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CoQ10 & BioPQQ with Shilajit

Global Healing Center
4.8
★ ★ ★ ★ ★
(96 ratings)
Coenzyme Q-10 150 mg
Shilajit 85 mg
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Score80
A well-disclosed, high-quality mitochondrial stack whose main trade-offs are dry-capsule delivery and premium cost.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Energy
Heart Health
Metabolism Boost
Cardiovascular Support
Anti-Aging
Anti-Inflammatory Support

Score 80

A well-disclosed, high-quality mitochondrial stack whose main trade-offs are dry-capsule delivery and premium cost.
How scoring works
$69.95($1.16 per serving)
Vitacost
$ 75.27
iHerb
$ 69.95
Pure Formulas
$ 69.95
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Analysis

Kaneka ubiquinol is supplied at 150 mg, a substantial amount in a well-identified active form. BioPQQ and purified shilajit add complementary support for mitochondrial function and sustained cellular energy.

Source transparency is a major strength because both ubiquinol and shilajit use named forms. The formula is concise and avoids a long blend of marginal extras.

A dry capsule does not provide the lipid delivery that can help a fat-soluble ingredient. The high-end ingredient choices also make it better suited to users who value form quality over low cost.

Who is it for
  • Adults seeking stimulant-free cellular-energy support
  • People who want a premium ubiquinol form
  • Users interested in focused mitochondrial support
Best for
  • Sustained energy support
  • Cardiac cellular-energy support
  • A concise CoQ10, PQQ, and shilajit stack

Pros

  • Branded Kaneka ubiquinol
  • Clearly stated amounts for all three actives
  • Purified branded shilajit

Cons

  • No stated lipid carrier
  • Premium serving cost
  • Narrow pathway coverage beyond mitochondrial support

Warnings

  • CoQ10 may reduce warfarin's anticoagulant effect
  • PQQ or shilajit may cause digestive upset in sensitive users
  • Monitor tolerance if using blood-pressure-lowering medicines

Nutrient quality

94 Highest impact

Kaneka ubiquinol, BioPQQ, and PrimaVie shilajit provide excellent form and source quality. Ubiquinol is substantial, while PQQ and shilajit provide purposeful complementary amounts.

Ingredient transparency

81 Highest impact

Every listed active has a specific amount. The provided facts omit a complete capsule or softgel excipient list.

Customer satisfaction

65 High impact

The supplied aggregate rating is very strong. No specific review comments are provided to assess whether negative complaints repeat.

Value for money

78 High impact

Premium branded forms and meaningful doses justify much of the formula quality. The recurring cost is high, partly supported by the premium ubiquinol and cofactors.

Report analysis

Goals

Energy
Impact
Highest effect
A+ Goal FitA Strength of SupportB+ CoverageA Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports mitochondrial electron transport and is supplied at a substantial amount. Branded PQQ and purified shilajit add complementary mitochondrial and resilience support.

The capsule lacks a lipid carrier, but the CoQ10 form and exact amounts remain strong disclosure features. The streamlined three-ingredient design is well aligned with sustained cellular energy rather than acute stimulation.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Heart Health
Impact
Highest effect
A Goal FitA Strength of SupportB CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Kaneka ubiquinol provides a therapeutic CoQ10 amount for cardiac cellular energy. PQQ and purified shilajit add complementary mitochondrial and antioxidant support.

The dry capsule lacks a lipid delivery system for the fat-soluble ubiquinol. The focused formula does not address lipids, nitric oxide, or homocysteine pathways.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Metabolism Boost
Impact
Highest effect
A- Goal FitA Strength of SupportB+ CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol, PQQ, and purified shilajit form a focused mitochondrial-energy combination. The substantial CoQ10 amount gives the product strong depth for cellular energy rather than stimulant-driven thermogenesis.

Branded Kaneka ubiquinol and PrimaVie shilajit provide excellent source and form disclosure. Human evidence is strongest for CoQ10, while PQQ and shilajit have smaller and less conclusive clinical evidence bases.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Cardiovascular Support
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA Formula Quality
Coenzyme Q-10 · 150 mg

Branded ubiquinol provides direct support for cardiac cellular energy in a well-defined active form. Its amount is substantial, and CoQ10 has useful human evidence in selected cardiovascular settings.

PQQ and purified shilajit create a coherent mitochondrial-support combination. The dry capsule lacks a stated lipid carrier, and the formula remains focused on cellular energy rather than broad cardiovascular coverage.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Anti-Aging
Impact
Highest effect
A- Goal FitA- Strength of SupportC+ CoverageA Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol, PQQ, and purified shilajit form a targeted mitochondrial-support stack. The formula strongly fits age-related energy support but covers few nonmitochondrial aging pathways.

Branded Kaneka ubiquinol and a therapeutic amount provide good quality and dose confidence. The dry capsule lacks a lipid carrier, which may reduce the delivery advantage of the premium form.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Anti-Inflammatory Support
Impact
Highest effect
B- Goal FitA- Strength of SupportB- CoverageA Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol, PQQ, and purified shilajit provide a coherent mitochondrial and antioxidant combination. The CoQ10 amount and premium form are particular strengths.

Anti-inflammatory support is indirect rather than centered on COX, LOX, or NF-kB inhibition. Even so, meaningful dosing and high-quality branded ingredients give the formula good depth for oxidative-stress control.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Coenzyme Q10 (Kaneka Q10 Ubiquinol)
150 mg
organic Shilajit (PrimaVie organic purified Shilajit)
85 mg
BioPQQ (Pyrroloquinoline Quinone Disodium Salt)
10 mg
Gluten Free Adults 18–50 Vegan Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

Branded Kaneka ubiquinol provides a well-identified active form at a therapeutic amount. The dry capsule lacks a lipid delivery system, although PQQ and purified shilajit add complementary cofactors. A high serving cost is partly justified by the premium form and added actives.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost Heart Health forCoenzyme Q-10
  2. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  3. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsMetabolism Boost Anti-Aging forCoenzyme Q-10
  4. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  5. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  6. Coenzyme Q10 supplementation increases blood concentrations but shows limited and inconsistent effects on exercise performance: a systematic review and meta-analysis.
    Deng H; Song T; Yin M; Xu K; Zhong Y; Mohd NB; Naharudin MNB; Yusof A; Fan X · The British journal of nutrition · 2026
    Meta-analysis24 studies pooledEnergy forCoenzyme Q-10
  7. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  8. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  9. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  10. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  11. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  12. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  13. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  14. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  15. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  16. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  17. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  18. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  19. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  20. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  21. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  22. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  23. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  24. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  25. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  26. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  27. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  28. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  29. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  30. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  31. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10