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Glycine 1000 mg

Life Extension
4.8
(14616 ratings)
Glycine 1000 mg
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Score97

A clinical-strength, high-dose glycine capsule that supports detoxification and a calm nervous system.

How scoring works
Quantity:100 Capsule(s)(100 servings)
Goals:
Detoxification
Anti-Inflammatory Support

Score 97

A clinical-strength, high-dose glycine capsule that supports detoxification and a calm nervous system.

How scoring works
$12.00($0.12 per serving)
Pure Formulas
$ 12.00
iHerb
$ 12.00
Amazon
$ 16.43
Vitacost
$ 12.00
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Analysis

This product provides a significant dose of glycine, which is a fundamental substrate for your body's detoxification processes and glutathione production. The 1,000 mg serving is much higher than standard capsules, making it easier to support metabolic clearance without taking multiple pills.

Free-form delivery ensures that the amino acid is quickly absorbed and available for the nervous system and liver. I suggest this for patients who need robust support for systemic balance and antioxidant status.

Pros

  • Exceptional dose per capsule
  • Highly cost-effective
  • Supports glutathione synthesis
  • Pure free-form amino acid

Cons

  • Capsule size may be larger
  • May cause significant drowsiness
  • Limited to 100 servings

Warnings

  • Best taken before bedtime
  • Monitor for deep relaxation effects
  • Check with a doctor if on medications

Nutrient quality

96 Highest impact

The 1,000 mg dose is meaningfully concentrated to align with therapeutic goals for detoxification and sleep. Pure glycine in a free-form format ensures maximum bioavailability and physiological activity.

Ingredient transparency

99 Highest impact

Labeling is exceptionally clear, identifying the exact dosage of the active amino acid per serving. Naming conventions are precise and support accurate clinical comparison and evaluation.

Customer satisfaction

96 Highest impact

Consistently high ratings from a very large review pool reflect significant efficacy and consumer trust. Users frequently report positive outcomes for sleep quality, detoxification support, and overall calm.

Value for money

97 Highest impact

The cost per effective dose is excellent, providing high-potency support at an affordable price per serving. This product offers exceptional value for patients requiring long-term amino acid supplementation.

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Goals

Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality

Glycine provides a fundamental substrate for Phase II conjugation pathways, specifically the glycination of environmental toxins. This amino acid is essential for neutralizing waste products and supporting gut barrier integrity.

Supplemental levels may contribute to more efficient metabolic clearance by ensuring substrate availability. The free-form delivery ensures rapid uptake for cellular utilization.

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Impact
High effect
B Goal FitB+ Strength of SupportD- CoverageA Formula Quality

Glycine is an amino acid that provides direct immunomodulatory effects by acting on chloride channels in inflammatory cells. This 1000 mg dose helps reduce the production of pro-inflammatory cytokines and supports tissue repair.

The capsule format ensures easy intake and consistent dosing for systemic support. Glycine is also a precursor for glutathione, a major endogenous antioxidant involved in resolving inflammatory responses.

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Ingredients

IngredientAmount per serving
Glycine
1000 mg
Adults 18–50
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Glycine · 1000 mg OverallScore81
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA- Value
This high-dose glycine capsule offers 1,000 mg per serving, making it easier to reach clinical targets with fewer pills. It is a highly transparent and cost-effective option for daily supplementation.
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