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Vitamin D-3 1000 IU

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4.8
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(28602 ratings)
Vitamin D 1000 IU
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Score87
A simple, well-priced D3 softgel suits adults seeking a maintenance amount. Label-support details beyond the active ingredient are limited.
How scoring works
Quantity:90 Softgel(s) • (90 servings)
Goals:
General Health
Immunity
Energy
Anti-Inflammatory Support
Anti-Aging
Testosterone Support

Score 87

A simple, well-priced D3 softgel suits adults seeking a maintenance amount. Label-support details beyond the active ingredient are limited.
How scoring works
$9.17($0.10 per serving)
iHerb
$ 9.17
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Analysis

Lanolin-derived vitamin D3 provides a well-absorbed form at 1,000 IU per softgel. The oil-friendly softgel format is a sensible match for a fat-soluble vitamin.

The amount fits routine maintenance better than correction of a known deficiency. A single-active formula also makes total vitamin D intake easier to track than a multi-nutrient blend.

Long supply and low serving cost support everyday value. The supplied data do not include all inactive ingredients, intake directions, or independent quality verification, leaving some label details unconfirmed.

Who is it for
  • Adults seeking routine vitamin D maintenance
  • People comfortable with a lanolin-derived ingredient
  • Shoppers who prefer one softgel with one main active
Best for
  • Daily maintenance dosing
  • Simple vitamin D supplementation
  • Long-term value

Pros

  • Uses vitamin D3 rather than D2
  • Discloses the lanolin source
  • Softgel delivery suits a fat-soluble vitamin
  • Clearly states the active amount

Cons

  • Not vegan because the source is lanolin
  • May be too modest for clinician-directed deficiency correction
  • Complete inactive ingredients are not provided
  • Independent verification is not identified

Warnings

  • Account for vitamin D from multivitamins and fortified products before adding the 1,000 IU softgel.
  • People with high blood calcium, kidney stones, or granulomatous conditions should obtain individualized guidance before taking supplemental vitamin D.
  • Vitamin D can raise calcium; users of thiazide diuretics or digoxin should have the combination reviewed by their clinician.

Nutrient quality

92 Highest impact

Lanolin-derived vitamin D3 is a well-regarded and absorbable form in a lipid-friendly softgel. The vitamin D amount fits common maintenance use.

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Ingredient transparency

85 Highest impact

Every listed active has a specific amount. A complete excipient and carrier list is not available in the supplied data.

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Customer satisfaction

77 High impact

The average rating is very strong. The large rating volume provides a reliable satisfaction signal.

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Value for money

95 Highest impact

The supply provides excellent value per effective serving. The formula is not inflated by low-value extras.

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Report analysis

Goals

General Health
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageA Formula Quality
Vitamin D · 1000 IU

Vitamin D3 provides focused support for normal immune function, calcium handling, and skeletal maintenance. The maintenance-level serving and softgel delivery make the formula practical for routine use.

Lanolin sourcing improves traceability, although no independent quality verification is provided. People with high vitamin D intake from other products should account for the combined daily amount.

Study evidence
Vitamin D Supportive 115 studies
Immunity
Impact
Highest effect
A Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Vitamin D · 1000 IU

Vitamin D3 directly supports innate and adaptive immune-cell signaling at a standard maintenance amount. Lanolin sourcing and softgel delivery provide unusually clear form and absorption information.

The single nutrient cannot support mucosal barriers, antioxidant control, and zinc-dependent functions at the same time. Its focused design is most useful for maintaining vitamin D status.

Study evidence
Vitamin D Supportive 85 studies
Energy
Impact
Highest effect
A- Goal FitA Strength of SupportC- CoverageA Formula Quality
Vitamin D · 1000 IU

Vitamin D3 supports immune function, bone maintenance, muscle activity, and calcium absorption. Lanolin sourcing is disclosed and the softgel provides a suitable fat-compatible format.

The 1,000 IU serving is a practical maintenance amount for many adults. Individual need still depends on sun exposure, diet, and vitamin D status.

Study evidence
Vitamin D Supportive 32 studies
Anti-Inflammatory Support
Impact
Highest effect
A Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Vitamin D · 1000 IU

Vitamin D3 directly supports immune regulation and may help keep inflammatory signaling balanced, especially when vitamin D status is low. Its human evidence is stronger for correcting inadequacy than for producing the same response in everyone. Lanolin sourcing and a softgel provide useful traceability and lipid-based delivery.

The maintenance-level dose is clearly disclosed and the cholecalciferol form is appropriate. The focused design offers strong depth for one immune pathway but does not cover direct enzyme inhibition, fatty-acid resolution, or broad antioxidant recycling.

Study evidence
Vitamin D Supportive 101 studies
Anti-Aging
Impact
High effect
B- Goal FitA- Strength of SupportD CoverageA Formula Quality
Vitamin D · 1000 IU

Vitamin D3 provides focused support for bone strength and immune regulation as people age. Vitamin D has solid human evidence for maintaining bone and immune function when intake or blood levels are low.

The 1000 IU softgel is suited to routine maintenance, though individual need depends on diet, sun exposure, and blood levels. The narrow formula offers depth in one foundational area but does not address most cellular aging pathways.

Study evidence
Vitamin D Supportive 50 studies
Testosterone Support
Impact
High effect
C+ Goal FitB Strength of SupportD+ CoverageA Formula Quality
Vitamin D · 1000 IU

Vitamin D provides a relevant route to testosterone support. Dose or form uncertainty limits confidence in the practical contribution.

The formula remains narrow rather than comprehensive. Vitamin D-3 1000 IU is best viewed as targeted support rather than proof of a clinical benefit.

Study evidence
Vitamin D Supportive 56 studies

Ingredients

IngredientAmount per serving
Vitamin D3 (Lanolin)
1000 IU
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
A+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value

Lanolin-sourced vitamin D3 combines clear traceability with lipid-based softgel delivery. The 1000 IU serving suits standard maintenance. No flagged additives are disclosed, but independent verification is absent and cost efficiency is moderate.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Joint association of serum 25-hydroxyvitamin D concentration and body mass index on the acceleration of clinical biomarker-based biological aging.
    Pan Z; Zeng J; Chen Z; Chen S; Yang J; Li H; Wang S; Wang J; Li N; Gong Y; Liu M; Li C · The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Cohort study389,217 participantsAnti-Aging forVitamin D
  2. Serum 25-Hydroxyvitamin D Levels as an Aging Marker: Strong Associations With Age and All-Cause Mortality Independent From Telomere Length, Epigenetic Age Acceleration, and 8-Isoprostane Levels.
    Schöttker B; Hagen L; Zhang Y; Gào X; Holleczek B; Gao X; Brenner H · The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Cohort study9,940 participantsAnti-Aging forVitamin D
  3. Sex-specific associations of serum 25-hydroxyvitamin D concentrations with incident sarcopenia in older adults: A 2-year follow-up study.
    Song S; Lim JY; Kim M; Won CW; Park HY · The journal of nutrition, health & aging · 2025
    Cohort study1,292 participantsAnti-Aging forVitamin D
  4. Vitamin D deficit is associated with accelerated brain aging in the general population.
    Terock J; Bonk S; Frenzel S; Wittfeld K; Garvert L; Hosten N; Nauck M; Völzke H; Van der Auwera S; Grabe HJ · Psychiatry research. Neuroimaging · 2022
    Cross-sectional study1,865 participantsAnti-Aging forVitamin D
  5. Vitamin D intake is associated with dementia risk in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
    Zhao C; Tsapanou A; Manly J; Schupf N; Brickman AM; Gu Y · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort study1,759 participantsAnti-Aging forVitamin D
  6. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsAnti-Inflammatory Support forVitamin D
  7. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  8. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsAnti-Inflammatory Support forVitamin D
  9. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsAnti-Inflammatory Support forVitamin D
  10. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsAnti-Inflammatory Support forVitamin D
  11. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  12. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  13. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  14. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  15. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  16. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  17. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  18. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  19. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  20. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  21. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  22. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  23. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  24. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  25. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  26. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsTestosterone Support forVitamin D
  27. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsTestosterone Support forVitamin D
  28. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsTestosterone Support forVitamin D
  29. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsTestosterone Support forVitamin D
  30. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsTestosterone Support forVitamin D