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Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg

Life Extension
4.7
★ ★ ★ ★ ★
(7900 ratings)
Coenzyme Q-10 100 mg
Shilajit 100 mg
Product Image
Score85
A balanced, well-delivered ubiquinol and shilajit formula with strong transparency and only limited pathway breadth.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Cardiovascular Support
Heart Health
Energy
Anti-Aging
Metabolism Boost
Anti-Inflammatory Support

Score 85

A balanced, well-delivered ubiquinol and shilajit formula with strong transparency and only limited pathway breadth.
How scoring works

Also available as

4 options
50.00mg • 100 Softgel(s) servings Coenzyme Q-10 50 mg, Shilajit 50 mg • 100 Softgel(s) • 100 servings $39.00 ($0.39 per serving) 50.00mg • 30 Softgel(s) servings Coenzyme Q-10 50 mg, Shilajit 50 mg • 30 Softgel(s) • 30 servings $14.25 ($0.47 per serving) 30 servings Coenzyme Q-10 100 mg, Shilajit 100 mg • 30 Softgel(s) • 30 servings $22.50 ($0.75 per serving) 200.00mg • 30 Softgel(s) servings Coenzyme Q-10 200 mg, Shilajit 200 mg • 30 Softgel(s) • 30 servings $38.80 ($1.29 per serving)
$36.97($0.61 per serving)
iHerb
$ 47.25
Vitacost
$ 42.03
Amazon
$ 36.97
Pure Formulas
$ 42.00
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Analysis

The serving combines 100 mg of ubiquinol with 100 mg of PrimaVie shilajit complex. Both ingredients are meaningfully dosed for a focused cellular-energy formula.

Fat in the softgel supports delivery of the fat-soluble CoQ10. Clear amounts and a simple design also make the product easier to assess than a proprietary blend.

The formula fits sustained energy and cardiac mitochondrial support without stimulants. Its limitation is breadth, since it does not target lipid balance, vascular tone, or other major cardiovascular pathways.

Who is it for
  • Adults seeking daily mitochondrial support
  • People who want a moderate ubiquinol amount
  • Users preferring a fat-containing softgel
Best for
  • Stimulant-free energy support
  • Cardiac cellular energy
  • Balanced CoQ10 and shilajit dosing

Pros

  • Meaningful ubiquinol amount
  • Fat-containing softgel
  • Clearly disclosed branded shilajit

Cons

  • Focused on only two actives
  • Does not cover lipid or vascular pathways
  • Shilajit evidence is less established than CoQ10 evidence

Warnings

  • CoQ10 may reduce warfarin's anticoagulant effect
  • Monitor blood pressure with antihypertensive medicines
  • Shilajit may cause digestive discomfort in sensitive users

Nutrient quality

95 Highest impact

Ubiquinol in a fat-containing softgel is a well-absorbed CoQ10 form, and branded shilajit adds defined support. Both ubiquinol and shilajit have meaningful amounts for the mitochondrial concept.

Ingredient transparency

80 High impact

Every listed active has a specific amount. The provided facts omit a complete capsule or softgel excipient list.

Customer satisfaction

73 High impact

The supplied aggregate rating is very strong. No specific review comments are provided to assess whether negative complaints repeat.

Value for money

91 Highest impact

Strong form, delivery, and dosing support high formula quality. The moderate recurring cost offers good value for premium ubiquinol delivery.

Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA+ Strength of SupportB+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports cardiac mitochondrial energy and antioxidant protection. Human evidence supports CoQ10 for several cardiovascular measures, although results vary by population and condition.

The 100 mg ubiquinol amount falls within a well-supported cardiovascular range. Ubiquinol, shilajit, and their amounts are clear, while the fat-containing softgel supports absorption. CoQ10 may reduce the anticoagulant effect of warfarin.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Heart Health
Heart Health
Impact
Highest effect
A+ Goal FitA+ Strength of SupportB- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports cardiac mitochondrial energy and antioxidant protection. It provides 100 mg of ubiquinol with 100 mg of branded shilajit complex for the stated purpose.

The focused formula does not address lipid balance or vascular tone. CoQ10 may reduce warfarin’s anticoagulant effect and should be monitored when used together.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Energy
Energy
Impact
Highest effect
A Goal FitA+ Strength of SupportB CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol provides a well-aligned amount of a readily used CoQ10 form for mitochondrial energy production. Shilajit adds a complementary mitochondrial-support ingredient rather than a token extra.

The fat-containing softgel is well suited to the absorption needs of CoQ10. Its focused design supports cellular energy without relying on stimulants or opaque blends.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
B+ Goal FitA Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy and antioxidant defenses, while shilajit is intended to complement cellular-energy pathways. Human evidence is useful for CoQ10 in selected age-related cardiovascular settings, but shilajit has less robust validation.

The 100 mg ubiquinol amount uses a preferred bioavailable form, and shilajit is supplied at the same amount. The focused combination covers mitochondrial function well but does not address structural aging, glycation, or neurological preservation broadly.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol supports mitochondrial energy production at a well-supported amount. It may support energy efficiency but is not a direct thermogenic stimulant.

A fat-containing softgel supports absorption and shilajit adds a complementary mitochondrial cofactor. Both active amounts are clearly disclosed.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C Goal FitB+ Strength of SupportC CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol and a branded shilajit complex provide mitochondrial and antioxidant support that may reduce oxidative signals linked to inflammation. Their relevance is supportive rather than as direct as omega-3 fats or targeted anti-inflammatory botanicals.

Both actives are supplied at 100 mg, giving the formula reasonable depth for its mitochondrial purpose. Shilajit composition is not fully described, and direct human anti-inflammatory evidence for the pair remains limited.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Ubiquinol
100 mg
PrimaVie Shilajit Fulvic Acid Complex
100 mg
Gluten Free Adults 18–50
Report overview
Coenzyme Q-10 · 100 mg OverallScore92
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

Ubiquinol reaches a strong target amount in a fat-containing softgel. Shilajit provides an additional cofactor while the label remains clear and convenient. The serving cost is near the collection median and reasonable for the combined formula.

View ingredientView products
Loading alternative details
83 Performance

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 200 mg

Life Extension
<p>The ingredient-focused formula provides 200 mg each of ubiquinol and PrimaVie shilajit in a fat-containing formula. Compared with the original, it raises the CoQ10 amount, raises the shilajit amount.</p>
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
<p>The ingredient-focused formula provides a clearly disclosed 200 mg ubiquinol dose. Compared with the original, it raises the CoQ10 amount, omits shilajit.</p>
80 Performance

CoQ10 & BioPQQ with Shilajit

Global Healing Center
<p>The ingredient-focused formula provides 150 mg of Kaneka ubiquinol, 85 mg of purified PrimaVie shilajit, and 10 mg of BioPQQ. Compared with the original, it raises the CoQ10 amount, uses less shilajit, adds PQQ.</p>
82 Budget

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 50 mg

Life Extension
<p>A lower-cost serving provides 50 mg each of ubiquinol and PrimaVie shilajit. Compared with the original, it uses a lower CoQ10 amount, uses less shilajit.</p>
87 Budget

Mega CoQ10 Ubiquinol 100 mg

Qunol
<p>A lower-cost serving provides 100 mg of ubiquinol with a small amount of ascorbyl palmitate. Compared with the original, it keeps the same CoQ10 amount, omits shilajit.</p>
79 Budget

Shilajit

Paradise
<p>A lower-cost serving provides 250 mg of Himalayan shilajit extract in a single-ingredient formula. Compared with the original, it omits CoQ10, raises the shilajit amount.</p>
87 Value

QH-absorb 100 mg

Jarrow Formulas
<p>A cost-effective serving provides a simple 100 mg ubiquinol formula. Compared with the original, it keeps the same CoQ10 amount, omits shilajit.</p>
87 Value

CoQ10 200 mg

California Gold Nutrition
<p>A cost-effective serving provides a clearly disclosed 200 mg ubiquinone dose. Compared with the original, it raises the CoQ10 amount, omits shilajit, uses ubiquinone rather than ubiquinol.</p>
83 Value

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
<p>A cost-effective serving provides 100 mg of ubiquinone with a small amount of black pepper extract. Compared with the original, it keeps the same CoQ10 amount, omits shilajit, uses ubiquinone rather than ubiquinol.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  3. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  4. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost Heart Health forCoenzyme Q-10
  5. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsMetabolism Boost Anti-Aging forCoenzyme Q-10
  6. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  7. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  8. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  10. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  11. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  12. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  13. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  14. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  15. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  16. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  17. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  18. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  19. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  20. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  21. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  22. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  23. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  24. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  25. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  26. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  27. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  28. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  29. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  30. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10