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Advanced Magnesium Complex

AOR Advanced Orthomolecular Research Advanced
4.8
★ ★ ★ ★ ★
(721 ratings)
Magnesium 300 mg
Glycine 1440 mg
Aspartic Acid 150 mg
Product Image
Score82

A well-designed mixed-form magnesium capsule with glycine and vitamin C. Strong form quality is balanced by the digestive effects possible at a 300 mg magnesium serving.

How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
General Health
Detoxification
Stress Relief
Energy
Cardiovascular Support
Bone Health
Heart Health
Testosterone Support

Score 82

A well-designed mixed-form magnesium capsule with glycine and vitamin C. Strong form quality is balanced by the digestive effects possible at a 300 mg magnesium serving.

How scoring works
$21.96($0.24 per serving)
iHerb
$ 21.96
Vitacost
$ 24.17
Amazon
$ 0.00
Pure Formulas
$ 21.97
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Analysis

The capsule provides 300 mg magnesium through ascorbate, aspartate, glycinate, and malate forms. That mix offers several well-used organic forms rather than relying on magnesium oxide.

Magnesium ascorbate also contributes 300 mg vitamin C, while magnesium glycinate supplies 1,440 mg glycine. Aspartate and malate provide additional named components that fit energy-related metabolism.

The one-capsule serving suits users seeking broad magnesium support for general health, stress, energy, and muscle function. A substantial magnesium amount may still cause loose stools, so tolerance determines whether the full serving is practical.

Who is it for
  • Adults seeking mixed organic magnesium forms
  • People wanting magnesium with glycine
  • Users preferring one capsule per serving
Best for
  • General magnesium supplementation
  • Stress and muscle support
  • Energy-related magnesium coverage

Pros

  • Uses glycinate, malate, aspartate, and ascorbate forms
  • Provides 300 mg magnesium
  • Includes 1,440 mg glycine
  • Adds 300 mg vitamin C
  • One-capsule serving

Cons

  • Large magnesium servings may loosen stools
  • Multiple forms make each individual contribution less clear
  • Not designed for targeted glycine use alone

Warnings

  • A 300 mg supplemental magnesium amount may cause loose stools or abdominal cramping
  • People with impaired kidney function should seek medical guidance before high-dose magnesium use
  • Separate use may be needed from medicines whose absorption is reduced by magnesium
  • Stop or reduce the serving if persistent diarrhea occurs

Nutrient quality

88 Highest impact

Glycinate, malate, aspartate, and ascorbate support strong form quality without magnesium oxide. The elemental magnesium and glycine amounts are useful, though the many carriers add some redundancy.

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Ingredient transparency

79 High impact

Total elemental magnesium and carrier amounts are disclosed clearly enough to judge the serving. Individual elemental contributions, complete directions, and non-active ingredients remain unavailable.

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Customer satisfaction

72 High impact

The aggregate rating is strong and supported by a large feedback volume. Specific experience details are missing, so recurring problems and purpose fit remain uncertain.

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Value for money

88 Highest impact

Multiple absorbable forms and a meaningful amount provide strong quality for the cost. Serving value is strong for a multi-form magnesium formula.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageA- Formula Quality
Magnesium · 300 mgGlycine · 1440 mgVitamin C · 300 mg

Magnesium from glycinate, malate, aspartate, and ascorbate supports energy production, muscle function, and nervous-system balance. Vitamin C and the substantial glycine yield add antioxidant, collagen, and calming support.

The elemental magnesium amount is clearly disclosed and sits in a useful supplemental range. Several absorbable forms strengthen the formula, though the glycine amount is below the level commonly used for dedicated sleep support and supplemental magnesium may loosen stools in sensitive users.

Study evidence
Glycine Supportive 4 studies
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Detoxification
Detoxification
Impact
Highest effect
A- Goal FitA Strength of SupportA CoverageA+ Formula Quality
Magnesium · 300 mgVitamin C · 300 mgGlycine · 1440 mg

Glycine directly supports Phase II conjugation and glutathione synthesis, while magnesium helps power liver enzymes and antioxidant production. Vitamin C adds antioxidant support, creating a coherent multi-pathway formula without speculative cleanse ingredients.

The glycine and magnesium amounts are substantial and fully disclosed, with several absorbable magnesium forms. Glycine remains below many dedicated high-dose uses, but the blend still provides meaningful depth across conjugation, energy, and antioxidant pathways.

Study evidence
Glycine Supportive 5 studies
Magnesium Supportive 19 studies
Vitamin C Supportive 9 studies
Stress Relief
Stress Relief
Impact
Highest effect
B+ Goal FitA+ Strength of SupportB CoverageA Formula Quality
Magnesium · 300 mgGlycine · 1440 mgVitamin C · 300 mg

Magnesium glycinate, malate, aspartate, and ascorbate provide strong foundational nerve support. Glycine adds a related calming pathway, making the blend more relevant than a basic magnesium oxide product.

The 300 mg magnesium amount is useful and the forms are clearly identified. Glycine remains below common standalone calming doses but complements the mineral strategy.

Study evidence
Glycine Supportive 1 study
Magnesium Supportive 13 studies
Energy
Energy
Impact
Highest effect
B+ Goal FitA+ Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 300 mg

The 300 mg magnesium amount supports ATP-dependent metabolism and uses several absorbable forms, including glycinate and malate. Clear elemental labeling and the absence of magnesium oxide strengthen practical delivery.

Malate and aspartate keep the formula centered on metabolic mineral support rather than several distinct energy pathways. The multiple forms are somewhat overlapping, but each is disclosed and the formula avoids an opaque proprietary blend.

Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A- Goal FitA Strength of SupportC+ CoverageB Formula Quality
Magnesium · 300 mgVitamin C · 300 mg

Magnesium supports vascular relaxation, blood-pressure regulation, and normal cardiac rhythm. The formula uses several well-absorbed forms and supplies a meaningful elemental amount.

Glycinate and malate strengthen form quality, while magnesium ascorbate adds a related antioxidant component. Multiple magnesium carriers add some redundancy, but individual forms and elemental magnesium are clearly disclosed.

Study evidence
Magnesium Supportive 123 studies
Bone Health
Bone Health
Impact
High effect
B- Goal FitB+ Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 300 mgVitamin C · 300 mgGlycine · 1440 mg

Magnesium supports bone crystal formation and vitamin-D metabolism, while a large glycine amount contributes to the organic matrix. Several organic magnesium forms improve absorption potential and provide more skeletal relevance than oxide-only products.

The total magnesium amount is useful, but the supplied form entries do not clearly separate elemental contributions. The formula lacks calcium, vitamin D, and vitamin K, so it works better as a complementary mineral-and-matrix product than complete bone support.

Study evidence
Glycine Disputed 6 studies
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Vitamin C (Magnesium Ascorbate)
 300 mg
Magnesium (Magnesium Ascorbate, Magnesium Aspartate, Magnesium Glycinate, Magnesium Malate)
 300 mg
Glycine (Magnesium Glycinate)
 1440 mg
Aspartate (Magnesium Aspartate)
 150 mg
Malate (Magnesium Malate)
 150 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Magnesium (Magnesium Ascorbate, Magnesium Aspartate, Magnesium Glycinate, Magnesium Malate) · 300 mg OverallScore84
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
+3

The blend uses several absorbable forms, including glycinate and malate. The label clearly states elemental magnesium in a useful dose. Its low serving cost strengthens the fit, although no patented chelate is identified.

View ingredientView products
Glycine (Magnesium Glycinate) · 1440 mg OverallScore75
C- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA- Value

The capsule clearly discloses a substantial glycine yield from magnesium glycinate, although it does not reach the dose commonly used for sleep. Its chelated form is less practical for rapid high-dose adjustment than free glycine powder or capsules. The low cost per gram and added magnesium forms provide good practical value.

View ingredientView products
Loading alternative details
91 Performance

Krebs Magnesium Potassium Complex

Nature's Way
Magnesium lysinate and malate provide well-defined forms with a useful potassium contribution and stronger supplied quality measures. The formula is narrower than the original and does not provide a separate glycine amount.
88 Performance

Magnesium Bisglycinate Powder

NOW
A clearly labeled bisglycinate powder provides a well-absorbed form with an adjustable serving and less uncertainty about overlapping carriers. It trades the original's broader magnesium blend for a cleaner single-form approach.
85 Performance

Magnesium Bisglycinate Chelate

Healthy Origins
TRAACS magnesium bisglycinate offers a clearly identified chelated form and stronger magnesium-specific quality than the original. The focused formula lacks the original's malate, aspartate, vitamin C, and substantial glycine yield.
83 Budget

Magnesium Citrate Pure Powder

Best Naturals
The pure powder is much more economical per serving and clearly provides magnesium citrate without an overlapping blend of carriers. It omits the original's glycine and multiple magnesium forms, so it suits someone who wants a simpler magnesium option.
80 Budget

Magnesium Caps 500 mg

Life Extension
A very low serving cost and several magnesium forms make this a practical budget choice. Magnesium oxide lowers absorption quality, and the substantial amount may be harder on digestion than the original blend.
84 Budget

Potassium + Magnesium

Nutricost
The simple citrate-based formula costs less per serving and adds a modest potassium amount for broader mineral coverage. It does not provide the original's glycine or form diversity, but its focused design offers strong routine value.
85 Value

Magnesium Bisglycinate 200 mg

Natural Factors
The clearly identified bisglycinate form combines strong absorption potential with favorable supplied quality and value measures. It is less comprehensive than the original, but avoids uncertainty about how the magnesium amount is divided among forms.
83 Value

Magnesium Citrate 420 mg

Nutricost
A substantial citrate amount and low serving cost provide straightforward value for users who mainly want magnesium. Citrate may loosen stools, and the formula does not preserve the original's glycine or multi-form coverage.
81 Value

Ultra-Mag

Source Naturals
A broad blend of citrate, glycinate, malate, succinate, and taurate closely matches the original's multi-pathway approach while remaining economical. The label does not separate each form's share, and the substantial magnesium and vitamin B6 amounts may limit tolerability.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis.
    Leenders NHJ; Vermeulen EA; van Ballegooijen AJ; Hoekstra T; de Vries R; Beulens JW; Vervloet MG · Clinical nutrition (Edinburgh, Scotland) · 2021
    Meta-analysis348,059 participants33 studies pooledGeneral Health forMagnesium
  2. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  3. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  4. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsFitness Energy forMagnesium
  5. The effect of magnesium supplementation on muscle fitness: a meta-analysis and systematic review.
    Wang R; Chen C; Liu W; Zhou T; Xun P; He K; Chen P · Magnesium research · 2018
    Meta-analysis542 participants14 studies pooledFitness forMagnesium
  6. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  7. Effects of zinc and magnesium supplements on postpartum depression and anxiety: A randomized controlled clinical trial.
    Fard FE; Mirghafourvand M; Mohammad-Alizadeh Charandabi S; Farshbaf-Khalili A; Javadzadeh Y; Asgharian H · Women & health · 2017
    Randomized trial99 participantsStress Relief forMagnesium
  8. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  9. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  10. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes.
    Cruz M; Maldonado-Bernal C; Mondragón-Gonzalez R; Sanchez-Barrera R; Wacher NH; Carvajal-Sandoval G; Kumate J · Journal of endocrinological investigation · 2009
    Randomized trial74 participantsAnti-Inflammatory Support forGlycine
  11. Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial.
    Vargas MH; Del-Razo-Rodríguez R; López-García A; Lezana-Fernández JL; Chávez J; Furuya MEY; Marín-Santana JC · BMC pulmonary medicine · 2018
    Randomized trial13 participantsAnti-Inflammatory Support forGlycine
  12. Subgingival air polishing (glycine powder) versus minocycline hydrochloride: efficacy in residual periodontal pockets following endoscope-assisted scaling and root planing.
    Guo X; Bai H; Lu X; Guo J; Qi Y; Huo X; Li S · Clinical oral investigations · 2026
    Randomized trial80 participantsAnti-Inflammatory Support forGlycine
  13. Long-term Implant Maintenance: A Systematic Review of Home and Professional Care Strategies in Supportive Implant Therapy.
    Araújo TG; Moreira CS; Neme RA; Luan H; Bertolini M · Brazilian dental journal · 2024
    Systematic review13 studies pooledAnti-Inflammatory Support forGlycine
  14. Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.
    Pan T; Meng W; Zhang M; Xie Y; Chen Z; Zhou M; Yin L; Xie H · BMC oral health · 2026
    Randomized trial198 participantsAnti-Inflammatory Support forGlycine
  15. Dietary magnesium intake is inversely associated with serum C-reactive protein levels: meta-analysis and systematic review.
    Dibaba DT; Xun P; He K · European journal of clinical nutrition · 2014
    Meta-analysis32,918 participants7 studies pooledAnti-Inflammatory Support forMagnesium
  16. Efficacy and safety of magnesium glycinate as add on therapy in hypomagnesemic asthma and chronic obstructive pulmonary disease patients: A randomised controlled study assessing inflammatory biomarkers.
    Maddirevula MK; Rajanandh MG; Wesley B · Pulmonary pharmacology & therapeutics · 2026
    Randomized trial224 participantsAnti-Inflammatory Support forMagnesium
  17. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsAnti-Inflammatory Support forMagnesium
  18. The effect of long-term magnesium intake on inflammatory markers in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Wang W; Wang J; Yang Y; Shi Y · Frontiers in nutrition · 2025
    Meta-analysis444 participants8 studies pooledAnti-Inflammatory Support forMagnesium
  19. Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials.
    Veronese N; Pizzol D; Smith L; Dominguez LJ; Barbagallo M · Nutrients · 2022
    Meta-analysis889 participants17 studies pooledAnti-Inflammatory Support forMagnesium
  20. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  21. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  22. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  23. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  24. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  25. Implantoplasty Versus Glycine Air Abrasion for the Surgical Treatment of Peri-implantitis: A Randomized Clinical Trial.
    Lasserre JF; Brecx MC; Toma S · The International journal of oral & maxillofacial implants · 2020
    Randomized trial31 participantsBone Health forGlycine
  26. Amino Acid Intakes Are Associated With Bone Mineral Density and Prevalence of Low Bone Mass in Women: Evidence From Discordant Monozygotic Twins.
    Jennings A; MacGregor A; Spector T; Cassidy A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study135 participantsBone Health forGlycine
  27. Type V osteogenesis imperfecta: a new form of brittle bone disease.
    Glorieux FH; Rauch F; Plotkin H; Ward L; Travers R; Roughley P; Lalic L; Glorieux DF; Fassier F; Bishop NJ · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2001
    Other3 participantsBone Health forGlycine
  28. Associations of Dietary and Circulating Choline and Glycine With Bone Mineral Density: UK Biobank Analyses With Mendelian Randomization.
    Chen S; Lu R; Zhang Y; Li Y; Cao X; Yang H; Lin J · International journal of endocrinology · 2026
    Cross-sectional study18,769 participantsBone Health forGlycine
  29. Metabolomic insights into amino acid signatures and pathways associated with osteoporosis in Iranian elderly population.
    Dehghanbanadaki H; Soltani A; Majidi Z; Rezaei-Tavirani M; Shafiee G; Ostovar A; Bandarian F; Najjar N; Larijani B; Nabipour I; Khashayar P; Fahimfar N; Razi F · Frontiers in medicine · 2025
    Cross-sectional study1,916 participantsBone Health forGlycine
  30. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  31. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  32. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  33. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  34. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  35. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  36. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  37. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  38. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  39. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  40. The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway.
    Tan HC; Hsu JW; Tai ES; Chacko S; Kovalik JP; Jahoor F · Frontiers in endocrinology · 2024
    Cohort study42 participantsDetoxification forGlycine
  41. Metabolic impact of dietary glycine supplementation in individuals with severe obesity.
    Tan HC; Hsu JW; Tai ES; Chacko S; Wu V; Yen PM; Kovalik JP; Jahoor F · Scientific reports · 2025
    Single-arm trial19 participantsDetoxification forGlycine
  42. Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study.
    Irwin C; van Reenen M; Mason S; Mienie LJ; Westerhuis JA; Reinecke CJ · PloS one · 2017
    Non-randomized trial21 participantsDetoxification forGlycine
  43. Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function.
    Furuya KN; Durie PR; Roberts EA; Soldin SJ; Verjee Z; Yung-Jato L; Giesbrecht E; Ellis L · Clinical biochemistry · 1996
    Methods validation study74 participantsDetoxification forGlycine
  44. The treatment of isovaleric acidemia with glycine supplement
    M Naglak, R Salvo, K Madsen, P Dembure, L Elsas · Pediatric research · 1988
    Non-randomized trial2 participantsDetoxification forGlycine
  45. Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics.
    Gullestad L; Dolva LO; Søyland E; Manger AT; Falch D; Kjekshus J · Alcoholism, clinical and experimental research · 1992
    Randomized trial49 participantsDetoxification forMagnesium
  46. Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study.
    Farshidi H; Sobhani AR; Eslami M; Azarkish F; Eftekhar E; Keshavarz M; Soltani N · Journal of cardiovascular pharmacology · 2021
    Randomized trialDetoxification forMagnesium
  47. Effects of Synbiotic Food Consumption on Serum Minerals, Liver Enzymes, and Blood Pressure in Patients with Type 2 Diabetes: A Double-blind Randomized Cross-over Controlled Clinical Trial.
    Asemi Z; Aarabi MH; Hajijafari M; Alizadeh SA; Razzaghi R; Mazoochi M; Esmaillzadeh A · International journal of preventive medicine · 2020
    Randomized trialDetoxification forMagnesium
  48. Clinical experience with 781 cases of alcoholism evaluated and treated on an inpatient basis by various methods.
    Daus AT; Freeman WM; Wilson J; Aponte C · The International journal of the addictions · 1985
    Observational study781 participantsDetoxification forMagnesium
  49. Ionized hypomagnesemia in patients undergoing orthotopic liver transplantation: a complication of citrate intoxication.
    Scott VL; De Wolf AM; Kang Y; Altura BT; Virji MA; Cook DR; Altura BM · Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 1997
    Single-arm trialDetoxification forMagnesium
  50. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  51. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  52. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  53. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  54. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C
  55. Oral or nasogastric maintenance therapy for diarrhoea of unknown aetiology resembling cholera.
    Nalin DR; Cash RA · Transactions of the Royal Society of Tropical Medicine and Hygiene · 1971
    Clinical trialDigestive Health forGlycine
  56. Prevention and treatment of infectious diarrhea. Speculations on the next 10 years.
    Edelman R · The American journal of medicine · 1985
    Narrative reviewDigestive Health forGlycine
  57. Super ORS.
    Bhattacharya SK; Dutta P; Dutta D; Chakraborti MK · Indian journal of public health · 1991
    Narrative reviewDigestive Health forGlycine
  58. A comparative study of glycine fortified oral rehydration solution with standard WHO oral rehydration solution.
    Antony TJ; Mohan M · Indian pediatrics · 1990
    Randomized trial50 participantsDigestive Health forGlycine
  59. Rice-powder salt solution in the treatment of acute diarrhea in young children.
    Sabchareon A; Chongsuphajaisiddhi T; Kittikoon P; Chanthavanich P · The Southeast Asian journal of tropical medicine and public health · 1993
    Randomized trial64 participantsDigestive Health forGlycine
  60. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  61. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  62. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  63. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  64. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  65. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsFitness forMagnesium
  66. Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.
    Welch AA; Kelaiditi E; Jennings A; Steves CJ; Spector TD; MacGregor A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Cross-sectional study2,570 participantsFitness forMagnesium
  67. Nutritional intake as a determinant of high-speed resistance and multicomponent training efficacy on strength in older women at risk of sarcopenia. A randomized clinical trial.
    Polo-Ferrero L; Recio-Rodriguez JI; González-Manzano S; Martín-Vallejo J; Barbero-Iglesias FJ; Montero-Errasquín B; Cruz-Jentoft AJ; Méndez-Sánchez R · Clinical nutrition (Edinburgh, Scotland) · 2025
    Randomized trial80 participantsFitness forMagnesium
  68. Minerals and Sarcopenia in Older Adults: An Updated Systematic Review.
    van Dronkelaar C; Fultinga M; Hummel M; Kruizenga H; Weijs PJM; Tieland M · Journal of the American Medical Directors Association · 2023
    Systematic review45 studies pooledFitness forMagnesium
  69. Inter-individual variability in redox and performance responses after antioxidant supplementation: A randomized double blind crossover study.
    Margaritelis NV; Nastos GG; Vasileiadou O; Chatzinikolaou PN; Theodorou AA; Paschalis V; Vrabas IS; Kyparos A; Fatouros IG; Nikolaidis MG · Acta physiologica (Oxford, England) · 2023
    Randomized trial44 participantsFitness forVitamin C
  70. Antioxidant supplementation, redox deficiencies and exercise performance: A falsification design.
    Margaritelis NV; Paschalis V; Theodorou AA; Kyparos A; Nikolaidis MG · Free radical biology & medicine · 2021
    Randomized trial73 participantsFitness forVitamin C
  71. A significant relationship between plasma vitamin C concentration and physical performance among Japanese elderly women.
    Saito K; Yokoyama T; Yoshida H; Kim H; Shimada H; Yoshida Y; Iwasa H; Shimizu Y; Kondo Y; Handa S; Maruyama N; Ishigami A; Suzuki T · The journals of gerontology. Series A, Biological sciences and medical sciences · 2012
    Cross-sectional study655 participantsFitness forVitamin C
  72. Low vitamin C values are linked with decreased physical performance and increased oxidative stress: reversal by vitamin C supplementation.
    Paschalis V; Theodorou AA; Kyparos A; Dipla K; Zafeiridis A; Panayiotou G; Vrabas IS; Nikolaidis MG · European journal of nutrition · 2016
    Clinical trial20 participantsFitness forVitamin C
  73. Low dietary vitamin C intake is associated with low muscle strength among elderly Korean women.
    Park CY; Shin S · Nutrition research (New York, N.Y.) · 2024
    Cross-sectional study14,844 participantsFitness forVitamin C
  74. Air-abrasive debridement with glycine powder versus manual debridement and chlorhexidine administration for the maintenance of peri-implant health status: a six-month randomized clinical trial.
    Lupi SM; Granati M; Butera A; Collesano V; Rodriguez Y Baena R · International journal of dental hygiene · 2018
    Randomized trial46 participantsGeneral Health forGlycine
  75. The effects of glycine on auditory mismatch negativity in schizophrenia.
    Greenwood LM; Leung S; Michie PT; Green A; Nathan PJ; Fitzgerald P; Johnston P; Solowij N; Kulkarni J; Croft RJ · Schizophrenia research · 2018
    Randomized trial22 participantsGeneral Health forGlycine
  76. Dietary glycine improves urine storage symptoms in urology outpatients.
    Sugaya K; Oh-Oka H; Yamada T; Miyata M; Ashitomi K; Kadekawa K; Nishijima S · Journal of complementary & integrative medicine · 2021
    Non-randomized trial20 participantsGeneral Health forGlycine
  77. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure.
    Díaz-Flores M; Cruz M; Duran-Reyes G; Munguia-Miranda C; Loza-Rodríguez H; Pulido-Casas E; Torres-Ramírez N; Gaja-Rodriguez O; Kumate J; Baiza-Gutman LA; Hernández-Saavedra D · Canadian journal of physiology and pharmacology · 2014
    Randomized trial60 participantsGeneral Health Stress Relief forGlycine
  78. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  79. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  80. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  81. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  82. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  83. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  84. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  85. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  86. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  87. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  88. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  89. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  90. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  91. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  92. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  93. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  94. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  95. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  96. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  97. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  98. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  99. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium