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(46 ratings)
Theanine 100 mg
Valerian 50 mg
Product Image
Score60
Branded theanine, saffron, magnesium, and diverse botanicals provide broad calming support. High cost, three capsules, and ambiguous marker disclosure sharply reduce value.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
Stress Relief
Brain Health
Mood Support
Sleep Support

Score 60

Branded theanine, saffron, magnesium, and diverse botanicals provide broad calming support. High cost, three capsules, and ambiguous marker disclosure sharply reduce value.
How scoring works
$50.34($1.67 per serving)
Vitacost
$ 50.34
Pure Formulas
$ 51.99
Report prices

Analysis

Three capsules provide 100 mg branded Suntheanine, 50 mg elemental magnesium from 500 mg magnesium malate, 30 mg saffron extract, and smaller amounts of lemon balm, passionflower, lavender, valerian, and magnolia. The formula covers several calming and mood-related pathways with individually listed weights.

Suntheanine offers strong source confidence, while saffron and magnolia add distinct support beyond common sleep herbs. Valerian at 50 mg is too low and undefined to contribute much, and the label appears to repeat saffron and magnolia marker amounts in a way that complicates interpretation.

Only 30 servings are provided, with three capsules and an exceptionally high daily cost. It fits users who specifically value the branded theanine and multi-botanical design rather than simple sleep support.

Who is it for
  • Adults seeking a premium calming capsules
  • Users whose needs match the disclosed ingredient amounts
  • People who can screen ingredient-specific medication and tolerance concerns
Best for
  • Comparing form, dose, and practical value
  • Goal-aligned supplement selection
  • Users who prefer a premium calming capsules

Pros

  • Uses branded Suntheanine
  • Includes saffron and magnolia
  • Adds magnesium malate
  • Lists each botanical amount

Cons

  • Very high serving cost
  • Requires three capsules
  • Only 30 servings
  • Valerian amount is only 50 mg
  • Some marker amounts are ambiguous

Warnings

  • The combined theanine, lemon balm, passionflower, lavender, valerian, saffron, and magnolia may cause drowsiness or next-day impairment
  • Saffron may add to antidepressant effects and deserves review with serotonin-modulating medicines
  • Magnolia and other calming herbs may compound alcohol or sedative medicines
  • Turmeric may increase bleeding concern with anticoagulant or antiplatelet medicines

Nutrient quality

67 High impact

Branded theanine, saffron, and magnolia markers improve form quality. Elemental magnesium and most botanicals are modest, creating more breadth than depth around the two strongest actives.

Ingredient transparency

79 High impact

Listed active ingredients have specific weights and no proprietary blend hides their doses. Complete use directions and a full other-ingredients list are not included in the supplied facts.

Customer satisfaction

59 Moderate impact

The supplied average rating is strong, and the small review sample limits confidence. No detailed comments are provided to assess repeated complaints or whether experiences match the intended use.

Value for money

26 Situational impact

Weak dose efficiency or high recurring cost limits practical value. Incomplete form, activity, or use details remain the main value trade-off.

Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
A- Goal FitB+ Strength of SupportB+ CoverageB+ Formula Quality
Magnesium · 500 mgTheanine · 100 mg

Branded Suntheanine and a clinically relevant saffron extract provide strong calm-focus and mood support. Magnesium plus lemon balm, passionflower, lavender, valerian, and magnolia broaden the relaxation pathways.

Several herbs are supplied at small amounts, including valerian, and elemental magnesium is modest. The formula is coherent but relies on many partially dosed calming ingredients rather than a few deep pathways.

Study evidence
Magnesium Supportive 13 studies
Theanine Supportive 16 studies
Valerian Supportive 18 studies
Brain Health
Brain Health
Impact
High effect
B+ Goal FitB+ Strength of SupportB- CoverageB- Formula Quality
Magnesium · 500 mg

Suntheanine, magnesium, saffron, lemon balm, and other calming botanicals target stress-related cognitive strain. The formula favors relaxation and emotional balance rather than memory or processing speed.

Theanine and saffron are meaningful, while several herbs are included at modest amounts. Branded sources and marker disclosure improve quality, but the broad calming stack has some overlap.

Study evidence
Magnesium Supportive 86 studies
Theanine Supportive 17 studies
Mood Support
Mood Support
Impact
High effect
B+ Goal FitB- Strength of SupportC+ CoverageB Formula Quality
Magnesium · 500 mg

Branded theanine and saffron provide the strongest direct mood-support actives, with magnesium and calming botanicals adding secondary support. Valerian, lemon balm, passionflower, and lavender are present at modest amounts.

The formula covers calm focus, mood regulation, mineral support, and sleep-related relaxation. Several low-dose botanicals make the blend broad, but the main branded actives keep it reasonably coherent.

Study evidence
Magnesium Supportive 60 studies
Theanine Supportive 12 studies
Valerian Supportive 17 studies
Sleep Support
Sleep Support
Impact
High effect
B+ Goal FitC Strength of SupportC+ CoverageB- Formula Quality
Magnesium · 500 mgTheanine · 100 mg

Branded theanine, magnesium, saffron, and several calming herbs create a broad bedtime relaxation strategy. The concept is sleep-specific, but many herbs appear at token levels.

Suntheanine is well identified at 100 mg, while elemental magnesium is only 50 mg and valerian is far below typical use. Missing standardization for several botanicals makes the crowded label stronger in breadth than depth.

Study evidence
Magnesium Supportive 23 studies
Theanine Supportive 8 studies
Valerian Supportive 31 studies
Cognitive Support
Cognitive Support
Impact
Moderate effect
C- Goal FitB- Strength of SupportC CoverageC- Formula Quality
Magnesium · 500 mgTheanine · 100 mg

Suntheanine, saffron, magnesium, and calming botanicals may reduce stress that interferes with cognition, but the formula is not directly focus-oriented. Suntheanine at 100 mg and saffron extract at 30 mg are meaningful, while 50 mg elemental magnesium and most herbs are modest.

The formula addresses calm attention and stress-related cognitive interference without strong cholinergic or circulation support. The calming stack is internally consistent, though valerian and other sedating herbs may work against daytime focus.

Study evidence
Magnesium Supportive 24 studies
Theanine Supportive 25 studies
Mental Focus
Mental Focus
Impact
Moderate effect
C- Goal FitB- Strength of SupportD+ CoverageD Formula Quality
Magnesium · 500 mgTheanine · 100 mg

Branded L-theanine provides credible calm-focus support, while magnesium and saffron may help reduce tension. Several additional herbs are more sedating than focus enhancing and may reduce alertness for some users.

The formula is better suited to relaxation than demanding cognitive work. Valerian, passionflower, lemon balm, lavender, and magnolia may cause drowsiness, so use before driving or other alertness-dependent tasks is not appropriate.

Study evidence
Magnesium Supportive 6 studies
Theanine Supportive 19 studies
Productivity Boost
Productivity Boost
Impact
Moderate effect
D Goal FitB- Strength of SupportD+ CoverageD- Formula Quality
Magnesium · 500 mgTheanine · 100 mg

Theanine, magnesium, saffron, and calming botanicals may reduce stress, but the heavily sedating direction can work against productivity. Theanine and some botanicals have human calming evidence, while the multi-herb stack lacks strong evidence for improved work performance.

The formula covers calm and stress response but omits alertness, cognitive precursors, and fatigue resistance. The ingredients share a relaxation strategy, but valerian, passionflower, lavender, and magnolia may promote drowsiness in some users.

Study evidence
Magnesium Supportive 10 studies
Theanine Supportive 5 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Malate)
 50 mg
Magnesium Malate
500 mg
Turmeric
116 mg
Suntheanine (L-Theanine)
 100 mg
Lemon Balm
54 mg
Passionflower
54 mg
Lavender
54 mg
Valerian
50 mg
Safr'Inside (Saffron Stigma Extract, Safranal)
 30 mg
Magnolia Bark Extract (Honokiol, Magnolia officinalis, Magnolol)
 12 mg
Adults 18–50 Kosher
Report overview
Theanine (L-Theanine) · 100 mg OverallScore90
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Suntheanine supplies a branded, high-purity form at a well-aligned amount. Magnesium, saffron, and several calming botanicals broaden relaxation support beyond theanine alone. The cost per active amount is high, but the branded source and substantial supporting formula improve the practical value.

View ingredientView products
Valerian · 50 mg OverallScore40
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value

An undefined valerian form prevents a meaningful potency assessment. The 50 mg amount is too low to provide meaningful valerian support. A token amount and undefined form create poor valerian-specific value.

View ingredientView products
Loading alternative details
87 Performance

L-Theanine 200 mg Double Strength

Swanson
Branded Suntheanine is supplied at a substantial, fully disclosed amount for calm attention and relaxation. The single-active formula is narrower than the original but provides clearer quality and avoids lightly dosed or incompletely standardized botanicals.
82 Performance

Valerian

Nature's Way
Whole valerian plus valerenic-acid-standardized extract provides a substantial and clearly specified sleep-focused formula. It omits theanine and supporting botanicals, while valerian may cause drowsiness or add to sedative medicines.
84 Performance

Suntheanine L-Theanine 125 mg

Natural Factors Stress-Relax
A substantial branded Suntheanine amount provides strong source assurance in a focused relaxation formula. It is easier to assess than a crowded blend but does not replace valerian or the other nighttime ingredients.
76 Budget

Valerian Root 450 mg

Best Naturals
A large labeled valerian amount and long supply provide a very low-cost sleep option without unrelated active ingredients. The amount appears inconsistent with the product name and lacks standardization, so label interpretation and next-day drowsiness deserve caution.
85 Budget

Double Strength L-Theanine 200 mg

NOW
A meaningful L-theanine amount provides focused calm and relaxation at much lower serving cost, with a small inositol addition. Generic sourcing offers less purity assurance than a branded form, and it does not replace valerian or other nighttime botanicals.
85 Budget

L-Theanine 200 mg

California Gold Nutrition
A clearly disclosed L-theanine amount provides a simple, lower-cost option for relaxation and stress-related focus. It lacks branded purity markers and does not provide valerian, hops, passionflower, or other sleep botanicals.
87 Value

L-Theanine 100 mg

California Gold Nutrition
Branded AlphaWave L-theanine provides a clearly disclosed amount at strong serving value for calm focus and relaxation. The single-active design omits valerian and other sleep botanicals, so it best fits users prioritizing theanine.
82 Value

Valerian Root 200 mg

Swanson Superior Herbs
Valerenic-acid-standardized extract plus valerian herb provides a substantial, well-specified sleep formula with favorable serving economics. It lacks theanine and may add to drowsiness from alcohol or sleep medicines.
78 Value

Sleep

NOW
Substantial valerian, hops, passionflower, and GABA provide a broad nighttime formula with every active amount visible and reasonable serving value. Botanical marker percentages remain unclear, and the combined calming ingredients may cause additive drowsiness.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effectiveness of Valerian on insomnia: a meta-analysis of randomized placebo-controlled trials.
    Fernández-San-Martín MI; Masa-Font R; Palacios-Soler L; Sancho-Gómez P; Calbó-Caldentey C; Flores-Mateo G · Sleep medicine · 2010
    Meta-analysis18 studies pooledSleep Support forValerian
  2. Efficacy and tolerability of valerian extract LI 156 compared with oxazepam in the treatment of non-organic insomnia--a randomized, double-blind, comparative clinical study.
    Ziegler G; Ploch M; Miettinen-Baumann A; Collet W · European journal of medical research · 2003
    Randomized trial202 participantsSleep Support forValerian
  3. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  4. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine
  5. Current Evidence on Common Dietary Supplements for Sleep Quality.
    Esquivel MK; Ghosn B · American journal of lifestyle medicine · 2025
    Narrative reviewSleep Support forTheanine
  6. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine
  7. Effect of Combined Ingestion of L-Theanine and L-Arginine for Short-Term Psychological Stress in Young Adults: A Randomized Placebo-Controlled Study.
    Furushima D; Sugiyama I; Nomura Y; Unno K; Yamada H · Journal of nutritional science and vitaminology · 2023
    Randomized trial120 participantsStress Relief forTheanine
  8. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  9. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledMood Support Productivity Boost forTheanine
  10. Antenatal magnesium sulfate and neuroprotection.
    Doyle LW · Current opinion in pediatrics · 2012
    Meta-analysis6,145 participants5 studies pooledBrain Health forMagnesium
  11. No. 376-Magnesium Sulphate for Fetal Neuroprotection.
    Magee LA; De Silva DA; Sawchuck D; Synnes A; von Dadelszen P · Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2020
    Guideline / consensus4,446 participantsBrain Health forMagnesium
  12. Magnesium Sulfate Before Preterm Birth for Neuroprotection: An Updated Cochrane Systematic Review.
    Shepherd ES; Goldsmith S; Doyle LW; Middleton P; Marret S; Rouse DJ; Pryde P; Wolf HT; Crowther CA · Obstetrics and gynecology · 2024
    Systematic review5,917 participants6 studies pooledBrain Health forMagnesium
  13. Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta-analysis and trial sequential analysis.
    Wolf HT; Huusom LD; Henriksen TB; Hegaard HK; Brok J; Pinborg A · BJOG : an international journal of obstetrics and gynaecology · 2020
    Meta-analysis5,917 participants6 studies pooledBrain Health forMagnesium
  14. Magnesium sulfate and fetal neuroprotection: overview of clinical evidence.
    Chollat C; Marret S · Neural regeneration research · 2020
    Narrative reviewBrain Health forMagnesium
  15. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  16. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  17. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledBrain Health Cognitive Support Mental Focus forTheanine
  18. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  19. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  20. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus.
    Doyle LW; Crowther CA; Middleton P; Marret S; Rouse D · The Cochrane database of systematic reviews · 2009
    Meta-analysis6,145 participants5 studies pooledCognitive Support forMagnesium
  21. Effects of magnesium valproate adjuvant therapy on patients with dementia: A systematic review and meta-analysis.
    Zhang C; Sun L; Sun H · Medicine · 2022
    Meta-analysis1,899 participants22 studies pooledCognitive Support forMagnesium
  22. Effects of magnesium supplementation on serum brain-derived neurotrophic factor levels and cognitive function in patients undergoing fluoxetine therapy for depression.
    Noor NJ; Syamsuddin S; Liaury K; Tawali S; Idris I; Azis I; Lisal ST · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsCognitive Support forMagnesium
  23. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsCognitive Support forMagnesium
  24. Could intraoperative magnesium sulphate protect against postoperative cognitive dysfunction?
    Hassan WF; Tawfik MH; Nabil TM; Abd Elkareem RM · Minerva anestesiologica · 2021
    Randomized trial80 participantsCognitive Support forMagnesium
  25. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  26. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  27. Relationship between Whole-Blood Magnesium and Cognitive Performance among Chinese Adults.
    Lu Z; He R; Zhang Y; Li B; Li F; Fu Y; Rong S · Nutrients · 2023
    Cross-sectional study1,006 participantsMental Focus forMagnesium
  28. Serum Magnesium and Cognitive Function Among Qatari Adults.
    Al-Ghazali K; Eltayeb S; Musleh A; Al-Abdi T; Ganji V; Shi Z · Frontiers in aging neuroscience · 2020
    Cross-sectional study1,000 participantsMental Focus forMagnesium
  29. Magnesium status and attention deficit hyperactivity disorder (ADHD): A meta-analysis.
    Effatpanah M; Rezaei M; Effatpanah H; Effatpanah Z; Varkaneh HK; Mousavi SM; Fatahi S; Rinaldi G; Hashemi R · Psychiatry research · 2019
    Meta-analysisMental Focus forMagnesium
  30. The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial.
    Hemamy M; Pahlavani N; Amanollahi A; Islam SMS; McVicar J; Askari G; Malekahmadi M · BMC pediatrics · 2021
    Randomized trial33 participantsMental Focus forMagnesium
  31. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsMental Focus Productivity Boost forMagnesium
  32. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsMental Focus Productivity Boost Stress Relief forTheanine
  33. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  34. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  35. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  36. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  37. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  38. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  39. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  40. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  41. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine
  42. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  43. Standardized Extract of Valeriana officinalis Improves Overall Sleep Quality in Human Subjects with Sleep Complaints: A Randomized, Double-Blind, Placebo-Controlled, Clinical Study.
    Chandra Shekhar H; Joshua L; Thomas JV · Advances in therapy · 2024
    Randomized trial80 participantsMood Support Sleep Support Stress Relief forValerian
  44. Chemotypic diversity and neuroactive potential of Valeriana jatamansi Jones: a systematic review on phytochemistry, pharmacology and standardisation challenges.
    Nisar S; Jan N; Hassan I; Andleeb L; Shabir PA · Natural product research · 2026
    Meta-analysis12 studies pooledMood Support forValerian
  45. Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis.
    Shinjyo N; Waddell G; Green J · Journal of evidence-based integrative medicine · 2021
    Meta-analysis6,894 participants60 studies pooledMood Support forValerian
  46. Assessment of Valeriana officinalis l. (Valerian) for Conscious Sedation of Patients During the Extraction of Impacted Mandibular Third Molars: A Randomized, Split-Mouth, Double-Blind, Crossover Study.
    Farah GJ; Ferreira GZ; Danieletto-Zanna CF; Luppi CR; Jacomacci WP · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · 2020
    Randomized trial20 participantsMood Support forValerian
  47. Effectiveness and safety of oral sedation in adult patients undergoing dental procedures: a systematic review.
    Araújo JO; Bergamaschi CC; Lopes LC; Guimarães CC; de Andrade NK; Ramacciato JC; Motta RHL · BMJ open · 2021
    Systematic review327 participants12 studies pooledMood Support Stress Relief forValerian
  48. Cross-sectional and longitudinal associations of magnesium intake and cognition in the Healthy Aging Longitudinal Study in Taiwan.
    Tao MH; Chuang SC; Wu IC; Chan HT; Cheng CW; Chen HL; Lee MM; Chang HY; Hsiung CA; Hsu CC · European journal of nutrition · 2024
    Cohort study5,663 participantsProductivity Boost forMagnesium
  49. Low levels of serum magnesium are associated with poststroke cognitive impairment in ischemic stroke patients.
    Tu X; Qiu H; Lin S; He W; Huang G; Zhang X; Wu Y; He J · Neuropsychiatric disease and treatment · 2022
    Cohort study327 participantsProductivity Boost forMagnesium
  50. Hypomagnesemia and Acute Cognitive Decline in Older Adults: An Evaluation of Clinical Practice and Cognitive Outcomes at a National Health Service (NHS) Trust in England.
    Lai XN; Sadhwani V; Ng WM; Gani A · Cureus · 2025
    Cohort study667 participantsProductivity Boost forMagnesium
  51. Magnesium Depletion Score as a Novel Predictor of Cognitive Impairment: A Population-Based Cross-Sectional Study From NHANES.
    Chen M; Xue R; Zhang M; Zhang J; Zheng J; Ye D; Sun J · Journal of the American Medical Directors Association · 2025
    Cross-sectional study2,768 participantsProductivity Boost forMagnesium
  52. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  53. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  54. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  55. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  56. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  57. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  58. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  59. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  60. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  61. Comparison the effect of valerian and gabapentin on RLS and sleep quality in hemodialysis patients: A randomized clinical trial.
    Hajizadeh I; Jamshidi M; Kazemi M; Kargar H; Sadeghi T · Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2023
    Randomized trial40 participantsSleep Support forValerian
  62. Effects of a Valerian-Hops Extract Combination (Ze 91019) on Sleep Duration and Daytime Cognitive and Psychological Parameters in Occasional Insomnia: A Randomized Controlled Feasibility Trial.
    Schicktanz N; Gerhards C; Schlitt T; Aerni A; Müggler E; de Quervain D; Papassotiropoulos A; Boonen G; Drewe J; Butterweck V · Brain and behavior · 2025
    Randomized trial40 participantsSleep Support forValerian
  63. Valerian for sleep: a systematic review and meta-analysis.
    Bent S; Padula A; Moore D; Patterson M; Mehling W · The American journal of medicine · 2006
    Meta-analysis1,093 participants16 studies pooledSleep Support forValerian
  64. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  65. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  66. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  67. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  68. Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial.
    Velasquez ACA; Tsuji M; Dos Santos Cordeiro L; Petinati MFP; Rebellato NLB; Sebastiani AM; da Costa DJ; Scariot R · Oral and maxillofacial surgery · 2024
    Randomized trial54 participantsStress Relief forValerian
  69. Effect of kava and valerian on human physiological and psychological responses to mental stress assessed under laboratory conditions.
    Cropley M; Cave Z; Ellis J; Middleton RW · Phytotherapy research : PTR · 2002
    Non-randomized trial54 participantsStress Relief forValerian
  70. Stress-induced insomnia treated with kava and valerian: singly and in combination.
    Wheatley D · Human psychopharmacology · 2019
    Single-arm trial24 participantsStress Relief forValerian