Mood Support

Mood Support

NOW4.5 (9,082 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 45 servings
Goals

Product analysis

59 out of 100

Mood Support combines B vitamins with calming ingredients that may help stress-related tension. The combination of St. John’s wort and 5-HTP raises a concern about excessive serotonin activity, which matters when deciding whether this blend is suitable.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Vitamin B5 and manganese have favorable identified forms, and niacin’s form is clear. Several other forms are undisclosed or cannot be assessed confidently, limiting how much can be concluded about the blend’s quality.

Ingredient Transparency88

All active ingredient amounts are listed, allowing the blend’s serving sizes to be compared. Five ingredient forms are not disclosed, which makes it harder to identify exactly what each serving contains.

Value For Money38

Value is mixed, with favorable serving-price comparisons for valerian and manganese but weaker comparisons for several other ingredients. The amounts of 5-HTP and theanine are particularly costly, and value remains uncertain for much of the blend.

Customer Satisfaction85

Customer ratings are very positive, based on a substantial body of feedback. These ratings describe satisfaction and do not establish effectiveness or safety.

Product Focus61

The blend is aimed at mood, stress and sleep, with B vitamins adding basic nutritional support. Its many active ingredients make it less targeted, and the St. John’s wort and 5-HTP combination raises a serotonin-related interaction concern.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.30
Customer rating
4.5 · 9,082 ratings
Report analysis

Goals

Mood Support
Impact
High effect
B- Ingredient FitC PathwaysA+ EvidenceB+ Formulation Logic
Folate · 667 mcg DFEVitamin B6 · 10 mgVitamin B12 · 200 mcgMagnesium · 50 mg5-HTP · 20 mg
Study evidence
5-HTP Supportive 9 studies
Folate Supportive 84 studies
GABA Supportive 12 studies
Magnesium Supportive 60 studies
Theanine Supportive 12 studies
Valerian Supportive 17 studies
Vitamin B6 Supportive 19 studies
Zinc Supportive 43 studies
Stress Relief
Impact
High effect
B- Ingredient FitB+ PathwaysA- EvidenceB+ Formulation Logic
Magnesium · 50 mgFolate · 667 mcg DFEVitamin B12 · 200 mcgGABA · 250 mgVitamin B6 · 10 mgTheanine · 50 mg
Study evidence
5-HTP Supportive 18 studies
Folate Supportive 19 studies
GABA Supportive 6 studies
Magnesium Supportive 13 studies
Taurine Supportive 5 studies
Theanine Supportive 16 studies
Valerian Supportive 18 studies
Zinc Supportive 9 studies
Sleep Support
Impact
Moderate effect
D+ Ingredient FitD- PathwaysB+ EvidenceA+ Formulation Logic
Magnesium · 50 mgTheanine · 50 mg
Study evidence
5-HTP Supportive 1 study
GABA Supportive 4 studies
Magnesium Supportive 23 studies
Taurine Not classified

No linked studies yet.

Theanine Supportive 8 studies
Valerian Supportive 31 studies
Zinc Supportive 14 studies
Impact
Highest effect
B Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 200 mcgMagnesium · 50 mgTaurine · 125 mgZinc · 5 mg
Study evidence
Folate Supportive 80 studies
Magnesium Supportive 114 studies
Taurine No effect 3 studies
Zinc Supportive 60 studies

Ingredients

IngredientAmount per servingScore
Thiamine (Thiamine Hydrochloride)
2 mg
Niacin (Niacinamide)
25 mg 65
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
200 mcg 21
Pantothenic Acid (D-Calcium Pantothenate)
50 mg 70
Magnesium (Magnesium Oxide)
50 mg
Zinc (Zinc L-Methionine)
5 mg
Manganese (Manganese Amino Acid Chelate)
2 mg 78
St. John's Wort extract (Hypericin)
450 mg 100
Holy Basil extract (Ursolic Acid)
100 mg
Valerian
50 mg 88
5-HTP (Griffonia simplicifolia)
20 mg 48
GABA
250 mg 73
Taurine
125 mg 52
L-Theanine
50 mg 70
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
GABA · 250 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyD- Value
A serving provides 250 mg of GABA, and the whole-product serving cost is high. The production method is not specified. The Other Ingredients panel includes a flow agent, but its name is unavailable.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The label names GABA without a specific branded source.
GABA Source & Production Method
The label names GABA without a specific branded source.

Dose, Safety & Label Transparency93

A serving lists 250 mg of GABA. The Other Ingredients panel includes a flow agent, but its name is unavailable.
GABA Dosage Adequacy & Transparency
A serving lists 250 mg of GABA.
Label Purity & Excipient Quality
The Other Ingredients panel includes a flow agent, but its name is unavailable.

Value40

The whole-product cost per serving is high.
Price per Effective Dose
The whole-product cost per serving is high.
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
A serving supplies 2 mg of manganese at a moderate cost per serving. The source is manganese amino acid chelate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The manganese comes from manganese amino acid chelate.
Manganese Chemical Form
The manganese comes from manganese amino acid chelate.

Dose, Safety & Label Transparency86

The label states 2 mg of manganese per serving and names its source.
Manganese Dosage Efficacy & Safety
A serving provides 2 mg of manganese.
Elemental Weight Disclosure
The label states the manganese amount and its source.

Value80

The cost per serving is moderate.
Price per Serving vs. Median
The cost per serving is moderate.
Theanine · 50 mg OverallScore70
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
Each serving provides 50 mg of L-Theanine, at a very high cost per 100 mg when the full product price is used. That is a mild amount. No branded source or purity claim is specified in the available information.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The ingredient is specified as L-Theanine. No branded source or purity claim is specified in the available information.
Isomer Specificity (L-Theanine)
The ingredient is specified as L-Theanine.
Branded Forms & Purity Standards
No branded source or purity claim is specified in the available information.

Dose, Safety & Label Transparency86

The serving clearly states 50 mg of L-Theanine, a mild amount.
Theanine Dosage Efficacy
At 50 mg per serving, it provides a mild amount.
Label Transparency & Blends
The L-Theanine amount is individually stated as 50 mg per serving.

Value20

The full product cost per 100 mg of theanine is very high.
Price per 100mg L-Theanine
Using the full product price, the cost per 100 mg of theanine is very high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium
  7. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsEveryday Health forMagnesium
  8. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsEveryday Health forMagnesium
  9. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsEveryday Health forMagnesium
  10. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsEveryday Health forMagnesium
  11. Cognitive Effects of Taurine and Related Sulphur-Containing Amino Acids: A Systematic Review of Human Trials and Considerations for Plant-Based Dietary Transitions.
    Moore JA; Cousins AL; Taylor RMJ; Griffiths AR; Young HA · Foods (Basel, Switzerland) · 2026
    Systematic review244 participants8 studies pooledEveryday Health forTaurine
  12. Association between habitual dietary taurine intake and the risk of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.
    Zhang S; Xu X; Wang D; Gu Y; Wu H; Meng G; Zhang Q; Liu L; Borné Y; Niu K; Bai L · Food & function · 2026
    Cohort study16,699 participantsEveryday Health forTaurine
  13. Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials.
    Nie Z; Liu Y; Zhang M; Wu C; Cao Q; Xu J; Zheng Y; Min Z; Zhang W; Han S · Nutrition reviews · 2025
    Meta-analysis34 studies pooledEveryday Health forTaurine
  14. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsEveryday Health forVitamin B12
  15. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsEveryday Health forVitamin B12
  16. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsEveryday Health forVitamin B12
  17. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsEveryday Health forVitamin B12
  18. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsEveryday Health forVitamin B12
  19. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsEveryday Health forZinc
  20. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsEveryday Health forZinc