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Ubiquinol 150 mg

Dr. Mercola
4.7
★ ★ ★ ★ ★
(341 ratings)
Coenzyme Q-10 150 mg
Product Image
Score78
A substantial ubiquinol amount gives this capsule strong targeted depth, but its delivery system is not explained. It suits users willing to pay more for the reduced CoQ10 form.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
Heart Health
Energy
Anti-Aging
Cardiovascular Support
Metabolism Boost
Anti-Inflammatory Support

Score 78

A substantial ubiquinol amount gives this capsule strong targeted depth, but its delivery system is not explained. It suits users willing to pay more for the reduced CoQ10 form.
How scoring works

Also available as

5 options
100.00mg • 90 Capsule(s) servings Coenzyme Q-10 100 mg • 90 Capsule(s) • 90 servings $68.07 ($0.75 per serving) 100.00mg • 30 Capsule(s) servings Coenzyme Q-10 100 mg • 30 Capsule(s) • 30 servings $23.43 ($0.78 per serving) 30 servings Coenzyme Q-10 150 mg • 30 Capsule(s) • 30 servings $32.99 ($1.09 per serving) 200.00mg • 90 Capsule(s) servings Coenzyme Q-10 200 mg • 90 Capsule(s) • 90 servings $114.39 ($1.27 per serving) 200.00mg • 30 Capsule(s) servings Coenzyme Q-10 200 mg • 30 Capsule(s) • 30 servings $43.99 ($1.46 per serving)
$87.99($0.97 per serving)
iHerb
$ 87.99
Vitacost
$ 88.99
Report prices

Analysis

The 150 mg ubiquinol serving offers a meaningful amount of the reduced CoQ10 form, which is especially relevant for older adults and people seeking targeted heart or cellular-energy support. Its role is focused on mitochondrial energy production and antioxidant protection rather than broad metabolic coverage.

A single-capsule serving keeps the formula simple and the active amount easy to understand. No oil carrier or other absorption aid is disclosed, so taking it with a meal containing fat is a practical consideration.

The formula fits users who value ubiquinol and do not need a multi-ingredient product, but the serving value is limited compared with many conventional CoQ10 options. CoQ10 can reduce warfarin response, so people using that anticoagulant need coordinated monitoring when starting or stopping it.

Who is it for
  • Older adults seeking a reduced CoQ10 form
  • People wanting focused heart and cellular-energy support
  • Users who prefer a one-capsule formula
Best for
  • Ubiquinol-focused supplementation
  • Mitochondrial energy support
  • Targeted cardiovascular support

Pros

  • Uses the reduced ubiquinol form
  • Substantial active amount per capsule
  • Simple single-active formula

Cons

  • No lipid carrier or absorption enhancer is disclosed
  • Higher serving cost limits value
  • Does not cover other cardiovascular or metabolic pathways

Warnings

  • CoQ10 may reduce warfarin response; anticoagulation monitoring may need adjustment when use starts or stops.

Nutrient quality

93 Highest impact

Ubiquinol is the readily used reduced CoQ10 form, although no lipid carrier is identified. The amount is substantial for targeted CoQ10 support.

Ingredient transparency

82 Highest impact

Specific amounts are disclosed for every listed active ingredient. Non-active ingredients and delivery excipients are not provided.

Customer satisfaction

69 High impact

The supplied average rating is very strong. The substantial rating sample provides good statistical confidence.

Value for money

64 Moderate impact

The preferred reduced form supports premium quality, though delivery lacks an evident lipid carrier. The high serving cost limits value despite the strong form and amount.

Report analysis

Goals

Heart Health
Heart Health
Impact
Highest effect
A Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports energy production and antioxidant protection in high-demand heart tissue. The reduced CoQ10 form and substantial amount are well suited to targeted cardiovascular use.

No lipid carrier or absorption enhancer is disclosed, so delivery may depend on taking the capsule with food containing fat. The focused formula does not address blood pressure, lipids, or vascular calcification.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Energy
Energy
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol supplies a substantial amount of readily used CoQ10 for mitochondrial energy production. The single-capsule formula is transparent and stimulant free.

No lipid carrier or absorption enhancer is disclosed, which may limit uptake compared with a fat-based softgel. Coverage remains focused on one cellular-energy pathway rather than broader alertness or stress support.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports mitochondrial energy and antioxidant protection relevant to healthy aging. The 150 mg amount provides strong targeted depth in the preferred reduced form.

The capsule does not identify a lipid carrier or absorption enhancer. Its focused design leaves structural and inflammatory aging pathways outside the formula.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol directly supports heart-muscle energy and provides a well-supported cardiovascular active. The disclosed amount is meaningful, but the standard capsule lists no oil carrier or other absorption aid.

The formula offers excellent depth for mitochondrial energy and antioxidant support. Its narrow scope leaves lipids, vascular tone, and rhythm unaddressed, yet the single-ingredient design remains clear and efficient.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

A strong ubiquinol amount provides focused support for mitochondrial energy production. It does not add thermogenic, thyroid, or glycemic pathways.

The formula supports cellular energy more directly than calorie expenditure. Benefits may be more noticeable in users with elevated CoQ10 needs.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageA+ Formula Quality
Coenzyme Q-10 · 150 mg

Ubiquinol supplies a favorable CoQ10 form at a meaningful amount for mitochondrial and antioxidant support. CoQ10 may help moderate some inflammatory markers by reducing oxidative strain.

The focused formula clearly states its only active ingredient. No lipid carrier or enhanced-delivery system is disclosed, which limits confidence in absorption support.

Study evidence
Coenzyme Q-10 Supportive 46 studies

Ingredients

IngredientAmount per serving
Ubiquinol
150 mg
Adults 18–50
Report overview
Coenzyme Q-10 · 150 mg OverallScore70
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Ubiquinol provides the preferred reduced form at a solid therapeutic amount. The one-capsule serving is convenient, but no lipid carrier or absorption enhancer is disclosed. The larger bottle improves cost somewhat, yet value remains limited by a high serving price.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
<p>A substantial ubiquinol amount in a softgel provides reduced-form CoQ10 with absorption-aware delivery. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. The amount may be more than needed for basic maintenance.</p>
81 Performance

Ubiquinol Active CoQ10 200 mg

Natural Factors
<p>A substantial ubiquinol amount with organic flaxseed oil combines the reduced form with a lipid carrier. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. Its routine serving cost is comparatively high.</p>
85 Performance

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg

Life Extension
<p>Ubiquinol and a clearly listed shilajit complex provide focused mitochondrial support in a fat-containing softgel. It preserves the original’s reduced CoQ10 form while offering a strong dose or delivery design. Shilajit adds complexity for people seeking CoQ10 alone.</p>
84 Budget

CoQ10 100 mg

Best Naturals
<p>Clearly identified ubiquinone provides a practical maintenance amount in a very economical serving. It lowers routine cost versus the original. The dry capsule has no stated lipid carrier or absorption enhancer.</p>
83 Budget

CoQ10 100 mg plus BioPerine

Lake Avenue Nutrition
<p>A meaningful ubiquinone amount and softgel delivery provide focused routine support. It lowers routine cost versus the original. Black pepper extract may change exposure to some medicines.</p>
84 Budget

CoQ10 100 mg

California Gold Nutrition
<p>Clearly identified ubiquinone and softgel delivery provide a straightforward maintenance formula. It lowers routine cost versus the original. Complete intake directions and excipient details are not supplied.</p>
87 Value

Mega CoQ10 Ubiquinol 100 mg

Qunol
<p>Ubiquinol in a softgel provides the reduced CoQ10 form at a useful maintenance amount. Its ingredient design and serving economics offer a useful value trade-off versus the original. The small ascorbyl-palmitate addition contributes little to the core purpose.</p>
87 Value

CoQ10 200 mg

California Gold Nutrition
<p>A substantial ubiquinone amount and softgel delivery combine focused dosing with efficient serving value. Its ingredient design and serving economics offer a useful value trade-off versus the original. Full intake directions and excipient details are not supplied.</p>
87 Value

QH-absorb 100 mg

Jarrow Formulas
<p>Ubiquinol in a softgel provides reduced-form CoQ10 at a useful maintenance amount with favorable serving value. Its ingredient design and serving economics offer a useful value trade-off versus the original. The amount is lower than higher-dose targeted formulas.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  2. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer.
    Lesser GJ; Case D; Stark N; Williford S; Giguere J; Garino LA; Naughton MJ; Vitolins MZ; Lively MO; Shaw EG; Wake Forest University Community Clinical Oncology Program Research Base · The journal of supportive oncology · 2013
    Randomized trial236 participantsEnergy forCoenzyme Q-10
  3. Platelet mitochondrial function and endogenous coenzyme Q10 levels are reduced in patients after COVID-19.
    Sumbalova Z; Kucharska J; Palacka P; Rausova Z; Langsjoen PH; Langsjoen AM; Gvozdjakova A · Bratislavske lekarske listy · 2022
    Cross-sectional study25 participantsEnergy forCoenzyme Q-10
  4. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledHeart Health Cardiovascular Support forCoenzyme Q-10
  5. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension.
    Ho MJ; Li EC; Wright JM · The Cochrane database of systematic reviews · 2016
    Meta-analysis50 participants3 studies pooledHeart Health forCoenzyme Q-10
  6. Coenzyme Q10: an independent predictor of mortality in chronic heart failure.
    Molyneux SL; Florkowski CM; George PM; Pilbrow AP; Frampton CM; Lever M; Richards AM · Journal of the American College of Cardiology · 2008
    Cohort study236 participantsHeart Health forCoenzyme Q-10
  7. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  8. Coenzyme Q10 for heart failure.
    Madmani ME; Yusuf Solaiman A; Tamr Agha K; Madmani Y; Shahrour Y; Essali A; Kadro W · The Cochrane database of systematic reviews · 2015
    Systematic review914 participants7 studies pooledCardiovascular Support forCoenzyme Q-10
  9. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost Heart Health forCoenzyme Q-10
  10. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsMetabolism Boost Anti-Aging forCoenzyme Q-10
  11. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  12. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  13. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  14. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  15. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  16. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  17. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  18. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  19. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  20. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  21. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  22. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  23. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  24. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  25. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  26. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  27. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  28. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  29. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  30. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  31. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  32. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  33. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10