Product Image

Active Metabolism

Bayer One A Day Women's
4.7
★ ★ ★ ★ ★
(354 ratings)
Caffeine 120 mg
Iron 18 mg
Calcium 300 mg
Copper 2 mg
Manganese 2 mg
Chromium 120 mcg
Product Image
Score76
An economical caffeinated multivitamin with broad coverage, but unclear forms and iron-caffeine trade-offs reduce flexibility.
How scoring works
Quantity:50 Tablet(s) • (50 servings)
Goals:
Energy
Metabolism Boost
Productivity Boost
Hair Health
Weight Loss
Mental Focus

Score 76

An economical caffeinated multivitamin with broad coverage, but unclear forms and iron-caffeine trade-offs reduce flexibility.
How scoring works
$10.90($0.21 per serving)
Vitacost
$ 14.29
iHerb
$ 10.90
Report prices

Analysis

The tablet provides a wide vitamin and mineral range with 18 mg of iron and 120 mg of caffeine. It is designed to combine multivitamin coverage with a noticeable immediate alertness effect.

Most chemical forms are not identified, making absorption and digestive tolerance hard to judge. Calcium, zinc, and iron share one tablet and may compete, while chromium is present in a modest amount.

Low serving cost makes it practical for caffeine-tolerant adults who want an all-in-one morning product. It is a poor fit for evenings, pregnancy without clinician review, or anyone who does not need supplemental iron.

Who is it for
  • Caffeine-tolerant adult women
  • Morning multivitamin users
  • People who have a reason for supplemental iron
Best for
  • Morning alertness
  • Broad micronutrient coverage
  • Convenient one-tablet use

Pros

  • Broad vitamin and mineral profile
  • Clearly states caffeine and iron amounts
  • Low serving cost

Cons

  • Most chemical forms are undisclosed
  • Calcium may compete with iron
  • Caffeine reduces timing flexibility

Warnings

  • The 120 mg caffeine amount may cause jitters, rapid heartbeat, or sleep disruption
  • Avoid combining with other high-caffeine products
  • People who do not need iron or who have iron-storage disorders should not use an iron-containing multivitamin without guidance

Nutrient quality

72 High impact

Broad vitamins, minerals, iron, and caffeine provide useful nutritional and alertness support. Missing chemical forms and shallow magnesium and selenium amounts limit ingredient quality and metabolic depth.

Ingredient transparency

75 High impact

Every active has an amount, but most vitamin and mineral chemical forms are not identified. Complete stimulant guidance and tablet excipients are also not supplied.

Customer satisfaction

73 High impact

The very strong average rating has a moderate review base. No review excerpts describe taste, tolerance, ease of use, or repeated complaints, so those experiences remain uncertain.

Value for money

87 Highest impact

A long supply and broad coverage provide strong budget value. Missing form details and limited mineral depth keep quality below more transparent multivitamins.

Report analysis

Goals

Energy
Energy
Impact
Highest effect
A+ Goal FitB Strength of SupportA- CoverageB+ Formula Quality
Vitamin D · 20 mcgVitamin B5 · 5 mgMagnesium · 50 mgRiboflavin · 2.7 mgThiamin · 1.9 mgVitamin B12 · 9 mcgIron · 18 mgCaffeine · 120 mg

Caffeine provides reliable acute alertness, while B vitamins and iron support metabolic fuel use and oxygen transport. The combination covers both immediate and foundational energy pathways.

The stimulant amount is moderate and clearly disclosed, but most vitamin and mineral forms are not identified. Caffeine may cause jitters, faster heart rate, or sleep disruption, while the iron component is most appropriate for people with an actual iron need.

Study evidence
Caffeine Supportive 68 studies
Iron Supportive 74 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
A Goal FitB- Strength of SupportA- CoverageB Formula Quality
Biotin · 30 mcgNiacin · 10 mgVitamin B12 · 9 mcgRiboflavin · 2.7 mgThiamin · 1.9 mgVitamin B5 · 5 mgVitamin B6 · 3.2 mgVitamin D · 20 mcgZinc · 15 mgMagnesium · 50 mgCaffeine · 120 mg

Caffeine provides direct thermogenic support, while B vitamins, chromium, and selenium cover energy and nutrient pathways. Several micronutrients are useful cofactors, but magnesium and chromium are modestly dosed.

The broad formula is coherent for daily nutritional and stimulant support, though many ingredients are not direct metabolism boosters. The 120 mg caffeine amount may cause jitters or sleep disruption in caffeine-sensitive users, especially when taken later in the day.

Study evidence
Caffeine Disputed 40 studies
Chromium Supportive 47 studies
Magnesium Supportive 61 studies
Selenium Mixed 28 studies
Productivity Boost
Productivity Boost
Impact
High effect
B+ Goal FitB Strength of SupportC+ CoverageD Formula Quality
Iron · 18 mgVitamin B12 · 9 mcgVitamin B12 · 9 mcgVitamin B6 · 3.2 mgZinc · 15 mgMagnesium · 50 mgCaffeine · 120 mg

Caffeine provides a clear, evidence-based alertness effect at a moderate amount. Iron and B vitamins may support energy when intake is inadequate.

The broad multivitamin base is not needed for an acute productivity effect and the ingredient forms are incompletely disclosed. Caffeine-sensitive users may experience jitters or sleep disruption, especially when taken later in the day.

Study evidence
Caffeine Supportive 108 studies
Iron Supportive 69 studies
Hair Health
Hair Health
Impact
High effect
C+ Goal FitB- Strength of SupportB- CoverageC Formula Quality
Biotin · 30 mcgVitamin D · 20 mcgZinc · 15 mgIron · 18 mgVitamin C · 60 mg

Iron, zinc, vitamin D, biotin, and copper provide broad nutrient support that may help when dietary gaps contribute to shedding. The multivitamin does not directly target hair structure or follicle signaling.

Most nutrient amounts are meaningful, but several chemical forms are not identified. Added caffeine is unrelated to hair support and may disturb sleep in sensitive users.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Iron Disputed 25 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Weight Loss
Weight Loss
Impact
High effect
B Goal FitB- Strength of SupportC CoverageC- Formula Quality
Vitamin D · 20 mcgMagnesium · 50 mgSelenium · 20 mcgCaffeine · 120 mgZinc · 15 mg

The moderate caffeine amount provides the clearest weight-management contribution by supporting thermogenesis, alertness, and exercise effort. Chromium adds a possible glucose-control pathway, but its amount is modest and the broad vitamin-mineral base mainly supports general nutrition rather than direct fat loss.

Every active amount is listed, yet the chemical forms of caffeine, chromium, and many micronutrients are not identified. The 120 mg caffeine serving may cause jitters or sleep disruption in sensitive users, especially when taken later in the day.

Study evidence
Caffeine Disputed 14 studies
Chromium No effect 24 studies
Mental Focus
Mental Focus
Impact
High effect
B- Goal FitB- Strength of SupportC+ CoverageD+ Formula Quality
Folate · 665 mcg DFEVitamin B6 · 3.2 mgVitamin D · 20 mcgVitamin B12 · 9 mcgMagnesium · 50 mgCaffeine · 120 mg

A moderate caffeine amount provides direct alertness, while B vitamins and iron support energy metabolism when intake is inadequate. The formula may help focus most when tiredness is related to low nutrient status.

Most vitamins and minerals do not add acute cognitive benefit for someone who is already replete, so the multivitamin design is broader than the goal requires. The 18 mg iron amount is inappropriate for some users without a demonstrated need, and 120 mg caffeine may cause jitters or disturb sleep.

Study evidence
Caffeine Supportive 128 studies
Iron Adverse 33 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 750 mcg
Vitamin C
60 mg
Vitamin D
20 mcg
Vitamin E
10.1 mg
Vitamin K
25 mcg
Thiamine (Vitamin B1)
 1.9 mg
Riboflavin (Vitamin B2)
 2.7 mg
Niacin
10 mg
Vitamin B6
3.2 mg
Folate
665 mcg DFE
Vitamin B12
9 mcg
Biotin
30 mcg
Pantothenic Acid
5 mg
Calcium
300 mg
Iron
18 mg
Magnesium
50 mg
Zinc
15 mg
Selenium
20 mcg
Copper
2 mg
Manganese
2 mg
Chromium
120 mcg
Caffeine
120 mg
Women 18–50
Report overview
Caffeine · 120 mg OverallScore69
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The clearly disclosed 120 mg caffeine dose sits in a moderate range that may support alertness with a manageable safety margin for many healthy adults. A plain immediate-release tablet offers no named caffeine source or release technology, so purity and timing features are hard to assess. The low serving cost supports good value, while caffeine-sensitive users may still experience jitters or disrupted sleep if taken late.

View ingredientView products
Iron · 18 mg OverallScore60
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The elemental iron amount fits a common daily target and comes with vitamin C, folate, and vitamin B12. The undisclosed iron form, hard tablet, and competing calcium and zinc limit confidence in absorption and digestive comfort. The serving offers good value, but its caffeine may cause jitters or disturb sleep in sensitive users.

View ingredientView products
Calcium · 300 mg OverallScore59
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

A moderate calcium amount is clearly quantified in the metabolism-focused multivitamin, but its chemical form is not disclosed. The dose can supplement daily intake, although unknown form and elemental context limit absorption confidence. Low serving cost offers strong multivitamin value despite unclear calcium form.

View ingredientView products
Loading alternative details
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Chewable Adult Multi Pineapple-Orange Flavor

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Active B6 and riboflavin, natural vitamin E, and several citrate minerals improve form quality over the original's largely unspecified forms. Very low vitamin D, aggressive vitamin A and E amounts, and no caffeine make the profile uneven and less energizing.
70 Performance

Cal-Mag Caps

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Calcium, magnesium, vitamin D3, and balanced trace minerals provide more focused bone-mineral support with several useful forms. It is not a complete women's multivitamin and offers no caffeine-driven alertness, so it replaces only the mineral side of the original.
55 Performance

Ripped Fuel Extreme

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A stimulant-centered formula may support short-term energy and metabolism more directly than a multivitamin. Overlapping caffeine and cocoa entries obscure total exposure, and the combination may raise the risk of jitteriness, rapid heartbeat, or sleep disruption.
85 Budget

Women's Daily Multi Formula

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A broad women's multivitamin supplies iron, calcium, vitamin D3, and zinc at lower recurring cost without added caffeine. Basic mineral forms and calcium-iron competition are limitations, but it avoids the original's stimulant-related sleep and jitter concerns.
75 Budget

Mini-Multi

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Broad one-daily vitamin coverage and several useful forms come at a lower serving cost. Calcium and magnesium are too small for meaningful support and no caffeine is included, so it favors nutritional maintenance over an immediate energy effect.
80 Budget

Women's Petites

Bayer One A Day Women's
Broad vitamins and minerals with iron provide a lower-cost women's alternative in smaller tablets. Chemical forms are mostly missing and calcium may reduce iron absorption, but the formula avoids the original's substantial caffeine exposure.
69 Value

One Daily Men's Health with Lycopene

21st Century
Broad vitamin and mineral coverage offers strong nutritional value without a stimulant. It is marketed for men and uses several basic forms, so women needing iron or sex-specific coverage should choose a closer formula.
73 Value

Calcium Citrate Caps

NOW
Calcium citrate and chelated trace minerals provide focused bone-mineral value with clearer forms than the original. Magnesium oxide and vitamin D2 weaken the formula, and it does not replace the original's broad vitamins, iron, or caffeine.
68 Value

Caltrate Bone Health Advanced 600+D3

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Calcium, vitamin D3, and supportive trace minerals provide economical bone support. Missing chemical forms and the absence of broad vitamins, iron, and caffeine make it a narrow alternative rather than a metabolism multivitamin.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Using coffee to compensate for poor sleep: Impact on vigilance and implications for workplace performance.
    Anderson JR; Hagerdorn PL; Gunstad J; Spitznagel MB · Applied ergonomics · 2018
    Randomized trial69 participantsMental Focus forCaffeine
  2. Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.
    Paech GM; Banks S; Pajcin M; Grant C; Johnson K; Kamimori GH; Vedova CB · Pharmacology, biochemistry, and behavior · 2017
    Randomized trial24 participantsEnergy forCaffeine
  3. No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
    Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial56 participantsEnergy forCaffeine
  4. Physiological and cognitive responses to caffeine during repeated, high-intensity exercise.
    Crowe MJ; Leicht AS; Spinks WL · International journal of sport nutrition and exercise metabolism · 2007
    Randomized trial17 participantsMental Focus forCaffeine
  5. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
    Juliano LM; Griffiths RR · Psychopharmacology · 2005
    Systematic review66 studies pooledEnergy forCaffeine
  6. Caffeinated Coffee and Tea Consumption, Genetic Variation and Cognitive Function in the UK Biobank.
    Cornelis MC; Weintraub S; Morris MC · The Journal of nutrition · 2020
    Cross-sectional study445,786 participantsMental Focus forCaffeine
  7. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  8. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  9. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  10. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  11. The effects of L-theanine, caffeine and their combination on cognition and mood.
    Haskell CF; Kennedy DO; Milne AL; Wesnes KA; Scholey AB · Biological psychology · 2008
    Randomized trialMental Focus forCaffeine
  12. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  13. Caffeine and attentional control: improved and impaired performance in healthy older adults and Parkinson's disease according to task demands.
    Sharma K; Fallon SJ; Davis T; Ankrett S; Munro G; Christopher G; Coulthard E · Psychopharmacology · 2022
    Randomized trial68 participantsMental Focus forCaffeine
  14. Effect of Caffeine on Golf Performance and Fatigue during a Competitive Tournament.
    Mumford PW; Tribby AC; Poole CN; Dalbo VJ; Scanlan AT; Moon JR; Roberts MD; Young KC · Medicine and science in sports and exercise · 2016
    Randomized trial12 participantsEnergy forCaffeine
  15. The combined effects of L-theanine and caffeine on cognitive performance and mood.
    Owen GN; Parnell H; De Bruin EA; Rycroft JA · Nutritional neuroscience · 2009
    Randomized trial27 participantsMental Focus forCaffeine
  16. Effects of Caffeine Intake on Cognitive Performance Related to Total Sleep Deprivation and Time on Task: A Randomized Cross-Over Double-Blind Study.
    Quiquempoix M; Sauvet F; Erblang M; Van Beers P; Guillard M; Drogou C; Trignol A; Vergez A; Léger D; Chennaoui M; Gomez-Merino D; Rabat A · Nature and science of sleep · 2022
    Randomized trial24 participantsEnergy forCaffeine
  17. The effect of mouth rinsing with different concentrations of caffeine solutions on reaction time.
    Virdinli SG; Kutlay E; Yuzbasioglu Y; Vollaard NBJ; Rudarli Nalcakan G · Journal of sports sciences · 2022
    Randomized trial45 participantsMental Focus forCaffeine
  18. Caffeine Supplementation and Physical Performance, Muscle Damage and Perception of Fatigue in Soccer Players: A Systematic Review.
    Mielgo-Ayuso J; Calleja-Gonzalez J; Del Coso J; Urdampilleta A; León-Guereño P; Fernández-Lázaro D · Nutrients · 2019
    Systematic review17 participants17 studies pooledEnergy forCaffeine
  19. Caffeine attenuates scopolamine-induced memory impairment in humans.
    Riedel W; Hogervorst E; Leboux R; Verhey F; van Praag H; Jolles J · Psychopharmacology · 1996
    Randomized trial16 participantsMental Focus forCaffeine
  20. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsEnergy Metabolism Boost forCaffeine
  21. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  22. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  23. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  24. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  25. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  26. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  27. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  28. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  29. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  30. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  31. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  32. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  33. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  34. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  35. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  36. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  37. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  38. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  39. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  40. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  41. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  42. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  43. Large-dose intravenous ferric carboxymaltose injection for iron deficiency anemia in heavy uterine bleeding: a randomized, controlled trial.
    Van Wyck DB; Mangione A; Morrison J; Hadley PE; Jehle JA; Goodnough LT · Transfusion · 2010
    Randomized trial477 participantsEnergy forIron
  44. The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT.
    Macher S; Herster C; Holter M; Moritz M; Matzhold EM; Stojakovic T; Pieber TR; Schlenke P; Drexler C; Amrein K · Nutrients · 2021
    Randomized trial176 participantsEnergy forIron
  45. Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP).
    Breymann C; Milman N; Mezzacasa A; Bernard R; Dudenhausen J; FER-ASAP investigators · Journal of perinatal medicine · 2018
    Randomized trial252 participantsEnergy forIron
  46. Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial.
    Sultana N; Bajwa FA; Sikandar MZ; Haider MM; Majeed T · JPMA. The Journal of the Pakistan Medical Association · 2026
    Randomized trial164 participantsEnergy forIron
  47. Intravenous iron isomaltoside treatment of women suffering from severe fatigue after postpartum hemorrhage.
    Holm C; Thomsen LL; Langhoff-Roos J · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
    Randomized trial85 participantsEnergy forIron
  48. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  49. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  50. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  51. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  52. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  53. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  54. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  55. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  56. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
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