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L-Methylfolate 10 mg

Metabolic Maintenance
4.6
★ ★ ★ ★ ★
(256 ratings)
Glycine 260 mg
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Score71
A very high L-methylfolate capsule requires a specific supervised need, while its minor glycine amount offers little added value.
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Quantity:90 Capsule(s) • (90 servings)
Goals:

Score 71

A very high L-methylfolate capsule requires a specific supervised need, while its minor glycine amount offers little added value.
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Also available as

1 option
265.00mg Glycine • 90 Capsule(s) servings Glycine 265 mg • 90 Capsule(s) • 90 servings $50.00 ($0.55 per serving)
$63.00($0.70 per serving)
iHerb
$ 63.00
iHerb
$ 63.00
Pure Formulas
$ 63.00
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Analysis

The capsule provides L-methylfolate equivalent to 16.7 mg DFE, a very high specialty amount. Its purpose is targeted active-folate supplementation rather than broad nutrition.

Only 260 mg glycine is included, leaving it far below a meaningful standalone amount. Buyers seeking glycine would pay for a high-dose folate they may not need.

Ninety servings suit an established regimen but increase the importance of confirming appropriateness before long-term use. B12 status and medication context should guide the decision.

Who is it for
  • Adults with a clinician-directed methylfolate regimen
  • Users who specifically need a very high active-folate dose
  • People not shopping for glycine
Best for
  • Specialty high-dose methylfolate
  • Established clinician-guided use
  • One-capsule regimens

Pros

  • Uses active L-methylfolate
  • Clearly states the high folate amount
  • Ninety servings
  • One capsule per serving

Cons

  • Only 260 mg glycine
  • Very high folate dose
  • Poor glycine-specific value
  • Requires medical context

Warnings

  • High-dose folate can mask the blood signs of vitamin B12 deficiency while neurologic injury progresses, so B12 status matters before prolonged use.
  • People with bipolar disorder should use this dose only under clinical supervision because mood activation can occur.
  • A prescriber should review use with antifolate medicines such as methotrexate.

Nutrient quality

71 High impact

Very high-dose methylfolate with glycine in capsules gives the formula reasonable ingredient quality. The disclosed amounts are meaningful and the ingredient selection stays focused.

Ingredient transparency

83 Highest impact

Important active details are incomplete or internally inconsistent. Serving guidance and the complete inactive-ingredient list are not fully supplied.

Customer satisfaction

64 Moderate impact

The aggregate rating is favorable but the review volume limits confidence. No review excerpts are supplied to assess repeated complaints or purpose-specific experiences.

Value for money

61 Moderate impact

Premium positioning or disclosure limits weaken the value case. The useful active content appears limited relative to the serving cost.

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Ingredients

IngredientAmount per serving
Folate
16.7 mg DFE
Glycine
260 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Glycine · 260 mg OverallScore39
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value

Glycine is clearly disclosed but functions mainly as a minor companion to methylfolate. Its amount is far below a stand-alone sleep-support dose, and no purity standard is identified. The resulting cost per gram offers poor value for glycine-focused use.

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85 Performance

Glycine Powder

Metabolic Maintenance
<p>Glycine Powder provides a stronger or more purposeful glycine profile than the original for focused glycine use. The single-ingredient powder is easy to assess and practical to scale toward a multi-gram intake. The disclosed serving is useful, though no premium purity grade or source certification is provided.</p>
84 Performance

Glycine 1000 mg

Life Extension
<p>Glycine 1000 mg provides a stronger or more purposeful glycine profile than the original for focused glycine use. A clearly measured gram-level serving gives the focused capsule useful support for glycine-related pathways. Several capsules may be needed for higher multi-gram use, while source grade and inactive ingredients are not supplied.</p>
78 Performance

Glycine

Pure Encapsulations
<p>Glycine provides a stronger or more purposeful glycine profile than the original for focused glycine use. The focused formula supplies a useful intermediate glycine amount with clear active disclosure. A multi-capsule serving, very limited review volume, and no stated source grade keep the value only moderate.</p>
83 Budget

Pharmaceutical Grade AjiPure Glycine 500 mg

Swanson Ultra
<p>A lower serving cost makes Pharmaceutical Grade AjiPure Glycine 500 mg a more economical choice than the original. A branded pharmaceutical-grade source gives the simple capsule unusually clear raw-material quality. The serving remains modest for multi-gram glycine use, and the inactive-ingredient list is not supplied.</p>
80 Budget

Glycine 500 mg

Solgar
<p>A lower serving cost makes Glycine 500 mg a more economical choice than the original. The simple capsule clearly discloses glycine but provides an entry-level amount that may require several capsules for multi-gram use. Practical pricing and extensive feedback help, while source grade and inactive ingredients remain unclear.</p>
80 Budget

Glycine 500 mg

Country Life
<p>A lower serving cost makes Glycine 500 mg a more economical choice than the original. The disclosed glycine amount is modest, while vitamin B6 adds a relevant cofactor without solving the low glycine dose. Accessible value and broad feedback are positives, but source grade and inactive ingredients remain unclear.</p>
82 Value

Advanced Magnesium Complex

AOR Advanced Orthomolecular Research Advanced
<p>Advanced Magnesium Complex offers a more useful balance of glycine relevance and recurring cost than the original. Several absorbable magnesium forms and a substantial glycine yield make this a well-designed foundational mineral formula. The label does not separate how much elemental magnesium comes from each form, and several carriers overlap in purpose.</p>
79 Value

Melatonin 2 mg

Metabolic Maintenance
<p>Melatonin 2 mg offers a more useful balance of glycine relevance and recurring cost than the original. A practical melatonin amount gives the simple capsule strong alignment with sleep timing and onset. Glycine is relevant but far below a focused standalone amount, and no release profile is supplied.</p>
83 Value

DGL Ultra

Nature's Way
<p>DGL Ultra offers a more useful balance of glycine relevance and recurring cost than the original. Standardized DGL in a simple capsule supports the product’s digestive purpose, while glycine is only a minor addition. Serving value is reasonable for the DGL formula but very weak for anyone primarily seeking glycine.</p>
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