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Melatonin 5 mg

Mason Natural
4.6
★ ★ ★ ★ ★
(1212 ratings)
Melatonin 5 mg
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Score78

Outstanding package value cannot offset a 5 mg dose that may be unnecessarily high for many users.

How scoring works
Quantity:300 Tablet(s) • (300 servings)
Goals:
Sleep Support

Score 78

Outstanding package value cannot offset a 5 mg dose that may be unnecessarily high for many users.

How scoring works
$12.99($0.04 per serving)
Walmart
$ 12.99
Amazon
$ 25.48
iHerb
$ 20.74
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Analysis

Each tablet supplies 5 mg melatonin for direct sleep-timing support. One milligram B6 and 54 mg calcium do not materially deepen the formula.

The melatonin amount may work for established users but is more than many people need. Standard tablets offer no special rapid or sustained-release benefit.

A 300-serving bottle is unusually economical and long-lasting. That large supply is useful only if 5 mg has already proved appropriate for the user.

Who is it for
  • Adults who already tolerate 5 mg
  • Long-term value seekers
  • Users preferring one tablet
Best for
  • Established 5 mg routines
  • Occasional sleep-onset support
  • Very long package duration

Pros

  • Three hundred servings
  • One-tablet serving
  • Clear melatonin amount
  • Very economical use

Cons

  • Five milligrams may be excessive
  • B6 adds little sleep value
  • Calcium amount is modest
  • No modified release

Warnings

  • Five milligrams may cause vivid dreams, headache, or morning grogginess
  • Secure the large bottle away from children
  • Do not combine casually with alcohol or sedative medicines

Nutrient quality

74 High impact

The standard delivery format offers no controlled overnight release. The elevated melatonin amount may be more than some users need.

Ingredient transparency

82 Highest impact

All listed active ingredients have individual amounts and no proprietary blend hides them. Daily directions and the complete inactive-ingredient list are not supplied.

Customer satisfaction

66 High impact

The supplied average is favorable and the aggregate pool is substantial. No specific feedback is provided to assess recurring complaints or whether experience matches the intended use.

Value for money

88 Highest impact

Serving cost is low for the disclosed formula. Supporting additions provide mixed extra value.

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Goals

Sleep Support
Impact
Highest effect
A Goal FitB Strength of SupportC+ CoverageA- Formula Quality
Melatonin · 5 mg

Melatonin gives direct support for sleep timing and falling asleep. The amount is above the lower physiological range and may cause morning drowsiness in sensitive users.

The full dose is clearly contained in one standard tablet. Vitamin B6 and calcium add minor support but do not broaden the formula into a second meaningful sleep pathway.

Study evidence
Melatonin Supportive 181 studies
Vitamin B6 Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
1 mg
Calcium (Dicalcium Phosphate)
54 mg
Melatonin
5 mg
Gluten Free Adults 18–50 Women Vegetarian
Report overview
Melatonin · 5 mg OverallScore62
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

The 5 mg dose is clearly contained in one tablet but sits above the physiological range. Standard hard-tablet delivery offers no rapid or sustained-release advantage. The product is highly cost efficient, although no independent purity seal is documented.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  3. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  4. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  5. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  6. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  9. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  10. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  11. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  12. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  13. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  14. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  15. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6