic Acid
225 mcg 27
Vitamin B12 (Cyanocobalamin)
120 mcg 19
Manganese (Manganese Gluconate)
7 mg 85
Sodium
95 mg
Potassium
250 mg 49
Fish Oils
3180 mg 26
Omega-3 Fatty Acids
1035 mg 31
Glucosamine Sulfate (Glucosamine Sulfate 2KCl)
1500 mg
Chondroitin Sulfate
1200 mg
Flaxseed Oil
150 mg
Methylsulfonylmethane
150 mg
Indian Frankincense gum resin extract
115 mg 80
Boswellic Acids
74.75 mg
Stinging Nettle leaf extract
70 mg 74
Phytosterols
0.56 mg
Turmeric root extract
40 mg 81
Curcuminoids
38 mg
Alpha-Lipoic Acid
5 mg
BioPerine Complex
6 mg
Bioperine (Black Pepper Fruit Extract)
0 NP
Ginger Rhizome Extract (Gingerols)
0 NP
Adults 18–50 Women
Report overview
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
Boswellia · 115 mg OverallScore80
A+ Composition And Label DisclosureA+ Composition And Label DisclosureF Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  2. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  5. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  6. Effect of flaxseed supplementation on blood pressure: a systematic review, and dose-response meta-analysis of randomized clinical trials.
    Li L; Li H; Gao Y; Vafaei S; Zhang X; Yang M · Food & function · 2023
    Meta-analysis2,427 participants33 studies pooledCardiovascular Support forFlax
  7. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients.
    Paschos GK; Magkos F; Panagiotakos DB; Votteas V; Zampelas A · European journal of clinical nutrition · 2008
    Randomized trial59 participantsCardiovascular Support forFlax
  8. Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women.
    Patade A; Devareddy L; Lucas EA; Korlagunta K; Daggy BP; Arjmandi BH · Journal of women's health (2002) · 2008
    Randomized trial55 participantsCardiovascular Support forFlax
  9. Effect of flaxseed on blood lipid level in hyperlipidemic patients.
    Torkan M; Entezari MH; Siavash M · Reviews on recent clinical trials · 2016
    Randomized trial70 participantsCardiovascular Support forFlax
  10. Effects of flaxseed on blood pressure, body mass index, and total cholesterol in hypertensive patients: A randomized clinical trial.
    Toulabi T; Yarahmadi M; Goudarzi F; Ebrahimzadeh F; Momenizadeh A; Yarahmadi S · Explore (New York, N.Y.) · 2022
    Randomized trial112 participantsCardiovascular Support forFlax
  11. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  12. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  13. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  14. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  15. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  16. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  17. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  18. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  19. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  20. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin