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Saw Palmetto Plus

Pure Encapsulations
4.8
★ ★ ★ ★ ★
(29 ratings)
Saw Palmetto 320 mg
Stinging Nettle 400 mg
Product Image
Score73
A substantial oil-based prostate blend with full-dose saw palmetto and nettle, best suited to users willing to buy a large supply.
How scoring works
Quantity:250 Capsule(s) • (125 servings)
Goals:
Hair Health
Anti-Inflammatory Support

Score 73

A substantial oil-based prostate blend with full-dose saw palmetto and nettle, best suited to users willing to buy a large supply.
How scoring works
$178.00($1.42 per serving)
Pure Formulas
$ 178.00
Vitacost
$ 178.00
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Analysis

Saw palmetto provides 320 mg of extract alongside 400 mg nettle, 640 mg pumpkin oil, and 40 mg pygeum. Those amounts create a more substantial prostate formula than blends built around small botanical additions.

The oil content suits saw palmetto's fatty components, and natural vitamin E supports the lipid base. The label names total fatty acids but does not state the standardized percentage, while nettle and pygeum lack concentration details.

The 250-capsule bottle supplies 125 servings, making it appropriate for someone committed to longer use. Upfront cost is high, yet per-serving value is much better than the small-bottle version of the same formula.

Who is it for
  • Adults seeking a substantial prostate botanical blend
  • Longer-term users comfortable with a large bottle
Best for
  • Full-dose saw palmetto and nettle coverage
  • Combining pumpkin oil with prostate botanicals

Pros

  • 320 mg saw palmetto extract
  • 400 mg nettle extract
  • 640 mg pumpkin oil
  • Large 125-serving supply

Cons

  • Fatty-acid percentage is not stated
  • Pygeum standardization is unclear
  • High upfront cost
  • Requires two capsules per serving

Warnings

  • Saw palmetto may add to bleeding tendency with anticoagulant or antiplatelet medicines.
  • Saw palmetto is unsuitable during pregnancy because of its hormone-related activity.
  • Saw palmetto may affect prostate-specific antigen test interpretation; disclose its use before testing.

Nutrient quality

88 Highest impact

Natural vitamin E and oil-based botanical delivery are useful, but several extracts lack full standardization details. Saw palmetto, nettle, and pumpkin seed oil have substantial amounts, with pygeum serving as a smaller support.

Ingredient transparency

77 High impact

Every listed active ingredient has a specific amount. The provided facts omit a complete excipient and capsule or liquid ingredient list.

Customer satisfaction

61 Moderate impact

The supplied aggregate rating is very strong. No specific review comments are provided to assess whether negative complaints repeat.

Value for money

61 Moderate impact

Substantial botanical doses support quality, but incomplete extract characterization weakens the premium positioning. The recurring serving cost is high for incompletely standardized botanicals.

Report analysis

Goals

Hair Health
Hair Health
Impact
Highest effect
B Goal FitA- Strength of SupportC+ CoverageA Formula Quality

Saw palmetto, pumpkin seed oil, nettle, and pygeum form a focused hormone-oriented blend for pattern hair loss. The main extract and companion botanicals reach meaningful amounts for this specific pathway.

Softgel delivery suits the fat-soluble actives, but the label does not state the saw palmetto fatty-acid percentage. The formula does not address nutrient deficiencies or structural building blocks, so its usefulness depends on the cause of shedding.

Study evidence
Saw Palmetto Supportive 5 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
D Goal FitC Strength of SupportD+ CoverageB- Formula Quality
Vitamin E · 13 mg

Saw palmetto, nettle, pygeum, pumpkin oil, and vitamin E provide some localized inflammatory and antioxidant relevance. The combination is designed for prostate support rather than broad systemic inflammation.

Botanical amounts are substantial, but active-marker and extraction details are incomplete. The formula is coherent for its intended pathway but lacks a direct, well-characterized anti-inflammatory active.

Study evidence
Stinging Nettle Supportive 5 studies
Vitamin E Supportive 20 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Fat
2 Gram(s)
Vitamin E (D-Alpha-Tocopherol)
 13 mg
Saw Palmetto (Serenoa repens) extract (total Fatty Acids)
 320 mg
Pumpkin (Cucurbita pepo) Oil
640 mg
Pygeum (Pygeum africanum) extract
40 mg
Nettle (Urtica dioica) extract
400 mg
Gluten Free Adults 18–50
Report overview
Saw Palmetto (total Fatty Acids) · 320 mg OverallScore58
D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value

Total fatty acids are named without a standardization percentage. The 320 mg daily amount matches the clinical target. Softgel delivery with pumpkin seed oil supports absorption of fat-soluble actives; the high serving cost is partly offset by full-dose pumpkin seed oil and nettle plus pygeum.

View ingredientView products
Stinging Nettle · 400 mg OverallScore54
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

A substantial nettle extract amount is combined with saw palmetto and pygeum in a prostate-focused formula. The label does not identify nettle root or provide concentration details, leaving an important quality gap. Very high serving cost makes that incomplete disclosure difficult to accept.

View ingredientView products
Loading alternative details
80 Performance

Prostate Support

NOW
<p>Nettle, pumpkin seed oil, saw palmetto, zinc, and lycopene form a coherent prostate-support formula. Its matching ingredient coverage stays close to the original’s intended uses while offering a clearer or more focused formulation. Extensive customer evidence and favorable serving economics support good practical value.</p>
78 Performance

Herbal Prostate Complex

Swanson
<p>Large disclosed amounts of saw palmetto and pygeum pair with a concentrated nettle root extract in a focused prostate formula. Its matching ingredient coverage stays close to the original’s intended uses while offering a clearer or more focused formulation. Saw palmetto and nettle may interact with hormone-related therapies or blood-thinning medicines.</p>
76 Performance

Ortho Prostate

Protocol For Life Balance
<p>The prostate-focused blend combines useful zinc, nettle root, pumpkin seed oil, and oil-compatible botanicals, but saw palmetto and lycopene are modest and incompletely standardized. Its matching ingredient coverage stays close to the original’s intended uses while offering a clearer or more focused formulation. Label transparency is generally good, customer ratings are strong, and the formula offers fair rather than standout value.</p>
84 Budget

Stinging Nettles

Swanson Superior Herbs
<p>Separate leaf and root extracts provide unusually clear plant-part disclosure, and the leaf includes a named marker. Its lower serving cost makes it a more economical choice than the original while retaining relevant Saw Palmetto and Stinging Nettle support. Strong customer sentiment and exceptionally economical servings support excellent value.</p>
83 Budget

Stinging Nettle Root Extract 250 mg

NOW
<p>A substantial nettle root extract amount supports focused botanical use. Its lower serving cost makes it a more economical choice than the original while retaining relevant Saw Palmetto and Stinging Nettle support. Extensive positive customer sentiment and economical servings create strong value.</p>
83 Budget

Nettle Root 250 mg

California Gold Nutrition EuroHerbs
<p>Two identified nettle root species provide a substantial focused serving. Its lower serving cost makes it a more economical choice than the original while retaining relevant Saw Palmetto and Stinging Nettle support. Missing concentration ratios and active-marker standardization limit potency precision, but the long supply offers excellent value.</p>
81 Value

Stinging Nettle Root 500 mg

Swanson
<p>A substantial nettle root amount provides clear, focused raw-herb value. Its disclosed ingredients and stronger recurring value provide a better quality-to-cost balance for Saw Palmetto and Stinging Nettle. Extensive favorable customer sentiment and exceptionally economical servings support a strong practical choice.</p>
80 Value

Stinging Nettles 480 mg

The Vitamin Shoppe
<p>A substantial nettle extract amount and economical servings create appealing basic value. Its disclosed ingredients and stronger recurring value provide a better quality-to-cost balance for Saw Palmetto and Stinging Nettle. Favorable customer sentiment supports the practical case.</p>
76 Value

Saw Palmetto Extract 160 mg

NOW
<p>The oil-friendly softgel is a sensible delivery choice, but the extract amount is below a common full daily target. Its disclosed ingredients and stronger recurring value provide a better quality-to-cost balance for Saw Palmetto and Stinging Nettle. Saw palmetto has hormone-related activity, so it is unsuitable during pregnancy and may complicate anti-androgen treatment.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trial.
    Namazi N; Esfanjani AT; Heshmati J; Bahrami A · Pakistan journal of biological sciences : PJBS · 2012
    Randomized trial50 participantsAnti-Inflammatory Support forStinging Nettle
  2. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.
    Akbar Karami A; Sheikhsoleimani M; Reza Memarzadeh M; Haddadi E; Bakhshpour M; Mohammadi N; Mehdi Mirhashemi S · Pakistan journal of biological sciences : PJBS · 2021
    Randomized trial60 participantsAnti-Inflammatory Support forStinging Nettle
  3. Safety, Tolerability, and Efficacy of Hox Alpha, a Dry Extract from Stinging Nettle Leaves versus OTC NSAIDs in Osteoarthritis: A Retrospective, Propensity-Matched 12-Week Analysis from the German Pain e-Registry (SIPHARO Study).
    Überall MA; Küster MA; Müller-Schwefe PCG; Müller-Schwefe GHH · Journal of pain research · 2026
    Cohort study2,146 participantsAnti-Inflammatory Support forStinging Nettle
  4. [Recommendations of the DGRh Committee on Complementary Medicine and Nutrition on the application of selected phytotherapeutic drugs and herbal medicines in rheumatology].
    Keyßer G; Seifert O; Frohne I; Michalsen A; Pfeil A; Reuß-Borst M; Sander O · Zeitschrift fur Rheumatologie · 2025
    Guideline / consensusAnti-Inflammatory Support forStinging Nettle
  5. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
    C Randall, H Randall, F Dobbs, C Hutton, H Sanders · Journal of the Royal Society of Medicine · 2000
    Randomized trial27 participantsAnti-Inflammatory Support forStinging Nettle
  6. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  7. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  8. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  9. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  10. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  11. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  12. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  13. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  14. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  15. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto