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CoQ10 with Tocotrienols 100 mg

Swanson
4.8
★ ★ ★ ★ ★
(374 ratings)
Coenzyme Q-10 100 mg
Product Image
Score84
A well-paired ubiquinone and tocotrienol softgel with good antioxidant context. It remains a maintenance-dose CoQ10 product rather than a high-potency option.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Heart Health
Cardiovascular Support
Metabolism Boost
Anti-Aging
Anti-Inflammatory Support
Energy

Score 84

A well-paired ubiquinone and tocotrienol softgel with good antioxidant context. It remains a maintenance-dose CoQ10 product rather than a high-potency option.
How scoring works
$16.99($0.28 per serving)
iHerb
$ 16.99
iHerb
$ 16.99
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Analysis

The softgel supplies 100 mg of natural ubiquinone for cellular-energy and cardiovascular support. EVNol tocotrienols add a distinct vitamin E-related antioxidant component rather than an unrelated filler.

The lipid-compatible format supports both fat-soluble actives. Tocotrienol quantity is modest, and the exact carrier oil and remaining excipients are not shown.

The product fits users who want CoQ10 with a complementary antioxidant in one softgel. People focused only on CoQ10 absorption may still prefer ubiquinol.

Who is it for
  • Adults seeking CoQ10 with tocotrienols
  • People focused on energy and antioxidant support
  • Users who prefer combined softgels
Best for
  • Daily mitochondrial maintenance
  • Cardiovascular and antioxidant routines
  • Avoiding a separate tocotrienol product

Pros

  • Clearly identifies ubiquinone
  • Adds named EVNol tocotrienols
  • Softgel suits both fat-soluble actives

Cons

  • CoQ10 amount is maintenance-level
  • Carrier oil is not disclosed
  • Ubiquinone may be less readily absorbed than ubiquinol

Warnings

  • CoQ10 may reduce warfarin response, while tocotrienols may affect bleeding tendency; anticoagulant users need prescriber review.
  • CoQ10 may add to the effect of blood-pressure medicines.

Nutrient quality

88 Highest impact

Ubiquinone and softgel delivery provide good practical form quality. A useful CoQ10 amount and relevant tocotrienols support a focused formula.

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Ingredient transparency

84 Highest impact

All active amounts are disclosed without a hidden proprietary blend. The molecular form is specific, though complete directions and inactive ingredients are absent.

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Customer satisfaction

70 High impact

The supplied average rating is very strong. A substantial rating base makes the average reasonably dependable, but no detailed experience evidence was supplied.

.

Value for money

92 Highest impact

Serving economics are highly favorable. Formula quality supports the asking price well.

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Report analysis

Goals

Heart Health
Impact
Highest effect
A- Goal FitB Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinone supports cardiac energy at a maintenance amount, while tocotrienols add a complementary antioxidant pathway. The CoQ10 form is established but less readily used than ubiquinol.

Both amounts are clear in one softgel, although the carrier oil and full excipient profile are not supplied. CoQ10 may reduce warfarin's anticoagulant effect, so people using warfarin should discuss the combination with their prescriber.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Cardiovascular Support
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mgVitamin E · 10 mg

CoQ10 supports cardiac energy while full-spectrum tocotrienols add complementary lipid-phase antioxidant protection. Both ingredients use natural sources at clearly disclosed amounts.

Ubiquinone is less readily absorbed than ubiquinol, and the tocotrienol amount is supportive rather than central. CoQ10 can reduce the effect of warfarin and may add to blood-pressure-lowering treatment.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Metabolism Boost
Impact
Highest effect
B- Goal FitB+ Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 and tocotrienols combine mitochondrial energy support with lipid-phase antioxidant protection. The maintenance-level ubiquinone amount and branded tocotrienol complex are clearly disclosed in a softgel.

The combination is coherent but remains focused on cellular energy rather than thermogenesis or glycemic control. CoQ10 may reduce warfarin activity, so users of this anticoagulant need consistent supervised use.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Aging
Impact
High effect
A- Goal FitB Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial energy, while tocotrienols add complementary fat-soluble antioxidant protection. The ubiquinone amount is useful for maintenance, and the softgel supports delivery.

Ubiquinone is less readily absorbed than ubiquinol, and the carrier oil is not identified. The short combination broadens antioxidant coverage without turning into a crowded formula.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Anti-Inflammatory Support
Impact
High effect
B Goal FitB Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mgVitamin E · 10 mg

CoQ10 and tocotrienols provide complementary mitochondrial and lipid-phase antioxidant support that may help moderate inflammatory stress. The combination remains supportive rather than a direct inhibitor of major inflammatory enzymes.

The CoQ10 amount is suitable for maintenance, while ubiquinone is less readily absorbed than ubiquinol. CoQ10 may reduce warfarin’s anticoagulant effect, so people using warfarin should discuss this specific combination with their prescriber.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Energy
Impact
High effect
A- Goal FitB Strength of SupportC- CoverageA- Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports mitochondrial ATP production, and the 100 mg serving provides a meaningful maintenance amount. Ubiquinone is a usable form, though it is generally less readily absorbed than ubiquinol.

The focused formula offers depth in one energy pathway but does not address alertness or stress resilience. CoQ10 may reduce warfarin's anticoagulant effect, so warfarin users should discuss the combination with their prescriber.

Study evidence
Coenzyme Q-10 Supportive 32 studies

Ingredients

IngredientAmount per serving
natural Coenzyme Q10 (Ubiquinone)
100 mg
EVNol natural Full Spectrum Tocotrienol Complex (Palm)
10 mg
Adults 18–50
Report overview
C+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA Value

The 100 mg ubiquinone dose supports general maintenance, and the softgel should aid delivery of this fat-soluble ingredient. Added tocotrienols provide an antioxidant cofactor, while the exact lipid carrier and excipient profile remain undisclosed. The cost per amount is competitive but sits just above the lowest ubiquinone benchmark.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis.
    Sahebkar A; Simental-Mendía LE; Stefanutti C; Pirro M · Pharmacological research · 2016
    Meta-analysis409 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  4. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  5. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  6. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  7. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  8. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  10. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  11. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  12. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  13. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  14. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  15. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  16. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  17. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  18. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  19. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  20. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  21. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  22. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  23. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  24. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  25. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  26. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  27. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  28. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  29. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  30. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  31. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  32. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  33. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10