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Magnesium Glycinate Chelate

Designs for Health
4.8
★ ★ ★ ★ ★
(332 ratings)
Magnesium 300 mg
Product Image
Score79
A 300 mg branded buffered glycinate serving gives the formula strong quality. Unclear buffer composition and premium cost are the main limitations.
How scoring works
Quantity:120 Capsule(s) • (60 servings)
Goals:
Stress Relief
General Health
Energy
Testosterone Support
Cardiovascular Support
Heart Health
Bone Health
Digestive Health

Score 79

A 300 mg branded buffered glycinate serving gives the formula strong quality. Unclear buffer composition and premium cost are the main limitations.
How scoring works
$33.49($0.55 per serving)
iHerb
$ 33.49
Pure Formulas
$ 33.49
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Analysis

The two-capsule serving provides 300 mg of magnesium from TRAACS buffered glycinate chelate. The form and amount fit users seeking systemic magnesium support without the very high load of 400 to 500 mg products.

Buffering can improve elemental density, but the added magnesium source and its proportion are not disclosed. That omission prevents treating the full amount as unbuffered glycinate.

Sixty servings offer a practical two-month supply. The formula is well focused, though the serving cost remains high compared with simpler chelated alternatives.

Who is it for
  • Adults seeking buffered magnesium glycinate
  • Users who prefer capsules
  • People wanting a two-month supply
Best for
  • Chelated magnesium intake
  • Moderate-to-high magnesium support
  • Focused mineral supplementation

Pros

  • Uses branded TRAACS glycinate chelate
  • Provides 300 mg of magnesium
  • Offers 60 servings
  • Avoids unnecessary active additions

Cons

  • Does not identify the buffer
  • Full excipients are missing
  • Costs more than many alternatives
  • Requires two capsules per serving

Warnings

  • The 300 mg magnesium serving may cause diarrhea, cramping, or nausea, especially when taken at once.
  • Reduced kidney function can impair magnesium clearance, so regular supplemental use requires medical guidance in that situation.
  • Magnesium can reduce absorption of levothyroxine, bisphosphonates, and certain antibiotics; follow the medicine-specific spacing interval.

Nutrient quality

90 Highest impact

Form quality is favorable and the magnesium amount is meaningful. The focused ingredient profile remains aligned with its intended use.

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Ingredient transparency

80 Highest impact

The elemental amount is clearly stated without a hidden key dose. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

66 High impact

The average customer rating is very strong. The rating base is adequate but not especially deep, while specific review experiences were not supplied.

.

Value for money

78 High impact

Serving economics are weak for the supplied amount. Ingredient quality supports good practical value.

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Report analysis

Goals

Stress Relief
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Magnesium · 300 mg

Magnesium glycinate provides a well-absorbed form of a mineral involved in normal nervous-system regulation. The disclosed amount is meaningful, and the patented chelate gives unusually strong form assurance.

The focused formula supports one foundational relaxation pathway rather than cortisol regulation or direct neurotransmitter modulation. Its buffered design is not fully explained, but the product remains much stronger than magnesium oxide-based alternatives.

Study evidence
Magnesium Supportive 13 studies
General Health
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Magnesium · 300 mg

A meaningful magnesium glycinate serving supports normal muscle, nerve, and energy-related functions. The patented chelate and clear elemental amount strengthen confidence in absorption and label quality.

The formula is deliberately narrow and does not fill wider vitamin or fatty-acid gaps. Magnesium can still cause digestive discomfort in some users, although glycinate is often better tolerated than oxide.

Study evidence
Magnesium Supportive 114 studies
Energy
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA Formula Quality
Magnesium · 300 mg

Magnesium supports energy metabolism, muscle function, and normal nerve activity. TRAACS glycinate chelate offers strong absorption potential and controlled chelation quality.

The 300 mg elemental amount is clearly stated and suitable for practical daily supplementation. A focused formula provides meaningful magnesium depth without unrelated extras.

Study evidence
Magnesium Supportive 4 studies
Testosterone Support
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA Formula Quality
Magnesium · 300 mg

Magnesium provides a relevant route to testosterone support. The disclosed amount appears meaningful for that focused role.

The formula remains narrow rather than comprehensive. Magnesium Glycinate Chelate is best viewed as targeted support rather than proof of a clinical benefit.

Study evidence
Magnesium Disputed 5 studies
Cardiovascular Support
Impact
High effect
B Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Magnesium · 300 mg

A meaningful amount of branded magnesium glycinate may support vascular relaxation and normal cardiac rhythm. The buffered form can include less absorbable magnesium, so its quality is not as clear as an unbuffered glycinate.

The formula provides strong depth for one established mineral pathway with no unnecessary additions. Its narrow focus leaves lipid balance, cellular energy, and homocysteine regulation unaddressed.

Study evidence
Magnesium Supportive 123 studies
Heart Health
Impact
High effect
B Goal FitA- Strength of SupportD CoverageA+ Formula Quality
Magnesium · 300 mg

A meaningful amount of branded magnesium glycinate may support vascular relaxation and normal cardiac rhythm. The buffered form can include less absorbable magnesium, so its quality is not as clear as an unbuffered glycinate.

The formula provides strong depth for one established mineral pathway with no unnecessary additions. Its narrow focus leaves lipid balance, cellular energy, and homocysteine regulation unaddressed.

Study evidence
Magnesium Supportive 158 studies

Ingredients

IngredientAmount per serving
Magnesium (TRAACS Magnesium Glycinate Chelate buffered)
300 mg
Gluten Free Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB- Value

The patented glycinate chelate offers strong absorption potential and controlled chelation quality. The elemental amount is clearly disclosed and falls within the standard therapeutic range. The focused formula lacks added cofactors, while the patented material partly justifies its premium cost.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  2. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  3. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  4. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  5. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  6. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  7. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  8. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  9. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  10. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  11. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  12. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  13. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  14. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  15. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  16. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  17. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  18. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  19. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  20. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  21. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  22. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  23. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  24. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  25. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  26. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  27. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  28. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  29. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  30. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  31. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  32. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  33. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  34. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  35. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  36. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  37. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium