Flavonoid
Flavonoids are a vast family of plant pigments and phytonutrients, characterized by their polyphenolic chemical structure. These compounds are ubiquitous in the plant kingdom, imparting vibrant colors to fruits and vegetables, and playing crucial roles in plant defense mechanisms against environmental stressors. Their presence in our diet is significant due to their potential health-promoting properties. With over 8,000 distinct compounds identified, flavonoids are categorized into several subgroups, including anthocyanins, flavones, flavonols, flavanones, isoflavones, and flavanols. Each subgroup has a unique chemical structure and is found in different plant sources, contributing to the diverse range of effects observed. For instance, anthocyanins give berries their red and purple hues, while flavanols are abundant in green tea and cocoa. In the human body, flavonoids primarily act as potent antioxidants, effectively neutralizing harmful free radicals and reducing cellular damage caused by oxidative stress. Beyond this, they exhibit anti-inflammatory, antiviral, and anticarcinogenic activities. Research suggests their involvement in supporting cardiovascular health, enhancing cognitive function, and modulating immune responses, making them a subject of extensive scientific interest.
Berries (e.g., blueberries, strawberries, raspberries, European Elder, Acerola)Citrus fruitsApplesGrapesOnionsKaleParsleySoybeansTea (especially Green Tea)CocoaRed wineTurmericGinkgo Biloba
Minimum50 mg
Maximum200 mg
Toxicity Threshold2000 mg
Toxicity EffectHeadache, digestive issues
Impact
High effect
Flavonoids, such as quercetin, can reduce the release of histamine and other inflammatory mediators from mast cells in the gut, calming reactivity. They also reinforce tight junctions and reduce oxidative stress, contributing to a healthier gut barrier.
View goal →
Impact
Moderate effect
Typical dose:50–200 mg (of extract standardized for anthocyanins)
'Flavonoid' is a very broad category. While specific members like anthocyanins show promise for improving microcirculation and reducing eye fatigue, the evidence is not as robust or foundational as the AREDS2 ingredients. A lower priority and more moderate effectiveness rating are more appropriate.
View goal →
add_circle_outline Positive Interactions
Vitamin C
Vitamin C can help regenerate oxidized flavonoids, enhancing their antioxidant capacity and overall effectiveness.
Vitamin E
Working together, flavonoids and Vitamin E provide a comprehensive antioxidant defense, protecting cell membranes from oxidative damage.
Selenium
Selenium, as a component of antioxidant enzymes, can work synergistically with flavonoids to bolster the body's defense against oxidative stress.
Zinc
Zinc supports the function of several antioxidant enzymes, creating a synergistic effect with flavonoids in combating oxidative stress.
Coenzyme Q-10
Flavonoids can enhance the antioxidant network alongside Coenzyme Q-10, supporting cellular energy production and overall antioxidant protection.
Astaxanthin
As powerful antioxidants, Astaxanthin and flavonoids can offer synergistic protection against free radicals and inflammation.
Lycopene
Lycopene, another potent antioxidant, can complement the protective effects of flavonoids, particularly in cell protection against oxidative damage.
carotenoids
Flavonoids and carotenoids (like Lycopene and Astaxanthin) collectively contribute to a broader spectrum of antioxidant and immune support.
Curcumin
Curcumin, known for its potent anti-inflammatory and antioxidant properties, works synergistically with flavonoids to enhance these beneficial effects.
Resveratrol
Resveratrol, another polyphenol, shares similar antioxidant and anti-inflammatory benefits with flavonoids, leading to enhanced protective effects when combined.
Green Tea
Green Tea contains catechins, a type of flavonoid, and combining it with other flavonoids can enhance the overall antioxidant and health-promoting effects.
Gluthathione
Flavonoids can support the body's natural Glutathione production and activity, enhancing the master antioxidant system for better detoxification and oxidative stress reduction.
Glutathione
Flavonoids can support the body's natural Glutathione production and activity, enhancing the master antioxidant system for better detoxification and oxidative stress reduction.
73 Best 
CoQ10-Plus
Irwin Naturals
4.8
★★★★★
(133 ratings)
Flavonoid: 25 mg
This blend combines CoQ10 with Omega-3s and a variety of supportive herbs in a liquid softgel, offering broad daily wellness support for those seeking a multi-ingredient approach.
82 Value 
Acerola Cherry Chewable C 500 mg Fruit Flavor
Source Naturals
5.0
★★★★★
(1 ratings)
Flavonoid: 24 mg
This chewable Vitamin C supplement offers a robust 1000mg dose per serving, blending two forms of Vitamin C with bioflavonoids for broad support, all in a convenient fruit-flavored tablet.
No image
Ultra Potent-C 500
Metagenics
5.0
★★★★★
(9 ratings)
Flavonoid: 16 mg
This product delivers a solid dose of Vitamin C with small amounts of supporting nutrients, but the potency of its Glutathione and Cysteine components is notably low.
78 Value 
Wellness Formula
Source Naturals
4.7
★★★★★
(17047 ratings)
Flavonoid: 60 mg
This formula combines a broad array of vitamins, minerals, and traditional herbs into one product, primarily supporting immune system function and general health.
82 Budget 
Wellness Formula
Source Naturals
4.2
★★★★★
(40 ratings)
Flavonoid: 60 mg
This product delivers a powerful combination of high-dose immune vitamins and minerals with a very extensive blend of traditional herbs, making it a comprehensive choice for immune support and overall wellness.
76 Budget 
Wellness Formula
Source Naturals
4.8
★★★★★
(4880 ratings)
Flavonoid: 60 mg
This formula combines a broad array of vitamins, minerals, and traditional herbs into one product, primarily supporting immune system function and general health.
80 Best 
Wellness Formula
Source Naturals
4.7
★★★★★
(5204 ratings)
Flavonoid: 60 mg
This tablet formula offers a wide array of vitamins, minerals, and traditional herbs in one product, primarily supporting immune system function and general health, with good value.
82 Best 
Advanced Therapeutics Lutein Rx-Eye
NaturesPlus
4.5
★★★★★
(222 ratings)
Flavonoid: 125 mg
This supplement offers targeted vision support with FloraGLO Lutein and Zeaxanthin, combined with a comprehensive blend of antioxidants and essential vitamins and minerals for overall health.
82 Budget 
Hair Skin & Nails
Futurebiotics
4.5
★★★★★
(2740 ratings)
Flavonoid: 50 mg
This supplement is a comprehensive blend of vitamins, minerals, amino acids, and botanicals specifically formulated to support the health and appearance of hair, skin, and nails.
83 Budget 
Men Multivitamin + Supporting Herbs Iron Free
Super Nutrition SimplyOne
4.7
★★★★★
(985 ratings)
Flavonoid: 30 mg
A comprehensive, iron-free multivitamin for men, providing a broad range of vitamins, minerals, and supportive botanicals in generally strong dosages.
87 Best 
TurmeriPro
Oregon's Wild Harvest
4.7
★★★★★
(20 ratings)
Flavonoid: 112 mg
This product combines Turmeric extract, Bromelain, and Citrus Bioflavonoids in a capsule, aiming to support your body's natural inflammatory response and contribute to joint comfort.
78 Budget 
Mega-Kid Berry
Source Naturals
4.6
★★★★★
(978 ratings)
Flavonoid: 15 mg
This is a comprehensive berry-flavored multivitamin wafer packed with essential vitamins, minerals, and a range of botanical extracts, designed to support general well-being.
85 Value 
Metabolic C 500 mg
Source Naturals
4.8
★★★★★
(220 ratings)
Flavonoid: 100 mg
This product delivers Vitamin C in the specialized PureWay-C form with added citrus bioflavonoids, offering a convenient way to support daily wellness at an accessible price.
85 Budget 
Multiple Assorted Fruit Flavors
Bluebonnet Rainforest Animalz
4.4
★★★★★
(10 ratings)
Flavonoid: 20 mg
This is a comprehensive, flavored chewable multivitamin for children, offering a wide range of essential nutrients, including some higher-quality forms and plant-based compounds.
88 Best 
Super Antioxidant Formula
Bluebonnet
5.0
★★★★★
(12 ratings)
Flavonoid: 100 mg
This is a comprehensive antioxidant blend featuring key vitamins, minerals, and a wide range of botanical extracts and specialized compounds for broad cellular support.
75 Best 
Eye Antioxidant
Bluebonnet
4.8
★★★★★
(6 ratings)
Flavonoid: 100 mg
This product combines a robust mix of vitamins, minerals, and antioxidants to support eye health and provide general cellular protection.
88 Best 
Eye Antioxidant
Bluebonnet
4.7
★★★★★
(970 ratings)
Flavonoid: 100 mg
A comprehensive blend of vitamins, minerals, and antioxidants, with a primary focus on supporting eye health and general cellular protection through well-chosen ingredient forms.
78 Best 
Vitamin C with Flavonoids
Thorne
4.8
★★★★★
(8232 ratings)
Flavonoid: 75 mg
This product delivers a standard dose of ascorbic acid Vitamin C and citrus bioflavonoids, providing reliable daily support from a recognized brand.
75 Budget 
Enhanced Energy Teen Stay Sharp Multivitamin
KAL
4.6
★★★★★
(388 ratings)
Flavonoid: 50 mg
This multivitamin for teens provides a wide range of vitamins, minerals, and specialized blends to support general health, energy, and cognitive function.
75 Value 
Quercetin Complex
Natrol
4.7
★★★★★
(1283 ratings)
Flavonoid: 66 mg
This complex combines a high dose of Vitamin C with a substantial amount of Quercetin and additional bioflavonoids, catering to those seeking enhanced flavonoid and antioxidant support beyond basic Vitamin C.
83 Best 
Vision Sharp Multi-Nutrient Eye Health
Irwin Naturals
4.5
★★★★★
(909 ratings)
Flavonoid: 30 mg
A comprehensive softgel supplement designed to support vision and overall eye health, blending essential vitamins, minerals, omega-3s, and targeted botanicals like lutein and bilberry for daily maintenance.
Average$27.08
Median$24.99
Average$0.74
Median$0.60