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Sleep + Wild Blueberry

Thorne Research
4.4
★ ★ ★ ★ ★
(62 ratings)
Theanine 200 mg
Melatonin 1 mg
Product Image
Score70
A gentle, transparent theanine-chamomile formula uses restrained melatonin, but the short supply makes it poor for routine value.
How scoring works
Quantity:15 Nutrient Disc(s) • (15 servings)
Goals:
Stress Relief
Sleep Support
Brain Health
Cognitive Support

Score 70

A gentle, transparent theanine-chamomile formula uses restrained melatonin, but the short supply makes it poor for routine value.
How scoring works
$33.00($2.20 per serving)
Pure Formulas
$ 33.00
iHerb
$ 0.00
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Analysis

The nutrient disc combines substantial theanine with chamomile extract and a low melatonin amount. The three ingredients cover relaxation and sleep onset without an aggressive melatonin dose.

Every active is disclosed, and chamomile is meaningfully larger than the token herbal additions seen in many sleep products. The unusual disc format and very short supply make routine use less economical.

The product fits adults who want a gentle, transparent bedtime formula and value an alternative delivery format. It is less suitable for long-term daily use when cost and refill frequency matter.

Who is it for
  • Adults seeking low-dose melatonin
  • People wanting a non-pill sleep format
Best for
  • Bedtime relaxation
  • Gentle sleep-onset support

Pros

  • Low melatonin amount
  • Substantial theanine serving
  • Fully disclosed chamomile extract

Cons

  • Very short supply
  • High serving cost
  • Disc format offers limited dose flexibility

Warnings

  • Melatonin may cause next-day drowsiness in sensitive users
  • Chamomile may trigger reactions in people sensitive to ragweed-family plants

Nutrient quality

93 Highest impact

The melatonin and theanine amounts are well balanced, with chamomile adding coherent support. Rapid dissolving delivery favors bedtime convenience but not sustained sleep maintenance.

Ingredient transparency

82 Highest impact

Every listed active amount is disclosed, and no proprietary blend obscures the formula. Complete daily directions and inactive-ingredient details are not available.

Customer satisfaction

56 Moderate impact

The aggregate satisfaction measure is favorable, with response volume determining how much confidence it deserves. Comment-level evidence is absent, so recurring complaints and purpose fit cannot be verified.

Value for money

37 Lower impact

Strong formula quality cannot offset the very high serving cost and short supply. The concise design avoids padding but remains poorly competitive on value.

Report analysis

Goals

Stress Relief
Stress Relief
Impact
Highest effect
A+ Goal FitA Strength of SupportA CoverageA+ Formula Quality
Theanine · 200 mg

L-theanine, chamomile, and low-dose melatonin form a targeted nighttime relaxation and sleep blend. L-theanine reaches a meaningful amount and has useful human evidence for relaxation.

The formula supports stress relief mainly through evening calm and sleep rather than daytime cortisol regulation. Melatonin can cause next-day drowsiness in some users and is better matched to nighttime use.

Study evidence
Melatonin Supportive 21 studies
Theanine Supportive 16 studies
Sleep Support
Sleep Support
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageA+ Formula Quality
Melatonin · 1 mgTheanine · 200 mg

Melatonin and L-theanine provide complementary support for circadian timing and mental relaxation. Both are supplied at well-aligned amounts, while chamomile adds modest botanical support.

The dissolving disc favors convenient bedtime use and likely rapid release, but it does not support sleep maintenance through sustained delivery. The formula is concise and avoids spreading its main actives too thin.

Study evidence
Melatonin Supportive 181 studies
Theanine Supportive 8 studies
Brain Health
Brain Health
Impact
High effect
C+ Goal FitB- Strength of SupportC- CoverageB+ Formula Quality

L-theanine may support calm attention, while melatonin and chamomile mainly support sleep. Better sleep can help next-day function, but the formula is not a broad cognitive supplement.

The L-theanine amount is well aligned and fully disclosed, while ingredient sourcing and purity are not documented. Melatonin can cause next-day drowsiness in some users, especially when the dissolving disc is taken too late.

Study evidence
Melatonin Supportive 29 studies
Theanine Supportive 17 studies
Cognitive Support
Cognitive Support
Impact
High effect
C- Goal FitB Strength of SupportD+ CoverageB Formula Quality
Theanine · 200 mg

L-theanine provides a meaningful calm-focus amount, while melatonin and the sleep-oriented format may indirectly support next-day cognition through rest. The main active amounts are clearly disclosed.

The formula is intended for nighttime use and does not directly target memory or processing speed. Melatonin can cause next-day drowsiness, so it is unsuitable before driving or other tasks that require alertness.

Study evidence
Theanine Supportive 25 studies
Mood Support
Mood Support
Impact
Moderate effect
D+ Goal FitB Strength of SupportD CoverageB Formula Quality

L-theanine may promote calm, while melatonin supports sleep timing rather than mood regulation itself. The product may help indirectly when poor sleep worsens irritability, but it lacks a direct daytime mood active.

The principal amounts are clear and practical for bedtime use. Melatonin may cause next-day drowsiness, and its combination with theanine can further reduce alertness in sensitive users.

Study evidence
Theanine Supportive 12 studies
Mental Focus
Mental Focus
Impact
Moderate effect
C+ Goal FitB+ Strength of SupportF CoverageF Formula Quality
Theanine · 200 mg

L-theanine reaches a useful amount for calm attention and has a plausible evidence base. Chamomile and melatonin shift the formula toward sleep rather than daytime mental performance.

The ingredients may suit evening relaxation but do not supply alertness or a complementary cognitive precursor. Melatonin can cause drowsiness and impaired daytime alertness, so the formula is poorly matched to tasks that require immediate focus.

Study evidence
Theanine Supportive 19 studies
Productivity Boost
Productivity Boost
Impact
Moderate effect
D- Goal FitC+ Strength of SupportD+ CoverageC+ Formula Quality
Theanine · 200 mg

Theanine offers only a limited connection to focused productivity. The principal relevant amounts appear substantial enough to contribute in practice.

Coverage is concentrated on calm focus and stress resilience. The broader formula is designed for another purpose, so several ingredients add little direct focus support.

Study evidence
Theanine Supportive 5 studies

Ingredients

IngredientAmount per serving
L-Theanine
200 mg
Chamomile Flowering top Extract
100 mg
Melatonin
1 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Women
Report overview
Theanine · 200 mg OverallScore76
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Explicit L-theanine identity confirms the active isomer, but no branded source or purity testing is shown. The clearly disclosed amount falls within the optimal range for calm and focused support. The effective amount is simple and clear, but the serving cost is high for generic L-theanine.

View ingredientView products
Melatonin · 1 mg OverallScore66
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

The 1 mg amount sits within the range most aligned with natural circadian signaling. The dissolving disc favors rapid onset, but it does not provide sustained release. The very high serving cost mainly pays for the dissolving disc, theanine, and chamomile rather than melatonin alone.

View ingredientView products
Loading alternative details
92 Performance

Tranquil Sleep

Natural Factors Stress-Relax
<p>Branded 200 mg Suntheanine, 3 mg melatonin, and 30 mg fully disclosed 5-HTP provide broad relaxation and sleep-onset support without an opaque blend. The 5-HTP can interact with serotonin-raising medicines, so that added depth is not appropriate for everyone.</p>
89 Performance

L-Theanine 200 mg Double Strength

Swanson
<p>A substantial 200 mg branded Suntheanine dose provides stronger, clearly identified relaxation support without melatonin. It may suit users who want to avoid next-day effects from melatonin, but it offers less direct support for sleep timing than the original.</p>
90 Performance

Melatonin 1.0 mg Orange Flavor

Source Naturals Sleep Science
<p>The focused 1 mg melatonin lozenge uses a conservative amount and avoids lightly dosed or undisclosed extras. It gives up the original formula’s theanine support, making it more suitable for sleep timing than broader bedtime relaxation.</p>
86 Budget

Fast-Dissolve Melatonin 3 mg Artificial Strawberry Flavor

Spring Valley
<p>The very low serving cost retains a clearly disclosed 3 mg melatonin dose in a fast-dissolve format. It omits L-theanine and the original formula’s other calming ingredients, so the savings come with narrower support.</p>
88 Budget

Melatonin 1 mg Fast Dissolve Strawberry Natural Flavor

Natrol
<p>The low-cost fast-dissolve tablet uses a conservative 1 mg melatonin amount for sleep timing. It is simpler than the original and leaves out L-theanine, making it a better fit when minimizing both cost and ingredient count matters.</p>
87 Budget

Melatonin Lozenges 3 mg

Life Extension
<p>A low serving cost provides 3 mg melatonin in a focused lozenge with no hidden blend. The streamlined formula is easier to assess than the original, though it does not provide L-theanine for relaxation support.</p>
94 Value

Sleep Regimen 3-in-1

NOW
<p>A low serving cost combines 3 mg melatonin, 200 mg L-theanine, and 50 mg Griffonia-derived 5-HTP with all amounts disclosed. The formula provides more bedtime depth for the money, but 5-HTP can interact with serotonin-raising medicines.</p>
89 Value

L-Theanine 100 mg

California Gold Nutrition
<p>Branded AlphaWave L-theanine supplies a clear 100 mg amount at a low serving cost. It offers clean relaxation support without melatonin, though users seeking direct sleep-timing support would need a different approach.</p>
88 Value

Melatonin Lozenge 2.5 mg

Nature's Way
<p>A practical 2.5 mg melatonin lozenge provides straightforward sleep-onset support at a very low serving cost. It lacks L-theanine and other calming actives, but the focused label offers clearer value than paying for lightly dosed extras.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  4. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  5. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  6. Current Evidence on Common Dietary Supplements for Sleep Quality.
    Esquivel MK; Ghosn B · American journal of lifestyle medicine · 2025
    Narrative reviewSleep Support forTheanine
  7. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  8. No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial.
    Kücükakin B; Wilhelmsen M; Lykkesfeldt J; Reiter RJ; Rosenberg J; Gögenur I · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2010
    Randomized trial50 participantsStress Relief forMelatonin
  9. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial.
    White DJ; de Klerk S; Woods W; Gondalia S; Noonan C; Scholey AB · Nutrients · 2016
    Randomized trial34 participantsStress Relief forTheanine
  10. Safety and Efficacy of AlphaWave® L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Moulin M; Crowley DC; Xiong L; Guthrie N; Lewis ED · Neurology and therapy · 2024
    Randomized trial30 participantsStress Relief Mental Focus Productivity Boost forTheanine
  11. Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Payne ER; Aceves-Martins M; Dubost J; Greyling A; de Roos B · Nutrition reviews · 2025
    Meta-analysis50 studies pooledMental Focus Brain Health Cognitive Support forTheanine
  12. Promising, but Not Completely Conclusive-The Effect of l-Theanine on Cognitive Performance Based on the Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Mátyus RO; Szikora Z; Bodó D; Vargáné Szabó B; Csupor É; Csupor D; Tóth B · Journal of clinical medicine · 2025
    Meta-analysis148 participants5 studies pooledCognitive Support forTheanine
  13. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  14. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  15. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  16. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  17. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  18. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsBrain Health Cognitive Support Sleep Support forTheanine
  19. A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population.
    Evans M; McDonald AC; Xiong L; Crowley DC; Guthrie N · Neurology and therapy · 2021
    Randomized trialBrain Health Stress Relief forTheanine
  20. Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task.
    Foxe JJ; Morie KP; Laud PJ; Rowson MJ; de Bruin EA; Kelly SP · Neuropharmacology · 2012
    Randomized trial27 participantsBrain Health Cognitive Support forTheanine
  21. Effects of l-Theanine on Cognitive Function in Middle-Aged and Older Subjects: A Randomized Placebo-Controlled Study.
    Baba Y; Inagaki S; Nakagawa S; Kaneko T; Kobayashi M; Takihara T · Journal of medicinal food · 2021
    Randomized trialBrain Health Mental Focus Productivity Boost forTheanine
  22. Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study.
    Dassanayake TL; Wijesundara D; Kahathuduwa CN; Weerasinghe VS · Nutritional neuroscience · 2023
    Randomized trial32 participantsCognitive Support forTheanine
  23. Acute effects of theanine, caffeine and theanine-caffeine combination on attention.
    Kahathuduwa CN; Dassanayake TL; Amarakoon AMT; Weerasinghe VS · Nutritional neuroscience · 2018
    Clinical trial20 participantsCognitive Support Mental Focus forTheanine
  24. Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study.
    Karunaratne UW; Dassanayake TL · Nutritional neuroscience · 2025
    Randomized trial24 participantsMental Focus forTheanine
  25. l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial.
    Shamabadi A; Kafi F; Arab Bafrani M; Asadigandomani H; A Basti F; Akhondzadeh S · Journal of affective disorders · 2023
    Randomized trial60 participantsMood Support forTheanine
  26. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study.
    Ritsner MS; Miodownik C; Ratner Y; Shleifer T; Mar M; Pintov L; Lerner V · The Journal of clinical psychiatry · 2011
    Randomized trial60 participantsMood Support Stress Relief forTheanine
  27. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.
    Williams JL; Everett JM; D'Cunha NM; Sergi D; Georgousopoulou EN; Keegan RJ; McKune AJ; Mellor DD; Anstice N; Naumovski N · Plant foods for human nutrition (Dordrecht, Netherlands) · 2020
    Systematic review9 studies pooledMood Support forTheanine
  28. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsMood Support Stress Relief forTheanine
  29. Anti-stress effect of theanine on students during pharmacy practice: positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.
    Unno K; Tanida N; Ishii N; Yamamoto H; Iguchi K; Hoshino M; Takeda A; Ozawa H; Ohkubo T; Juneja LR; Yamada H · Pharmacology, biochemistry, and behavior · 2014
    Randomized trial20 participantsMood Support forTheanine
  30. Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials.
    Gerolymos C; Saddier E; Boyer L; Fond G · Molecular psychiatry · 2026
    Meta-analysis1,168 participants31 studies pooledProductivity Boost forTheanine
  31. Effects of L-theanine on cognition, mood and sleep: evidence from human trials.
    Cotter J; Kilpatrick HE · Frontiers in nutrition · 2026
    Narrative reviewProductivity Boost forTheanine
  32. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together.
    Rogers PJ; Smith JE; Heatherley SV; Pleydell-Pearce CW · Psychopharmacology · 2008
    Randomized trial48 participantsProductivity Boost forTheanine
  33. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  34. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  35. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  36. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  37. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  38. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine
  39. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  40. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  41. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  42. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin