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RegenerLife Watermelon

Natural Factors
4.8
★ ★ ★ ★ ★
(484 ratings)
Acetyl L-Carnitine 1500 mg
Glutathione 100 mg
Coenzyme Q-10 300 mg
Product Image
Score81
A strong non-stimulant combination of acetyl-L-carnitine and CoQ10 with supporting antioxidants. CoQ10 form and some secondary ingredient details remain unclear.
How scoring works
Quantity:2 Ounce(s) • (30 servings)
Goals:
Anti-Aging
Heart Health
Brain Health
Cognitive Support
Metabolism Boost
Mental Focus
Productivity Boost
Energy

Score 81

A strong non-stimulant combination of acetyl-L-carnitine and CoQ10 with supporting antioxidants. CoQ10 form and some secondary ingredient details remain unclear.
How scoring works
$41.97($1.39 per serving)
iHerb
$ 41.97
Amazon
$ 41.97
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Analysis

Acetyl-L-carnitine reaches 1.5 g and CoQ10 300 mg, giving the formula a meaningful non-stimulant foundation. Glutathione, melon-derived superoxide dismutase, and ElevATP add antioxidant and energy-related support.

The CoQ10 form is not identified, so absorption characteristics cannot be compared with clearly labeled ubiquinol or formulated ubiquinone. ElevATP is named by brand but its component breakdown is not supplied here, while 100 mg oral glutathione is a modest addition.

The powder fits users seeking cellular-energy support without caffeine. Its main ingredients are substantial, but a simpler, fully specified CoQ10 and carnitine formula could offer clearer value.

Who is it for
  • Adults seeking non-stimulant energy support
  • People wanting substantial acetyl-L-carnitine and CoQ10 together
  • Users comfortable with a premium multi-ingredient powder
Best for
  • Cellular-energy support without caffeine
  • Acetyl-L-carnitine and CoQ10 intake
  • Antioxidant-focused supplementation

Pros

  • Provides 1.5 g acetyl-L-carnitine
  • Includes 300 mg CoQ10
  • Avoids caffeine and stimulant overlap
  • Adds glutathione and superoxide dismutase

Cons

  • CoQ10 form is not identified
  • ElevATP composition is not shown in the supplied data
  • Oral glutathione amount is modest
  • Premium cost for partly opaque secondary ingredients

Warnings

  • CoQ10 may reduce the effect of warfarin, so users of vitamin K antagonist medicines should seek professional guidance
  • CoQ10 and acetyl-L-carnitine may lower blood pressure or cause digestive upset in some users
  • Acetyl-L-carnitine may be unsuitable without guidance for people with seizure disorders

Nutrient quality

89 Highest impact

Acetyl-L-carnitine, coenzyme Q, branded glutathione, and antioxidant enzymes create strong cellular-energy coverage. The glutathione amount is modest relative to the stronger cellular-energy ingredients.

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Ingredient transparency

89 Highest impact

Individual active weights are clearly disclosed. Some extract percentages, enzyme activity, or non-active label details remain incomplete.

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Customer satisfaction

70 High impact

The supplied rating is favorable and the feedback base is adequate. No complaint-level evidence was supplied to assess recurring issues or purpose-specific experiences.

.

Value for money

70 High impact

The serving cost is high relative to the certainty provided by the label. Substantial ingredients help, but disclosure gaps weaken category competitiveness.

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Goals

Anti-Aging
Impact
Highest effect
A- Goal FitA Strength of SupportA CoverageA Formula Quality
Coenzyme Q-10 · 300 mg

Acetyl-L-carnitine and CoQ10 provide strong mitochondrial and cellular-energy support, while glutathione and superoxide dismutase add antioxidant defenses. The combination directly addresses several mechanisms associated with declining energy and oxidative resilience.

The main mitochondrial actives are supplied at substantial amounts, though the ElevATP blend and oral enzyme contribution are less certain. CoQ10 may reduce warfarin effect, so users receiving vitamin K antagonist therapy may need closer anticoagulation monitoring.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Coenzyme Q-10 Supportive 6 studies
Heart Health
Impact
Highest effect
A Goal FitA Strength of SupportB+ CoverageA Formula Quality
Coenzyme Q-10 · 300 mg

The formula provides strong mitochondrial energy support with clear relevance to heart muscle. It provides 1,500 mg of acetyl-L-carnitine, 300 mg of CoQ10, and measured antioxidant compounds for the stated purpose.

The CoQ10 molecular form is not identified and lipid-management coverage is absent. CoQ10 may reduce warfarin’s anticoagulant effect and should be monitored when used together.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Brain Health
Impact
Highest effect
A- Goal FitA- Strength of SupportA CoverageA- Formula Quality

Acetyl-L-carnitine directly supports brain energy and acetylcholine production at a strong amount. CoQ10 and antioxidant ingredients add mitochondrial and oxidative-stress coverage.

The main actives are clearly disclosed and provide substantial multi-pathway support. The ElevATP blend is named only by total weight, which limits ingredient-level assessment.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Cognitive Support
Impact
Highest effect
B+ Goal FitA Strength of SupportB+ CoverageA Formula Quality
Acetyl L-Carnitine · 1500 mg

Acetyl-L-carnitine directly supports brain-cell energy and provides a plausible route to better mental stamina. The amount reaches the upper end of commonly studied use, while CoQ10 and antioxidant ingredients add complementary mitochondrial support.

The hydrochloride form and exact active amount are clear, though no branded source or purity testing is stated. The proprietary ElevATP blend is secondary and does not hide the main cognitive active.

Study evidence
Acetyl L-Carnitine Supportive 20 studies
Metabolism Boost
Impact
Highest effect
A- Goal FitA Strength of SupportB CoverageB+ Formula Quality
Coenzyme Q-10 · 300 mgAcetyl L-Carnitine · 1500 mg

Acetyl-L-carnitine and CoQ10 provide substantial support for fatty-acid transport and mitochondrial energy production. Their amounts create strong depth, while glutathione and superoxide dismutase add oxidative protection.

The formula stays centered on cellular energy despite including several supporting actives. The CoQ10 molecular form is not identified, and the proprietary ElevATP mixture prevents a full assessment of its contribution.

Study evidence
Acetyl L-Carnitine Adverse 1 study
Coenzyme Q-10 Disputed 11 studies
Mental Focus
Impact
Highest effect
B Goal FitA Strength of SupportB CoverageB+ Formula Quality
Acetyl L-Carnitine · 1500 mg

Acetyl-L-carnitine directly supports brain energy metabolism and acetylcholine production. Human evidence is more consistent for fatigue or age-related cognitive challenges than for acute focus in healthy adults.

The 1500 mg amount reaches the upper end of a standard clinical range and is paired with substantial CoQ10. Additional antioxidant and energy ingredients broaden support, though some are less directly tied to attention.

Study evidence
Acetyl L-Carnitine Supportive 7 studies

Ingredients

IngredientAmount per serving
Acetyl-L-Carnitine (Acetyl-L-Carnitine HCl)
1500 mg
Coenzyme Q10
300 mg
ElevATP
150 mg
Opitac (L-Glutathione)
100 mg
SOD B Extramel
10 mg
Superoxide Dismutase (Cucumis melo)
140 IU
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The formula supplies acetyl-L-carnitine hydrochloride at the top of the standard clinical range. Its exact amount is clear, though no branded carnitine source or purity-testing detail is supplied. Well-dosed CoQ10 and additional antioxidant ingredients help justify a serving cost that remains moderate for the active amount.

C- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value

Branded Opitac supports ingredient purity, but the standard powder format offers only basic absorption and digestive protection. The clearly listed 100 mg dose is practical to take yet modest for a standard oral form. Value is weak because the serving cost is high relative to the amount and delivery method.

Coenzyme Q-10 · 300 mg OverallScore53
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

A substantial CoQ10 amount comes with acetyl-L-carnitine, glutathione, and other complementary compounds. The powder does not identify the CoQ10 form or provide a lipid-based absorption aid. The broad formula has useful extras, but it is an expensive way to obtain CoQ10.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  2. Carnitine for fatigue in multiple sclerosis.
    Tejani AM; Wasdell M; Spiwak R; Rowell G; Nathwani S · The Cochrane database of systematic reviews · 2012
    Systematic review1 studies pooledEnergy forAcetyl L-Carnitine
  3. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  4. Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients.
    Rossini M; Di Munno O; Valentini G; Bianchi G; Biasi G; Cacace E; Malesci D; La Montagna G; Viapiana O; Adami S · Clinical and experimental rheumatology · 2007
    Randomized trial102 participantsEnergy forAcetyl L-Carnitine
  5. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  6. Acylcarnitines metabolism in depression: association with diagnostic status, depression severity and symptom profile in the NESDA cohort.
    Montanari S; Jansen R; Schranner D; Kastenmüller G; Arnold M; Janiri D; Sani G; Bhattacharyya S; Mahmoudian Dehkordi S; Dunlop BW; Rush AJ; Penninx BWHJ; Kaddurah-Daouk R; Milaneschi Y · Translational psychiatry · 2025
    Cohort study2,574 participantsEnergy forAcetyl L-Carnitine
  7. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsEnergy forAcetyl L-Carnitine
  8. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  9. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  10. The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
    Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  11. Can coenzyme q10 improve clinical and molecular parameters in fibromyalgia?
    Cordero MD; Alcocer-Gómez E; de Miguel M; Culic O; Carrión AM; Alvarez-Suarez JM; Bullón P; Battino M; Fernández-Rodríguez A; Sánchez-Alcazar JA · Antioxidants & redox signaling · 2014
    Randomized trial20 participantsEnergy forCoenzyme Q-10
  12. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
    Randomized trial67 participantsEnergy forAcetyl L-Carnitine
  13. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  14. A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
    Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
    Randomized trial239 participantsEnergy forAcetyl L-Carnitine
  15. Coenzyme Q10 supplementation in rheumatic diseases: A systematic review.
    Freire de Carvalho J; Skare T · Clinical nutrition ESPEN · 2024
    Systematic review483 participants20 studies pooledEnergy forCoenzyme Q-10
  16. Evaluating the effects of amantadin, modafinil and acetyl-L-carnitine on fatigue in multiple sclerosis--result of a pilot randomized, blind study.
    Ledinek AH; Sajko MC; Rot U · Clinical neurology and neurosurgery · 2014
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  17. Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome.
    Fukuda S; Nojima J; Kajimoto O; Yamaguti K; Nakatomi Y; Kuratsune H; Watanabe Y · BioFactors (Oxford, England) · 2017
    Randomized trial63 participantsEnergy forCoenzyme Q-10
  18. Carnitine for fatigue in multiple sclerosis.
    Tejani AM; Wasdell M; Spiwak R; Rowell G; Nathwani S · The Cochrane database of systematic reviews · 2010
    Systematic review1 studies pooledEnergy forAcetyl L-Carnitine
  19. Ubiquinol-10 Intake Is Effective in Relieving Mild Fatigue in Healthy Individuals.
    Mizuno K; Sasaki AT; Watanabe K; Watanabe Y · Nutrients · 2021
    Clinical trial62 participantsEnergy forCoenzyme Q-10
  20. Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
    Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
    Systematic reviewEnergy forAcetyl L-Carnitine
  21. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsAnti-Aging forAcetyl L-Carnitine
  22. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  23. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  24. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  25. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  26. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  27. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  28. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  29. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  30. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  31. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  32. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  33. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione
  34. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  35. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  36. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  37. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  38. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  39. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  40. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  41. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  42. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  43. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  44. A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
    Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
    Randomized trial63 participantsCognitive Support forAcetyl L-Carnitine
  45. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
    Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
    Randomized trial96 participantsCognitive Support forAcetyl L-Carnitine
  46. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  47. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  48. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  49. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  50. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  51. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  52. Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
    Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
    Randomized trial62 participantsMental Focus Productivity Boost forAcetyl L-Carnitine
  53. [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
    Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
    Non-randomized trial17 participantsMental Focus forAcetyl L-Carnitine
  54. Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
    Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
    Randomized trial112 participantsMental Focus forAcetyl L-Carnitine
  55. Acetyl-L-carnitine for patients with hepatic encephalopathy.
    Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
    Meta-analysis398 participants5 studies pooledMental Focus forAcetyl L-Carnitine
  56. Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
    Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
    Randomized trialMetabolism Boost forAcetyl L-Carnitine
  57. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  58. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  59. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  60. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
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