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Cal/Mag Citrate

NaturesPlus
4.8
★ ★ ★ ★ ★
(1424 ratings)
Calcium 500 mg
Magnesium 250 mg
Boron 3 mg
Product Image
Score83
A lean, transparent calcium citrate, magnesium citrate, and boron formula with meaningful amounts. Missing D and K plus possible digestive effects are the main limitations.
How scoring works
Quantity:90 Capsule(s) • (30 servings)
Goals:
General Health
Bone Health
Digestive Health
Stress Relief
Heart Health
Energy
Testosterone Support
Joint Health
Cardiovascular Support

Score 83

A lean, transparent calcium citrate, magnesium citrate, and boron formula with meaningful amounts. Missing D and K plus possible digestive effects are the main limitations.
How scoring works
$12.28($0.40 per serving)
Vitacost
$ 12.45
Amazon
$ 14.45
Pure Formulas
$ 12.28
iHerb
$ 12.28
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Analysis

The three-capsule serving provides 500 mg calcium citrate, 250 mg magnesium citrate, and 3 mg boron citrate. All three ingredients are clearly disclosed and use practical forms for a focused bone and mineral formula.

The calcium-to-magnesium balance is reasonable, and citrate forms are generally easier to use than carbonate or oxide. The product does not include vitamin D or vitamin K, so those nutrients must come from diet or elsewhere when needed.

The formula fits adults seeking transparent calcium and magnesium without added vitamins or botanicals. Magnesium citrate may loosen stools, making divided dosing useful for sensitive users.

Who is it for
  • Adults seeking citrate-form calcium and magnesium
  • People who prefer a minimal ingredient list
  • Users who already cover vitamin D and K
Best for
  • Bone-mineral supplementation
  • Combined calcium and magnesium intake
  • Transparent citrate-based dosing

Pros

  • Uses calcium and magnesium citrate
  • Provides meaningful amounts of both minerals
  • Includes 3 mg boron citrate
  • Simple and fully disclosed formula
  • Good practical value

Cons

  • Does not include vitamin D
  • Does not include vitamin K
  • Requires three capsules
  • Magnesium citrate may affect tolerance

Warnings

  • Calcium and magnesium can reduce absorption of levothyroxine, bisphosphonates, and tetracycline-class antibiotics when taken together, so doses need separation.
  • Magnesium citrate may cause loose stools or abdominal cramping in sensitive users.
  • People with kidney disease should not use substantial calcium and magnesium supplements without clinical supervision.

Nutrient quality

92 Highest impact

Citrate forms are well understood and offer favorable absorption potential. Calcium, magnesium, and boron are each supplied at useful amounts.

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Ingredient transparency

80 High impact

Every listed active nutrient has a specific amount. The supplied data does not include a complete capsule and inactive ingredient list.

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Customer satisfaction

73 High impact

The aggregate satisfaction measure and review volume support a favorable first impression. Missing firsthand feedback leaves repeat complaints and real-world purpose fit uncertain.

.

Value for money

85 Highest impact

The moderate product cost is justified by favorable citrate forms and useful doses. Each serving provides good value for a focused three-mineral formula.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitA+ Strength of SupportB CoverageA+ Formula Quality
Magnesium · 250 mgBoron · 3 mg

Calcium citrate, magnesium citrate, and boron citrate provide clear, meaningful mineral support. The balanced amounts and related forms make the formula easy to assess.

Coverage centers on skeletal and neuromuscular health rather than every general-health pillar. Within that scope, each ingredient has a practical role and there is little label clutter.

Study evidence
Boron Supportive 6 studies
Magnesium Supportive 114 studies
Bone Health
Bone Health
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageA Formula Quality
Magnesium · 250 mgCalcium · 500 mgBoron · 3 mg

Calcium citrate and magnesium citrate supply well-balanced structural minerals, while boron adds a relevant trace-mineral pathway. All three amounts are clearly disclosed and use practical organic forms.

The focused combination has good depth for mineral support with little label padding. Vitamin D, vitamin K, and protein-matrix ingredients remain absent, preventing fully comprehensive coverage.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Digestive Health
Bowel Regularity
Digestive Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC- CoverageB+ Formula Quality
Magnesium · 250 mg

Magnesium citrate is well aligned with bowel regularity because it can support motility and draw water into the bowel. The clearly stated amount provides meaningful depth for that use.

Calcium and boron broaden the mineral purpose rather than digestive coverage, so the formula remains focused on one gut pathway. The concise, fully quantified label is a strength, although magnesium citrate may loosen stools more than desired in sensitive users.

Study evidence
Magnesium Supportive 50 studies
Stress Relief
Calm and Tension Relief
Stress Relief
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Magnesium · 250 mg

Magnesium directly supports nervous-system regulation and relaxation. Magnesium has established evidence when inadequate status contributes to stress symptoms.

The magnesium amount reaches a useful supplemental range. Magnesium citrate is clearly disclosed with a useful boron addition.

Study evidence
Magnesium Supportive 13 studies
Heart Health
Healthy Blood Pressure
Heart Health
Impact
Highest effect
B+ Goal FitA- Strength of SupportC- CoverageA Formula Quality
Magnesium · 250 mg

A meaningful magnesium citrate amount supports vascular tone, rhythm-related physiology, and cellular energy. The citrate forms are transparent and generally well absorbed, while the formula remains concise.

Calcium and boron make the design more bone focused, and no lipid, nitric-oxide, or homocysteine pathway is included. It offers focused mineral support rather than a comprehensive heart formula.

Study evidence
Magnesium Supportive 158 studies
Energy
Energy
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageA- Formula Quality
Magnesium · 250 mg

Magnesium at 250 mg meets the stated energy-support threshold and may help when inadequate mineral intake contributes to fatigue. Magnesium citrate is a clearly identified form with moderate absorption potential.

Calcium is supplied at twice the magnesium amount, keeping the product focused on mineral support rather than direct stimulation. Boron adds a small related mineral cofactor but does not create a separate energy mechanism.

Study evidence
Magnesium Supportive 4 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Citrate)
 500 mg
Magnesium (Magnesium Citrate)
 250 mg
Boron (Boron Citrate)
 3 mg
Gluten Free Adults 18–50 Vegan Dairy Free No Allergies Vegetarian
Report overview
Calcium (Calcium Citrate) · 500 mg OverallScore90
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Calcium citrate offers reliable absorption across a broad range of stomach-acid levels. The 500 mg serving is sized efficiently for a single dose. The favorable cost and clean supplied ingredient profile make it a practical option.

View ingredientView products
Magnesium (Magnesium Citrate) · 250 mg OverallScore75
D Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB Value
+2

Magnesium citrate provides moderate absorption with a clearly stated and well-aligned elemental dose. Boron adds useful bone-health synergy, while calcium remains at the acceptable ratio boundary. The modest serving cost makes the formula a sound value for users who want a combined mineral product.

View ingredientView products
Boron (Boron Citrate) · 3 mg OverallScore72
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Boron citrate provides a named organic form with a practical absorption profile. The clearly disclosed 3 mg dose fits common long-term supplementation targets. Value is limited compared with dedicated boron products because calcium and magnesium make up most of the formula.

View ingredientView products
Loading alternative details
81 Performance

Bone Restore

Life Extension
<p>Calcium, magnesium, vitamin D3, boron, zinc, and manganese broaden bone-focused support while retaining a meaningful boron amount. Magnesium oxide and a calcium-heavy balance make its mineral quality less consistent.</p>
80 Performance

Calcium Magnesium 1:1 Ratio

Bluebonnet
<p>Balanced calcium and magnesium use generally favorable citrate, malate, and aspartate forms. Boron is absent and the calcium-form split is unclear, but the larger mineral amounts may suit users seeking a broader major-mineral serving.</p>
85 Performance

Cal/Mag Caps

NaturesPlus
<p>Amino acid chelates provide balanced calcium and magnesium with strong form quality and straightforward dosing. The formula is narrower because it omits boron, but its major-mineral delivery is clear and focused.</p>
85 Budget

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a balanced two-mineral formula with stronger serving value. Boron is absent, but the core mineral forms and simple dosing are clear.</p>
86 Budget

Calcium & Magnesium Citrate Powder with Vitamin D3

NOW
<p>Calcium and magnesium citrate with vitamin D3 provide similarly favorable forms at a lower serving cost. The powder omits boron, but vitamin D adds a complementary bone-support nutrient.</p>
80 Budget

Calcium Mag & D Complex

Nature's Way
<p>Citrate, malate, and aspartate improve a useful calcium-magnesium blend at economical serving value. Carbonate and oxide lower average form quality, and boron is not included.</p>
82 Value

Calcium & Magnesium Mineral Complex

Nature's Way
<p>Magnesium bisglycinate and citrate plus calcium citrate and malate provide strong core forms at efficient serving value. Oxide and carbonate remain in the blend, while boron is absent.</p>
80 Value

Liquid Calcium Magnesium Citrate with Vitamin D3 Natural Strawberry Flavor

Solgar
<p>Citrate minerals and vitamin D3 form a coherent liquid with useful calcium and magnesium amounts and reasonable value. Duplicate vitamin D entries reduce clarity, and the formula does not provide boron.</p>
78 Value

Coral Calcium Plus

NOW
<p>Calcium, magnesium, and vitamin D provide a practical long-supply alternative at favorable serving value. Coral calcium, magnesium oxide, and missing boron make ingredient quality less consistent than the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  2. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  3. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  4. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  5. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  6. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  7. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  8. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  9. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  10. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  11. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  12. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  13. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  14. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  15. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  16. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  17. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  18. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  19. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  20. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  21. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  22. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  23. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  24. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  25. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  26. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  27. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  28. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  29. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  30. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  31. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  32. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  33. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  34. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  35. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  36. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  37. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  38. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  39. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  40. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  41. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  42. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  43. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  44. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  45. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  46. Essentiality of boron for healthy bones and joints.
    Newnham RE · Environmental health perspectives · 1995
    Randomized trial20 participantsJoint Health forBoron
  47. Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study
    Zbigniew Pietrzkowski, Michael J Phelan, Robert Keller, Cynthia Shu, Ruby Argumedo, Tania Reyes-Izquierdo · Clinical Interventions in Aging · 2014
    Randomized trial60 participantsJoint Health forBoron
  48. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis
    Romulus Scorei, Paul Mitrut, Iulian Petrisor, Iulia Scorei · Biological Trace Element Research · 2011
    Randomized trial60 participantsJoint Health forBoron
  49. Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis.
    Zeng C; Li YS; Wei J; Xie DX; Xie X; Li LJ; Gao SG; Luo W; Xiong YL; Xiao WF; Lei GH · Scientific reports · 2018
    Meta-analysis16 studies pooledJoint Health forMagnesium
  50. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
    Zeng C; Wei J; Terkeltaub R; Yang T; Choi HK; Wang YL; Xie DX; Hunter DJ; Zhang Y; Li H; Cui Y; Li LJ; Lei GH · Arthritis research & therapy · 2018
    Cross-sectional study13,947 participantsJoint Health forMagnesium
  51. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
    Shmagel A; Onizuka N; Langsetmo L; Vo T; Foley R; Ensrud K; Valen P · Osteoarthritis and cartilage · 2019
    Cohort study2,548 participantsJoint Health forMagnesium
  52. Associations of magnesium depletion score with the incidence and mortality of osteoarthritis: a nationwide study.
    Ma R; Zhang C; Liu J; Ren J; Huang H; Wang G; Ding Y; Li X · Frontiers in immunology · 2025
    Observational study19,394 participantsJoint Health forMagnesium
  53. Associations of Dietary Macroelements with Knee Joint Structures, Symptoms, Quality of Life, and Comorbid Conditions in People with Symptomatic Knee Osteoarthritis.
    Zhang Y; Chen T; Luo P; Li S; Zhu J; Xue S; Cao P; Zhu Z; Li J; Wang X; Wluka AE; Cicuttini F; Ruan G; Ding C · Nutrients · 2022
    Cohort study392 participantsJoint Health forMagnesium
  54. Predictive Model of Nail Consistency Using Scanning Electron Microscopy with Energy-Dispersive X-Ray.
    Mingorance Álvarez E; Martínez Quintana R; Pérez Pico AM; Mayordomo R · Biology · 2021
    Cross-sectional study57 participantsNail Health forCalcium
  55. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  56. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  57. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  58. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  59. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  60. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  61. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  62. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron