Product Image

ProOmega-D

Nordic Naturals
4.7
★ ★ ★ ★ ★
(2110 ratings)
Vitamin D 1000 IU
Omega-3 1280 mg
Product Image
Score74
Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. Missing EPA and DHA amounts, oil form, and quality-verification details reduce dose precision and value confidence.
How scoring works
Quantity:180 Softgel(s) • (90 servings)
Goals:
General Health
Anti-Inflammatory Support
Anti-Aging
Immunity
Skin Health
Energy
Joint Health
Metabolism Boost
Testosterone Support

Score 74

Best suited to general health, with the clearest benefits coming from the disclosed active ingredients. Missing EPA and DHA amounts, oil form, and quality-verification details reduce dose precision and value confidence.
How scoring works

Also available as

1 option
60 servings • Lemon Omega-3 1280 mg • 60 Soft Gel(s) • 30 servings $30.70 ($1.02 per serving)
$80.92($0.89 per serving)
iHerb
$ 80.92
iHerb
$ 80.92
Amazon
$ 80.92
Report prices

Analysis

A substantial total omega-3 serving pairs coherently with vitamin D3 for broad immune, inflammatory, and general-health support. Missing EPA and DHA amounts, oil form, and quality-verification details reduce dose precision and value confidence.

Vitamin D3 and omega-3 fatty acids cover complementary immune, skeletal, and cardiovascular foundations. The serving provides 25 mcg of D3 and a substantial total omega-3 amount in a softgel. The label does not break the omega-3 total into EPA and DHA, limiting dose precision for those actives.

Vitamin D3 is a foundational hormone-related nutrient, while omega-3 fats may support general metabolic health. The 1,000 IU vitamin D amount is below the goal's example target and is most relevant when vitamin D status is low. D3 and concentrated omega-3s form a clean, well-disclosed combination.

Who is it for
  • People seeking general health support
  • People seeking anti-inflammatory support support
  • People seeking anti-aging support
Best for
  • General Health
  • Anti-Inflammatory Support
  • Anti-Aging

Pros

  • A substantial total omega-3 serving pairs coherently with vitamin D3 for broad immune, inflammatory, and general-health support.
  • Vitamin D3 and omega-3 fatty acids cover complementary immune, skeletal, and cardiovascular foundations.
  • The serving provides 25 mcg of D3 and a substantial total omega-3 amount in a softgel.
  • Even with that disclosure gap, the two well-established nutrient classes give the formula useful breadth and depth.
  • A substantial total omega-3 amount directly supports production of inflammation-resolving mediators.

Cons

  • Missing EPA and DHA amounts, oil form, and quality-verification details reduce dose precision and value confidence.
  • The label does not break the omega-3 total into EPA and DHA, limiting dose precision for those actives.
  • The total omega-3 and vitamin D amounts are clear, but EPA and DHA are not separated in the supplied data.
  • Exact EPA and DHA amounts and the oil form are not disclosed, preventing a precise judgment of active depth.
  • The vitamin D amount is useful for maintenance, but the label gives only total omega-3s without an EPA and DHA breakdown.

Warnings

  • People using anticoagulant or antiplatelet therapy should consider the added blood-thinning effect of omega-3s.

Nutrient quality

84 Highest impact

The total omega-3 amount is useful, but source quality and the EPA-to-DHA balance cannot be evaluated. The streamlined formula avoids obvious excess and filler-heavy additions.

Ingredient transparency

65 High impact

Total omega-3 is disclosed, but EPA and DHA amounts are not separated. Daily directions and complete excipient details are not supplied.

Customer satisfaction

73 High impact

The supplied aggregate satisfaction metric is strong and supported by the available feedback volume. No feedback excerpts or complaint themes are supplied, so specific experience patterns cannot be verified.

Value for money

74 High impact

Serving value appears reasonable but not exceptional. The focused ingredient profile avoids costly low-value extras.

Report analysis

Goals

General Health
General Health
Impact
Highest effect
A+ Goal FitA- Strength of SupportB+ CoverageA+ Formula Quality
Vitamin D · 1000 IU

Vitamin D3 and omega-3 fatty acids cover complementary immune, skeletal, and cardiovascular foundations. The serving provides 25 mcg of D3 and a substantial total omega-3 amount in a softgel.

The label does not break the omega-3 total into EPA and DHA, limiting dose precision for those actives. Even with that disclosure gap, the two well-established nutrient classes give the formula useful breadth and depth.

Study evidence
Vitamin D Supportive 115 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A Goal FitB Strength of SupportB CoverageA+ Formula Quality
Vitamin D · 1000 IU

A substantial total omega-3 amount directly supports production of inflammation-resolving mediators. Vitamin D3 adds an immunomodulatory pathway that may matter most when vitamin D status is low.

The total omega-3 and vitamin D amounts are clear, but EPA and DHA are not separated in the supplied data. That omission makes the most clinically relevant fatty-acid dose harder to verify.

Study evidence
Vitamin D Supportive 101 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A Goal FitC+ Strength of SupportB- CoverageA+ Formula Quality
Omega-3 · 1280 mgVitamin D · 1000 IU

Omega-3 fatty acids and vitamin D3 provide broad support for inflammatory balance, cell membranes, cardiovascular aging, and foundational nutrient status. The 1,280 mg omega-3 total is substantial.

Exact EPA and DHA amounts and the oil form are not disclosed, preventing a precise judgment of active depth. Vitamin D3 is clearly identified and forms a sensible companion to the fatty-acid base.

Study evidence
Omega-3 Supportive 56 studies
Vitamin D Supportive 50 studies
Immunity
Immunity
Impact
Highest effect
B Goal FitB+ Strength of SupportB- CoverageA Formula Quality
Vitamin D · 1000 IUOmega-3 · 1280 mg

Vitamin D3 directly supports immune-cell development and signaling, while omega-3 fatty acids may help regulate inflammatory responses. The softgel format suits these fat-soluble ingredients and provides a complementary pairing.

The vitamin D amount is useful for maintenance, but the label gives only total omega-3s without an EPA and DHA breakdown. The formula supports immune balance more than short-term symptom relief and does not provide vitamin C or zinc.

Study evidence
Omega-3 Supportive 24 studies
Vitamin D Supportive 85 studies
Skin Health
Skin Health
Impact
High effect
C+ Goal FitB+ Strength of SupportB- CoverageA Formula Quality
Omega-3 · 1280 mg

Omega-3 fats may support skin barrier function and inflammatory balance, while vitamin D adds secondary foundational support. Evidence for visible skin improvement is less direct than for collagen peptides or targeted ceramides.

The total omega-3 amount is substantial and vitamin D3 is clearly identified. Individual EPA and DHA amounts and the oil’s molecular form are not shown, limiting precision.

Study evidence
Omega-3 Supportive 35 studies
Energy
Energy
Impact
High effect
C+ Goal FitC Strength of SupportC- CoverageA Formula Quality
Vitamin D · 1000 IU

Vitamin D3 and omega-3 fats may support mitochondrial and muscle function but do not provide a direct energy boost. Evidence supports correcting vitamin D deficiency, while general fatigue benefits from fish oil are less consistent.

Vitamin D3 provides a maintenance amount and omega-3 intake is substantial, but neither is a targeted acute-energy dose. The softgel lipid matrix suits both fat-soluble actives and both amounts are clearly disclosed.

Study evidence
Vitamin D Supportive 32 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
2 Gram(s)
Vitamin D3 (Cholecalciferol)
 1000 IU
Total Omega-3 Fatty Acids
1280 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Vitamin D (Cholecalciferol) · 1000 IU OverallScore68
A Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

Vitamin D is supplied as D3, the form generally preferred for maintaining vitamin D status. The 1000 IU serving provides a standard maintenance amount below the preferred range. The softgel provides lipid-based delivery, but independent quality verification is absent and dose-adjusted value is weak.

View ingredientView products
Omega-3 · 1280 mg OverallScore40
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB+ Value

The molecular form, fish source, and antioxidant system are absent from the supplied details. Only total omega-3 is disclosed, though its share of total fat is moderately concentrated. Cost per disclosed active gram is good, but independent purity verification is not stated.

View ingredientView products
Loading alternative details
68 Performance

Ultimate Omega Xtra Lemon

Nordic Naturals
<p>The ingredient profile is well aligned with the original’s omega-3 and vitamin focus, supplying 3400 mg of omega-3s and 25 mcg of vitamin D. Its combined EPA and DHA or total omega-3 amount matches or exceeds the original’s, giving it a strong core fatty-acid profile.</p>
62 Performance

D3 2000 IU

Nature Made
<p>The ingredient profile is well aligned with the original’s omega-3 and vitamin focus, supplying 2000 IU of vitamin D. It preserves the original’s vitamin component but does not disclose a comparable omega-3 amount, so it is not a like-for-like fatty-acid replacement.</p>
61 Performance

Liquid Vitamin D3 Drops 2000 IU Natural Citrus Flavor

Bluebonnet
<p>The ingredient profile is well aligned with the original’s omega-3 and vitamin focus, supplying 2000 IU of vitamin D. It preserves the original’s vitamin component but does not disclose a comparable omega-3 amount, so it is not a like-for-like fatty-acid replacement.</p>
88 Budget

Liquid Vitamin D3 Drops 1000 IU Natural Citrus Flavor

Bluebonnet
<p>A lower cost per serving makes this a practical budget alternative, while it supplies 1000 IU of vitamin D. The input does not provide enough EPA, DHA, or total omega-3 data for a complete dose comparison with the original.</p>
88 Budget

Extra Strength Liquid Vitamin D3

Protocol For Life Balance
<p>A lower cost per serving makes this a practical budget alternative, while it supplies 2000 IU of vitamin D. The input does not provide enough EPA, DHA, or total omega-3 data for a complete dose comparison with the original.</p>
87 Budget

D3 1000 IU

Nature Made
<p>A lower cost per serving makes this a practical budget alternative, while it supplies 1000 IU of vitamin D. The input does not provide enough EPA, DHA, or total omega-3 data for a complete dose comparison with the original.</p>
86 Value

Prenatal DHA Unflavored Formula

Nordic Naturals
<p>Strong serving value is paired with 830 mg of omega-3s and 10 mcg of vitamin D. Its omega-3 amount is lower than the original’s and keeps the available omega-3 amount disclosed, balancing cost-effectiveness with a useful ingredient profile.</p>
82 Value

Liquid Vitamin D3 Drops 5000 IU Natural Citrus Flavor

Bluebonnet
<p>Strong serving value is paired with 5000 IU of vitamin D. It preserves a disclosed vitamin component but lacks a comparable omega-3 amount, so it is not a like-for-like fatty-acid replacement.</p>
82 Value

High Potency D3 5000 IU

Nature Made
<p>Strong serving value is paired with 5000 IU of vitamin D. It preserves a disclosed vitamin component but lacks a comparable omega-3 amount, so it is not a like-for-like fatty-acid replacement.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  2. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies.
    Chowdhury R; Kunutsor S; Vitezova A; Oliver-Williams C; Chowdhury S; Kiefte-de-Jong JC; Khan H; Baena CP; Prabhakaran D; Hoshen MB; Feldman BS; Pan A; Johnson L; Crowe F; Hu FB; Franco OH · BMJ (Clinical research ed.) · 2014
    Meta-analysis95 studies pooledGeneral Health forVitamin D
  3. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  4. Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis.
    Bournot AR; Darling AL; Givens ID; Lovegrove JA; Lanham-New SA; Hart KH · Public health nutrition · 2024
    Meta-analysis36,707 participants18 studies pooledImmunity forVitamin D
  5. Impact of Vitamin D Supplementation on Influenza Vaccine Response and Immune Functions in Deficient Elderly Persons: A Randomized Placebo-Controlled Trial.
    Goncalves-Mendes N; Talvas J; Dualé C; Guttmann A; Corbin V; Marceau G; Sapin V; Brachet P; Evrard B; Laurichesse H; Vasson MP · Frontiers in immunology · 2019
    Randomized trial38 participantsImmunity forVitamin D
  6. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  7. Could vitamin D reduce obesity-associated inflammation? Observational and Mendelian randomization study.
    Palaniswamy S; Gill D; De Silva NM; Lowry E; Jokelainen J; Karhu T; Mutt SJ; Dehghan A; Sliz E; Chasman DI; Timonen M; Viinamäki H; Keinänen-Kiukaanniemi S; Hyppönen E; Herzig KH; Sebert S; Järvelin MR · The American journal of clinical nutrition · 2020
    Observational study3,586 participantsAnti-Inflammatory Support forVitamin D
  8. Effects of Vitamin D3 and Marine Omega-3 Fatty Acids Supplementation on Biomarkers of Systemic Inflammation: 4-Year Findings from the VITAL Randomized Trial.
    Dong Y; Zhu H; Chen L; Huang Y; Christen W; Cook NR; Copeland T; Mora S; Buring JE; Lee IM; Costenbader KH; Manson JE · Nutrients · 2022
    Randomized trial1,054 participantsAnti-Inflammatory Support forVitamin D
  9. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers.
    Ferguson JF; Mulvey CK; Patel PN; Shah RY; Doveikis J; Zhang W; Tabita-Martinez J; Terembula K; Eiden M; Koulman A; Griffin JL; Mehta NN; Shah R; Propert KJ; Song WL; Reilly MP · Molecular nutrition & food research · 2015
    Randomized trial60 participantsImmunity forOmega-3
  10. Nutritional Support with Omega-3 Fatty Acids in Burn Patients: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.
    Siritientong T; Thet D; Buangbon M; Nokehoon P; Leelakanok N; Methaneethorn J; Angspatt A; Meevassana J · Nutrients · 2022
    Meta-analysis7 studies pooledImmunity forOmega-3
  11. Meta-analysis of omega-3 polyunsaturated fatty acids on immune functions and nutritional status of patients with colorectal cancer.
    Yue T; Xiong K; Deng J; Hu W; Tan T; Li S; Yang T; Xiao T · Frontiers in nutrition · 2022
    Meta-analysis1,613 participants20 studies pooledImmunity forOmega-3
  12. Effects of omega-3 supplementation on glucose and lipid metabolism in patients with gestational diabetes: A meta-analysis of randomized controlled trials.
    Liu W; Gao M; Yang S; Sun C; Bi Y; Li Y; Wang J; Yuan X · Journal of diabetes and its complications · 2023
    Meta-analysis331 participants6 studies pooledMetabolism Boost forOmega-3
  13. Fish oil supplementation and insulin sensitivity: a systematic review and meta-analysis.
    Gao H; Geng T; Huang T; Zhao Q · Lipids in health and disease · 2018
    Meta-analysis672 participants17 studies pooledMetabolism Boost forOmega-3
  14. Dietary fats and prevention of type 2 diabetes.
    Risérus U; Willett WC; Hu FB · Progress in lipid research · 2010
    Narrative reviewMetabolism Boost forOmega-3
  15. Effect of omega-3 fatty acids on the telomere length: A mini meta-analysis of clinical trials.
    Ali S; Scapagnini G; Davinelli S · Biomolecular concepts · 2022
    Meta-analysis337 participants5 studies pooledAnti-Aging forOmega-3
  16. Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults.
    Madison AA; Belury MA; Andridge R; Renna ME; Rosie Shrout M; Malarkey WB; Lin J; Epel ES; Kiecolt-Glaser JK · Molecular psychiatry · 2022
    Randomized trial138 participantsAnti-Aging forOmega-3
  17. Omega-3 Polyunsaturated Fatty Acids and Cognitive Decline in Adults with Non-Dementia or Mild Cognitive Impairment: An Overview of Systematic Reviews.
    Barros MI; Brandão T; Irving SC; Alves P; Gomes F; Correia M · Nutrients · 2025
    Meta-analysis26,881 participants9 studies pooledAnti-Aging forOmega-3
  18. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease.
    Farzaneh-Far R; Lin J; Epel ES; Harris WS; Blackburn EH; Whooley MA · JAMA · 2010
    Cohort study608 participantsAnti-Aging forOmega-3
  19. Long-chain omega-3 fatty acids improve brain function and structure in older adults.
    Witte AV; Kerti L; Hermannstädter HM; Fiebach JB; Schreiber SJ; Schuchardt JP; Hahn A; Flöel A · Cerebral cortex (New York, N.Y. : 1991) · 2015
    Randomized trial65 participantsAnti-Aging forOmega-3
  20. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  21. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  22. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  23. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  24. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  25. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  26. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  27. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  28. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  29. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  30. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  31. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  32. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  33. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  34. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  35. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  36. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  37. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  38. Effects of omega-3 fatty acids on hyper-inflammatory response and clinical outcomes in critically ill patients: a meta-analysis.
    Liu T; Wang X; Wang XH; Wang C; Cai JZ; Wang HF · Intensive & critical care nursing · 2025
    Meta-analysis3,152 participants41 studies pooledImmunity forOmega-3
  39. Effect of ω-3 polyunsaturated fatty acid-supplemented parenteral nutrition on inflammatory and immune function in postoperative patients with gastrointestinal malignancy: A meta-analysis of randomized control trials in China.
    Zhao Y; Wang C · Medicine · 2018
    Meta-analysis1,008 participants16 studies pooledImmunity forOmega-3
  40. Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis.
    Yu J; Liu L; Zhang Y; Wei J; Yang F · BMC cancer · 2017
    Meta-analysis623 participants9 studies pooledImmunity forOmega-3
  41. Omega-3 fatty acid supplementation during pregnancy and respiratory symptoms in children.
    Escamilla-Nuñez MC; Barraza-Villarreal A; Hernández-Cadena L; Navarro-Olivos E; Sly PD; Romieu I · Chest · 2014
    Randomized trial1,094 participantsImmunity forOmega-3
  42. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  43. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  44. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  45. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  46. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis.
    Berbert AA; Kondo CR; Almendra CL; Matsuo T; Dichi I · Nutrition (Burbank, Los Angeles County, Calif.) · 2005
    Randomized trial43 participantsJoint Health forOmega-3
  47. Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial.
    Stonehouse W; Benassi-Evans B; Bednarz J; Vincent AD; Hall S; Hill CL · The American journal of clinical nutrition · 2022
    Randomized trial235 participantsJoint Health forOmega-3
  48. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
    Wang W; Xu Y; Zhou J; Zang Y · Clinical rheumatology · 2024
    Meta-analysis1,018 participants18 studies pooledJoint Health forOmega-3
  49. Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis.
    Sigaux J; Mathieu S; Nguyen Y; Sanchez P; Letarouilly JG; Soubrier M; Czernichow S; Flipo RM; Sellam J; Daïen C · Arthritis research & therapy · 2022
    Meta-analysis1,420 participants30 studies pooledJoint Health forOmega-3
  50. A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
    Goldberg RJ; Katz J · Pain · 2007
    Meta-analysis17 studies pooledJoint Health forOmega-3
  51. Knee effusion-synovitis volume measurement and effects of vitamin D supplementation in patients with knee osteoarthritis.
    Wang X; Cicuttini F; Jin X; Wluka AE; Han W; Zhu Z; Blizzard L; Antony B; Winzenberg T; Jones G; Ding C · Osteoarthritis and cartilage · 2018
    Randomized trial413 participantsJoint Health forVitamin D
  52. Vitamin D Deficiency Leads to Poorer Health Outcomes and Greater Length of Stay After Total Knee Arthroplasty and Supplementation Improves Outcomes: A Systematic Review and Meta-Analysis.
    Vivek K; Kamal R; Perera E; Gupte CM · JBJS reviews · 2024
    Meta-analysis146,054 participants10 studies pooledJoint Health forVitamin D
  53. Does vitamin D improve symptomatic and structural outcomes in knee osteoarthritis? A systematic review and meta-analysis.
    Zhao ZX; He Y; Peng LH; Luo X; Liu M; He CS; Chen J · Aging clinical and experimental research · 2021
    Meta-analysis1,599 participants6 studies pooledJoint Health forVitamin D
  54. Baseline 25-hydroxyvitamin D levels predict the effects of vitamin D supplementation on joint symptoms and cartilage loss in patients with knee osteoarthritis.
    Wang T; Zheng S; Jin X; Cen H; Zhu Z; Han W; Wluka A; Cicuttini F; Cao P; Ding C · Rheumatology advances in practice · 2025
    Randomized trial413 participantsJoint Health forVitamin D
  55. The Efficacy and Safety of Disease-Modifying Osteoarthritis Drugs for Knee and Hip Osteoarthritis-a Systematic Review and Network Meta-Analysis.
    Yang W; Sun C; He SQ; Chen JY; Wang Y; Zhuo Q · Journal of general internal medicine · 2021
    Meta-analysis11,890 participants28 studies pooledJoint Health forVitamin D
  56. Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism.
    Green CJ; Pramfalk C; Charlton CA; Gunn PJ; Cornfield T; Pavlides M; Karpe F; Hodson L · BMJ open diabetes research & care · 2021
    Randomized trial38 participantsMetabolism Boost forOmega-3
  57. Clinical and metabolic response to flaxseed oil omega-3 fatty acids supplementation in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Soleimani Z; Hashemdokht F; Bahmani F; Taghizadeh M; Memarzadeh MR; Asemi Z · Journal of diabetes and its complications · 2018
    Randomized trial60 participantsMetabolism Boost Skin Health forOmega-3
  58. The Effects of Flaxseed Oil Omega-3 Fatty Acids Supplementation on Metabolic Status of Patients with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Mirmasoumi G; Fazilati M; Foroozanfard F; Vahedpoor Z; Mahmoodi S; Taghizadeh M; Esfeh NK; Mohseni M; Karbassizadeh H; Asemi Z · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association · 2018
    Randomized trial60 participantsMetabolism Boost forOmega-3
  59. A combination of omega-3 and plant sterols regulate glucose and lipid metabolism in individuals with impaired glucose regulation: a randomized and controlled clinical trial.
    Wang JF; Zhang HM; Li YY; Xia S; Wei Y; Yang L; Wang D; Ye JJ; Li HX; Yuan J; Pan RR · Lipids in health and disease · 2019
    Randomized trial200 participantsMetabolism Boost forOmega-3
  60. Effects of vitamin D supplementation on insulin resistance and lipid metabolic profiles in women with gestational diabetes mellitus: A randomized controlled trial.
    Duan Y; Zhang S; Ma X; Li L; Jia K · African journal of reproductive health · 2026
    Randomized trial120 participantsMetabolism Boost forVitamin D
  61. Vitamin D3 improves glucose metabolism and attenuates inflammation in prediabetic human and mice.
    Zhang Y; Ni P; Miao Y; Chen H; Tang L; Song H; Li W; Li X · The Journal of nutritional biochemistry · 2024
    Randomized trialMetabolism Boost forVitamin D
  62. Effects of vitamin D and calcium supplementation on pancreatic β cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial.
    Mitri J; Dawson-Hughes B; Hu FB; Pittas AG · The American journal of clinical nutrition · 2011
    Randomized trial92 participantsMetabolism Boost forVitamin D
  63. The Effects of Vitamin D Supplementation on Glycemic Control, Lipid Profiles and C-Reactive Protein Among Patients with Cardiovascular Disease: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Ostadmohammadi V; Milajerdi A; Ghayour-Mobarhan M; Ferns G; Taghizadeh M; Badehnoosh B; Mirzaei H; Asemi Z · Current pharmaceutical design · 2020
    Meta-analysis630 participants8 studies pooledMetabolism Boost forVitamin D
  64. The Effect of Improved Serum 25-Hydroxyvitamin D Status on Glycemic Control in Diabetic Patients: A Meta-Analysis.
    Mirhosseini N; Vatanparast H; Mazidi M; Kimball SM · The Journal of clinical endocrinology and metabolism · 2017
    Meta-analysis1,528 participants24 studies pooledMetabolism Boost forVitamin D
  65. Dietetic intervention in psoriatic arthritis: the DIETA trial.
    Leite BF; Morimoto MA; Gomes CMF; Klemz BNC; Genaro PS; Shivappa N; Hébert JR; Damasceno NRT; Pinheiro MM · Advances in rheumatology (London, England) · 2022
    Randomized trial97 participantsSkin Health forOmega-3
  66. Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
    Miura K; Vail A; Chambers D; Hopkins PM; Ferguson L; Grant M; Rhodes LE; Green AC · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019
    Randomized trial49 participantsSkin Health forOmega-3
  67. Treatment of hard-to-heal wounds in ischaemic lower extremities with a novel fish skin-derived matrix.
    Lee YJ; Han HJ; Shim HS · Journal of wound care · 2024
    Randomized trial50 participantsSkin Health forOmega-3
  68. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.
    Rhodes LE; Shahbakhti H; Azurdia RM; Moison RM; Steenwinkel MJ; Homburg MI; Dean MP; McArdle F; Beijersbergen van Henegouwen GM; Epe B; Vink AA · Carcinogenesis · 2003
    Randomized trial42 participantsSkin Health forOmega-3
  69. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  70. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  71. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  72. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  73. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D