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Ubiquinol 100 mg

NOW
4.8
★ ★ ★ ★ ★
(15063 ratings)
Coenzyme Q-10 100 mg
Product Image
Score86
100 mg of ubiquinol is a strong single-ingredient option with solid value. Its main trade-off is the standard dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
Quantity:60 Softgel(s) • (60 servings)
Goals:
Cardiovascular Support
Heart Health
Energy
Anti-Aging
Anti-Inflammatory Support
Metabolism Boost

Score 86

100 mg of ubiquinol is a strong single-ingredient option with solid value. Its main trade-off is the standard dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works

Also available as

2 options
120 servings Coenzyme Q-10 100 mg • 120 Softgel(s) • 120 servings $53.88 ($0.44 per serving) 200.00mg • 60 Softgel(s) servings Coenzyme Q-10 200 mg • 60 Softgel(s) • 60 servings $34.70 ($0.57 per serving)
$27.97($0.46 per serving)
iHerb
$ 30.61
Vitacost
$ 32.45
Pure Formulas
$ 27.97
Daily Vita
$ 28.90
Report prices

Analysis

The 100 mg serving uses ubiquinol, giving a clear and focused CoQ10 option. The amount is best suited to people looking for a standard intake rather than a broad multi-ingredient formula.

The label clearly identifies the CoQ10 form and the amount per serving. Value is reasonable, though alternatives may offer a better balance of form and quantity, and the simple formula makes comparison with other CoQ10 products easier.

The strongest practical fit is cardiovascular support, with related assessments also supporting general cardiovascular and energy-focused use. The main decision is whether 100 mg and the ubiquinol form match the user's preferred dose and budget.

Who is it for
  • Adults seeking a standard-dose CoQ10 supplement
  • People who prefer ubiquinol in softgel(s)
  • Users focused on cardiovascular support
Best for
  • Cardiovascular Support support
  • Heart Health support
  • Energy support

Pros

  • Clearly stated 100 mg amount
  • Focused ubiquinol formula
  • Good disclosure of form and serving amount
  • Simple format makes alternatives easy to compare

Cons

  • 100 mg may not match users seeking a lower or higher amount
  • Ubiquinol may cost more than basic ubiquinone options
  • Single-active formula provides no complementary nutrients

Warnings

  • CoQ10 can affect the response to warfarin; people using warfarin should discuss this ingredient with the clinician managing anticoagulation.
  • CoQ10 may add to the effect of blood-pressure-lowering medicines, so users taking them may need appropriate monitoring.

Nutrient quality

95 Highest impact

Ubiquinol supplies the reduced form in a softgel suited to fat-soluble CoQ10. The dose is well aligned with general maintenance and common targeted use, while the focused design avoids unrelated actives.

Ingredient transparency

82 Highest impact

The active amount is clearly disclosed and no blend hides it. Complete daily-use directions and inactive ingredients are not supplied.

Customer satisfaction

71 High impact

The aggregate rating is favorable, and the very large review count makes it stable. No detailed feedback is supplied, so repeated complaints and purpose fit cannot be judged.

Value for money

92 Highest impact

The absorbed form, useful dose, and favorable serving economics create strong value. Incomplete inactive-ingredient details are the main remaining value limitation.

Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy production in heart muscle and adds antioxidant protection. The reduced form is especially useful when CoQ10 status is low, including depletion associated with statin use.

The 100 mg amount is clearly disclosed and well aligned with targeted daily support. A one-softgel serving and the more absorbable ubiquinol form make the formulation simple and efficient.

Study evidence
Coenzyme Q-10 Supportive 89 studies
Heart Health
Heart Health
Impact
Highest effect
A+ Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

CoQ10 directly supports energy production in heart tissue and provides antioxidant protection. The disclosed amount is well aligned with targeted cardiovascular use.

The reduced ubiquinol form is directly usable and offers strong absorption potential. The focused formula has strong depth but does not address lipids, vascular tone, or homocysteine.

Study evidence
Coenzyme Q-10 Supportive 114 studies
Energy
Energy
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol provides the reduced form of CoQ10 for mitochondrial electron transport and cellular energy production. The softgel supplies a well-targeted amount with strong absorption potential.

The focused active has meaningful depth for mitochondrial support but does not address nutrient deficiencies or stress-related fatigue pathways. People using warfarin should note that CoQ10 may reduce its anticoagulant effect.

Study evidence
Coenzyme Q-10 Supportive 32 studies
Anti-Aging
Anti-Aging
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy and antioxidant protection in tissues with high energy demand. The reduced form and useful amount are well aligned with age-related CoQ10 needs.

The focused formula offers strong depth but does not address structural tissues or inflammatory pathways. A softgel is appropriate for this fat-soluble active.

Study evidence
Coenzyme Q-10 Supportive 6 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol at 100 mg provides meaningful mitochondrial antioxidant support and may help moderate several inflammatory markers. The reduced CoQ10 form and softgel delivery favor absorption.

Its action is supportive and concentrated on oxidative stress rather than direct control of several inflammatory enzymes. The label also does not name a branded source or independent quality verification.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B+ Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Coenzyme Q-10 · 100 mg

Ubiquinol directly supports mitochondrial energy production in a readily absorbed form. The amount is appropriate for maintenance, though it is not intended as a direct thermogenic stimulant.

Clear labeling and the reduced CoQ10 form strengthen confidence in the active contribution. The streamlined design provides focused mitochondrial support rather than broad pathway coverage.

Study evidence
Coenzyme Q-10 Disputed 11 studies

Ingredients

IngredientAmount per serving
Ubiquinol (CoQ10)
 100 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 (CoQ10) · 100 mg OverallScore92
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

Ubiquinol provides the better-absorbed reduced form. The clearly stated dose aligns with the targeted range. Its price efficiency is close to the collection norm.

View ingredientView products
Loading alternative details
87 Performance

Extra Strength Ubiquinol 200 mg

NOW
The reduced ubiquinol form at 200 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided quality and goal assessments are stronger than the original, although the ingredient list still does not provide independent testing or certification details.
85 Performance

Mega Ubiquinol CoQ10 100 mg

Qunol
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided collection and goal assessments are well aligned, although the ingredient list still does not provide independent testing or certification details.
85 Performance

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support 100 mg

Life Extension
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. The provided collection and goal assessments are well aligned, although the added shilajit makes the formula less focused and may not suit people seeking CoQ10 alone.
87 Budget

Mega CoQ10 Ubiquinol 100 mg

Qunol
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. Its lower serving cost improves routine value compared with the original; the ingredient list still does not provide independent testing or certification details.
86 Budget

Ubiquinol 100 mg

NOW
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. Its lower serving cost improves routine value compared with the original; the ingredient list still does not provide independent testing or certification details.
87 Budget

QH-absorb 100 mg

Jarrow Formulas
The reduced ubiquinol form at 100 mg supports absorption and keeps the formula closely aligned with CoQ10 use. Its lower serving cost improves routine value compared with the original; the ingredient list still does not provide independent testing or certification details.
87 Value

CoQ10 200 mg

California Gold Nutrition
A clearly stated ubiquinone dose at 200 mg provides a focused CoQ10 formula without unrelated active ingredients. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; Ubiquinone is the oxidized form, so people specifically seeking ubiquinol may prefer another option.
84 Value

High Absorption CoQ10 200 mg

Doctor's Best
Ubiquinone at 200 mg is paired with black pepper extract to support absorption, adding a practical feature to a focused CoQ10 formula. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; Black pepper extract can affect how some medicines are handled, so medication users should check suitability.
79 Value

Ubiquinol 100 mg

Qunol
Named Kaneka ubiquinol at 100 mg gives clear disclosure of the reduced CoQ10 form, which is often chosen for easier absorption. Strong provided quality and goal assessments combine with favorable serving economics, improving the balance of formulation and value; the ingredient list still does not provide independent testing or certification details.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewAnti-Aging forCoenzyme Q-10
  2. Coenzyme Q10 Supplementation in Aging and Disease.
    Hernández-Camacho JD; Bernier M; López-Lluch G; Navas P · Frontiers in physiology · 2022
    Narrative reviewAnti-Aging forCoenzyme Q-10
  3. Coenzyme Q10, a cutaneous antioxidant and energizer.
    Hoppe U; Bergemann J; Diembeck W; Ennen J; Gohla S; Harris I; Jacob J; Kielholz J; Mei W; Pollet D; Schachtschabel D; Sauermann G; Schreiner V; Stäb F; Steckel F · BioFactors (Oxford, England) · 1999
    Clinical trialAnti-Aging forCoenzyme Q-10
  4. Supplements and Drugs Are Associated With Biological Age in a Cohort of Exceptionally Healthy Individuals.
    Pabis K; Wang W; Selvarajoo K; Budovskaya YV; Sorrentino V; Gruber J; Kennedy BK · Aging cell · 2026
    Cross-sectional study4,260 participantsAnti-Aging forCoenzyme Q-10
  5. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsAnti-Aging forCoenzyme Q-10
  6. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  7. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  8. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  9. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  10. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  12. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  13. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  14. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  15. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  16. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  17. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  18. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  19. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  20. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  21. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  22. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  23. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Boost forCoenzyme Q-10
  24. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  25. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  26. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  27. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  28. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10