Choline/Inositol 500 mg/500 mg

Choline/Inositol 500 mg/500 mg

Solgar4.8 (4,582 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 50 servings
Goals

Product analysis

74 out of 100

Choline/Inositol 500 mg/500 mg provides choline that helps maintain normal liver function, especially when intake is low. Its role in nerve signaling does not establish immediate improvements in memory or focus.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality60

Choline is identified as choline bitartrate. The inositol form is unspecified, so its quality cannot be compared confidently.

Ingredient Transparency81

Both amounts are stated. The choline form is named, but the inositol form is unspecified.

Value For Money75

Choline offers reasonably favorable value for the amount provided. That does not establish a separate value contribution from inositol.

Customer Satisfaction90

Customer feedback is very positive across a large number of ratings. That provides a broad satisfaction picture without proving cognitive benefits.

Product Focus79

The clearest purpose is choline nutrition and normal liver support. Memory, attention and faster toxin removal are not established benefits of the combination.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.27
Customer rating
4.8 · 4,582 ratings
Report analysis

Goals

Liver & Detox
Impact
Highest effect
B+ Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Choline · 500 mg
Study evidence
Choline Supportive 6 studies
Cognitive Support
Impact
Highest effect
B+ Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Choline · 500 mg
Study evidence
Choline Supportive 76 studies
Mental Focus
Impact
High effect
B+ Ingredient FitC PathwaysB- EvidenceA+ Formulation Logic
Choline · 500 mg
Study evidence
Choline Supportive 22 studies

Ingredients

IngredientAmount per servingScore
Choline (Choline Bitartrate)
500 mg 82
Inositol
500 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
C+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB Value
Each serving supplies 500 mg of choline, a substantial amount, at a moderate cost relative to the amount. It uses Choline Bitartrate, a choline source for systemic use. The ingredient list indicates flow agents.
How this ingredient is rated

Active Ingredient Quality & Bioavailability68

It uses Choline Bitartrate, a choline source for systemic use. The ingredient list indicates flow agents.
Choline Form Efficacy & Bioavailability
It uses Choline Bitartrate, a choline source for systemic use.
Formula Purity & Excipient Quality
The ingredient list indicates flow agents.

Dose, Safety & Label Transparency100

The label lists 500 mg of choline per serving. The source is Choline Bitartrate.
Choline Dose by Declared Basis
Each serving provides 500 mg of choline, a substantial amount.
Elemental Yield Transparency
The label states the choline amount and names Choline Bitartrate as its source.

Value75

The cost relative to the choline amount is moderate.
Price per 100 mg of Declared Choline Basis
The cost relative to the choline amount is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsCognitive Support forCholine
  2. Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
    Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
    Cohort study125,594 participantsCognitive Support forCholine
  3. Choline intake during pregnancy and child cognition at age 7 years.
    Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
    Cohort study895 participantsCognitive Support forCholine
  4. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forCholine
  5. Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
    Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
    Randomized trial52 participantsCognitive Support forCholine
  6. Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
    Guideline / consensusLiver & Detox forCholine
  7. Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
    Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
    Cross-sectional study20,643 participantsLiver & Detox forCholine
  8. Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
    Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
    Observational study80 participantsLiver & Detox forCholine
  9. Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
    Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
    Single-arm trial10 participantsLiver & Detox forCholine
  10. 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
    Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
    Cohort study88 participantsLiver & Detox forCholine
  11. Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder.
    Wozniak JR; Fink BA; Fuglestad AJ; Eckerle JK; Boys CJ; Sandness KE; Radke JP; Miller NC; Lindgren C; Brearley AM; Zeisel SH; Georgieff MK · Journal of neurodevelopmental disorders · 2021
    Randomized trial31 participantsMental Focus forCholine
  12. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort.
    Poly C; Massaro JM; Seshadri S; Wolf PA; Cho E; Krall E; Jacques PF; Au R · The American journal of clinical nutrition · 2012
    Cohort study1,391 participantsMental Focus forCholine
  13. Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
    Obeid R; Derbyshire E; Schön C · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis30 studies pooledMental Focus forCholine
  14. Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
    Akison LK; Kuo J; Reid N; Boyd RN; Moritz KM · Alcoholism, clinical and experimental research · 2019
    Systematic reviewMental Focus forCholine
  15. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
    Ross RG; Hunter SK; McCarthy L; Beuler J; Hutchison AK; Wagner BD; Leonard S; Stevens KE; Freedman R · The American journal of psychiatry · 2013
    Randomized trialMental Focus forCholine