5-HTP 100 mg
Solgar
5-HTP 100 mg
4.7
★ ★ ★ ★ ★
(1804 ratings)
Valerian 100 mg
5-HTP 100 mg
Vitamin B6 10 mg
Score 75.0
A Solgar blend of 5-HTP, Valerian, and Vitamin B6 targeting mood, stress, and sleep support. Reputable brand with a synergistic formula, though dosages for Valerian and B6 are moderate.
Quantity: 90 Capsule(s)Servings size: 1 Vegetable Capsule(s) (90 servings)
Selected goals:
Other goals:
Stress Relief
Mood Support
Sleep Support
Energy
Brain Health
leaderboard Score 75.0
A Solgar blend of 5-HTP, Valerian, and Vitamin B6 targeting mood, stress, and sleep support. Reputable brand with a synergistic formula, though dosages for Valerian and B6 are moderate.
insights Analysis
Solgar 5-HTP 100 mg combines 100mg of 5-HTP (from Griffonia simplicifolia seed extract), 100mg of Valerian extract, and 10mg of Vitamin B6 (as Pyridoxine Hydrochloride). This formulation is designed to address mood, stress, and sleep support by leveraging the serotonin precursor benefits of 5-HTP, the calming properties of Valerian, and the crucial cofactor role of Vitamin B6 in neurotransmitter synthesis. Online reviews generally praise Solgar's quality, though some users note the price. Nutritionists recognize the individual benefits of these ingredients, particularly the importance of B6 for 5-HTP conversion. The dosages are effective, with 100mg of 5-HTP being a standard dose, but the Valerian quantity is on the lower side compared to standalone products focusing solely on its sedative effects. This product is best suited for individuals seeking a comprehensive, albeit moderately dosed, approach to emotional well-being and sleep from a trusted brand.
- Contains a synergistic blend of 5-HTP, Valerian, and Vitamin B6, which work together to enhance mood, reduce stress, and improve sleep.
- Produced by Solgar, a highly reputable brand known for its quality and stringent manufacturing standards.
- The 100mg dose of 5-HTP is a commonly recommended and effective amount for targeting mood and sleep support.
- The 100mg dose of Valerian extract is relatively low compared to many standalone Valerian supplements, potentially offering less pronounced sedative effects.
- The 10mg dose of Vitamin B6, while sufficient as a cofactor, is lower than what's found in many dedicated B-complex or standalone B6 supplements.
- The price per serving is on the higher side compared to several alternative products that offer similar or greater potencies of the key ingredients.
$24.29($0.26 per serving)
 Vitacost | $ 24.29 | |
 iHerb | $ 25.49 | |
 Amazon | $ 26.99 | |
 Pure Formulas | $ 26.99 | |
 Daily Vita | $ 29.70 |
bolt Effectiveness for goals
5-HTP is a precursor to serotonin, a neurotransmitter involved in regulating mood, appetite, and sleep. Supplementing with 5-HTP can help increase serotonin levels in the brain. This may support feelings of well-being and promote healthy sleep patterns.
Valerian extract is traditionally used to support relaxation and promote restful sleep. It is thought to work by increasing levels of gamma-aminobutyric acid (GABA) in the brain, a neurotransmitter that helps calm nerve activity. This calming effect can contribute to a reduction in feelings of restlessness.
Vitamin B6 is a crucial cofactor in the conversion of 5-HTP into serotonin in the brain. Adequate B6 levels are necessary for this conversion process to occur efficiently. Therefore, its presence can enhance the effectiveness of 5-HTP supplements.
Magnesium is an essential mineral involved in over 300 biochemical reactions in the body, including those related to nerve and muscle function. It contributes to electrolyte balance and normal psychological function. Magnesium can also support a calm mood and healthy sleep.
Some individuals choose to combine 5-HTP and Valerian extract to potentially support both mood and sleep. 5-HTP focuses on serotonin pathways, while Valerian is thought to influence GABA. This combination aims to provide a more comprehensive approach to relaxation and sleep support.
schedule Dosage, timing & forms
Supplements containing 5-HTP and valerian extract are often suggested for evening or before bedtime use. This timing aligns with their common use to support relaxation and sleep. Taking them with a meal may help reduce potential stomach upset for some individuals.
Vitamin B6 acts as a cofactor in the conversion of 5-HTP into serotonin within the body. This process is crucial for the intended effects of 5-HTP. Both pyridoxine hydrochloride and pyridoxal 5-phosphate are forms of B6 that can support this conversion.
Valerian extract and 5-HTP are often found together in formulations aimed at relaxation or sleep support. Both ingredients are known to influence the central nervous system. When combined, it is generally recommended to follow the product's dosage instructions and consider taking them in the evening.
Common dosages for 5-HTP range, but 100mg is a frequent amount found in supplements, particularly when combined with ingredients like B6. Vitamin B6 is often included to support the conversion of 5-HTP. It's usually suggested to follow label instructions.
Magnesium glycinate is generally considered to have higher bioavailability and better absorption compared to magnesium oxide, which is often used for its higher elemental magnesium content. Glycinate is less likely to cause digestive upset. Timing can vary, but magnesium is commonly taken with food to minimize potential stomach discomfort.
health_and_safety Safety & interactions
5-HTP can increase serotonin levels in the brain. Combining it with antidepressant medications, particularly selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors (MAOIs), may lead to an excessive accumulation of serotonin, a condition known as serotonin syndrome. Symptoms can range from mild (agitation, confusion) to severe (fever, seizures). It is crucial to consult a healthcare professional before combining 5-HTP with any antidepressant medications.
Valerian extract may cause drowsiness and can enhance the effects of other central nervous system depressants, such as sedatives, anxiolytics, and alcohol. This combination could lead to increased sedation, impaired coordination, and slowed breathing. It is advisable to avoid combining Valerian with these substances without consulting a healthcare provider.
Both 5-HTP and Valerian extract have properties that may induce drowsiness or promote relaxation. Combining them could potentially result in additive sedative effects. While generally not considered a severe interaction, individuals may experience increased sleepiness or impaired alertness, so caution is advised.
Vitamin B6 acts as a crucial cofactor in the conversion of 5-HTP into serotonin within the body. While it supports the intended action of 5-HTP, taking very high doses of B6 alongside 5-HTP could theoretically lead to faster peripheral conversion, potentially limiting serotonin availability in the brain. However, the amounts typically included in supplements are generally considered safe and beneficial for this process.
Magnesium supplements can interact with several medications, including certain antibiotics (e.g., tetracyclines, quinolones), diuretics, and proton pump inhibitors. It may also affect the absorption of bisphosphonates (for osteoporosis) and thyroid hormones. It is important to space out magnesium intake from these medications by at least 2-4 hours, or consult a healthcare provider for specific advice.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin B6 (Pyridoxine Hydrochloride, Pyridoxal 5-Phosphate) | 10 mg |
| Magnesium (Magnesium Oxide, Magnesium Glycinate) | 50 mg |
| 5-HTP (Griffonia simplicifolia Seed Extract) | 100 mg |
| Valerian extract | 100 mg |
Categories
5-HTP 85.0
The 100mg dose of 5-HTP is a common and clinically studied amount for supporting mood and sleep, aligning well with typical recommended dosages for effectiveness in promoting serotonin production.
Vitamin B6 50.0
The 10mg dose of Vitamin B6 is sufficient as a cofactor for 5-HTP conversion, but it is a relatively low amount compared to many dedicated B-complex supplements or standalone B6 products available, which often provide significantly higher potencies.
Valerian 40.0
The 100mg Valerian extract is on the lower end when compared to many standalone Valerian supplements that often contain significantly higher doses, which might limit its individual impact for strong sedative effects related to sleep and relaxation.
Goals
Mood Support 85.0
5-HTP is a direct precursor to serotonin, a key neurotransmitter for mood regulation, with Vitamin B6 acting as a vital cofactor and Valerian assisting in calming anxiety, all synergistically supporting emotional balance and mood.
Sleep Support 85.0
5-HTP assists in serotonin and melatonin production, essential for healthy sleep cycles, while Valerian is a traditional herbal remedy known for its sedative effects, working together to promote restful sleep.
Stress Relief 80.0
Valerian is widely recognized for its anxiolytic properties that help reduce stress, and 5-HTP can aid in maintaining emotional balance by supporting serotonin levels, making this product effective for stress management.
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