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Magnesium Caps 500 mg

Life Extension
4.8
★ ★ ★ ★ ★
(80864 ratings)
Magnesium 500 mg
Product Image
Score80
A low-cost, diverse magnesium blend with a premium chelate, held back by oxide and unclear form proportions.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Digestive Health
Energy
Heart Health
Cardiovascular Support
General Health
Bone Health
Stress Relief
Testosterone Support

Score 80

A low-cost, diverse magnesium blend with a premium chelate, held back by oxide and unclear form proportions.
How scoring works
$8.97($0.08 per serving)
iHerb
$ 9.00
Vitacost
$ 9.00
Pure Formulas
$ 9.00
Vitacost
$ 9.00
Walmart
$ 8.97
Amazon
$ 8.97
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Analysis

Three useful forms provide broader absorption potential, led by the branded glycinate chelate and supported by citrate and succinate. Magnesium oxide lowers the average form quality and may contribute disproportionately to digestive effects.

The supplied label data repeat the same amount for every source, so the proportion of each form cannot be judged. A clear elemental total is suggested by the product name, but compound weights and contributions should be distinguished.

The low serving cost and single-capsule format are compelling practical advantages. People prioritizing transparency or a fully premium form may still prefer a simpler bisglycinate product.

Who is it for
  • Adults wanting several magnesium forms in one capsule
  • Budget-focused users who value a branded chelate
Best for
  • Broad magnesium form coverage
  • Low-cost daily capsule routines

Pros

  • Includes TRAACS lysyl glycinate chelate
  • Also provides citrate and succinate
  • Very low serving cost
  • Single-capsule serving

Cons

  • Contains magnesium oxide
  • Form proportions are not disclosed
  • Repeated ingredient amounts make the label hard to interpret
  • No supportive cofactor

Warnings

  • The high named amount and included oxide may cause loose stools or cramping.
  • Verify the elemental total rather than adding the repeated form quantities together.
  • People with impaired kidney function may not clear supplemental magnesium safely.
  • Magnesium can reduce absorption of some antibiotics and thyroid medicine, so follow the prescribed spacing instructions.

Nutrient quality

78 High impact

Several favorable forms support absorption and the amount is clearly substantial. Added oxide and an aggressive supplemental dose reduce tolerability.

Ingredient transparency

78 High impact

The total amount and all four forms are named. Their proportions, full directions, and non-active ingredients are not disclosed.

Customer satisfaction

73 High impact

The aggregate satisfaction metric is strong and supported by a useful volume of ratings. Specific firsthand feedback is absent, so recurring complaints and purpose fit cannot be assessed.

Value for money

94 Highest impact

Multiple favorable forms and a very low serving cost support strong value. The oxide component and aggressive amount are the main quality trade-offs.

Report analysis

Goals

Digestive Health
Impact
Highest effect
A- Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Magnesium · 500 mg

Magnesium citrate, succinate, and a named glycinate chelate provide strong support for motility and mineral absorption, while oxide adds a more stool-loosening effect. The formula is well aligned with occasional constipation but remains limited to one digestive pathway.

The labeled amount is substantial, and the mix includes several favorable forms despite the lower-quality oxide component. The high magnesium serving, particularly with citrate and oxide, may cause loose stools or cramping in sensitive users.

Study evidence
Magnesium Supportive 50 studies
Energy
Impact
Highest effect
A- Goal FitB+ Strength of SupportC CoverageB+ Formula Quality
Magnesium · 500 mg

A substantial magnesium amount supports ATP-dependent enzymes, muscles, and nerves. Citrate, succinate, and a named glycinate chelate improve the overall absorption profile.

Magnesium oxide remains a weaker part of the blend, and the full amount is higher than many routine daily targets. The formula is focused on foundational metabolism rather than immediate stimulation.

Study evidence
Magnesium Supportive 4 studies
Heart Health
Impact
High effect
B Goal FitA- Strength of SupportC CoverageA- Formula Quality
Magnesium · 500 mg

The substantial magnesium amount may support blood-pressure regulation and cardiac function. It provides 500 mg of magnesium from citrate, oxide, succinate, and a TRAACS chelate for the stated purpose.

The mixed formula includes poorly absorbed oxide and does not disclose each form’s share. The 500 mg supplemental magnesium amount may cause diarrhea and can accumulate with impaired kidney function.

Study evidence
Magnesium Supportive 158 studies
Cardiovascular Support
Impact
High effect
A- Goal FitB Strength of SupportC- CoverageB+ Formula Quality
Magnesium · 500 mg

Magnesium directly supports vascular relaxation and stable electrical signaling in the heart. The substantial elemental amount gives this focused formula meaningful cardiovascular relevance.

Citrate, succinate, and a named chelate improve the blend, but magnesium oxide lowers expected absorption. The high amount may also cause loose stools or abdominal discomfort, especially in sensitive users.

Study evidence
Magnesium Supportive 123 studies
General Health
Impact
High effect
A+ Goal FitC+ Strength of SupportD+ CoverageB+ Formula Quality
Magnesium · 500 mg

Magnesium is a foundational mineral with broad roles in energy production, muscle function, and nerve signaling. The 500 mg amount is above the main target range and may cause loose stools, especially because the blend includes oxide and citrate.

A TRAACS glycinate component improves the mixed-form profile, while magnesium oxide lowers expected absorption. The label states the total amount clearly but does not show how much each form contributes.

Study evidence
Magnesium Supportive 114 studies
Bone Health
Impact
High effect
B Goal FitB+ Strength of SupportC- CoverageB Formula Quality
Magnesium · 500 mg

Magnesium contributes to bone mineral structure and remodeling, and the 500 mg amount is substantial. Citrate, succinate, and a named TRAACS chelate improve the blend, while magnesium oxide lowers overall absorption quality.

A single-mineral formula provides depth but lacks calcium, vitamin D, vitamin K, or protein-matrix support. The high magnesium amount may cause loose stools or cramping in sensitive users.

Study evidence
Magnesium Supportive 48 studies

Ingredients

IngredientAmount per serving
Magnesium (Magnesium Citrate, Magnesium Oxide, Magnesium Succinate, TRAACS Magnesium Lysyl Glycinate Chelate)
500 mg
Gluten Free Adults 18–50
Report overview
B Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value

Citrate, succinate, and a named TRAACS glycinate chelate improve the blend, though magnesium oxide lowers its absorption potential. The elemental amount is clear but sits above the main target range, with no supportive cofactor included. A very low serving cost and the patented chelate support strong value despite the mixed forms.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
    van der Schoot A; Creedon A; Whelan K; Dimidi E · Neurogastroenterology and motility · 2023
    Meta-analysis787 participants8 studies pooledDigestive Health forMagnesium
  2. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  3. Effect of the laxative magnesium oxide on gastrointestinal functional recovery in fast-track colonic resection: a double-blind, placebo-controlled randomized study.
    Andersen J; Christensen H; Pachler JH; Hallin M; Thaysen HV; Kehlet H · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2012
    Randomized trial49 participantsDigestive Health forMagnesium
  4. Diagnosis of magnesium-induced diarrhea.
    Fine KD; Santa Ana CA; Fordtran JS · The New England journal of medicine · 1991
    Clinical trial19 participantsDigestive Health forMagnesium
  5. Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation.
    Bu LN; Chang MH; Ni YH; Chen HL; Cheng CC · Pediatrics international : official journal of the Japan Pediatric Society · 2007
    Randomized trial45 participantsDigestive Health forMagnesium
  6. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  7. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  8. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  9. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  10. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  11. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  12. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  13. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  14. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  15. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  16. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  17. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  18. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  19. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  20. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  21. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  22. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  23. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  24. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  25. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  26. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  27. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  28. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  29. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  30. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  31. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  32. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  33. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  34. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  35. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  36. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  37. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  38. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  39. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  40. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  41. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium