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Nu Clarity

CogniTune Smarter Health
4.3
★ ★ ★ ★ ★
(285 ratings)
Huperzine 100 mcg
Rhodiola
Bacopa 300 mg
Ginkgo
Alpha-GPC 200 mg
Product Image
Score76
A broad, non-caffeine cognitive stack offers useful ingredient coverage and reasonable value. Missing standardization details and interaction concerns prevent it from being an easy default choice.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Brain Health
Cognitive Support
Mental Focus
Stress Relief
Mood Support
Productivity Boost
Energy

Score 76

A broad, non-caffeine cognitive stack offers useful ingredient coverage and reasonable value. Missing standardization details and interaction concerns prevent it from being an easy default choice.
How scoring works
$19.97($0.66 per serving)
Walmart
$ 19.97
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Analysis

The formula centers on 300 mg of bacopa, 200 mg of alpha-GPC, and 100 mg each of phosphatidylserine, ginkgo, rhodiola, and huperzine A at 100 mcg. It covers memory formation, cholinergic signaling, stress response, membranes, and circulation without relying on caffeine.

Bacosides, ginkgo markers, rosavins, and salidrosides are named but not given as percentages. The alpha-GPC concentration is also not clarified, so the amount of active alpha-GPC may be lower than the listed raw-material weight.

Two capsules and reasonable cost make the stack practical relative to other broad nootropics. Users still need to account for the long half-life of huperzine A and ginkgo-related medication interactions.

Who is it for
  • Adults seeking non-stimulant memory and focus support
  • Experienced nootropic users
  • People who want bacopa, alpha-GPC, and phosphatidylserine together
Best for
  • Broad cognitive pathway coverage
  • Caffeine-free focus routines
  • Combining bacopa with cholinergic ingredients

Pros

  • Provides a well-aligned bacopa amount
  • Includes alpha-GPC and phosphatidylserine
  • Adds rhodiola and ginkgo
  • Clearly states the huperzine A amount
  • Uses only two capsules

Cons

  • Active-marker percentages are missing
  • Alpha-GPC concentration is unclear
  • Acetyl-L-carnitine is modest
  • No cycling guidance is supplied for huperzine A
  • Medication fit requires careful review

Warnings

  • Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines.
  • Huperzine A may cause nausea, vivid dreams, slowed heart rate, or additive effects with cholinergic medicine.
  • Rhodiola may feel activating and can disrupt sleep when taken late in sensitive users.

Nutrient quality

83 Highest impact

Standardized bacopa, ginkgo, and rhodiola extracts accompany useful choline and phospholipid forms. Bacopa, alpha-GPC, and phosphatidylserine have practical amounts, while acetyl-L-carnitine is comparatively light.

Ingredient transparency

69 High impact

Specific quantities are listed for every active ingredient. Capsule materials and other inactive ingredients are not provided.

Customer satisfaction

61 Moderate impact

The supplied aggregate rating is solid but not exceptional, and no experience details are provided. No specific feedback is supplied, so recurring complaints cannot be assessed.

Value for money

89 Highest impact

The coherent and mostly well-dosed cognitive formula offers strong quality for its cost. The serving cost is reasonable for the number of meaningful actives provided.

Report analysis

Goals

Brain Health
Impact
Highest effect
A Goal FitB Strength of SupportA- CoverageA Formula Quality
Huperzine · 100 mcgBacopa · 300 mgAlpha-GPC · 200 mg

Bacopa, Alpha-GPC, phosphatidylserine, ginkgo, rhodiola, huperzine A, and acetyl-L-carnitine form a strongly targeted cognitive stack. The formula addresses memory formation, acetylcholine, neuronal membranes, circulation, stress resilience, and brain energy.

Alpha-GPC and acetyl-L-carnitine are moderate or low, and botanical marker percentages are not fully stated. Huperzine A may cause nausea, insomnia, or a slow heart rate and can interact with cholinergic or anticholinergic medicines.

Study evidence
Alpha-GPC Supportive 12 studies
Bacopa Supportive 17 studies
Ginkgo Supportive 90 studies
Huperzine Supportive 17 studies
Rhodiola Supportive 8 studies
Cognitive Support
Impact
Highest effect
A Goal FitC+ Strength of SupportA CoverageA Formula Quality
Huperzine · 100 mcgAlpha-GPC · 200 mgBacopa · 300 mg

Bacopa, Alpha-GPC, phosphatidylserine, ginkgo, rhodiola, huperzine A, and acetyl-L-carnitine create an unusually comprehensive nootropic stack. Bacopa and huperzine A reach useful amounts, while several other actives are moderate and extract standardization is incomplete.

The formula covers memory formation, cholinergic signaling, cell membranes, circulation, stress resilience, and cognitive energy. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines, while huperzine A can cause cholinergic effects and interact with cholinergic or anticholinergic drugs.

Study evidence
Alpha-GPC Supportive 15 studies
Bacopa Supportive 30 studies
Ginkgo Supportive 87 studies
Huperzine Supportive 22 studies
Rhodiola Supportive 7 studies
Mental Focus
Impact
High effect
A- Goal FitC+ Strength of SupportB+ CoverageB Formula Quality
Alpha-GPC · 200 mgHuperzine · 100 mcg

Bacopa, Alpha-GPC, phosphatidylserine, ginkgo, Rhodiola, acetyl-L-carnitine, and huperzine A form a genuinely cognitive-focused stack. The combination spans memory, acetylcholine, stress resilience, and circulation rather than relying on a single stimulant.

Several ingredients are supporting rather than full standalone doses, and marker percentages are missing for key botanicals. Huperzine A can add cholinergic effects, while ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines.

Study evidence
Alpha-GPC Supportive 1 study
Bacopa Supportive 13 studies
Ginkgo Supportive 28 studies
Huperzine Not classified

No linked studies yet.

Rhodiola Supportive 15 studies
Stress Relief
Impact
High effect
B Goal FitB- Strength of SupportB CoverageB+ Formula Quality

Bacopa and rhodiola provide adaptogenic support, while phosphatidylserine and other cognitive ingredients may help mental performance under stress. Bacopa reaches a commonly used extract weight, and rhodiola names its key marker families.

Active percentages are not disclosed, and rhodiola is below a stronger standalone amount. Ginkgo may raise bleeding risk with anticoagulant or antiplatelet medicines, while huperzine A can interact with cholinergic or anticholinergic drugs.

Study evidence
Bacopa Supportive 8 studies
Rhodiola Supportive 16 studies
Mood Support
Impact
High effect
B Goal FitC+ Strength of SupportB+ CoverageB Formula Quality

Bacopa, rhodiola, phosphatidylserine, and acetyl-L-carnitine provide plausible stress and brain-support pathways. The formula is aimed more at cognition than mood, and several extracts lack active-marker percentages.

Bacopa reaches a commonly studied extract amount, while rhodiola is better suited as a supporting dose. Ginkgo may increase bleeding risk with anticoagulant or antiplatelet medicines, and huperzine A may add cholinergic effects such as nausea or slowed heart rate.

Study evidence
Alpha-GPC Supportive 1 study
Bacopa Supportive 7 studies
Rhodiola Supportive 15 studies
Productivity Boost
Impact
High effect
A- Goal FitC Strength of SupportB+ CoverageC Formula Quality
Huperzine · 100 mcgAlpha-GPC · 200 mg

Bacopa, Alpha-GPC, acetyl-L-carnitine, phosphatidylserine, ginkgo, rhodiola, and huperzine create a broad nootropic stack for memory, processing, stress, and cholinergic signaling. The formula has much clearer productivity intent than a general multivitamin.

Bacopa and several supporting actives reach recognizable amounts, but missing standardization and modest Alpha-GPC, carnitine, ginkgo, and rhodiola doses limit depth. Huperzine adds potency and also makes routine continuous use less straightforward.

Study evidence
Alpha-GPC Supportive 2 studies
Bacopa Supportive 12 studies
Ginkgo Supportive 20 studies
Ginkgo Supportive 12 studies
Huperzine No effect 1 study
Rhodiola Supportive 7 studies
Energy
Impact
High effect
B- Goal FitC Strength of SupportC+ CoverageB Formula Quality

Rhodiola, acetyl-L-carnitine, Alpha-GPC, bacopa, phosphatidylserine, and ginkgo support stress resilience, mitochondrial substrate handling, and cognitive focus. The formula covers multiple non-stimulant pathways relevant to mental fatigue.

Rhodiola and acetyl-L-carnitine are modest, and the rhodiola active percentages are not disclosed. Several cognitive ingredients are better aligned with memory support than a direct, noticeable energy effect.

Study evidence
Rhodiola Supportive 18 studies

Ingredients

IngredientAmount per serving
Bacopa Monnieri Extract (Bacosides)
300 mg
Alpha-GPC
200 mg
N-Acetyl-L Carnitine HCl
150 mg
Phosphatidylserine
100 mg
Ginkgo Biloba Leaf Extract (Glycosides, Lactones)
100 mg
Rhodiola rosea Extract (Rosavins, Salidrosides)
100 mg
Huperzine A
100 mcg
Gluten Free Adults 18–50 Vegan Women Vegetarian
Report overview
Huperzine · 100 mcg OverallScore80
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA- Value

The clearly stated 100 mcg Huperzine A amount fits the targeted range, but its botanical source and extract standardization are absent. Capsule delivery supports precise dosing, while no cycling guidance addresses long-half-life accumulation. Alpha-GPC, bacopa, phosphatidylserine, acetyl-L-carnitine, ginkgo, and Rhodiola create a high-quality nootropic stack that strengthens value.

B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Rhodiola rosea is verified, and both rosavins and salidrosides are named, but their percentages and ratio are missing. The clearly disclosed 100 mg extract amount works as a supporting component rather than a full stand-alone dose. A very high cost per standardized amount weakens value despite the useful species and marker information.

Bacopa (Bacosides) · 300 mg OverallScore41
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyD+ Value

The 300 mg bacopa extract reaches a well-researched dose range, but the label does not disclose the bacoside percentage. No plant part or clinically backed branded extract is identified, which limits confidence in consistency and active yield. Ginkgo may raise bleeding risk with anticoagulant or antiplatelet medicines, while huperzine A may add cholinergic side effects.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes.
    Łuszczak J; Kocki J · Annals of agricultural and environmental medicine : AAEM · 2026
    Systematic review19 studies pooledStress Relief Cognitive Support forRhodiola
  2. The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence.
    Ivanova Stojcheva E; Quintela JC · Molecules (Basel, Switzerland) · 2022
    Narrative reviewStress Relief Productivity Boost forRhodiola
  3. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.
    Sarris J; Ravindran A; Yatham LN; Marx W; Rucklidge JJ; McIntyre RS; Akhondzadeh S; Benedetti F; Caneo C; Cramer H; Cribb L; de Manincor M; Dean O; Deslandes AC; Freeman MP; Gangadhar B; Harvey BH; Kasper S; Lake J; Lopresti A; Lu L; Metri NJ; Mischoulon D; Ng CH; Nishi D; Rahimi R; Seedat S; Sinclair J; Su KP; Zhang ZJ; Berk M · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2022
    Guideline / consensusStress Relief forRhodiola
  4. [Effects of rhodiola rosea on oxidative stress and negative emotional states in patients with obstructive sleep apnea].
    Yu HL; Zhang PP; Zhang C; Zhang X; Li ZZ; Li WQ; Fu AS · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2019
    Randomized trial90 participantsStress Relief forRhodiola
  5. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD).
    Bystritsky A; Kerwin L; Feusner JD · Journal of alternative and complementary medicine (New York, N.Y.) · 2008
    Single-arm trial10 participantsStress Relief forRhodiola
  6. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledBrain Health forGinkgo
  7. Ginkgo for elderly people with dementia and age-associated memory impairment: a randomized clinical trial.
    van Dongen M; van Rossum E; Kessels A; Sielhorst H; Knipschild P · Journal of clinical epidemiology · 2003
    Randomized trial214 participantsBrain Health forGinkgo
  8. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledBrain Health Cognitive Support forGinkgo
  9. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
    Kongkeaw C; Dilokthornsakul P; Thanarangsarit P; Limpeanchob N; Norman Scholfield C · Journal of ethnopharmacology · 2014
    Meta-analysis518 participants9 studies pooledBrain Health Mental Focus Productivity Boost forBacopa
  10. Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis.
    Tiemtad P; Ingkaninan K; Temkitthawon P; Thimkorn P; Rattanachaisit N; Teaktong T; Dhippayom T · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
    Meta-analysis2,107 participants29 studies pooledBrain Health Cognitive Support Mental Focus forBacopa
  11. The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects.
    Nathan PJ; Clarke J; Lloyd J; Hutchison CW; Downey L; Stough C · Human psychopharmacology · 2019
    Randomized trial38 participantsBrain Health Cognitive Support forBacopa
  12. Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
    Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
    Meta-analysis8 studies pooledBrain Health Cognitive Support forAlpha-GPC
  13. Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
    Lee W; Kim M · Medicine · 2024
    Randomized trial119 participantsCognitive Support Brain Health forAlpha-GPC
  14. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsBrain Health Cognitive Support forAlpha-GPC
  15. [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial].
    Zhang Z; Wang X; Chen Q; Shu L; Wang J; Shan G · Zhonghua yi xue za zhi · 2002
    Randomized trial202 participantsBrain Health Cognitive Support forHuperzine
  16. Huperzine a in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis.
    Xing SH; Zhu CX; Zhang R; An L · Evidence-based complementary and alternative medicine : eCAM · 2014
    Meta-analysis825 participants10 studies pooledBrain Health Cognitive Support forHuperzine
  17. Huperzine A for the treatment of cognitive, mood, and functional deficits after moderate and severe TBI (HUP-TBI): results of a Phase II randomized controlled pilot study: implications for understanding the placebo effect.
    Zafonte RD; Fregni F; Bergin MJG; Goldstein R; Boudreau N; Monge I; Luz M; Frazier J; Giacino JT · Brain injury · 2021
    Randomized trialBrain Health forHuperzine
  18. Ginkgo biloba for cognitive impairment and dementia.
    Wieland LS; Ludeman E; Chi Y; Feinberg TM; Chen IH; Chen KH; Zhu Y; Wolverson E; Amri H · The Cochrane database of systematic reviews · 2026
    Meta-analysis10,613 participants82 studies pooledCognitive Support forGinkgo
  19. Ginkgo biloba Extract (EGb761), Cholinesterase Inhibitors, and Memantine for the Treatment of Mild-to-Moderate Alzheimer's Disease: A Network Meta-Analysis.
    Thancharoen O; Limwattananon C; Waleekhachonloet O; Rattanachotphanit T; Limwattananon P; Limpawattana P · Drugs & aging · 2019
    Meta-analysisCognitive Support forGinkgo
  20. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
    Pase MP; Kean J; Sarris J; Neale C; Scholey AB; Stough C · Journal of alternative and complementary medicine (New York, N.Y.) · 2012
    Systematic review6 studies pooledCognitive Support Productivity Boost forBacopa
  21. Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment.
    Raghav S; Singh H; Dalal PK; Srivastava JS; Asthana OP · Indian journal of psychiatry · 2011
    Randomized trialCognitive Support forBacopa
  22. Effect of Choline Alfoscerate on the Progression From Mild Cognitive Impairment to Dementia: Distributed Network Analysis of a Multicenter Korean Database Using a Common Data Model.
    Pyun JM; Lee I; Lee K; Kim MH; Park C; Yang HJ · Dementia and neurocognitive disorders · 2024
    Cohort study3,062 participantsCognitive Support forAlpha-GPC
  23. A phase II trial of huperzine A in mild to moderate Alzheimer disease.
    Rafii MS; Walsh S; Little JT; Behan K; Reynolds B; Ward C; Jin S; Thomas R; Aisen PS; Alzheimer's Disease Cooperative Study · Neurology · 2011
    Randomized trial210 participantsCognitive Support forHuperzine
  24. Huperzine A for vascular dementia.
    Hao Z; Liu M; Liu Z; Lv D · The Cochrane database of systematic reviews · 2009
    Systematic review14 participants1 studies pooledCognitive Support forHuperzine
  25. Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
    Kerksick CM · Nutrients · 2024
    Randomized trial20 participantsBrain Health Mental Focus Productivity Boost forAlpha-GPC
  26. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsBrain Health forAlpha-GPC
  27. Comparative efficacy of Medhya Rasayana,Bacopa monnieri, and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: A prakriti-based double-blind, randomized controlled trial.
    Verma J; Rathi R; Anamika; Rathi B; Pandey VB · Journal of Ayurveda and integrative medicine · 2025
    Randomized trial180 participantsBrain Health Cognitive Support forBacopa
  28. Plant-derived nootropics and human cognition: A systematic review.
    Lorca C; Mulet M; Arévalo-Caro C; Sanchez MÁ; Perez A; Perrino M; Bach-Faig A; Aguilar-Martínez A; Vilella E; Gallart-Palau X; Serra A · Critical reviews in food science and nutrition · 2023
    Systematic review256 studies pooledBrain Health forBacopa
  29. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
    Feng X; Fan S; Wei F · Frontiers in pharmacology · 2026
    Meta-analysis1,861 participants25 studies pooledBrain Health Cognitive Support forBacopa
  30. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledBrain Health Productivity Boost forGinkgo
  31. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  32. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  33. Huperzine A associated with improved early postoperative cognitive function after neurosurgery under general anesthesia: a randomized clinical trial.
    Zhang Z; Shen Y; Li J; Tang Y; Zhou P; Ying T; Mo R; Ru Z; Zhao G; Zhu J; Li S; Zhao H · International journal of surgery (London, England) · 2026
    Randomized trial123 participantsBrain Health Cognitive Support forHuperzine
  34. Treatment with Huperzine A improves cognition in vascular dementia patients.
    Xu ZQ; Liang XM; Juan-Wu; Zhang YF; Zhu CX; Jiang XJ · Cell biochemistry and biophysics · 2012
    Randomized trial78 participantsBrain Health forHuperzine
  35. Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer's disease.
    Gul A; Bakht J; Mehmood F · Journal of the Chinese Medical Association : JCMA · 2019
    Randomized trial100 participantsBrain Health forHuperzine
  36. Dose-Response Effects of Short-Term Rhodiola rosea (Golden Root Extract) Supplementation on Anaerobic Exercise Performance and Cognitive Function in Resistance-Trained Athletes: A Randomized, Crossover, Double-Blind, and Placebo-Controlled Study.
    Koozehchian MS; Newton AT; Mabrey G; Bonness FM; Rafajlovska R; Naderi A · Nutrients · 2025
    Randomized trial27 participantsBrain Health Mental Focus forRhodiola
  37. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers.
    Boyle NB; Billington J; Lawton C; Quadt F; Dye L · Nutritional neuroscience · 2022
    Randomized trial100 participantsBrain Health forRhodiola
  38. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
    Panossian A; Wikman G; Sarris J · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2010
    Narrative reviewBrain Health forRhodiola
  39. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
    Darbinyan V; Kteyan A; Panossian A; Gabrielian E; Wikman G; Wagner H · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2001
    Randomized trial56 participantsBrain Health Productivity Boost forRhodiola
  40. Effects of a Rhodiola rosea extract on mental resource allocation and attention: An event-related potential dual task study.
    Koop T; Dienel A; Heldmann M; Münte TF · Phytotherapy research : PTR · 2021
    Single-arm trial50 participantsBrain Health Cognitive Support forRhodiola
  41. [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
    Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
    Meta-analysis10 studies pooledCognitive Support forAlpha-GPC
  42. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
    Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
    Cohort study7,659 participantsCognitive Support forAlpha-GPC
  43. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations.
    Kean JD; Downey LA; Stough C · Complementary therapies in medicine · 2017
    Systematic review5 studies pooledCognitive Support forBacopa
  44. Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.
    Kumar N; Abichandani LG; Thawani V; Gharpure KJ; Naidu MU; Venkat Ramana G · Evidence-based complementary and alternative medicine : eCAM · 2024
    Randomized trial60 participantsCognitive Support forBacopa
  45. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  46. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support Productivity Boost forGinkgo
  47. Alleviating neuropsychiatric symptoms in dementia: the effects of Ginkgo biloba extract EGb 761. Findings from a randomized controlled trial.
    Bachinskaya N; Hoerr R; Ihl R · Neuropsychiatric disease and treatment · 2011
    Randomized trial410 participantsCognitive Support forGinkgo
  48. Efficacy and safety of a once-daily formulation of Ginkgo biloba extract EGb 761 in dementia with neuropsychiatric features: a randomized controlled trial.
    Ihl R; Bachinskaya N; Korczyn AD; Vakhapova V; Tribanek M; Hoerr R; Napryeyenko O; GOTADAY Study Group · International journal of geriatric psychiatry · 2013
    Randomized trial410 participantsCognitive Support forGinkgo
  49. Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis.
    Zheng W; Xiang YQ; Li XB; Ungvari GS; Chiu HF; Sun F; D'Arcy C; Meng X; Xiang YT · Human psychopharmacology · 2017
    Meta-analysis1,117 participants12 studies pooledCognitive Support forHuperzine
  50. [Drug evaluation of huperzine A in the treatment of senile memory disorders].
    Zhang RW; Tang XC; Han YY; Sang GW; Zhang YD; Ma YX; Zhang CL; Yang RM · Zhongguo yao li xue bao = Acta pharmacologica Sinica · 1992
    Randomized trial56 participantsCognitive Support forHuperzine
  51. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
    Panossian A; Wikman G · Current clinical pharmacology · 2009
    Narrative reviewCognitive Support Mental Focus forRhodiola
  52. Central additive effect of Ginkgo biloba and Rhodiola rosea on psychomotor vigilance task and short-term working memory accuracy.
    Al-Kuraishy HM · Journal of intercultural ethnopharmacology · 2016
    Clinical trial112 participantsCognitive Support forRhodiola
  53. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
    Olsson EM; von Schéele B; Panossian AG · Planta medica · 2009
    Randomized trial60 participantsCognitive Support Productivity Boost forRhodiola
  54. The Effect of Short-Term Rhodiola rosea Supplementation on Simulated Game Time, Perceived Fatigue, and Performance in Basketball Players.
    Wang J; Zhao H; Yu L; Zhao K; Jiang W; Liu S; Dai J; Xu L; Sun P; Yun H; Liu C · Nutrients · 2025
    Randomized trial48 participantsEnergy forRhodiola
  55. Effects of Rhodiola rosea on Physical and Decision-Making Performance in Football Players: A Randomised Controlled Trial.
    Dou Y; Wang Y; Zhang W; Jiang Y; Zhang J; Yang T; Han Z; Li Y; Liu C; Ren D · Nutrients · 2026
    Randomized trial24 participantsEnergy Mental Focus forRhodiola
  56. Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.
    Tao B; Sun H; Li H; Xu Z; Xu Y; Chen L; Ma C; Zhang X; Yu L; Bao S; Liu C · Metabolites · 2025
    Randomized trial96 participantsEnergy forRhodiola
  57. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial.
    Lekomtseva Y; Zhukova I; Wacker A · Complementary medicine research · 2019
    Single-arm trial100 participantsEnergy Stress Relief forRhodiola
  58. Combined Rhodiola rosea and eccentric training boost endurance performance and lower-limb reactive strength in recreationally active women.
    Wang IL; Su Y; Zhang L; Tang M; Chen YM · Frontiers in physiology · 2025
    Randomized trial30 participantsEnergy forRhodiola
  59. Evaluating the effects of Bacopa monnieri on cognitive performance and sleep quality of patients with mild cognitive impairment: A triple-blinded, randomized, placebo-controlled trial.
    Delfan M; Kordestani-Moghaddam P; Gholami M; Kazemi K; Mohammadi R · Explore (New York, N.Y.) · 2024
    Randomized trial62 participantsMental Focus forBacopa
  60. Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: a review and comparison of effect sizes.
    Neale C; Camfield D; Reay J; Stough C; Scholey A · British journal of clinical pharmacology · 2013
    Systematic reviewMental Focus forBacopa
  61. Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic Review.
    Al Shahab S; Al Balushi R; Qambar A; Abdulla R; Qader M; Abdulla S; Jahrami H · Nutrients · 2025
    Systematic reviewMental Focus forBacopa
  62. Ginkgo biloba Extract EGb 761 in the Treatment of Patients with Mild Neurocognitive Impairment: A Systematic Review.
    Hort J; Duning T; Hoerr R · Neuropsychiatric disease and treatment · 2023
    Systematic review946 participants9 studies pooledMental Focus forGinkgo
  63. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Randomized trial216 participantsMental Focus forGinkgo
  64. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia.
    Kanowski S; Herrmann WM; Stephan K; Wierich W; Hörr R · Pharmacopsychiatry · 1996
    Randomized trial216 participantsMental Focus forGinkgo
  65. Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.
    Li S; Zhang X; Fang Q; Zhou J; Zhang M; Wang H; Chen Y; Xu B; Wu Y; Qian L; Xu Y · Stroke and vascular neurology · 2021
    Randomized trial348 participantsMental Focus forGinkgo
  66. Ginkgo biloba in the Aging Process: A Narrative Review.
    Barbalho SM; Direito R; Laurindo LF; Marton LT; Guiguer EL; Goulart RA; Tofano RJ; Carvalho ACA; Flato UAP; Capelluppi Tofano VA; Detregiachi CRP; Bueno PCS; Girio RSJ; Araújo AC · Antioxidants (Basel, Switzerland) · 2024
    Narrative review14 studies pooledMental Focus forGinkgo
  67. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials.
    Hung SK; Perry R; Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Systematic review11 studies pooledMental Focus forRhodiola
  68. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men.
    Jówko E; Sadowski J; Długołęcka B; Gierczuk D; Opaszowski B; Cieśliński I · Journal of sport and health science · 2022
    Randomized trial26 participantsMental Focus Productivity Boost forRhodiola
  69. Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer's Disease
    Anna Carotenuto, Angiola Maria Fasanaro, Valentino Manzo, Francesco Amenta, Enea Traini · Journal of Alzheimer's disease reports · 2022
    Randomized trial90 participantsMood Support forAlpha-GPC
  70. The Effects of a Bacopa monnieri Extract (Bacumen®) on Cognition, Stress, and Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lopresti AL; Smith SJ · Clinical drug investigation · 2025
    Randomized trial101 participantsMood Support forBacopa
  71. Effects of Bacopa monnieri (CDRI 08®) in a population of males exhibiting inattention and hyperactivity aged 6 to 14 years: A randomized, double-blind, placebo-controlled trial.
    Kean JD; Downey LA; Sarris J; Kaufman J; Zangara A; Stough C · Phytotherapy research : PTR · 2022
    Randomized trial112 participantsMood Support forBacopa
  72. The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects.
    Stough C; Lloyd J; Clarke J; Downey LA; Hutchison CW; Rodgers T; Nathan PJ · Psychopharmacology · 2001
    Randomized trial85 participantsMood Support Stress Relief forBacopa
  73. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
    Calabrese C; Gregory WL; Leo M; Kraemer D; Bone K; Oken B · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
    Randomized trial54 participantsMood Support Productivity Boost Stress Relief forBacopa
  74. Brahmi for the better? New findings challenging cognition and anti-anxiety effects of Brahmi (Bacopa monniera) in healthy adults.
    Sathyanarayanan V; Thomas T; Einöther SJ; Dobriyal R; Joshi MK; Krishnamachari S · Psychopharmacology · 2013
    Randomized trial72 participantsMood Support forBacopa
  75. Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis.
    Urata M; Sakurai H; Ueno F; Maruki T; Tada T; Uchida T; Matsumoto Y; Murao M; Tomita M; Baba H; Kato M; Tsuboi T; Watanabe K · Neuropsychopharmacology reports · 2025
    Meta-analysis1,049 participants2 studies pooledMood Support forRhodiola
  76. The Effect of Acute Rhodiola rosea Ingestion on Exercise Heart Rate, Substrate Utilisation, Mood State, and Perceptions of Exertion, Arousal, and Pleasure/Displeasure in Active Men.
    Duncan MJ; Clarke ND · Journal of sports medicine (Hindawi Publishing Corporation) · 2015
    Clinical trial10 participantsMood Support forRhodiola
  77. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.
    Sarris J; Panossian A; Schweitzer I; Stough C; Scholey A · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2012
    Systematic review66 studies pooledMood Support forRhodiola
  78. Medicinal Plants in the Treatment of Depression. II: Evidence from Clinical Trials.
    Moragrega I; Ríos JL · Planta medica · 2022
    Systematic reviewMood Support forRhodiola
  79. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms.
    Kasper S; Dienel A · Neuropsychiatric disease and treatment · 2020
    Single-arm trial118 participantsMood Support forRhodiola
  80. Treatment of dementia with neurotransmission modulation.
    Doggrell SA; Evans S · Expert opinion on investigational drugs · 2004
    Narrative reviewProductivity Boost forAlpha-GPC
  81. Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial.
    Stough C; Downey LA; Lloyd J; Silber B; Redman S; Hutchison C; Wesnes K; Nathan PJ · Phytotherapy research : PTR · 2009
    Randomized trial107 participantsProductivity Boost forBacopa
  82. An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance.
    Downey LA; Kean J; Nemeh F; Lau A; Poll A; Gregory R; Murray M; Rourke J; Patak B; Pase MP; Zangara A; Lomas J; Scholey A; Stough C · Phytotherapy research : PTR · 2014
    Randomized trial24 participantsProductivity Boost forBacopa
  83. [Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
    Kasper S; Schubert H · Fortschritte der Neurologie-Psychiatrie · 2009
    Meta-analysis10 studies pooledProductivity Boost forGinkgo
  84. Dietary Flavonoids and Human Cognition: A Meta-Analysis.
    Cheng N; Bell L; Lamport DJ; Williams CM · Molecular nutrition & food research · 2022
    Meta-analysis5,519 participants80 studies pooledProductivity Boost forGinkgo
  85. Limited cognitive benefits in Stage +2 postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
    Elsabagh S; Hartley DE; File SE · Journal of psychopharmacology (Oxford, England) · 2005
    Randomized trial87 participantsProductivity Boost forGinkgo
  86. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial.
    Gavrilova SI; Preuss UW; Wong JW; Hoerr R; Kaschel R; Bachinskaya N; GIMCIPlus Study Group · International journal of geriatric psychiatry · 2015
    Randomized trial160 participantsProductivity Boost forGinkgo
  87. Modulation of cognitive performance following single doses of 120 mg Ginkgo biloba extract administered to healthy young volunteers.
    Kennedy DO; Jackson PA; Haskell CF; Scholey AB · Human psychopharmacology · 2008
    Randomized trial78 participantsProductivity Boost forGinkgo
  88. Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial.
    Wessinger CM; Inman CL; Weinstock J; Weiss EP · International journal of exercise science · 2025
    Randomized trial15 participantsProductivity Boost forHuperzine
  89. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
    Spasov AA; Wikman GK; Mandrikov VB; Mironova IA; Neumoin VV · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2000
    Randomized trialProductivity Boost forRhodiola
  90. Efficacy of Brahmi vati in generalised anxiety disorder - Randomized double blind comparative clinical trial.
    Khot SG; Tubaki BR; Gonugade VB · Journal of Ayurveda and integrative medicine · 2022
    Randomized trial56 participantsStress Relief forBacopa
  91. An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood.
    Benson S; Downey LA; Stough C; Wetherell M; Zangara A; Scholey A · Phytotherapy research : PTR · 2014
    Randomized trial17 participantsStress Relief forBacopa
  92. Herbal remedies for anxiety - a systematic review of controlled clinical trials.
    Ernst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2006
    Systematic review8 studies pooledStress Relief forBacopa
  93. Stress management and the role of Rhodiola rosea: a review.
    Anghelescu IG; Edwards D; Seifritz E; Kasper S · International journal of psychiatry in clinical practice · 2019
    Narrative reviewStress Relief forRhodiola
  94. Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
    Sarris J; McIntyre E; Camfield DA · CNS drugs · 2013
    Narrative reviewStress Relief forRhodiola