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Co-QH2 Ubiquinol 100 mg

Carlson
4.8
★ ★ ★ ★ ★
(329 ratings)
Coenzyme Q-10 100 mg
Product Image
Score84
A well-formulated 100 mg reduced CoQ10 softgel in a practical larger supply. Cost remains its main trade-off.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Heart Health
Cardiovascular Support
Anti-Aging
Energy
Anti-Inflammatory Support
Metabolism Boost

Score 84

A well-formulated 100 mg reduced CoQ10 softgel in a practical larger supply. Cost remains its main trade-off.
How scoring works

Also available as

1 option
30 servings Coenzyme Q-10 100 mg • 30 Softgel(s) • 30 servings $31.88 ($1.06 per serving)
$50.92($0.84 per serving)
iHerb
$ 50.92
Pure Formulas
$ 50.92
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Analysis

The softgel supplies 100 mg of Co-QH2, clearly identifying reduced CoQ10. That form supports efficient absorption and fits common daily energy and cardiovascular routines.

The one-unit serving is simple, and the softgel suits the active's fat-soluble nature. The supplied data do not state the carrier oil or another delivery technology.

The product fits committed ubiquinol users who value a two-month supply. People focused on value may want to compare other 100 mg ubiquinol softgels with clearer carrier details.

Who is it for
  • Regular ubiquinol users
  • Adults focused on energy or heart support
  • People who prefer larger supplies
Best for
  • Daily mitochondrial support
  • Longer-term cardiovascular routines
  • Single-softgel use

Pros

  • Uses reduced CoQ10
  • Provides a useful 100 mg amount
  • Larger package improves convenience

Cons

  • High recurring cost
  • Carrier oil is not disclosed
  • No added mitochondrial cofactor

Warnings

  • CoQ10 may reduce warfarin response, so use should be coordinated with the prescriber.
  • CoQ10 may add to antihypertensive effects.

Nutrient quality

96 Highest impact

Ubiquinol and softgel delivery provide strong absorption-oriented quality. The focused amount is meaningful without obvious excess or unrelated additions.

.

Ingredient transparency

85 Highest impact

All active amounts are disclosed without a hidden proprietary blend. The molecular form is specific, though complete directions and inactive ingredients are absent.

.

Customer satisfaction

70 High impact

The supplied average rating is very strong. A substantial rating base makes the average reasonably dependable, but no detailed experience evidence was supplied.

.

Value for money

80 High impact

Serving economics are reasonable. Form or dose limitations keep practical value moderate.

.
Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol provides a therapeutically useful amount of the active reduced CoQ10 form. It supports cardiac energy and may be especially relevant when statins lower CoQ10 status.

The one-softgel serving is clear, though the lipid carrier and full excipient profile are not disclosed. CoQ10 may reduce warfarin's anticoagulant effect, so people using warfarin should discuss the combination with their prescriber.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports energy production in heart muscle and may help selected blood-pressure or statin-related needs. The 100 mg reduced CoQ10 amount is clearly disclosed in a fat-compatible softgel.

The formula is focused on cardiac energy and antioxidant protection rather than lipids, circulation, or rhythm support. CoQ10 may reduce warfarin response, so people using warfarin need clinician-guided monitoring if intake changes.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy production and antioxidant protection, making it highly relevant to healthy aging. The reduced form is a practical choice when conversion from standard CoQ10 may be less efficient.

The focused softgel supplies a meaningful amount with full active disclosure. Carrier-oil details are missing, and CoQ10 may alter warfarin response when supplementation starts or stops.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Energy
Energy
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports mitochondrial ATP production, and the 100 mg serving provides a meaningful maintenance amount. The reduced ubiquinol form and softgel delivery support absorption.

The focused formula offers depth in one energy pathway but does not address alertness or stress resilience. CoQ10 may reduce warfarin's anticoagulant effect, so warfarin users should discuss the combination with their prescriber.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitA Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol offers relevant antioxidant and mitochondrial support that may help lower systemic inflammatory signaling. The single-softgel amount sits in a well-researched range.

The reduced CoQ10 form supports absorption and is clearly named. Coverage remains narrow because no complementary immunomodulatory or pathway-targeted active is included.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B- Goal FitA Strength of SupportD CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol provides direct support for mitochondrial energy production and aligns with the cellular-energy side of metabolism. The focused formula is not designed to raise thermogenesis or broadly influence body composition.

The 100 mg amount is well aligned with common CoQ10 use, and the reduced form supports absorption. The active is clearly stated, though the carrier oil and any advanced delivery feature are not disclosed.

Study evidence
Coenzyme Q-10 Disputed 11 studies

Ingredients

IngredientAmount per serving
Co-QH2 (reduced Coenzyme Q10)
 100 mg
Gluten Free Adults 18–50
Report overview
Coenzyme Q-10 (reduced Coenzyme Q10) · 100 mg OverallScore77
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

The reduced CoQ10 form and well-aligned single-softgel amount support good absorption and practical dosing. The softgel format suits a fat-soluble ingredient, but the carrier oil and remaining excipients are not disclosed. The larger count improves convenience, yet the serving remains costly without a documented advanced delivery technology or added cofactor.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
<p>A substantial ubiquinol amount in a softgel provides reduced-form CoQ10 with absorption-aware delivery. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. The amount may be more than needed for basic maintenance.</p>
81 Performance

Ubiquinol Active CoQ10 200 mg

Natural Factors
<p>A substantial ubiquinol amount with organic flaxseed oil combines the reduced form with a lipid carrier. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. Its routine serving cost is comparatively high.</p>
85 Performance

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg

Life Extension
<p>Ubiquinol and a clearly listed shilajit complex provide focused mitochondrial support in a fat-containing softgel. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. Shilajit adds complexity for people seeking CoQ10 alone.</p>
84 Budget

CoQ10 100 mg

Best Naturals
<p>Clearly identified ubiquinone provides a practical maintenance amount in a very economical serving. It lowers routine cost versus the original. The dry capsule has no stated lipid carrier or absorption enhancer.</p>
83 Budget

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
<p>A meaningful ubiquinone amount and softgel delivery provide focused routine support. It lowers routine cost versus the original. Black pepper extract may change exposure to some medicines.</p>
84 Budget

CoQ10 100 mg

California Gold Nutrition
<p>Clearly identified ubiquinone and softgel delivery provide a straightforward maintenance formula. It lowers routine cost versus the original. Complete intake directions and excipient details are not supplied.</p>
87 Value

Mega CoQ10 Ubiquinol 100 mg

Qunol
<p>Ubiquinol in a softgel provides the reduced CoQ10 form at a useful maintenance amount. Its ingredient design and serving economics offer a useful value trade-off versus the original. The small ascorbyl-palmitate addition contributes little to the core purpose.</p>
87 Value

CoQ10 200 mg

California Gold Nutrition
<p>A substantial ubiquinone amount and softgel delivery combine focused dosing with efficient serving value. Its ingredient design and serving economics offer a useful value trade-off versus the original. Full intake directions and excipient details are not supplied.</p>
87 Value

QH-absorb 100 mg

Jarrow Formulas
<p>Ubiquinol in a softgel provides reduced-form CoQ10 at a useful maintenance amount with favorable serving value. Its ingredient design and serving economics offer a useful value trade-off versus the original. The amount is lower than higher-dose targeted formulas.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. Supplementation with coenzyme Q10 reduces plasma lipoprotein(a) concentrations but not other lipid indices: A systematic review and meta-analysis.
    Sahebkar A; Simental-Mendía LE; Stefanutti C; Pirro M · Pharmacological research · 2016
    Meta-analysis409 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  4. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  5. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  6. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  7. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  8. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  10. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  11. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  12. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  13. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  14. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  15. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  16. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  17. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  18. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  19. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  20. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  21. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  22. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  23. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  24. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  25. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  26. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  27. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  28. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  29. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  30. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  31. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  32. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  33. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10