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Advanced Bone Support

Thorne
4.7
★ ★ ★ ★ ★
(1297 ratings)
Vitamin B6 20 mg
Calcium 300 mg
Boron 3 mg
Product Image
Score84
Premium calcium and magnesium forms, D3, boron, and active B vitamins create focused bone support. Elevated B6 and incomplete daily mineral coverage are the main trade-offs.
How scoring works
Quantity:120 Capsule(s) • (60 servings)
Goals:
General Health
Testosterone Support

Score 84

Premium calcium and magnesium forms, D3, boron, and active B vitamins create focused bone support. Elevated B6 and incomplete daily mineral coverage are the main trade-offs.
How scoring works
$29.00($0.48 per serving)
iHerb
$ 29.00
Amazon
$ 29.00
Vitacost
$ 30.29
Pure Formulas
$ 29.00
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Analysis

The formula provides 300 mg DimaCal calcium, 100 mg dimagnesium malate, 25 mcg vitamin D3, and 3 mg boron. These ingredients cover mineral intake, vitamin D support, and bone-related trace nutrition in well-specified forms.

P5P and methylcobalamin add active B-vitamin support, though vitamin B6 reaches 20 mg while folate remains modest. Calcium and magnesium make useful contributions but do not fully cover daily needs.

Two capsules per serving and 60 servings support a manageable routine. It fits adults seeking focused bone nutrients who can account for B6 and mineral intake from other products.

Who is it for
  • Adults seeking a focused bone-support supplement
  • People who prefer malate and DimaCal mineral forms
  • Users who want D3 and boron alongside calcium
Best for
  • Bone mineral support
  • Calcium and magnesium supplementation
  • Boron intake

Pros

  • Uses DimaCal calcium
  • Uses dimagnesium malate
  • Provides D3 and clearly dosed boron
  • Includes P5P and methylcobalamin

Cons

  • Provides 20 mg vitamin B6
  • Does not fully cover daily calcium or magnesium needs
  • Serving cost is relatively high

Warnings

  • Long-term intake of 20 mg vitamin B6 can add materially to nerve-symptom risk when combined with other B-complex products.

Nutrient quality

90 Highest impact

Well-regarded mineral and vitamin forms provide focused skeletal support. Useful amounts and the absence of filler keep the formula balanced.

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Ingredient transparency

83 Highest impact

Most active ingredients and their amounts are clearly listed. Daily directions, a complete excipient panel, and some form details are missing from the supplied data.

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Customer satisfaction

69 High impact

The aggregate rating is favorable and supported by solid feedback volume. Complaint-level experiences are unavailable, so repeated drawbacks and purpose fit remain uncertain.

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Value for money

89 Highest impact

The serving cost is reasonable for the documented nutrient coverage. Form, dose, or disclosure limitations keep value from standing out further.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitA- Strength of SupportB+ CoverageA Formula Quality
Folate · 166.6 mcg DFEVitamin B12 · 50 mcgVitamin D · 25 mcgMagnesium · 100 mgBoron · 3 mg

Calcium, magnesium malate, vitamin D3, and boron form a focused foundation for skeletal health. Active B6 and methylcobalamin add support for mineral use and normal metabolism.

The forms and amounts are clearly disclosed, including a validated chelated boron source and a favorable magnesium form. The formula is narrower than a multivitamin and lacks vitamin K, but it provides meaningful depth for the pathways it targets.

Study evidence
Boron Supportive 6 studies
Magnesium Supportive 114 studies
Vitamin D Supportive 115 studies
Testosterone Support
Testosterone Support
Impact
High effect
C+ Goal FitA Strength of SupportC- CoverageB Formula Quality
Magnesium · 100 mgVitamin D · 25 mcgBoron · 3 mg

Boron provides a relevant route to testosterone support. The disclosed amount appears meaningful for that focused role.

The formula remains narrow rather than comprehensive. The high vitamin B6 amount may cause nerve symptoms with prolonged use.

Study evidence
Boron Disputed 3 studies

Ingredients

IngredientAmount per serving
Vitamin D (Vitamin D3)
 25 mcg
Vitamin B6 (Pyridoxal 5-Phosphate)
 20 mg
Folate
166.6 mcg DFE
Vitamin B12 (Methylcobalamin)
 50 mcg
Calcium (DimaCal)
 300 mg
Magnesium (Albion DiMagnesium Malate)
 100 mg
Boron (Albion Bororganic)
 3 mg
Gluten Free Adults 18–50
Report overview
Vitamin B6 (Pyridoxal 5-Phosphate) · 20 mg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Active pyridoxal 5'-phosphate provides a metabolically ready B6 form. The 20 mg dose lies within the preferred range for metabolic and neurological support. The two capsules serving is practical, while value is favorable for an active-form formula at the listed serving cost.

View ingredientView products
Calcium (DimaCal) · 300 mg OverallScore83
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyD+ Value

DimaCal supplies a highly bioavailable calcium malate form, while the 300 mg amount supports general supplementation but may not cover high needs alone. The elemental amount is clear, and no artificial color, sweetener, or whitening agent appears in the supplied ingredients. The serving offers average value at its price level.

View ingredientView products
Boron (Albion Bororganic) · 3 mg OverallScore80
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Albion Bororganic supplies a premium chelated boron source with strong quality-control credentials. The 3 mg dose is clearly linked to the named form and fits the preferred range for regular use. Its cost per standard boron amount is expensive, though the validated source partly supports the premium.

View ingredientView products
Loading alternative details
83 Performance

Calcium Bone Maker Complex with MCH-Cal and VitaMK7

Doctor's Best
<p>Hydroxyapatite calcium, vitamin D3, MK-7, magnesium malate, boron, and trace minerals cover more bone pathways than the original. The three-capsule serving and an unclear zinc unit slightly reduce practical transparency.</p>
83 Performance

Cal/Mag Citrate

NaturesPlus
<p>Calcium citrate, magnesium citrate, and boron citrate provide uniformly favorable mineral forms with useful disclosed amounts. Vitamin D3 and vitamin B12 are omitted, making the formula narrower than the original despite its strong mineral quality.</p>
83 Performance

Nutra-Support Bone

Carlson
<p>Citrate minerals, vitamin D3, chelated zinc and manganese, and boron form a balanced bone-focused combination. The larger softgel serving is less convenient, but the ingredient forms are thoughtful and clearly aligned with skeletal support.</p>
77 Budget

Calcium Citrate Magnesium and Zinc

Kirkland Signature
<p>A much lower serving cost supplies calcium, vitamin D3, magnesium, zinc, and supporting minerals. Undisclosed mineral forms and low boron make quality less certain than the original malate-based formula.</p>
77 Budget

Calcium Magnesium plus Boron

Solgar
<p>A lower recurring cost retains calcium, magnesium, and boron with some citrate and gluconate forms. Carbonate and oxide weaken absorption quality, and taking the large calcium amount at once may be less efficient.</p>
85 Budget

BoneUp

Jarrow Formulas
<p>A lower-cost serving combines hydroxyapatite calcium with vitamin D, vitamin K2, magnesium, and trace minerals. Magnesium oxide and low boron are trade-offs, and vitamin K2 requires consistent intake for people using warfarin.</p>
85 Value

BoneUp

Jarrow Formulas
<p>Hydroxyapatite calcium, vitamin D, vitamin K2, magnesium, and trace minerals provide broad bone support at a lower serving cost. Magnesium oxide and low boron limit refinement, while vitamin K2 needs clinician-managed consistency for warfarin users.</p>
71 Value

Calcium Citrate Mini-Tablets

Rainbow Light
<p>Calcium citrate, vitamin D3, and boron glycinate provide a coherent bone-support base with favorable forms. The serving cost is not clearly lower than the original, and the large calcium amount would be better divided while small spirulina and horsetail additions add little.</p>
81 Value

Bone Restore

Life Extension
<p>Calcium, magnesium, vitamin D3, boron, zinc, and manganese provide broad bone-focused coverage with favorable stated value. Magnesium oxide and a calcium-heavy balance reduce mineral quality, and the serving cost is not clearly lower than the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  2. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  3. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  4. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  5. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  6. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  7. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  8. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  9. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  10. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  11. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  12. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  13. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  14. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  15. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  16. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  17. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  18. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron