Chewable 5-HTP 100 mg Natural Citrus Flavor

Chewable 5-HTP 100 mg Natural Citrus Flavor

NOW4.6 (1,122 ratings)
Format:Tablet Quantity: 90 Tablet(s) · 90 servings
Goals
$14.56 $0.16 per serving
AmazonLowest$14.56Daily Vita$16.20Pure Formulas$16.66iHerb$17.13Vitacost$17.43

About this product

The chewable tablet supplies 100 mg of 5-HTP from Griffonia simplicifolia seed extract. Citrus flavor and chewable delivery may make consistent use easier for people who dislike swallowing capsules.

The active may support mood, stress, or sleep, while weight-management effects remain indirect. Chewable delivery does not broaden the mechanism or show a tolerance advantage from the supplied information.

No extract standardization percentage is listed, and specific serotonin-medication guidance is absent. Convenience is the defining feature rather than a meaningful upgrade in ingredient quality.

Who is it for
  • People who prefer chewable supplements
  • Users seeking standard-strength 5-HTP
Best for
  • Capsule-free dosing
  • Convenient flavored use

Pros

  • Provides 100 mg of 5-HTP
  • Names Griffonia seed extract
  • Chewable format is accessible

Cons

  • No extract standardization
  • No clear release or tolerance advantage
  • Covers only one pathway

Warnings

  • Do not combine 5-HTP with SSRIs, SNRIs, MAO inhibitors, triptans, or other serotonin-raising medicines without medical supervision.
  • 5-HTP may cause nausea, digestive discomfort, drowsiness, or vivid dreams.
  • Avoid alertness-dependent tasks until individual response is known.

Product analysis

82 out of 100
A convenient chewable delivers a standard Griffonia-derived 5-HTP amount. It is easy to take but otherwise offers basic formulation and incomplete safety detail.

AI assessment of the formula, label and price. How scoring works

Nutrient quality87

The named Griffonia seed extract gives the active a clear botanical source, although no standardization percentage is supplied. The 100 mg 5-HTP serving is well aligned with common supplemental use, while the focused design avoids unrelated actives.

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Ingredient transparency84

All supplied active ingredients have specific amounts, and no proprietary blend hides key doses. Serving count is available, but full intake directions, excipients, and a serotonin-medication warning are absent from the supplied label details.

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Customer satisfaction66

The supplied aggregate rating is favorable but not exceptional, and review volume determines how much confidence it deserves. No review text is provided to identify repeated complaints or firsthand experiences tied to the intended uses.

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Value for money88

Cost efficiency per equivalent active amount appears good, with the standard dose shaping practical value. The single-active formula does not use decorative ingredients to justify its cost.

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Format
Tablet
Container
90 Tablet(s)
Per serving
$0.16
Customer rating
4.6 · 1,122 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
Highest effect
A Ingredient FitC- PathwaysA EvidenceA+ Formulation Logic
5-HTP · 100 mg
Study evidence
5-HTP Supportive 9 studies
Sleep Support
Sleep Support
Impact
Moderate effect
A Ingredient FitC PathwaysC- EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 1 study
Weight Loss
Weight Loss
Impact
Moderate effect
B- Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 5 studies
Stress Relief
Stress Relief
Impact
Moderate effect
A Ingredient FitD PathwaysC- EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 18 studies

Ingredients

IngredientAmount per servingScore
5-HTP (Griffonia simplicifolia Seed Extract)
 100 mg 85
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
5-HTP (Griffonia simplicifolia Seed Extract) · 100 mg OverallScore85
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value
Chewable 5-HTP 100 mg identifies Griffonia simplicifolia but gives no standardization percentage. It states the 5-HTP amount and records a specific SSRI interaction warning. The cost per declared amount is moderate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The available facts identify Griffonia simplicifolia, but don't state a standardization percentage.
Botanical Source & Standardization
Griffonia simplicifolia is identified, but no standardization percentage is given.

Dose, Safety & Label Transparency100

The amount matches the supplied reference, and a specific interaction warning is recorded.
Dosage Potency & Range
Each serving provides 100 mg, matching the supplied collection reference.
Safety Warnings & Label Clarity
A warning about use with SSRIs or similar medicines is recorded.

Value85

The cost per declared amount is moderate.
Price per 100mg 5-HTP
The cost per declared 100 mg is moderate.
View ingredientView products
Loading alternative details
85 Performance

5-HTP 100 mg

NOW
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP 100 mg Extra Strength

Swanson
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
84 Budget

5-HTP 50 mg

NOW
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving offers a more cautious starting option than the original’s 100 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
85 Budget

5-HTP 100 mg

Doctor's Best
The lower recurring cost makes this a more economical eligible choice. Its 100 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
82 Budget

5-HTP 50 mg

Swanson Premium Brand
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving offers a more cautious starting option than the original’s 100 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP 200mg

Best Naturals
Focused 5-HTP dosing and a lower recurring cost create a favorable quality-to-cost balance. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP with Vitamin B6 & Vitamin C

Lake Avenue Nutrition
Focused 5-HTP dosing and strong formula value make this a practical value alternative. The active amount is disclosed, but botanical-source detail remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
82 Value

5-HTP 200 mg Maximum Strength

Swanson
Focused 5-HTP dosing and strong formula value make this a practical value alternative. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
    Sutanto CN; Xia X; Heng CW; Tan YS; Lee DPS; Fam J; Kim JE · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trial30 participantsSleep Support for5-HTP
  2. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
    Kahn RS; Westenberg HG; Verhoeven WM; Gispen-de Wied CC; Kamerbeek WD · International clinical psychopharmacology · 1987
    Randomized trial45 participantsStress Relief for5-HTP
  3. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
    Schruers K; van Diest R; Overbeek T; Griez E · Psychiatry research · 2003
    Randomized trial48 participantsStress Relief for5-HTP
  4. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
    Emanuele E; Bertona M; Minoretti P; Geroldi D · Neuro endocrinology letters · 2011
    Single-arm trial15 participantsStress Relief for5-HTP
  5. Sex-linked differences in cortisol, ACTH and prolactin responses to 5-hydroxy-tryptophan in healthy controls and minor and major depressed patients.
    Maes M; Vandewoude M; Schotte C; Maes L; Martin M; Blockx P · Acta psychiatrica Scandinavica · 1990
    Clinical trial120 participantsStress Relief for5-HTP
  6. Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD).
    Bertolini F; Robertson L; Bisson JI; Meader N; Churchill R; Ostuzzi G; Stein DJ; Williams T; Barbui C · The Cochrane database of systematic reviews · 2022
    Systematic review2,023 participants13 studies pooledStress Relief for5-HTP
  7. Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
    Smarius LJ; Jacobs GE; Hoeberechts-Lefrandt DH; de Kam ML; van der Post JP; de Rijk R; van Pelt J; Schoemaker RC; Zitman FG; van Gerven JM; Gijsman HJ · Journal of psychopharmacology (Oxford, England) · 2008
    Randomized trialStress Relief for5-HTP
  8. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
    Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
    Randomized trial70 participantsMood Support for5-HTP
  9. Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
    Javelle F; Lampit A; Bloch W; Häussermann P; Johnson SL; Zimmer P · Nutrition reviews · 2020
    Meta-analysis13 studies pooledMood Support for5-HTP
  10. The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
    Li S; Sutanto CN; Xia X; Kim JE · Nutrients · 2025
    Randomized trial30 participantsMood Support for5-HTP
  11. Effect of 5-Hydroxytryptophan on Fatigue in Quiescent Inflammatory Bowel Disease: A Randomized Controlled Trial.
    Truyens M; Lobatón T; Ferrante M; Bossuyt P; Vermeire S; Pouillon L; Dewint P; Cremer A; Peeters H; Lambrecht G; Louis E; Rahier JF; Dewit O; Muls V; Holvoet T; Vandermeulen L; Peeters A; Gonzales GB; Bos S; Laukens D; De Vos M · Gastroenterology · 2022
    Randomized trial166 participantsMood Support for5-HTP
  12. Tryptophan and 5-hydroxytryptophan for depression.
    Shaw K; Turner J; Del Mar C · The Cochrane database of systematic reviews · 2002
    Systematic review64 participants2 studies pooledMood Support for5-HTP
  13. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
    Aliño JJ; Gutierrez JL; Iglesias ML · International pharmacopsychiatry · 1976
    Non-randomized trial30 participantsMood Support for5-HTP
  14. Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Jacobs GE; Kamerling IM; de Kam ML; Derijk RH; van Pelt J; Zitman FG; van Gerven JM · Journal of psychopharmacology (Oxford, England) · 2010
    Randomized trialStress Relief for5-HTP
  15. The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT.
    Evans C; Mekhail V; Curtis J; Czartoryski P; Kaminski J; Ellerbroek A; Bustillo E; Jiannine L; Santana JC; Antonio J · Journal of dietary supplements · 2023
    Randomized trial48 participantsWeight Loss for5-HTP
  16. Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients.
    Cangiano C; Laviano A; Del Ben M; Preziosa I; Angelico F; Cascino A; Rossi-Fanelli F · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 1998
    Randomized trial25 participantsWeight Loss for5-HTP
  17. The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects.
    Ceci F; Cangiano C; Cairella M; Cascino A; Del Ben M; Muscaritoli M; Sibilia L; Rossi Fanelli F · Journal of neural transmission · 1989
    Clinical trial19 participantsWeight Loss for5-HTP
  18. Serotonergic drugs : effects on appetite expression and use for the treatment of obesity.
    Halford JC; Harrold JA; Boyland EJ; Lawton CL; Blundell JE · Drugs · 2007
    Narrative reviewWeight Loss for5-HTP
  19. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan.
    Cangiano C; Ceci F; Cascino A; Del Ben M; Laviano A; Muscaritoli M; Antonucci F; Rossi-Fanelli F · The American journal of clinical nutrition · 1992
    Randomized trial20 participantsWeight Loss for5-HTP