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Ubiquinol

Dr. Mercola
4.7
★ ★ ★ ★ ★
(523 ratings)
Coenzyme Q-10 100 mg
Product Image
Score78
A clearly labeled 100 mg ubiquinol capsule with a useful amount. Dry delivery and premium cost reduce its practical edge.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
Heart Health
Cardiovascular Support
Energy
Anti-Aging
Anti-Inflammatory Support
Metabolism Boost

Score 78

A clearly labeled 100 mg ubiquinol capsule with a useful amount. Dry delivery and premium cost reduce its practical edge.
How scoring works

Also available as

5 options
90 servings Coenzyme Q-10 100 mg • 90 Capsule(s) • 90 servings $68.07 ($0.75 per serving) 150.00mg • 90 Capsule(s) servings Coenzyme Q-10 150 mg • 90 Capsule(s) • 90 servings $87.99 ($0.97 per serving) 150.00mg • 30 Capsule(s) servings Coenzyme Q-10 150 mg • 30 Capsule(s) • 30 servings $32.99 ($1.09 per serving) 200.00mg • 90 Capsule(s) servings Coenzyme Q-10 200 mg • 90 Capsule(s) • 90 servings $114.39 ($1.27 per serving) 200.00mg • 30 Capsule(s) servings Coenzyme Q-10 200 mg • 30 Capsule(s) • 30 servings $43.99 ($1.46 per serving)
$23.43($0.78 per serving)
iHerb
$ 25.78
Pure Formulas
$ 23.43
Vitacost
$ 29.29
Report prices

Analysis

One hundred milligrams of ubiquinol provides the reduced CoQ10 form at a practical maintenance amount. Molecular-form disclosure is a meaningful quality strength.

The dry capsule does not list a lipid carrier or separate absorption enhancer. That delivery choice underuses ubiquinol’s potential compared with a well-formulated softgel.

The product may fit users who strongly prefer capsules and want a clearly named active form. Buyers without that preference can find more economical, lipid-compatible ubiquinol options.

Who is it for
  • Adults seeking reduced ubiquinol
  • Users who prefer capsules to softgels
  • People prioritizing molecular-form disclosure
Best for
  • Ubiquinol maintenance in capsule form
  • Routine mitochondrial support
  • Users avoiding softgels

Pros

  • Uses reduced ubiquinol
  • Useful 100 mg amount
  • Clear molecular-form disclosure
  • One-capsule serving

Cons

  • Dry capsule lacks a lipid carrier
  • No absorption enhancer is disclosed
  • Recurring cost is relatively high
  • Less compelling than lipid-compatible alternatives

Warnings

  • Ubiquinol may reduce the anticoagulant effect of warfarin; prescriber monitoring may be needed
  • CoQ10 may add to blood-pressure-lowering medicines and contribute to dizziness in sensitive users
  • Take the dry capsule with a meal containing fat to better support absorption

Nutrient quality

91 Highest impact

Ubiquinol is a preferred form, but the dry capsule has no disclosed lipid carrier. The 100 mg ubiquinol serving is meaningful for routine use.

Ingredient transparency

85 Highest impact

Active amounts are disclosed and no proprietary blend hides them. Daily directions and the complete inactive-ingredient list are not supplied.

Customer satisfaction

67 High impact

The supplied average is strong and the review pool is substantial. No specific feedback is provided to judge recurring complaints or purpose fit.

Value for money

64 Moderate impact

The preferred molecular form supports formula quality. Dry delivery and a high serving cost weaken category competitiveness.

Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports energy production in heart muscle and antioxidant protection. The 100 mg amount is meaningful, and the reduced form offers strong absorption potential.

The focused capsule gives excellent depth for cardiac cellular energy but does not address lipids, vascular tone, or homocysteine. Ubiquinol may reduce warfarin's anticoagulant effect, so clotting control should be monitored when starting or stopping it.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy production in heart muscle and offers relevant antioxidant activity. Human evidence is useful in selected cardiovascular settings, although it does not replace broader risk management.

The 100 mg amount is well supported and the reduced ubiquinol form generally absorbs better than ubiquinone. The dry capsule lacks a disclosed lipid carrier, which may limit uptake of this fat-soluble ingredient.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Energy
Energy
Impact
Highest effect
A- Goal FitA- Strength of SupportD+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial electron transport and ATP production at a well-used 100 mg amount. The reduced form is favorable, but a dry capsule without a disclosed lipid carrier may limit absorption.

The formula provides strong depth in one cellular-energy pathway rather than broad support for alertness or stress. Its single-active design is focused and avoids unnecessary additions.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA- Strength of SupportD+ CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy and is generally easier to absorb than ubiquinone. The amount is meaningful, though the dry capsule has no stated lipid carrier.

The clean single-active formula provides depth without broad aging-pathway coverage. Taking it with a fat-containing meal may be practical because the listed delivery system does not otherwise support this fat-soluble active.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B Goal FitA Strength of SupportC- CoverageA- Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol provides a meaningful CoQ10 dose in a reduced form with strong absorption potential. Its antioxidant and mitochondrial roles may support control of oxidative stress and related inflammatory signaling.

The formula is highly focused and clearly disclosed. It offers strong depth for CoQ10 but does not cover the direct fatty-acid or botanical pathways that would broaden goal support.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B Goal FitA Strength of SupportC- CoverageA Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 supports mitochondrial electron transport, a central step in cellular energy production. The disclosed amount provides useful depth, although evidence for raising whole-body metabolic rate is less direct.

The single-active design is transparent and free from label padding. Coverage remains narrow because thermogenesis, glycemic control, thyroid support, and fatty-acid transport are not addressed.

Study evidence
Coenzyme Q-10 Disputed 11 studies

Ingredients

IngredientAmount per serving
Ubiquinol
100 mg
Adults 18–50
Report overview
Coenzyme Q-10 · 100 mg OverallScore77
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD- Value

Ubiquinol provides the better-absorbed CoQ10 form at a well-supported amount in one capsule. The dry capsule lacks a disclosed lipid carrier or absorption enhancer, which may limit uptake. Its serving cost is high for the amount provided.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
Reduced ubiquinol at 200 mg in a softgel combines a readily absorbed form with a substantial amount for targeted use. Compared with the original, it raises the listed CoQ10 amount from 100 mg to 200 mg and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
85 Performance

Mega Ubiquinol CoQ10 100 mg

Qunol
Reduced ubiquinol at 100 mg in a softgel provides a clearly stated maintenance amount, while the small fat-soluble vitamin C addition contributes limited extra value. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
87 Performance

QH-absorb 100 mg

Jarrow Formulas
Reduced ubiquinol at 100 mg provides a clearly stated maintenance amount, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and retains the original's reduced ubiquinol form, giving a well-specified option for the same CoQ10 goals.
86 Budget

CoQ10 100 mg

Lake Avenue Nutrition
A clearly identified 100 mg ubiquinone amount offers focused CoQ10 support, though the dry capsule lacks a listed lipid carrier. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
85 Budget

High Absorption CoQ10 with BioPerine 100 mg

Doctor's Best
A 100 mg ubiquinone amount with 5 mg of piperine targets absorption, but the dry capsule lacks a lipid carrier and piperine may alter the handling of some medicines. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
84 Budget

CoQ10 100 mg

California Gold Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake of the fat-soluble active, while CoQ10 may reduce warfarin's anticoagulant effect. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while lowering recurring cost.
84 Value

CoQ10 100 mg

Best Naturals
A 100 mg ubiquinone amount provides focused CoQ10 support, though the dry capsule has no stated lipid carrier and CoQ10 may reduce warfarin response. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
83 Value

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
A 100 mg ubiquinone amount in a softgel supports uptake, while 5 mg of black pepper extract may change exposure to some medicines. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
82 Value

CoQ10 100 mg wtih BioPerine

California Gold Nutrition
A 100 mg ubiquinone amount with 5 mg of piperine offers a focused formula, but the dry capsule lacks a lipid carrier and piperine may alter medicine exposure. Compared with the original, it closely matches the original's listed 100 mg CoQ10 amount and uses conventional ubiquinone instead of the original's reduced form, while the lower recurring cost strengthens practical value.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  3. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  4. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  5. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  6. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  7. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  8. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  9. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  10. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  12. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  13. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  14. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  15. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  16. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  17. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  18. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  19. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  20. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  21. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  22. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  23. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  24. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  25. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  26. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  27. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  28. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10