Product Image

Calcium Magnesium plus Boron

Solgar
4.8
★ ★ ★ ★ ★
(1130 ratings)
Boron 3 mg
Calcium 1000 mg
Magnesium 400 mg
Product Image
Score77
A strong-value calcium, magnesium, and boron formula with meaningful amounts. Mixed mineral forms and the high magnesium load are the main trade-offs.
How scoring works
Quantity:250 Tablet(s) • (83 servings)
Goals:
General Health
Bone Health
Testosterone Support
Stress Relief
Fitness
Heart Health
Energy
Cardiovascular Support

Score 77

A strong-value calcium, magnesium, and boron formula with meaningful amounts. Mixed mineral forms and the high magnesium load are the main trade-offs.
How scoring works
$15.83($0.19 per serving)
Pure Formulas
$ 16.79
Amazon
$ 47.49
Vitacost
$ 16.97
iHerb
$ 15.83
Daily Vita
$ 18.47
Report prices

Analysis

The three-tablet serving supplies 1,000 mg calcium, 400 mg magnesium, and 3 mg boron. Those amounts provide substantial bone and mineral support in a simple formula without unrelated ingredients.

Calcium and magnesium each combine better-absorbed citrate or gluconate forms with less favorable carbonate or oxide. This mixed approach balances cost and dose size but does not offer uniformly high form quality.

The product best fits adults with a clear need for both calcium and magnesium. Dividing the serving with meals may improve absorption and reduce gastrointestinal discomfort.

Who is it for
  • Adults needing substantial calcium and magnesium
  • People seeking a simple bone-mineral formula
  • Users comfortable taking three tablets
Best for
  • Bone-mineral supplementation
  • Combined calcium and magnesium intake
  • Adding boron to a mineral routine

Pros

  • Provides substantial calcium and magnesium
  • Includes 3 mg boron
  • Uses citrate and gluconate alongside basic forms
  • Focused ingredient list
  • Good ongoing value

Cons

  • Includes magnesium oxide and calcium carbonate
  • Requires three tablets
  • Does not include vitamin D or vitamin K
  • Large mineral serving may be hard to tolerate

Warnings

  • Calcium and magnesium can reduce absorption of levothyroxine, bisphosphonates, and tetracycline-class antibiotics when taken together, so doses need separation.
  • Four hundred milligrams of supplemental magnesium may cause loose stools or abdominal cramping.
  • People with kidney disease should not use high-dose calcium and magnesium without clinical supervision.

Nutrient quality

82 Highest impact

The mineral blend includes useful citrate and gluconate forms but also less absorbable carbonate and oxide. Calcium, magnesium, and boron are all supplied at meaningful amounts.

.

Ingredient transparency

68 High impact

Repeated full amounts across several forms make the elemental totals difficult to interpret. The supplied data does not include a complete inactive ingredient list.

.

Customer satisfaction

73 High impact

The aggregate satisfaction measure and review volume support a favorable first impression. Missing firsthand feedback leaves repeat complaints and real-world purpose fit uncertain.

.

Value for money

90 Highest impact

The low product cost is well matched to substantial amounts of three relevant minerals. Each serving provides strong value despite mixed absorption quality.

.
Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitA- Strength of SupportA- CoverageB+ Formula Quality
Magnesium · 400 mgBoron · 3 mg

The calcium, magnesium, and boron combination offers broad structural and metabolic support, especially for bones, muscles, and normal nerve function. The magnesium and boron amounts are meaningful, while the calcium-to-magnesium balance favors calcium.

The blend uses several mineral forms, including well-absorbed citrates alongside less absorbable oxide and carbonate. The formula is coherent for general health, though the substantial mineral load may be unnecessary for people who already obtain ample calcium from food.

Study evidence
Boron Supportive 6 studies
Magnesium Supportive 114 studies
Bone Health
Bone Health
Impact
Highest effect
A Goal FitB+ Strength of SupportB- CoverageB+ Formula Quality
Magnesium · 400 mgCalcium · 1000 mgBoron · 3 mg

Calcium and magnesium supply the main structural and regulatory minerals, while boron adds trace-mineral support. The amounts are substantial and directly relevant to bone maintenance.

Mixed citrate, gluconate, carbonate, and oxide sources provide some useful forms but also include less absorbable options. Vitamin D and vitamin K are missing, so calcium absorption and distribution depend more heavily on the rest of the diet.

Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Testosterone Support
Testosterone Support
Impact
High effect
B+ Goal FitC+ Strength of SupportB- CoverageB Formula Quality
Magnesium · 400 mgBoron · 3 mg

Magnesium provides a relevant route to testosterone support. The disclosed amount appears meaningful for that focused role.

Several complementary pathways broaden the formula. Calcium Magnesium plus Boron is best viewed as targeted support rather than proof of a clinical benefit.

Study evidence
Boron Disputed 3 studies
Magnesium Disputed 5 studies
Stress Relief
Stress Relief
Impact
High effect
B+ Goal FitB Strength of SupportC- CoverageC- Formula Quality
Magnesium · 400 mg

Magnesium provides the clearest stress-relief value through nervous-system and HPA-axis support, and the 400 mg amount is substantial. Calcium and boron are more relevant to mineral and structural health than to direct stress modulation.

Magnesium citrate and gluconate offer moderate absorption, but oxide lowers the blend quality. The high calcium-to-magnesium ratio may also compete with magnesium absorption, weakening the practical value of the otherwise strong label amount.

Study evidence
Magnesium Supportive 13 studies
Fitness
Fitness
Impact
High effect
C+ Goal FitB Strength of SupportC- CoverageB+ Formula Quality
Magnesium · 400 mg

Magnesium supports muscle function and recovery, while calcium and boron focus the formula on skeletal support. The magnesium amount is substantial but comes from a mix that includes oxide.

High calcium may compete with magnesium absorption and shifts the formula away from direct performance support. The three-tablet serving is better suited to bone and mineral maintenance than power, endurance, or post-workout repair.

Study evidence
Magnesium Disputed 29 studies
Heart Health
Heart Health
Impact
High effect
B Goal FitB Strength of SupportC- CoverageC Formula Quality
Magnesium · 400 mg

Magnesium offers meaningful support for heart rhythm and vascular tone. The disclosed amount is substantial, but a high calcium load makes the product less specifically heart-focused.

Citrate and gluconate improve the magnesium blend, while included oxide lowers absorption quality. Calcium and boron fit bone health more clearly and reduce cardiovascular focus.

Study evidence
Magnesium Supportive 158 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Carbonate, Calcium Citrate, Calcium Gluconate)
 1000 mg
Magnesium (Magnesium Citrate, Magnesium Gluconate, Magnesium Oxide)
 400 mg
Boron (Boron Citrate)
 3 mg
Gluten Free Adults 18–50 Kosher Dairy Free Sugar Free Vegetarian
Report overview
Calcium (Calcium Carbonate, Calcium Citrate, Calcium Gluconate) · 1000 mg OverallScore72
C+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA+ Value

The mixed calcium sources include citrate but also less absorbable carbonate and gluconate. Elemental calcium is clearly disclosed, though the 1,000 mg serving is larger than the body is likely to absorb efficiently at once. The low serving cost and added magnesium and boron support strong value.

View ingredientView products
Boron (Boron Citrate) · 3 mg OverallScore72
C Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyC Value

Boron citrate offers good absorption potential, and the serving provides a dose at the start of the preferred range. The amount is associated with the citrate form but is not explicitly labeled as elemental, while no trademark or purity certification is shown. Cost efficiency is fair for boron, though much of the formula is devoted to calcium and magnesium.

View ingredientView products
Magnesium (Magnesium Citrate, Magnesium Gluconate, Magnesium Oxide) · 400 mg OverallScore58
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value
+1

The magnesium blend combines better-absorbed forms with oxide, creating mixed absorption potential. The elemental amount is clearly disclosed and falls within the standard therapeutic range. A high calcium ratio may compete with absorption, despite the relatively low cost.

View ingredientView products
Loading alternative details
86 Performance

Calcium & Magnesium Citrate Powder with Vitamin D3

NOW
<p>Balanced calcium and magnesium citrate plus vitamin D3 offer stronger average form quality than the original mixed carbonate and oxide formula. Boron is missing, but the core bone-support minerals are clearly presented at meaningful amounts.</p>
80 Performance

Calcium Magnesium 1:1 Ratio

Bluebonnet
<p>Balanced calcium and magnesium use generally favorable citrate, malate, and aspartate forms. The formula omits boron and does not show how calcium is divided between forms, but the major-mineral profile is well aligned.</p>
81 Performance

Bone Restore

Life Extension
<p>Calcium, magnesium, vitamin D3, boron, zinc, and manganese provide broader bone-focused coverage while retaining the original boron role. Magnesium oxide and a calcium-heavy balance are the main quality trade-offs.</p>
85 Budget

Cal/Mag 500 mg/250 mg

NaturesPlus
<p>Chelated calcium and magnesium provide a balanced mineral blend with stronger form quality and excellent serving value. Boron is absent, so it best fits users whose priority is the two major minerals.</p>
78 Budget

Coral Calcium Plus

NOW
<p>Calcium and magnesium with vitamin D provide coherent bone support in an economical long-supply format. Citrate and aspartate improve part of the blend, while coral calcium, magnesium oxide, and no boron are trade-offs.</p>
80 Budget

Calcium Mag & D Complex

Nature's Way
<p>Citrate, malate, and aspartate forms improve a useful calcium-magnesium blend at a similar economical serving cost. Carbonate and oxide remain present, and the small vitamin D addition does not replace the original boron.</p>
85 Value

Cal/Mag Caps

NaturesPlus
<p>Amino acid chelates provide balanced calcium and magnesium with strong form quality and favorable serving value. The simple formula leaves out boron, but its core mineral delivery is more refined.</p>
82 Value

Calcium & Magnesium Mineral Complex

Nature's Way
<p>Magnesium bisglycinate and citrate plus calcium citrate and malate strengthen the mineral profile at practical serving value. Oxide and carbonate remain in the blend, and boron is not included.</p>
80 Value

Liquid Calcium Magnesium Citrate with Vitamin D3 Natural Strawberry Flavor

Solgar
<p>Calcium and magnesium citrate with vitamin D3 form a coherent liquid option with useful amounts and reasonable value. Duplicate vitamin D entries reduce label clarity, while the original boron support is absent.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Treatment with alendronate plus calcium, alendronate alone, or calcium alone for postmenopausal low bone mineral density.
    Bonnick S; Broy S; Kaiser F; Teutsch C; Rosenberg E; DeLucca P; Melton M · Current medical research and opinion · 2007
    Randomized trial701 participantsBone Health forCalcium
  2. Associations of dietary calcium intake with metabolic syndrome and bone mineral density among the Korean population: KNHANES 2008-2011.
    Kim MK; Chon SJ; Noe EB; Roh YH; Yun BH; Cho S; Choi YS; Lee BS; Seo SK · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Cross-sectional study14,705 participantsBone Health forCalcium
  3. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
    Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
    Meta-analysis1,566 participants7 studies pooledBone Health forCalcium
  4. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  5. Magnesium intake, bone mineral density, and fractures: results from the Women's Health Initiative Observational Study.
    Orchard TS; Larson JC; Alghothani N; Bout-Tabaku S; Cauley JA; Chen Z; LaCroix AZ; Wactawski-Wende J; Jackson RD · The American journal of clinical nutrition · 2014
    Cohort study73,684 participantsBone Health forMagnesium
  6. Dialysate Magnesium and Coronary Artery Calcification, Bone Mineral Density, and Cramping in Maintenance Hemodialysis: A Quasi-experimental Study.
    Srisuwarn P; Sethakarun S; Nongnuch A; Jongjirasiri S; Sritara C; Klyprayong P; Disthabanchong S · Kidney medicine · 2022
    Non-randomized trial40 participantsBone Health forMagnesium
  7. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  8. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  9. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  10. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  11. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  12. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  13. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  14. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  15. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  16. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  17. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  18. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  19. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  21. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  22. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  23. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  24. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  25. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  26. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  27. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy Fitness forMagnesium
  28. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  29. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  30. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  31. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  32. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  33. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forMagnesium
  34. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  35. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  36. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  37. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  38. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  39. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  40. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  41. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  42. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  43. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  44. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  45. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  46. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  47. Essentiality of boron for healthy bones and joints.
    Newnham RE · Environmental health perspectives · 1995
    Randomized trial20 participantsJoint Health forBoron
  48. Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study
    Zbigniew Pietrzkowski, Michael J Phelan, Robert Keller, Cynthia Shu, Ruby Argumedo, Tania Reyes-Izquierdo · Clinical Interventions in Aging · 2014
    Randomized trial60 participantsJoint Health forBoron
  49. A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis
    Romulus Scorei, Paul Mitrut, Iulian Petrisor, Iulia Scorei · Biological Trace Element Research · 2011
    Randomized trial60 participantsJoint Health forBoron
  50. Analgesic effect and safety of single-dose intra-articular magnesium after arthroscopic surgery: a systematic review and meta-analysis.
    Zeng C; Li YS; Wei J; Xie DX; Xie X; Li LJ; Gao SG; Luo W; Xiong YL; Xiao WF; Lei GH · Scientific reports · 2018
    Meta-analysis16 studies pooledJoint Health forMagnesium
  51. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
    Zeng C; Wei J; Terkeltaub R; Yang T; Choi HK; Wang YL; Xie DX; Hunter DJ; Zhang Y; Li H; Cui Y; Li LJ; Lei GH · Arthritis research & therapy · 2018
    Cross-sectional study13,947 participantsJoint Health forMagnesium
  52. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
    Shmagel A; Onizuka N; Langsetmo L; Vo T; Foley R; Ensrud K; Valen P · Osteoarthritis and cartilage · 2019
    Cohort study2,548 participantsJoint Health forMagnesium
  53. Associations of magnesium depletion score with the incidence and mortality of osteoarthritis: a nationwide study.
    Ma R; Zhang C; Liu J; Ren J; Huang H; Wang G; Ding Y; Li X · Frontiers in immunology · 2025
    Observational study19,394 participantsJoint Health forMagnesium
  54. Associations of Dietary Macroelements with Knee Joint Structures, Symptoms, Quality of Life, and Comorbid Conditions in People with Symptomatic Knee Osteoarthritis.
    Zhang Y; Chen T; Luo P; Li S; Zhu J; Xue S; Cao P; Zhu Z; Li J; Wang X; Wluka AE; Cicuttini F; Ruan G; Ding C · Nutrients · 2022
    Cohort study392 participantsJoint Health forMagnesium
  55. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  56. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  57. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  58. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  59. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  60. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  61. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  62. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  63. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  64. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  65. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  66. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  67. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium