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NutraSpray Melatonin 1.5 mg Orange Flavor

Source Naturals
4.7
★ ★ ★ ★ ★
(1438 ratings)
Melatonin 1.5 mg
Product Image
Score77
The 1.5 mg oral spray provides moderate sleep-onset support, with no sustained-release coverage as the main trade-off.
How scoring works
Quantity:2 Liquid(s) • (59 servings)
Goals:
Sleep Support

Score 77

The 1.5 mg oral spray provides moderate sleep-onset support, with no sustained-release coverage as the main trade-off.
How scoring works
$9.98($0.16 per serving)
Pure Formulas
$ 10.15
iHerb
$ 10.15
Walmart
$ 10.15
Vitacost
$ 9.98
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Analysis

Melatonin is supplied at 1.5 mg in one oral spray. The amount fits a common sleep-onset range, although some users may need less. The clearly listed amount makes dose comparison simple.

The main benefit is support for circadian timing and falling asleep when a delayed schedule is the problem. The format is suited to relatively quick delivery for sleep onset. It does not add a separate pathway for physical tension or daytime stress resilience.

The 59-serving container provides a reasonable trial period. Vitamin B6 at 1.5 mg is clearly disclosed but adds little to the focused sleep-timing effect. Melatonin can still cause morning drowsiness or vivid dreams, especially when taken too late.

Who is it for
  • Adults seeking support for sleep timing or delayed onset
  • People who prefer fast bedtime delivery
Best for
  • Sleep-onset support
  • Circadian-timing routines

Pros

  • 1.5 mg melatonin amount is clearly listed
  • Format supports quick bedtime delivery
  • 59 servings per container
  • Vitamin B6 amount is disclosed separately

Cons

  • No sustained-release feature for nighttime awakenings
  • Covers only the circadian pathway
  • Vitamin B6 adds little sleep-specific value

Warnings

  • The 1.5 mg melatonin serving may cause next-day drowsiness, vivid dreams, headache, or dizziness.
  • Do not drive or perform safety-sensitive work after taking melatonin or the next morning if alertness is impaired.
  • Alcohol, sleep medicines, and other sedatives can add to melatonin-related drowsiness.

Nutrient quality

86 Highest impact

The liquid or dissolving delivery may support prompt use around bedtime. The modest 1.5 mg melatonin amount is well aligned with routine sleep-onset use.

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Ingredient transparency

84 Highest impact

Every supplied active ingredient has a specific amount and understandable name. Serving count is available, but intake directions and inactive ingredients are absent from the supplied label details.

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Customer satisfaction

69 High impact

The supplied aggregate rating is strong and the review volume adds useful statistical stability. No review text is provided to check recurring complaints or product-specific experiences.

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Value for money

66 High impact

Serving economics appear limited relative to the clearly disclosed melatonin amount. Minor extra ingredients do not add much practical value beyond the core melatonin dose.

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Report analysis

Goals

Sleep Support
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageA- Formula Quality
Melatonin · 1.5 mg

Melatonin at 1.5 mg directly supports sleep timing and onset. The spray gives a clearly measured amount, although it sits just above the most physiologically modest range.

Low-dose vitamin B6 adds little direct sleep support and does not create meaningful pathway breadth. Melatonin can still cause morning drowsiness or vivid dreams in sensitive users.

Study evidence
Melatonin Supportive 181 studies
Vitamin B6 Disputed 7 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
1.5 mg
Melatonin
1.5 mg
Adults 18–50
Report overview
Melatonin · 1.5 mg OverallScore68
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

The spray format supports rapid onset, though no sustained-release technology is identified. The 1.5 mg dose is clearly supplied in one spray and fits the physiologically aligned range. Cost efficiency is moderate, although independent purity certification is not provided.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  3. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  4. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  5. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  6. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  7. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  8. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  9. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  10. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  11. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  12. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  13. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  14. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  15. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  16. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6