RxOmega-3

RxOmega-3

Natural Factors4.7 (14,613 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 60 servings
Goals
$18.17 $0.30 per serving

Product analysis

51 out of 100

RxOmega-3 provides DHA, an omega-3 fat with limited support for healthy blood-fat levels. Unclear ingredient amounts and forms make it harder to compare the formula with other omega-3 supplements.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality21

The omega-3 ingredients are not described clearly enough for a confident quality comparison. DHA's form is not explicitly disclosed, despite a separate identification as an ethyl ester, so its absorption quality remains uncertain.

Ingredient Transparency62

Disclosure is uneven, with one ingredient amount and most forms unspecified. Some composition details are clear, but the complete omega-3 mixture remains uncertain.

Value For Money40

Value cannot be judged reliably from the available cost and ingredient information. In particular, the unclear DHA quantity prevents a dependable comparison of cost for the amount supplied.

Customer Satisfaction91

Customer feedback is strongly positive. The very large review base gives a broad picture of buyer satisfaction, without proving health benefits.

Product Focus69

The clearest purpose is omega-3 support for blood-fat levels. Skin and inflammation-related benefits are less certain, and the unresolved EPA amount limits expectations for the mixture.

Format
Softgel
Container
60 Softgel(s)
Per serving
$0.30
Customer rating
4.7 · 14,613 ratings
Report analysis

Goals

Cardiovascular Support
Impact
Highest effect
A- Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Fish Oil · 1170 mg

DHA is the main recognized connection to triglyceride support in this product. The supplied evidence used much higher purified DHA exposure; recognition here does not establish the same effect at this serving amount. EPA is mentioned in a source claim, but its presence and amount remain unresolved in the matching ingredient facts. Fish-oil carrier mass is not an additional active dose.

How this product is rated for Cardiovascular Support

Ingredient fit85

DHA declared active provides the main recognized connection. The recognized serving amounts reach the comparison references.
Goal fit
The recognized ingredients are focused on this goal, although the product is also linked to other uses.
Dose adequacy
Recognized serving amounts reach the saved comparison references, without establishing greater benefit from larger amounts.

Pathways60

The strongest recorded connection concerns triglyceride metabolism. The formula’s mechanism profile is narrow.
Depth
The strongest recorded connection concerns triglyceride metabolism; its ingredient-specific limits prevent interpreting this as proven clinical protection.
Breadth
Recorded coverage is concentrated on triglyceride metabolism, leaving the other mechanisms largely unrepresented.

Evidence83

DHA declared active leads the recognized evidence. The supplied evidence used much higher purified DHA exposure; recognition here does not establish the same effect at this serving amount.
Evidence strength
DHA declared active leads the recognized evidence. Population and exposure limits remain relevant.
Studied preparation
The saved finding recognizes the eligible preparations, without establishing finished-product equivalence or superior effects from a particular form.

Formulation logic100

No required partner is missing and no configured conflict was identified. The recognized ingredients meet the saved exposure threshold without implying added combination benefits.
Partner coverage
No required partner is missing for the recognized ingredients; this does not establish synergy.
Conflicts
No configured ingredient conflict was identified in the supplied facts; this is limited to the interactions evaluated.
Effective doses
All ingredients included in this finding meet the saved exposure threshold; it is not a proven clinical-effectiveness threshold.
Study evidence
Fish Oil Supportive 185 studies
Inflammation
Impact
Moderate effect
C Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Fish Oil · 1170 mg

Marine omega-3 fats may lower some inflammation-related markers in the blood. A change in these markers doesn’t guarantee relief from pain or other symptoms. DHA is confirmed here, but the EPA declaration remains unresolved, limiting what can be said about the complete EPA-and-DHA mixture.

How this product is rated for Inflammation

Ingredient fit65

Marine omega-3 fats may lower some inflammation-related markers in the blood.
Goal fit
Marine omega-3 fats may lower some inflammation-related markers in the blood.
Dose adequacy
DHA 600 mg. The serving amount alone doesn’t predict symptom relief.

Pathways12

EPA and DHA are related to fatty-acid signals that regulate inflammation.
Depth
EPA and DHA are related to fatty-acid signals that regulate inflammation.
Breadth
The ingredients don’t demonstrate broad relief through several distinct inflammatory processes.

Evidence70

Marine omega-3 fats may lower some inflammation-related markers in the blood.
Evidence strength
Marine omega-3 fats may lower some inflammation-related markers in the blood.
Studied preparation
Effects depend on the particular ingredient preparation; matching a name alone doesn’t guarantee symptom relief.

Formulation logic100

No particular conflict or missing ingredient partner is identified. A combination doesn’t automatically provide an additional anti-inflammatory effect.
Partner coverage
No required ingredient partner is identified as missing.
Conflicts
No particular ingredient conflict is identified.
Effective doses
DHA 600 mg. These amounts don’t by themselves establish routine symptom relief.
Study evidence
Fish Oil Supportive 68 studies
Skin Health
Impact
Moderate effect
C+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Omega-3 · 630 mg

The declared 630 mg omega-3 amount contributes to the skin-barrier aspect of the saved findings. Human UV-response evidence used specific EPA preparations, so expectations for routine benefits from a broader omega-3 product remain cautious.

How this product is rated for Skin Health

Ingredient fit67

The relevant ingredients provide a moderately focused skin contribution. The counted amounts provide partial overall dose support.
Goal fit
The relevant ingredients provide a moderately focused skin contribution.
Dose adequacy
The counted amounts provide partial overall dose support.

Pathways19

Skin-barrier lipids are the only assessed aspect, with partial coverage.
Depth
Skin-barrier lipids are the only assessed aspect, with partial coverage.
Breadth
No assessed skin aspect reaches the saved threshold for substantial coverage.

Evidence78

Omega-3 provides the strongest evidence contribution in the saved findings, with the preparation and nutritional context affecting applicability. The counted ingredients match preparations represented in the supplied evidence.
Evidence strength
Omega-3 provides the strongest evidence contribution in the saved findings, with the preparation and nutritional context affecting applicability.
Studied preparation
The counted ingredients match preparations represented in the supplied evidence.

Formulation logic100

No required partner is missing and no assessed conflict was identified. All counted ingredients pass the saved minimum amount check, although their support differs.
Partner coverage
No required supporting partner is missing for the counted ingredients.
Conflicts
No assessed ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients pass the saved minimum amount check, although their support differs.
Study evidence
Omega-3 Supportive 35 studies

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Fat
1 Gram(s)
Polyunsaturated Fat
1 Gram(s)
Cholesterol
5 mg
pharmaceutical grade Fish Oil concentrate (Anchovy, Mackerel, Sardine)
1170 mg 40
Omega-3 Fatty Acids
630 mg 54
Docosahexaenoic Acid Ethyl Ester
200 mg 54
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
DHA · 200 mg OverallScore54
C Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value
The DHA is in ethyl ester form, but conflicting stored amounts leave the amount per serving unresolved. The evaluation estimates about $1.51 per gram using 200 mg, so the same quantity could cost less if the DHA amount is higher.
How this ingredient is rated

Active Ingredient Quality & Bioavailability64

The chemical form is established, and antioxidant protection is recorded. The oil is about 54% omega-3.
DHA Chemical Form & Bioavailability
The DHA is in ethyl ester form, which is generally less readily absorbed than triglycerides.
Oxidation Protection & Stability
A protective antioxidant is recorded in the saved label information.
Oil Concentration & Purity
The recorded 630 mg of omega-3s makes up about 54% of the 1170 mg of oil per serving.

Dose, Safety & Label Transparency56

The DHA amount is unresolved because stored amounts conflict. A qualifying certification claim is recorded.
DHA Absolute Dosage
Conflicting stored amounts leave the exact DHA amount per serving unresolved.
Purity & Heavy Metal Verification
The saved information records a qualifying certification claim; test results were not independently verified.
Ingredient Source Transparency
Fish oil is identified as the source.

Value30

The evaluation estimates about $1.51 per gram of DHA using 200 mg; conflicting amounts mean the same quantity could cost less.
Price per Gram of DHA
The evaluation estimates about $1.51 per gram of DHA using 200 mg; conflicting amounts mean the same quantity could cost less.
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB+ Value
A serving contains 1,170 mg of fish oil. The saved information does not establish the individual EPA or DHA amounts, so the oil amount alone does not show how much of either is present.
How this ingredient is rated

Active Ingredient Quality & Bioavailability60

An ethyl-ester form is identified. A specific purification method is recorded without its name.
Omega-3 Molecular Form
The evaluation identifies the oil as an ethyl-ester form.
Purification & Filtration Method
The evaluation records a specific purification method, but its name is not included in the saved facts.
Third-Party Purity & Potency Verification
The saved information does not establish a third-party testing claim or certification.
Source & Sustainability
The evaluation recognizes a fish source; the saved facts do not name the fish species or a sustainability certification.

Dose, Safety & Label Transparency0

A serving contains 1,170 mg of fish oil, but the saved information does not establish the EPA and DHA amounts or their concentration.
Total Active Omega-3 Dose (EPA + DHA)
The EPA and DHA amounts for the selected serving are not established, so the combined amount remains unknown.
Omega-3 Potency & Concentration
EPA plus DHA concentration cannot be established without a supported combined amount for the serving.
EPA & DHA Individual Disclosure
The saved evidence does not establish unambiguous individual EPA and DHA amounts for the selected serving.
Oxidation Protection (Stabilizers)
The saved evidence does not establish a qualifying antioxidant for oxidation protection.

Value80

The evaluation estimates about $0.50 per gram of EPA plus DHA, although the individual serving amounts are not established.
Cost Per Gram of Active EPA + DHA
The evaluation estimates about $0.50 per gram of EPA plus DHA, although the individual serving amounts are not established.
Omega-3 · 630 mg OverallScore54
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value
Each serving lists 630 mg of omega-3 in ethyl ester form. The evaluation estimates about $0.50 per gram of EPA plus DHA using the whole-product price, though separate EPA and DHA amounts are unavailable in the disclosure facts.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The omega-3 is in ethyl ester form. The available facts record an antioxidant alongside its source.
Molecular Form & Absorption Potential
The omega-3 is in ethyl ester form; the evaluation favors triglyceride forms for absorption.
Source Purity & Oxidative Protection
The available facts record an antioxidant and a qualifying source, but do not establish measured oil freshness.

Dose, Safety & Label Transparency15

The available facts do not permit a full EPA and DHA comparison, and the recorded testing claim does not establish qualifying verification.
EPA & DHA Label Specificity
The serving lists 630 mg of omega-3; separate EPA and DHA amounts are not established in the evaluated facts.
Active Ingredient Concentration
EPA plus DHA as a share of the oil cannot be determined from the available amounts.
Third-Party Purity Verification
A testing claim is recorded, but the facts do not establish a qualifying certification or an accessible test report.

Value100

The evaluated cost is about $0.50 per gram of EPA plus DHA, using the whole-product price.
Price per 1000mg of EPA+DHA
The evaluation estimates about $0.50 per gram of EPA plus DHA based on the whole-product price.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Marine Omega-3 Supplementation and Cardiovascular Disease: An Updated Meta-Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants.
    Hu Y; Hu FB; Manson JE · Journal of the American Heart Association · 2020
    Meta-analysis127,477 participants13 studies pooledCardiovascular Support forFish Oil
  2. Impact of omega-3 fatty acids on hypertriglyceridemia, lipidomics, and gut microbiome in patients with type 2 diabetes.
    Lu J; Liu R; Ren H; Wang S; Hu C; Shi Z; Li M; Liu W; Wan Q; Su Q; Li Q; Zheng H; Qu S; Yang F; Ji H; Lin H; Qi H; Wu X; Wu K; Chen Y; Xu Y; Xu M; Wang T; Zheng J; Ning G; Zheng R; Bi Y; Zhong H; Wang W · Med (New York, N.Y.) · 2025
    Randomized trial309 participantsCardiovascular Support forFish Oil
  3. A systematic review of fish-oil supplements for the prevention and treatment of hypertension.
    Campbell F; Dickinson HO; Critchley JA; Ford GA; Bradburn M · European journal of preventive cardiology · 2013
    Meta-analysis1,524 participants17 studies pooledCardiovascular Support forFish Oil
  4. Effects of fish oil-derived fatty acids on suboptimal cardiovascular health: A multicenter, randomized, double-blind, placebo-controlled trial.
    Zeng Q; Dong SY; Liu YP; Fu J; Shuai P; Zhao ZM; Li TX · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2017
    Randomized trial422 participantsCardiovascular Support forFish Oil
  5. Effect of High-Dose Marine Omega-3 Fatty Acids on Atherosclerosis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Sekikawa A; Cui C; Sugiyama D; Fabio A; Harris WS; Zhang X · Nutrients · 2020
    Meta-analysis6 studies pooledCardiovascular Support forFish Oil
  6. Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial.
    Song J; Hu M; Li C; Yang B; Ding Q; Wang C; Mao L · Food & function · 2018
    Randomized trial201 participantsInflammation forFish Oil
  7. Eicosapentaenoic acid supplementation alleviates pruritus, enhances skin moisture, and mitigates depression in maintenance hemodialysis patients.
    Lin YL; Wang CL; Chiang TI · Frontiers in nephrology · 2024
    Randomized trial60 participantsInflammation forFish Oil
  8. Lowering effects of fish oil supplementation on proinflammatory markers in hypertension: results from a randomized controlled trial.
    Yang B; Ren XL; Li ZH; Shi MQ; Ding F; Su KP; Guo XJ; Li D · Food & function · 2020
    Randomized trial77 participantsInflammation forFish Oil
  9. The effects of ω-3 fish oil emulsion-based parenteral nutrition plus combination treatment for acute paraquat poisoning.
    Meng Z; Dong Y; Gao H; Yao D; Gong Y; Meng Q; Zheng T; Cui X; Su X; Tian Y · The Journal of international medical research · 2019
    Randomized trial174 participantsInflammation forFish Oil
  10. Effects of Omega-3 Fatty Acid Intake in Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Liu R; Jiang J; Fu Z; Liu C; Yao L; Quan H · Journal of the American Nutrition Association · 2022
    Meta-analysis49 studies pooledInflammation forFish Oil
  11. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  12. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  13. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsSkin Health forOmega-3
  14. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  15. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3